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The map label for this gene is aapM [H]

Identifier: 146340848

GI number: 146340848

Start: 4088541

End: 4090061

Strand: Reverse

Name: aapM [H]

Synonym: BRADO3911

Alternate gene names: 146340848

Gene position: 4090061-4088541 (Counterclockwise)

Preceding gene: 146340849

Following gene: 146340847

Centisome position: 54.85

GC content: 65.81

Gene sequence:

>1521_bases
ATGACCGACATCACAGCCTCGAACTTCATCCGCCAGGACATGGCTGGCGAGCGTCCCGCGCCGATCAAGACCACCGGCGT
CATCGGCTTCGTTCGCACGCAGCTGCTGAACTCGCCGACCAACATCCTGCTCACTCTGGTGAGCGCGTTGCTGATCTGGT
TCACCGTGATTCCAGCGCTGCAGTTCCTGCTTGTCGACGCCGTCTGGGTCGGCAAGGATCGCGAGGCCTGTCTGGCGCAG
AACGCCGGTCACCCGGTCGGCGCGTGCTGGCCGTACATCACGGCGAAGTTCAGCCAGTTCATGTACGGCTTCTACCCCGA
GGCCCAGCGCTGGCGTGTGAACCTGACCTATGTGCTGTTCGTTGCGCTGCTGGCGCCGCTGATGATCAGAAGCGTGCCGG
CGAAGACTCTCAATGCCGGTCTGTTCCTGGTCGCATTGCCAGTGGTCGCCTTCTTCCTGCTGTACGGCGGCGGCCTCTCG
GGCTTCGGCGTGAGCTGGACGGCGAGCGTCCTGTCCCTGTTCGCGGAGAGCGTCGATAGCGCCGGCAATGCTTTGGTCCG
CAGCGGAGCCGGCGTTCCCGTGATCGGCATGCTGTTCTGGCTCATGGGCAAGCTCGTGGTCCTGATCGGGACGGTGGCCT
CGCTGGTGATCTGGCCGTTGCTCTGGCTGCGTGATCAACTGCAGGCCTCGCAGCAGCCGGTGTGGACCGATCTCGTCATT
ACGGCGGTCGCTGTCTCGGCGCTGGTGTTCGTCATCGGCGGCGGGAGCAGGGCGCTGCGCAGCGTGATCGGCACCATCGC
GACTTTCGTCGGGATCGCGGTCGTGATCGCCGTCATGGGCCTGGATCGCGGCGGCCTGCCGGTCGTCGATACGAGGCTGT
GGGGCGGCATGCTGGTGACGCTGGTCGTCACCGTCATCGGCATCGTCGCGTCGATGCCGATCGGCATCGCGCTGGCGCTC
GGCCGGCGTTCGACCATTCCGCTGATCAGGATCTTCTCGATCGCCTTCATCGAGCTGGTGCGCGGCGTGCCGCTGATCAC
CGTGCTGTTCTTCGCGACCTACATGCTGCCGCTGTTCCTGCCCGGCAACCTCAGGATCGACGGCCTGGTGCGGGCGCTGA
TCGGCGTCGCGCTGTTCTCCGGCGCCTACATGGCCGAGGTGATCCGCGGCGGACTGCAGGCGATCCCGCGCGGCCAGGCG
GAGGCGGCGAGCGCGCTCGGCCTGTCCTGGTGGAAGACCACGAGCTTCATCGTGCTGCCGCAGGCGCTCCGCCACGTCAT
TCCCGGCATCGTCAACAGCTTCATCTCGCTGTTCAAGGATACGTCGCTGGTGTCGATCGTGGCGCTGTTTGACCTGCTCG
GCAGCCTCAAGGCCTCGTTCGCGGATCCGGTCTGGGCGACGCCGACCACGGCCTTCACCGGCTTCGCCTTCACCGGCCTG
ATCTACTTCGCCTTCTGCTTCGGCATGTCACGCTATTCCCTGCTGGTCGAGCGCCGCCTGAACGCGCACCGGCGTAACTG
A

Upstream 100 bases:

>100_bases
AGCGCGATCATGAGCTTCTACAGCTGGCGGCTGGGCAAGAGGCTTGGAGCATGACCAGGCTCGGGGACGAAGACCTCTGG
CGCATGAAGAGATTTCGCGC

Downstream 100 bases:

>100_bases
ACAGAGATCATCGAGTCATCGAACCATGGCTGCAAACTCCATCGTCAGCATCTCCGCGCTCAACAAATGGTACGGCGAAT
TCCACGTGCTGCGGGACGTG

Product: putative amino acid ABC transport, permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 506; Mature: 505

Protein sequence:

>506_residues
MTDITASNFIRQDMAGERPAPIKTTGVIGFVRTQLLNSPTNILLTLVSALLIWFTVIPALQFLLVDAVWVGKDREACLAQ
NAGHPVGACWPYITAKFSQFMYGFYPEAQRWRVNLTYVLFVALLAPLMIRSVPAKTLNAGLFLVALPVVAFFLLYGGGLS
GFGVSWTASVLSLFAESVDSAGNALVRSGAGVPVIGMLFWLMGKLVVLIGTVASLVIWPLLWLRDQLQASQQPVWTDLVI
TAVAVSALVFVIGGGSRALRSVIGTIATFVGIAVVIAVMGLDRGGLPVVDTRLWGGMLVTLVVTVIGIVASMPIGIALAL
GRRSTIPLIRIFSIAFIELVRGVPLITVLFFATYMLPLFLPGNLRIDGLVRALIGVALFSGAYMAEVIRGGLQAIPRGQA
EAASALGLSWWKTTSFIVLPQALRHVIPGIVNSFISLFKDTSLVSIVALFDLLGSLKASFADPVWATPTTAFTGFAFTGL
IYFAFCFGMSRYSLLVERRLNAHRRN

Sequences:

>Translated_506_residues
MTDITASNFIRQDMAGERPAPIKTTGVIGFVRTQLLNSPTNILLTLVSALLIWFTVIPALQFLLVDAVWVGKDREACLAQ
NAGHPVGACWPYITAKFSQFMYGFYPEAQRWRVNLTYVLFVALLAPLMIRSVPAKTLNAGLFLVALPVVAFFLLYGGGLS
GFGVSWTASVLSLFAESVDSAGNALVRSGAGVPVIGMLFWLMGKLVVLIGTVASLVIWPLLWLRDQLQASQQPVWTDLVI
TAVAVSALVFVIGGGSRALRSVIGTIATFVGIAVVIAVMGLDRGGLPVVDTRLWGGMLVTLVVTVIGIVASMPIGIALAL
GRRSTIPLIRIFSIAFIELVRGVPLITVLFFATYMLPLFLPGNLRIDGLVRALIGVALFSGAYMAEVIRGGLQAIPRGQA
EAASALGLSWWKTTSFIVLPQALRHVIPGIVNSFISLFKDTSLVSIVALFDLLGSLKASFADPVWATPTTAFTGFAFTGL
IYFAFCFGMSRYSLLVERRLNAHRRN
>Mature_505_residues
TDITASNFIRQDMAGERPAPIKTTGVIGFVRTQLLNSPTNILLTLVSALLIWFTVIPALQFLLVDAVWVGKDREACLAQN
AGHPVGACWPYITAKFSQFMYGFYPEAQRWRVNLTYVLFVALLAPLMIRSVPAKTLNAGLFLVALPVVAFFLLYGGGLSG
FGVSWTASVLSLFAESVDSAGNALVRSGAGVPVIGMLFWLMGKLVVLIGTVASLVIWPLLWLRDQLQASQQPVWTDLVIT
AVAVSALVFVIGGGSRALRSVIGTIATFVGIAVVIAVMGLDRGGLPVVDTRLWGGMLVTLVVTVIGIVASMPIGIALALG
RRSTIPLIRIFSIAFIELVRGVPLITVLFFATYMLPLFLPGNLRIDGLVRALIGVALFSGAYMAEVIRGGLQAIPRGQAE
AASALGLSWWKTTSFIVLPQALRHVIPGIVNSFISLFKDTSLVSIVALFDLLGSLKASFADPVWATPTTAFTGFAFTGLI
YFAFCFGMSRYSLLVERRLNAHRRN

Specific function: Part of a binding-protein-dependent transport system for L-amino acids, affects the uptake as well as efflux of these amino acids. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI87082239, Length=220, Percent_Identity=55.4545454545455, Blast_Score=248, Evalue=6e-67,
Organism=Escherichia coli, GI1786873, Length=212, Percent_Identity=32.5471698113208, Blast_Score=111, Evalue=9e-26,
Organism=Escherichia coli, GI1788226, Length=207, Percent_Identity=34.2995169082126, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1787030, Length=157, Percent_Identity=35.031847133758, Blast_Score=95, Evalue=8e-21,
Organism=Escherichia coli, GI1788646, Length=214, Percent_Identity=29.4392523364486, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1786874, Length=171, Percent_Identity=26.9005847953216, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787087, Length=147, Percent_Identity=34.0136054421769, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI48994930, Length=228, Percent_Identity=27.6315789473684, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1788645, Length=222, Percent_Identity=27.9279279279279, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1787086, Length=223, Percent_Identity=26.9058295964126, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 54424; Mature: 54292

Theoretical pI: Translated: 10.57; Mature: 10.57

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDITASNFIRQDMAGERPAPIKTTGVIGFVRTQLLNSPTNILLTLVSALLIWFTVIPAL
CCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
QFLLVDAVWVGKDREACLAQNAGHPVGACWPYITAKFSQFMYGFYPEAQRWRVNLTYVLF
HHHHHHHHHCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHEEEHHHHHHH
VALLAPLMIRSVPAKTLNAGLFLVALPVVAFFLLYGGGLSGFGVSWTASVLSLFAESVDS
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
AGNALVRSGAGVPVIGMLFWLMGKLVVLIGTVASLVIWPLLWLRDQLQASQQPVWTDLVI
CCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
TAVAVSALVFVIGGGSRALRSVIGTIATFVGIAVVIAVMGLDRGGLPVVDTRLWGGMLVT
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHH
LVVTVIGIVASMPIGIALALGRRSTIPLIRIFSIAFIELVRGVPLITVLFFATYMLPLFL
HHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHC
PGNLRIDGLVRALIGVALFSGAYMAEVIRGGLQAIPRGQAEAASALGLSWWKTTSFIVLP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
QALRHVIPGIVNSFISLFKDTSLVSIVALFDLLGSLKASFADPVWATPTTAFTGFAFTGL
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
IYFAFCFGMSRYSLLVERRLNAHRRN
HHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TDITASNFIRQDMAGERPAPIKTTGVIGFVRTQLLNSPTNILLTLVSALLIWFTVIPAL
CCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH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HHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8898392 [H]