Click here to switch to the map view.

The map label for this gene is cfa [H]

Identifier: 146340845

GI number: 146340845

Start: 4085291

End: 4086523

Strand: Direct

Name: cfa [H]

Synonym: BRADO3908

Alternate gene names: 146340845

Gene position: 4085291-4086523 (Clockwise)

Preceding gene: 146340844

Following gene: 146340846

Centisome position: 54.79

GC content: 62.69

Gene sequence:

>1233_bases
ATGCCGGACGTCATCCCCGTCACCCCTGACAGCATCGACAAGGTGCTTGCCGATCTGCCTCGTCTGCCCCGTCTCGCCCT
CGGCTTCGGCTCGCGGCTGCGAAAGGGCACGCTCGACGTGACGCTGCCCGATGGCCGCATCGTCCGGCTCGGCGGTGTCG
AGCCGGGGCCGGCAGCGGCCATGATCCTCGCCAATTACGGCTTCGCCTCCGGCATCATCAACGGCGGCGACATCGGCATC
GCCGAAGCGTATCTCAATGGCGACTGGGATACGCCGGACCTGACGCAGTTTCTCTATCTGTTCTGCGTCAACCAGCATTT
GCTGCAGTCGATGCTGGCGGACAAGCCGTTGATCCGGCTTGCCCAGTTGGTGCGGCACTGGTTCAACCGCAACACCAAGC
GGCAGGCCAAGCGCAACATCTACGCCCATTACGACATCGGCAATTCGTTCTACTCGGCGTGGCTCGACCCCAGCATGACC
TATTCCTCGGCCCTGTTCGAGGAGCACACCACGGATCTGACGGCTGCCCAGGCCAACAAGTACAAGCGGCTGGCGGAGGC
GATCGACCTGAAGCCCGGCCAGAAGCTCCTGGAGATCGGCTGCGGCTGGGGCGGCTTCGCGGAGTATGTGGCGAAGACGT
TCAACGCGAAGGTCGTGGGTTTGACGATCAGCGAGCAGCAGCGCGATTTCGCGCAGCGCCGCATCCACGAGGCCGGCCTT
GCCGAGAAGGTCGAGATCCGGCTGCAGGATTATCGCGACGAGCGCGACCGCTACGATCGCATCGCCTCGATCGAGATGAT
CGAGGCCGTCGGCGAAGAGTTCTGGCCAAAATATTTTTCGCAGCTGCGAGACCGTCTGCTCCCGGGCGGCCTTGCCGGTG
TCCAGGCCATTACCATTCAGGACAGCCTGTTTCACCACTACCGGCGCGAGGTCGACTTCATCCAGCGCTACGTTTTTCCC
GGCGGCATGCTGCCGACGCCGCAGATCCTGAAGTCGCTTGGCGAACGGTTTGGCATCCCCGTCATTCGCGAGCGAATTTT
TGGGGAAGATTATGCCAAGACGCTGGCGATCTGGCGCAACAATTTTCGCGCGGCCTGGCCGGATCTGACGCCGGCGGGAT
TCGACGAGCGCTTCCGCCGGCTGTGGGAGTACTATCTGTCGTACTGCGAAGCAGGTTTCCTGTCAGGGAACATCGACGTG
CGCCAGGTGGTGTTTGCCAAATCCGGGGCATAG

Upstream 100 bases:

>100_bases
ACGGCGGCGCGCTCTGCCCGGGCCACCCGTCCAGAAGGCGCCTCATCGGCAGCCGTGCGGGCGGCGCGGGGGTAGAGCCG
ATTGCGTAAATGGACCTGCC

Downstream 100 bases:

>100_bases
TGCCGCTGGCTTACGCAGCACTGGAGACTAGGCTAGGGTCTTCCTAGATCTGCTCTTAAGGAAGCTGCCCAAGGTATTTG
CAATATGACCATTAGAAACG

Product: putative cyclopropane-fatty-acyl-phospholipid synthase (Cfa-like)

Products: NA

Alternate protein names: CFA synthase; Cyclopropane fatty acid synthase [H]

Number of amino acids: Translated: 410; Mature: 409

Protein sequence:

>410_residues
MPDVIPVTPDSIDKVLADLPRLPRLALGFGSRLRKGTLDVTLPDGRIVRLGGVEPGPAAAMILANYGFASGIINGGDIGI
AEAYLNGDWDTPDLTQFLYLFCVNQHLLQSMLADKPLIRLAQLVRHWFNRNTKRQAKRNIYAHYDIGNSFYSAWLDPSMT
YSSALFEEHTTDLTAAQANKYKRLAEAIDLKPGQKLLEIGCGWGGFAEYVAKTFNAKVVGLTISEQQRDFAQRRIHEAGL
AEKVEIRLQDYRDERDRYDRIASIEMIEAVGEEFWPKYFSQLRDRLLPGGLAGVQAITIQDSLFHHYRREVDFIQRYVFP
GGMLPTPQILKSLGERFGIPVIRERIFGEDYAKTLAIWRNNFRAAWPDLTPAGFDERFRRLWEYYLSYCEAGFLSGNIDV
RQVVFAKSGA

Sequences:

>Translated_410_residues
MPDVIPVTPDSIDKVLADLPRLPRLALGFGSRLRKGTLDVTLPDGRIVRLGGVEPGPAAAMILANYGFASGIINGGDIGI
AEAYLNGDWDTPDLTQFLYLFCVNQHLLQSMLADKPLIRLAQLVRHWFNRNTKRQAKRNIYAHYDIGNSFYSAWLDPSMT
YSSALFEEHTTDLTAAQANKYKRLAEAIDLKPGQKLLEIGCGWGGFAEYVAKTFNAKVVGLTISEQQRDFAQRRIHEAGL
AEKVEIRLQDYRDERDRYDRIASIEMIEAVGEEFWPKYFSQLRDRLLPGGLAGVQAITIQDSLFHHYRREVDFIQRYVFP
GGMLPTPQILKSLGERFGIPVIRERIFGEDYAKTLAIWRNNFRAAWPDLTPAGFDERFRRLWEYYLSYCEAGFLSGNIDV
RQVVFAKSGA
>Mature_409_residues
PDVIPVTPDSIDKVLADLPRLPRLALGFGSRLRKGTLDVTLPDGRIVRLGGVEPGPAAAMILANYGFASGIINGGDIGIA
EAYLNGDWDTPDLTQFLYLFCVNQHLLQSMLADKPLIRLAQLVRHWFNRNTKRQAKRNIYAHYDIGNSFYSAWLDPSMTY
SSALFEEHTTDLTAAQANKYKRLAEAIDLKPGQKLLEIGCGWGGFAEYVAKTFNAKVVGLTISEQQRDFAQRRIHEAGLA
EKVEIRLQDYRDERDRYDRIASIEMIEAVGEEFWPKYFSQLRDRLLPGGLAGVQAITIQDSLFHHYRREVDFIQRYVFPG
GMLPTPQILKSLGERFGIPVIRERIFGEDYAKTLAIWRNNFRAAWPDLTPAGFDERFRRLWEYYLSYCEAGFLSGNIDVR
QVVFAKSGA

Specific function: Transfers a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge [H]

COG id: COG2230

COG function: function code M; Cyclopropane fatty acid synthase and related methyltransferases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CFA/CMAS family [H]

Homologues:

Organism=Escherichia coli, GI1787951, Length=382, Percent_Identity=35.8638743455497, Blast_Score=202, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI133904226, Length=364, Percent_Identity=36.2637362637363, Blast_Score=236, Evalue=2e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003333 [H]

Pfam domain/function: PF02353 CMAS [H]

EC number: =2.1.1.79 [H]

Molecular weight: Translated: 46538; Mature: 46407

Theoretical pI: Translated: 7.62; Mature: 7.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDVIPVTPDSIDKVLADLPRLPRLALGFGSRLRKGTLDVTLPDGRIVRLGGVEPGPAAA
CCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEECCCCEEEEECCCCCCCHHH
MILANYGFASGIINGGDIGIAEAYLNGDWDTPDLTQFLYLFCVNQHLLQSMLADKPLIRL
HHHHHCCHHHCCCCCCCCCHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
AQLVRHWFNRNTKRQAKRNIYAHYDIGNSFYSAWLDPSMTYSSALFEEHTTDLTAAQANK
HHHHHHHHCCCHHHHHHHCCEEEEECCHHHHHHHCCCCHHHHHHHHHHHHCHHHHHHHHH
YKRLAEAIDLKPGQKLLEIGCGWGGFAEYVAKTFNAKVVGLTISEQQRDFAQRRIHEAGL
HHHHHHHHCCCCCHHHHHHCCCCCHHHHHHHHHHCCEEEEEEECHHHHHHHHHHHHHHCC
AEKVEIRLQDYRDERDRYDRIASIEMIEAVGEEFWPKYFSQLRDRLLPGGLAGVQAITIQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHH
DSLFHHYRREVDFIQRYVFPGGMLPTPQILKSLGERFGIPVIRERIFGEDYAKTLAIWRN
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHC
NFRAAWPDLTPAGFDERFRRLWEYYLSYCEAGFLSGNIDVRQVVFAKSGA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEEEECCCC
>Mature Secondary Structure 
PDVIPVTPDSIDKVLADLPRLPRLALGFGSRLRKGTLDVTLPDGRIVRLGGVEPGPAAA
CCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEECCCCEEEEECCCCCCCHHH
MILANYGFASGIINGGDIGIAEAYLNGDWDTPDLTQFLYLFCVNQHLLQSMLADKPLIRL
HHHHHCCHHHCCCCCCCCCHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
AQLVRHWFNRNTKRQAKRNIYAHYDIGNSFYSAWLDPSMTYSSALFEEHTTDLTAAQANK
HHHHHHHHCCCHHHHHHHCCEEEEECCHHHHHHHCCCCHHHHHHHHHHHHCHHHHHHHHH
YKRLAEAIDLKPGQKLLEIGCGWGGFAEYVAKTFNAKVVGLTISEQQRDFAQRRIHEAGL
HHHHHHHHCCCCCHHHHHHCCCCCHHHHHHHHHHCCEEEEEEECHHHHHHHHHHHHHHCC
AEKVEIRLQDYRDERDRYDRIASIEMIEAVGEEFWPKYFSQLRDRLLPGGLAGVQAITIQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHH
DSLFHHYRREVDFIQRYVFPGGMLPTPQILKSLGERFGIPVIRERIFGEDYAKTLAIWRN
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHC
NFRAAWPDLTPAGFDERFRRLWEYYLSYCEAGFLSGNIDVRQVVFAKSGA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]