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The map label for this gene is arpC [H]

Identifier: 146340842

GI number: 146340842

Start: 4081207

End: 4082730

Strand: Reverse

Name: arpC [H]

Synonym: BRADO3905

Alternate gene names: 146340842

Gene position: 4082730-4081207 (Counterclockwise)

Preceding gene: 146340847

Following gene: 146340841

Centisome position: 54.75

GC content: 67.45

Gene sequence:

>1524_bases
GTGTCCACAGTGGGAATTGCCGTCGACGAGCCTTGCCGCGCGTCCGCTGACACGCGGACCGTCGCCGGCAAGCGGGCGCC
TCATGCGCAGCTCAGCCTGCGACATTTCGCCCGCTGGATCGCGGCCATCGGTCTGGCCGCGAGCTCCGCCGGCTGCCTCT
TGACGCAGGATATTCCCGATCCGGCCCTCGATCTGCCCAGGCGCTACAAGTCCGCCTCCGGCGCCGACACGACGGCGCCG
CCGACGCTGGACTGGTGGCGAGGCTTCGGCTCGCGTGAGCTGACCCAGCTGATGGAGGAGGCGCAGAGCGTCAACCTCGA
CATCGCTGCGGCCGTGGCAAGGTTCAGGCAGGCCGACGCGCTGGCGCGTCAGGCGGGAGCCGCGTTGCTGCCGAGCCTGT
CGGGGACGGGGCAGGAGACCTACTCGCGCACGTCAGGCTCGAGCGCGAGCGGGCTCACCAATGGGGGCCGAGAGACCGTC
AATTATCAGGCGTCGCTCTCGGCAAGCTATCAGCTCGACTTCTTCGGCCAGAACCGCGATGCGCTGCAGGCCGCCGAGGA
GACTGCGGTCGCCAACCGTTTCGACCGCGACGTCACCCAGCTGACGACGCTCGCAACCGTCGCCAATGCCTACTTCCAGG
TGCTTGCGGCGCAGGACCGGATTCGCACCGCCGAGCGCAACATCGCCAGCGCCTCGCGCGTGCTCGACGCCATCCGCGAG
CGGCAGAAGGCCGGCACCGGCAATGATCTCGACGTCGCCCAGCAGGAGAGCGTGCTCGCCAACCAGAAGGCCGCGGTGCC
GCCGTTGCGCCAGACGCTCGATCAGAACGTCAATGCGCTCGCCGTGCTGGTCTCCCGGTCGCCCGAGGGCATTCGTATCA
GCGGTGGCTCGCTCGATCAGATCAGGACCCCGCGCGTCACGCCCGGGCTGCCGTCGGAGCTGTTGACGCAGCGGCCGGAC
ATCCGTCGCCAGGAGGCGCAGCTGGCCTCCGCCACGGCCAATGTCGGCAGCGCCCGGGCGCAGTTCTTCCCGAGCATCCA
GCTGACCGGCAATGGCGGCTACCAGAGCGCCGCGCTCGTCTCGCTGTTTCAGCCGCATGCAGCCTTCTTCAGCCTGGCCG
GCAGCCTGACGCAGCCGATCTTCGACGGCGGCAAGATCCTCGGCAATTTCGAGAATGCCAAGGCACGCCAGGATGAACTG
CTGCAGACCTATCGCAAGACGGTCATTCAGGCGTTCACCGACGTCAACAACGCGCTGTTCTCGATCAAGCAGACCACGAT
CCGCCTGCAATTGCAGCGCGAGGTCGTCGCCGCGTCTCGCCGGGCCTTCCAGCTCTCCGAGCAGCAATTGCGCGCGGGAA
CTGCCGATATCGTGACTGTCTTGAATACCCAATTGACGCTGTTTCAGGCCGAGGACGCGCTATGGCAGGCGCAGCTGGCA
CGTCTGCAGGCGTTCGTGAGCCTGTACCAGGCGCTCGGCGGCGGCTGGGAGCCGCGCATGGAGAAGTCGGCCGATGCTCT
TTAA

Upstream 100 bases:

>100_bases
TCTGAGCCGTCGCTGCCGGGGGACGGGGCGGGTGCAGGGCTGTCCGCCGCCTTGGCGGCCGGCTAGAATGATTCCCAAGC
TACAGGGAAGCATCACGCCA

Downstream 100 bases:

>100_bases
ACCGGACGAGAAGGGAGCAGGGGCCGTGAAGCGGGCGCGCTCGAGCGTCGCCCGGCGGCTAGTGTCGATCACGATCACGC
TGCTGATCCTCGGAGGCCTC

Product: multidrug efflux system outer membrane subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 507; Mature: 506

Protein sequence:

>507_residues
MSTVGIAVDEPCRASADTRTVAGKRAPHAQLSLRHFARWIAAIGLAASSAGCLLTQDIPDPALDLPRRYKSASGADTTAP
PTLDWWRGFGSRELTQLMEEAQSVNLDIAAAVARFRQADALARQAGAALLPSLSGTGQETYSRTSGSSASGLTNGGRETV
NYQASLSASYQLDFFGQNRDALQAAEETAVANRFDRDVTQLTTLATVANAYFQVLAAQDRIRTAERNIASASRVLDAIRE
RQKAGTGNDLDVAQQESVLANQKAAVPPLRQTLDQNVNALAVLVSRSPEGIRISGGSLDQIRTPRVTPGLPSELLTQRPD
IRRQEAQLASATANVGSARAQFFPSIQLTGNGGYQSAALVSLFQPHAAFFSLAGSLTQPIFDGGKILGNFENAKARQDEL
LQTYRKTVIQAFTDVNNALFSIKQTTIRLQLQREVVAASRRAFQLSEQQLRAGTADIVTVLNTQLTLFQAEDALWQAQLA
RLQAFVSLYQALGGGWEPRMEKSADAL

Sequences:

>Translated_507_residues
MSTVGIAVDEPCRASADTRTVAGKRAPHAQLSLRHFARWIAAIGLAASSAGCLLTQDIPDPALDLPRRYKSASGADTTAP
PTLDWWRGFGSRELTQLMEEAQSVNLDIAAAVARFRQADALARQAGAALLPSLSGTGQETYSRTSGSSASGLTNGGRETV
NYQASLSASYQLDFFGQNRDALQAAEETAVANRFDRDVTQLTTLATVANAYFQVLAAQDRIRTAERNIASASRVLDAIRE
RQKAGTGNDLDVAQQESVLANQKAAVPPLRQTLDQNVNALAVLVSRSPEGIRISGGSLDQIRTPRVTPGLPSELLTQRPD
IRRQEAQLASATANVGSARAQFFPSIQLTGNGGYQSAALVSLFQPHAAFFSLAGSLTQPIFDGGKILGNFENAKARQDEL
LQTYRKTVIQAFTDVNNALFSIKQTTIRLQLQREVVAASRRAFQLSEQQLRAGTADIVTVLNTQLTLFQAEDALWQAQLA
RLQAFVSLYQALGGGWEPRMEKSADAL
>Mature_506_residues
STVGIAVDEPCRASADTRTVAGKRAPHAQLSLRHFARWIAAIGLAASSAGCLLTQDIPDPALDLPRRYKSASGADTTAPP
TLDWWRGFGSRELTQLMEEAQSVNLDIAAAVARFRQADALARQAGAALLPSLSGTGQETYSRTSGSSASGLTNGGRETVN
YQASLSASYQLDFFGQNRDALQAAEETAVANRFDRDVTQLTTLATVANAYFQVLAAQDRIRTAERNIASASRVLDAIRER
QKAGTGNDLDVAQQESVLANQKAAVPPLRQTLDQNVNALAVLVSRSPEGIRISGGSLDQIRTPRVTPGLPSELLTQRPDI
RRQEAQLASATANVGSARAQFFPSIQLTGNGGYQSAALVSLFQPHAAFFSLAGSLTQPIFDGGKILGNFENAKARQDELL
QTYRKTVIQAFTDVNNALFSIKQTTIRLQLQREVVAASRRAFQLSEQQLRAGTADIVTVLNTQLTLFQAEDALWQAQLAR
LQAFVSLYQALGGGWEPRMEKSADAL

Specific function: The outer membrane component of an antibiotic efflux pump. Confers resistance to numerous structurally unrelated antibiotics such as carbenicillin, chloramphenicol, erythromycin, novobiocin, streptomycin and tetracycline. Is not involved in organic solven

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786785, Length=457, Percent_Identity=28.2275711159737, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI2367348, Length=483, Percent_Identity=24.0165631469979, Blast_Score=91, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 54558; Mature: 54427

Theoretical pI: Translated: 9.01; Mature: 9.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTVGIAVDEPCRASADTRTVAGKRAPHAQLSLRHFARWIAAIGLAASSAGCLLTQDIPD
CCCCCCEECCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCC
PALDLPRRYKSASGADTTAPPTLDWWRGFGSRELTQLMEEAQSVNLDIAAAVARFRQADA
CHHHHHHHHCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LARQAGAALLPSLSGTGQETYSRTSGSSASGLTNGGRETVNYQASLSASYQLDFFGQNRD
HHHHHCHHHCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCEEEEEECCCCHH
ALQAAEETAVANRFDRDVTQLTTLATVANAYFQVLAAQDRIRTAERNIASASRVLDAIRE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RQKAGTGNDLDVAQQESVLANQKAAVPPLRQTLDQNVNALAVLVSRSPEGIRISGGSLDQ
HHHCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHCCCCEEEEEEECCCCCEEECCCCHHH
IRTPRVTPGLPSELLTQRPDIRRQEAQLASATANVGSARAQFFPSIQLTGNGGYQSAALV
CCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHCCCEEEECCCCCHHHHHH
SLFQPHAAFFSLAGSLTQPIFDGGKILGNFENAKARQDELLQTYRKTVIQAFTDVNNALF
HHHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SIKQTTIRLQLQREVVAASRRAFQLSEQQLRAGTADIVTVLNTQLTLFQAEDALWQAQLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCEEEEEHHHHHHHHHHH
RLQAFVSLYQALGGGWEPRMEKSADAL
HHHHHHHHHHHHCCCCCCCHHHCCCCC
>Mature Secondary Structure 
STVGIAVDEPCRASADTRTVAGKRAPHAQLSLRHFARWIAAIGLAASSAGCLLTQDIPD
CCCCCEECCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCC
PALDLPRRYKSASGADTTAPPTLDWWRGFGSRELTQLMEEAQSVNLDIAAAVARFRQADA
CHHHHHHHHCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LARQAGAALLPSLSGTGQETYSRTSGSSASGLTNGGRETVNYQASLSASYQLDFFGQNRD
HHHHHCHHHCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCEEEEEECCCCHH
ALQAAEETAVANRFDRDVTQLTTLATVANAYFQVLAAQDRIRTAERNIASASRVLDAIRE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RQKAGTGNDLDVAQQESVLANQKAAVPPLRQTLDQNVNALAVLVSRSPEGIRISGGSLDQ
HHHCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHCCCCEEEEEEECCCCCEEECCCCHHH
IRTPRVTPGLPSELLTQRPDIRRQEAQLASATANVGSARAQFFPSIQLTGNGGYQSAALV
CCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHCCCEEEECCCCCHHHHHH
SLFQPHAAFFSLAGSLTQPIFDGGKILGNFENAKARQDELLQTYRKTVIQAFTDVNNALF
HHHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SIKQTTIRLQLQREVVAASRRAFQLSEQQLRAGTADIVTVLNTQLTLFQAEDALWQAQLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCEEEEEHHHHHHHHHHH
RLQAFVSLYQALGGGWEPRMEKSADAL
HHHHHHHHHHHHCCCCCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11160799 [H]