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The map label for this gene is mdtA [H]

Identifier: 146340841

GI number: 146340841

Start: 4079814

End: 4081217

Strand: Reverse

Name: mdtA [H]

Synonym: BRADO3904

Alternate gene names: 146340841

Gene position: 4081217-4079814 (Counterclockwise)

Preceding gene: 146340842

Following gene: 146340840

Centisome position: 54.73

GC content: 66.95

Gene sequence:

>1404_bases
ATGCTCTTTAAACCGGACGAGAAGGGAGCAGGGGCCGTGAAGCGGGCGCGCTCGAGCGTCGCCCGGCGGCTAGTGTCGAT
CACGATCACGCTGCTGATCCTCGGAGGCCTCGGCTATATCGGCTGGTCGGCGATGCAGCAGAAGCAGCAGGCCAATAACC
GCTTTGCGCGGCCCGACCTGCCGGTCCCCGTTCTCGCAGCATCGCCCGTCATCAAGGACGTGCCGGTCTATCTCGACGGC
GTCGGCTCGGTGCGTGCGCTGAACACGGTGACGGTGCGGTCGCAGGTCGACGGCAAGCTGATCGCGGTCAATTTCGTCGA
GGGGCAGGACGTCAAGAAAGGCGATGTGCTCGCCGAGATCGATCCGGCGATCTATCAGGCGCAATACGACCAGGCGGTTG
CCAAGAAGGCGCAGGACGAGGCGCAGCTCGCCAACCAGAAGCTCGATCTCGCCCGCTATGAGCAGCTCGCCGCAAGCAGT
GCTGGCTCCAAGCAACAGGCCGATACGCAGCGCGCGGTCGTCGCGCAGCAACAGGCGCTGATCAAGGCCGACCAGGCCGC
CATCGACAATGCCGCGGCGACCTTGAGCTACACCAAGATCGTGGCGCCGATCGCGGGGCGCGCCGGCCTGCGTCAGGTCG
ATCAGGGCAACATCATCCACTCCGCCGACACGACCGGCCTCGTCGTCATCACCCAGTTGCAGCCGATCGCGGTCCAGTTC
AGCCTGCCGCAGCAGCAGATCATGCGGGTCAATGCCGCCGCCGCCAAGGGACCGCTCGCGGTCGACGTGTTCGGCAATGA
CGGTGTCACGGTGATCGATACCGGCACGTTGCGCGGCATCGACAACCAGGTCGACCAGACCACCGGTACGTTGAAGCTGA
AGGCGGAGTTTCCCAACACCAAGTTCCAGCTCTGGCCCGGCCAGTTCGTCAATGTCCGCCTCAAGGTCGAGACGCTGAGG
CAGGCGCTGACGGTGCCGACCTCGGCCGTGCAGCGGGGACCTGCGGGCACTTTCAGCTACGTGATCGGCGAGGGCGATAT
CGCGTCGGCGCATCCGGTGACGGTGGTGCAGCAGAACGAAAGCGAGGCGGTGATCGCGAGCGGCTTGAGCCCGTCCGATC
GCGTCATCACGACCGGCTTCGCCAATCTCGCCGATGGCGCCAAGGTCGTGGTCGGCCGCGCCGACCAGGCGCCGCAGGCC
GATCTCGCGCCGCGCAAGCGCGGCCGCAACCCGCAAGGCAAGGATCAAACAAAGGACCAGGCGAAGGAAGGCGGTGCACC
GGCTGAAGGTGCGCCGAAGGACGGCGAGCGTCGCCGGCGACCGGCCGCCGATGGCCAGGGCGATGCCGGCAACCCGCCTC
AGGGAAGTGGCGAGCAGGGGCGTGGCGCGAGGCCGCAGCCATGA

Upstream 100 bases:

>100_bases
GACGCGCTATGGCAGGCGCAGCTGGCACGTCTGCAGGCGTTCGTGAGCCTGTACCAGGCGCTCGGCGGCGGCTGGGAGCC
GCGCATGGAGAAGTCGGCCG

Downstream 100 bases:

>100_bases
CGCGATCGACAGAGTGAGGGGCTTGTCGCGATGAGCGTCTCCGAACCCTTCATCCGCCGCCCGATCGCAACCTCGCTGCT
CGGCGTCGCGCTCTTGATCG

Product: multidrug ABC transporter

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 467; Mature: 467

Protein sequence:

>467_residues
MLFKPDEKGAGAVKRARSSVARRLVSITITLLILGGLGYIGWSAMQQKQQANNRFARPDLPVPVLAASPVIKDVPVYLDG
VGSVRALNTVTVRSQVDGKLIAVNFVEGQDVKKGDVLAEIDPAIYQAQYDQAVAKKAQDEAQLANQKLDLARYEQLAASS
AGSKQQADTQRAVVAQQQALIKADQAAIDNAAATLSYTKIVAPIAGRAGLRQVDQGNIIHSADTTGLVVITQLQPIAVQF
SLPQQQIMRVNAAAAKGPLAVDVFGNDGVTVIDTGTLRGIDNQVDQTTGTLKLKAEFPNTKFQLWPGQFVNVRLKVETLR
QALTVPTSAVQRGPAGTFSYVIGEGDIASAHPVTVVQQNESEAVIASGLSPSDRVITTGFANLADGAKVVVGRADQAPQA
DLAPRKRGRNPQGKDQTKDQAKEGGAPAEGAPKDGERRRRPAADGQGDAGNPPQGSGEQGRGARPQP

Sequences:

>Translated_467_residues
MLFKPDEKGAGAVKRARSSVARRLVSITITLLILGGLGYIGWSAMQQKQQANNRFARPDLPVPVLAASPVIKDVPVYLDG
VGSVRALNTVTVRSQVDGKLIAVNFVEGQDVKKGDVLAEIDPAIYQAQYDQAVAKKAQDEAQLANQKLDLARYEQLAASS
AGSKQQADTQRAVVAQQQALIKADQAAIDNAAATLSYTKIVAPIAGRAGLRQVDQGNIIHSADTTGLVVITQLQPIAVQF
SLPQQQIMRVNAAAAKGPLAVDVFGNDGVTVIDTGTLRGIDNQVDQTTGTLKLKAEFPNTKFQLWPGQFVNVRLKVETLR
QALTVPTSAVQRGPAGTFSYVIGEGDIASAHPVTVVQQNESEAVIASGLSPSDRVITTGFANLADGAKVVVGRADQAPQA
DLAPRKRGRNPQGKDQTKDQAKEGGAPAEGAPKDGERRRRPAADGQGDAGNPPQGSGEQGRGARPQP
>Mature_467_residues
MLFKPDEKGAGAVKRARSSVARRLVSITITLLILGGLGYIGWSAMQQKQQANNRFARPDLPVPVLAASPVIKDVPVYLDG
VGSVRALNTVTVRSQVDGKLIAVNFVEGQDVKKGDVLAEIDPAIYQAQYDQAVAKKAQDEAQLANQKLDLARYEQLAASS
AGSKQQADTQRAVVAQQQALIKADQAAIDNAAATLSYTKIVAPIAGRAGLRQVDQGNIIHSADTTGLVVITQLQPIAVQF
SLPQQQIMRVNAAAAKGPLAVDVFGNDGVTVIDTGTLRGIDNQVDQTTGTLKLKAEFPNTKFQLWPGQFVNVRLKVETLR
QALTVPTSAVQRGPAGTFSYVIGEGDIASAHPVTVVQQNESEAVIASGLSPSDRVITTGFANLADGAKVVVGRADQAPQA
DLAPRKRGRNPQGKDQTKDQAKEGGAPAEGAPKDGERRRRPAADGQGDAGNPPQGSGEQGRGARPQP

Specific function: Unknown

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=363, Percent_Identity=45.1790633608815, Blast_Score=290, Evalue=1e-79,
Organism=Escherichia coli, GI1786668, Length=378, Percent_Identity=31.7460317460317, Blast_Score=159, Evalue=5e-40,
Organism=Escherichia coli, GI1789665, Length=316, Percent_Identity=33.8607594936709, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI1789929, Length=379, Percent_Identity=28.7598944591029, Blast_Score=132, Evalue=5e-32,
Organism=Escherichia coli, GI87081796, Length=324, Percent_Identity=27.1604938271605, Blast_Score=70, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 49195; Mature: 49195

Theoretical pI: Translated: 10.04; Mature: 10.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFKPDEKGAGAVKRARSSVARRLVSITITLLILGGLGYIGWSAMQQKQQANNRFARPDL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PVPVLAASPVIKDVPVYLDGVGSVRALNTVTVRSQVDGKLIAVNFVEGQDVKKGDVLAEI
CCCCEECCCCHHCCCEEEECCCCEEEEEEEEEEECCCCEEEEEEEECCCCCCCCCEEECC
DPAIYQAQYDQAVAKKAQDEAQLANQKLDLARYEQLAASSAGSKQQADTQRAVVAQQQAL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
IKADQAAIDNAAATLSYTKIVAPIAGRAGLRQVDQGNIIHSADTTGLVVITQLQPIAVQF
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCEEEEEECCCEEEEE
SLPQQQIMRVNAAAAKGPLAVDVFGNDGVTVIDTGTLRGIDNQVDQTTGTLKLKAEFPNT
CCCHHHHHHHHHHHCCCCEEEEEECCCCEEEEECCCCCCCCCHHHCCCCEEEEEEECCCC
KFQLWPGQFVNVRLKVETLRQALTVPTSAVQRGPAGTFSYVIGEGDIASAHPVTVVQQNE
EEEECCCCEEEEEEEHHHHHHHHCCCHHHHHCCCCCCEEEEEECCCCCCCCCEEEEECCC
SEAVIASGLSPSDRVITTGFANLADGAKVVVGRADQAPQADLAPRKRGRNPQGKDQTKDQ
CCEEEECCCCCCCCEEEECCHHHCCCCEEEEECCCCCCCCCCCHHHCCCCCCCCCCCHHH
AKEGGAPAEGAPKDGERRRRPAADGQGDAGNPPQGSGEQGRGARPQP
HHHCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLFKPDEKGAGAVKRARSSVARRLVSITITLLILGGLGYIGWSAMQQKQQANNRFARPDL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PVPVLAASPVIKDVPVYLDGVGSVRALNTVTVRSQVDGKLIAVNFVEGQDVKKGDVLAEI
CCCCEECCCCHHCCCEEEECCCCEEEEEEEEEEECCCCEEEEEEEECCCCCCCCCEEECC
DPAIYQAQYDQAVAKKAQDEAQLANQKLDLARYEQLAASSAGSKQQADTQRAVVAQQQAL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
IKADQAAIDNAAATLSYTKIVAPIAGRAGLRQVDQGNIIHSADTTGLVVITQLQPIAVQF
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCEEEEEECCCEEEEE
SLPQQQIMRVNAAAAKGPLAVDVFGNDGVTVIDTGTLRGIDNQVDQTTGTLKLKAEFPNT
CCCHHHHHHHHHHHCCCCEEEEEECCCCEEEEECCCCCCCCCHHHCCCCEEEEEEECCCC
KFQLWPGQFVNVRLKVETLRQALTVPTSAVQRGPAGTFSYVIGEGDIASAHPVTVVQQNE
EEEECCCCEEEEEEEHHHHHHHHCCCHHHHHCCCCCCEEEEEECCCCCCCCCEEEEECCC
SEAVIASGLSPSDRVITTGFANLADGAKVVVGRADQAPQADLAPRKRGRNPQGKDQTKDQ
CCEEEECCCCCCCCEEEECCHHHCCCCEEEEECCCCCCCCCCCHHHCCCCCCCCCCCHHH
AKEGGAPAEGAPKDGERRRRPAADGQGDAGNPPQGSGEQGRGARPQP
HHHCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA