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The map label for this gene is siaP [H]

Identifier: 146340777

GI number: 146340777

Start: 4007719

End: 4008714

Strand: Reverse

Name: siaP [H]

Synonym: BRADO3835

Alternate gene names: 146340777

Gene position: 4008714-4007719 (Counterclockwise)

Preceding gene: 146340779

Following gene: 146340776

Centisome position: 53.76

GC content: 63.76

Gene sequence:

>996_bases
TTGAAGGCCAGTGCGGCTTCGGCCGTCCTGGGTGGGATCGCGGCCCCGCATGTCGCGCGCGCGCAGAGCGCCGAATTCAC
CTACAAATATGCCAACAACCTGCCGGACACGCATCCGCTGAACGTCCGCGCCAAGGAGATGGCGGCGGCGATCAAGGCCG
AGACCAACGGCAAGTTCGACCTGCAGATCTTCCCGAACAACCAGCTCGGCTCCGACACCGACATGCTGAGCCAGATCCGC
TCGGGCGGCGTCGAGTTCTTCACGCTGTCGGGCCTGATTCTCGCAACCCTGGTTCCAGCAGCGTCGATCAATGGCATCGG
TTTCGCGTTCCCGGACTACGACACGGTCTGGAAGGCCATGGACGGCGATCTCGGCGCTTATGTGCGCGGACAGATCACCA
AGTCCGGCCTGATGGTCATGGACAAGATCTGGGACAACGGCTTCCGCCAGACGACGTCCTCGACGAAGCCGATCAACGGC
CCGGACGATCTCAAGGGCTTCAAGATCCGGGTGCCGGTGTCGCCGCTCTGGACCTCGATGTTCAAGGCGTTCGAGGCGGC
GCCCGCCTCGATCAATTTCAGCGAGGTCTATTCGGCGCTGCAGACCAAGGTCGTCGAGGGCCAGGAAAACCCGCTGGCGA
TCATCTCGACGGCGAAGCTGTACGAGGTGCAGAAGTACTGCTCGCTCACCAACCACATGTGGGACGGCTTCTGGTTCCTG
GCCAACCGCCGCGCCTGGGAGGCCGTGCCGGCCGACATGCGTGCGATTGTCGCCAAGCACATCAACGCCGCCGCCGTGAA
GGAGCGCGAGGACGTCGCCAAGCTCAATGCGGGCCTGCAGCAGGATCTCGCGACCAAGGGCCTGACGTTCAATCAGCCCA
ATGTCGCGCCGTTCCGCGACAAGCTGCGGACCGCCGGCTTCTACGCCGAGTGGAAGGGCAAGTATGGCGATGAGGCCTGG
GCGCTGCTCGAAAAGGCCGTCGGCAAGCTGTCGTAA

Upstream 100 bases:

>100_bases
GATGTCGCTGGATTCGTCCGCGACGTCATCCGGCGCAACGATGCAACAAGAAGAAGCTTCTCAGGGAGAAACGAGAATGA
GCCTGTCACGACGCGCGCTG

Downstream 100 bases:

>100_bases
GTGCAGGGGCGTCGTAGGCGCGTTCAGGTGACGTCATGGCGCATGCCGAGTTCACGGAAATAGCCATCAGCGAGGTGGTC
ATCGAGACCCCTCGCCGTTG

Product: putative TRAP-type C4-dicarboxylate transport system binding periplasmic protein DctP

Products: NA

Alternate protein names: Extracytoplasmic solute receptor protein siaP; N-acetylneuraminic-binding protein; Neu5Ac-binding protein [H]

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MKASAASAVLGGIAAPHVARAQSAEFTYKYANNLPDTHPLNVRAKEMAAAIKAETNGKFDLQIFPNNQLGSDTDMLSQIR
SGGVEFFTLSGLILATLVPAASINGIGFAFPDYDTVWKAMDGDLGAYVRGQITKSGLMVMDKIWDNGFRQTTSSTKPING
PDDLKGFKIRVPVSPLWTSMFKAFEAAPASINFSEVYSALQTKVVEGQENPLAIISTAKLYEVQKYCSLTNHMWDGFWFL
ANRRAWEAVPADMRAIVAKHINAAAVKEREDVAKLNAGLQQDLATKGLTFNQPNVAPFRDKLRTAGFYAEWKGKYGDEAW
ALLEKAVGKLS

Sequences:

>Translated_331_residues
MKASAASAVLGGIAAPHVARAQSAEFTYKYANNLPDTHPLNVRAKEMAAAIKAETNGKFDLQIFPNNQLGSDTDMLSQIR
SGGVEFFTLSGLILATLVPAASINGIGFAFPDYDTVWKAMDGDLGAYVRGQITKSGLMVMDKIWDNGFRQTTSSTKPING
PDDLKGFKIRVPVSPLWTSMFKAFEAAPASINFSEVYSALQTKVVEGQENPLAIISTAKLYEVQKYCSLTNHMWDGFWFL
ANRRAWEAVPADMRAIVAKHINAAAVKEREDVAKLNAGLQQDLATKGLTFNQPNVAPFRDKLRTAGFYAEWKGKYGDEAW
ALLEKAVGKLS
>Mature_331_residues
MKASAASAVLGGIAAPHVARAQSAEFTYKYANNLPDTHPLNVRAKEMAAAIKAETNGKFDLQIFPNNQLGSDTDMLSQIR
SGGVEFFTLSGLILATLVPAASINGIGFAFPDYDTVWKAMDGDLGAYVRGQITKSGLMVMDKIWDNGFRQTTSSTKPING
PDDLKGFKIRVPVSPLWTSMFKAFEAAPASINFSEVYSALQTKVVEGQENPLAIISTAKLYEVQKYCSLTNHMWDGFWFL
ANRRAWEAVPADMRAIVAKHINAAAVKEREDVAKLNAGLQQDLATKGLTFNQPNVAPFRDKLRTAGFYAEWKGKYGDEAW
ALLEKAVGKLS

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid. This protein specifically binds sialic acid [H]

COG id: COG1638

COG function: function code G; TRAP-type C4-dicarboxylate transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 7 family [H]

Homologues:

Organism=Escherichia coli, GI1790004, Length=265, Percent_Identity=30.9433962264151, Blast_Score=143, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018389
- InterPro:   IPR004682 [H]

Pfam domain/function: PF03480 SBP_bac_7 [H]

EC number: NA

Molecular weight: Translated: 36166; Mature: 36166

Theoretical pI: Translated: 9.14; Mature: 9.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKASAASAVLGGIAAPHVARAQSAEFTYKYANNLPDTHPLNVRAKEMAAAIKAETNGKFD
CCCCHHHHHHHHHCCCHHHHCCCCCEEEHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEEE
LQIFPNNQLGSDTDMLSQIRSGGVEFFTLSGLILATLVPAASINGIGFAFPDYDTVWKAM
EEECCCCCCCCHHHHHHHHHHCCCEEEEHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHH
DGDLGAYVRGQITKSGLMVMDKIWDNGFRQTTSSTKPINGPDDLKGFKIRVPVSPLWTSM
CCCCCCCEECEECCCCHHHHHHHHCCCHHHCCCCCCCCCCCCCCCCEEEEECCCHHHHHH
FKAFEAAPASINFSEVYSALQTKVVEGQENPLAIISTAKLYEVQKYCSLTNHMWDGFWFL
HHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCEEEE
ANRRAWEAVPADMRAIVAKHINAAAVKEREDVAKLNAGLQQDLATKGLTFNQPNVAPFRD
ECCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCHHHH
KLRTAGFYAEWKGKYGDEAWALLEKAVGKLS
HHHHCCCEEEECCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKASAASAVLGGIAAPHVARAQSAEFTYKYANNLPDTHPLNVRAKEMAAAIKAETNGKFD
CCCCHHHHHHHHHCCCHHHHCCCCCEEEHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEEE
LQIFPNNQLGSDTDMLSQIRSGGVEFFTLSGLILATLVPAASINGIGFAFPDYDTVWKAM
EEECCCCCCCCHHHHHHHHHHCCCEEEEHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHH
DGDLGAYVRGQITKSGLMVMDKIWDNGFRQTTSSTKPINGPDDLKGFKIRVPVSPLWTSM
CCCCCCCEECEECCCCHHHHHHHHCCCHHHCCCCCCCCCCCCCCCCEEEEECCCHHHHHH
FKAFEAAPASINFSEVYSALQTKVVEGQENPLAIISTAKLYEVQKYCSLTNHMWDGFWFL
HHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCEEEE
ANRRAWEAVPADMRAIVAKHINAAAVKEREDVAKLNAGLQQDLATKGLTFNQPNVAPFRD
ECCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCHHHH
KLRTAGFYAEWKGKYGDEAWALLEKAVGKLS
HHHHCCCEEEECCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA