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The map label for this gene is siaT [H]

Identifier: 146340776

GI number: 146340776

Start: 4005797

End: 4007683

Strand: Reverse

Name: siaT [H]

Synonym: BRADO3834

Alternate gene names: 146340776

Gene position: 4007683-4005797 (Counterclockwise)

Preceding gene: 146340777

Following gene: 146340775

Centisome position: 53.75

GC content: 66.67

Gene sequence:

>1887_bases
ATGGCGCATGCCGAGTTCACGGAAATAGCCATCAGCGAGGTGGTCATCGAGACCCCTCGCCGTTGGTCCTGGCTTCTCCG
CCTGGAGGCCCTGCTCGGCCTCCTGGTCGAGATTCCGGCCGCGCTGCTGGTGTTAGCCGAGATCGTCATCCTGTTCGCCG
GTGTCGTCGCGCGCTACGGCCTGCACCGGCCGCTGATCTGGTCGGACGAGCTCGCCTCGATCCTGTTCCTGTGGCTCGCG
ATGCTCGGCGCCGCTGTGGCCTTTCGCCGTGGCGAGCACATGCGGATGACGGCGATGGTGGCGCGCGCGAGCCCGGGTTT
TCGCGCCTATCTCGATCTGGTCGCCACGACGGCCGCGCTGGCGTTCCTGCTGATGATCGCCTTGCCGTCGTGGGAGTACG
CTTACGAGGAAAGCTATATCACCACGCCTGCGCTGCAGATCTCCAACATCTGTCGCGCGGCCGCATTGCCCGTCGGCATC
GGGCTGATGGCGATGTTCGCCCTGATGCGCTTGGCGCGCGCCGGCAATCTTAGAACGCTGTTGCTCGCAGCTGCCACTGT
CGCTGTCATTCTGGCGCTGTTCTGGGTGGCGCAGCCGATGCTGAAGCCGCTCGGCAATCTCAACCTCGTGATCTTCTTCG
TCGGCGTCGTCGGCTTGTGCGTGTTCGCTGGCGTCCCGATCGCGTTTGCCTTTGGCCTCGCGATCTTCGGCTATCTGGCG
CTGACCACGCGCACACCGCTGATGGTGCTCGTCGGGCGCATGGACGAGGGCATGAGTCACCTCATCCTGCTTTCGGTACC
GCTGTTCGTCTTCTTAGGCCTGCTGATCGAGATGACCGGTATGGCGCGCGCCATGGTCGCCTTCCTGGCAAGTCTGCTCG
GCCACGTCAGAGGCGGCCTGCACTACGTGCTGGTCGGCGCCATGTATCTCGTCTCCGGCATCTCCGGCGCCAAGGCGGCC
GACATGGCCGCGGTCGCGCCGGTGCTGTTTCCCGAGATGAAGGCGCGCGGCGCCAAGCCCGGCGATCTCGTCGCCCTGCT
CGCCGCCACCGGCGCGCAGACCGAGACCATTCCGCCGAGCCTGGTGCTGATCACGATCGGCTCCGTGACGGGCGTGTCGA
TCGCGGCGCTGTTCACCGGCGGCCTGCTGCCGGGCGTGGTGCTCGCGGTCACGCTATGCACGCTGGTGTGGTGGCGCTAT
CGCGGCGAGGACATGAGCGGTGTCCGCCGCGCCACCGGCGCCGAGATCGGCAAGGCGTTCATGGTCTCGGTCCCTGCCCT
GGCCCTGCCCTTCGTGATTCGCGCCGCCGTGGTCGAGGGCATCGCCACCGCGACCGAGGTCTCGACCATCGGCATCGTCT
ATGGCGTCCTCGCCGGCCTCCTGATCTACCGACGCTTCGACTGGCGGCGCCTGATGCCGATGCTGGTCGAGACGGCGGCG
CTGTCCGGCGCCATCCTGCTGATCATCGGCACGGCCACCGGCATGGCCTGGGGGCTCACCCAATCAGGCTTCTCGCGCTC
GCTGGCGGCCGCCATGACCGGGCTGCCGGGCGGGCCTGCGACCTTCATTGCCGTCTCGATCATCGCCTTCACGATCCTTG
GCAGCGTGCTGGAAGGCATTCCGGCGATCGTGCTGTTCGGGCCGCTATTGTTTCCGATCGCGCGAGCCGTCGGCGTGCAC
GAGGTGCATTATGCCATGGTCGTCATCCTGGCGATGGGCATTGGCCTGTTCGCGCCGCCATTCGGGGTCGGATACTACGC
CGCCTGCGCGATCGGCCGGGTCGACCCCGCCGAGGGCATCCGGCCGATCTGGGGCTACCTGCTGGCGCTTCTCATAGGCC
TCATCATCGTTGCGATTTTTCCATGGATTTCGACCGGGTTCCTGTAA

Upstream 100 bases:

>100_bases
GGAAGGGCAAGTATGGCGATGAGGCCTGGGCGCTGCTCGAAAAGGCCGTCGGCAAGCTGTCGTAAGTGCAGGGGCGTCGT
AGGCGCGTTCAGGTGACGTC

Downstream 100 bases:

>100_bases
ACTCTTGAGATGACAAGGGAGGGCAGCCATGAGCACGAACCAGTACCAGCTCGGCCTCGACAAGAACCCCGCCAATTACG
TGCCGCTGACCCCGCTCAGC

Product: TRAP-type C4-dicarboxylate transporter small and large permease

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 628; Mature: 627

Protein sequence:

>628_residues
MAHAEFTEIAISEVVIETPRRWSWLLRLEALLGLLVEIPAALLVLAEIVILFAGVVARYGLHRPLIWSDELASILFLWLA
MLGAAVAFRRGEHMRMTAMVARASPGFRAYLDLVATTAALAFLLMIALPSWEYAYEESYITTPALQISNICRAAALPVGI
GLMAMFALMRLARAGNLRTLLLAAATVAVILALFWVAQPMLKPLGNLNLVIFFVGVVGLCVFAGVPIAFAFGLAIFGYLA
LTTRTPLMVLVGRMDEGMSHLILLSVPLFVFLGLLIEMTGMARAMVAFLASLLGHVRGGLHYVLVGAMYLVSGISGAKAA
DMAAVAPVLFPEMKARGAKPGDLVALLAATGAQTETIPPSLVLITIGSVTGVSIAALFTGGLLPGVVLAVTLCTLVWWRY
RGEDMSGVRRATGAEIGKAFMVSVPALALPFVIRAAVVEGIATATEVSTIGIVYGVLAGLLIYRRFDWRRLMPMLVETAA
LSGAILLIIGTATGMAWGLTQSGFSRSLAAAMTGLPGGPATFIAVSIIAFTILGSVLEGIPAIVLFGPLLFPIARAVGVH
EVHYAMVVILAMGIGLFAPPFGVGYYAACAIGRVDPAEGIRPIWGYLLALLIGLIIVAIFPWISTGFL

Sequences:

>Translated_628_residues
MAHAEFTEIAISEVVIETPRRWSWLLRLEALLGLLVEIPAALLVLAEIVILFAGVVARYGLHRPLIWSDELASILFLWLA
MLGAAVAFRRGEHMRMTAMVARASPGFRAYLDLVATTAALAFLLMIALPSWEYAYEESYITTPALQISNICRAAALPVGI
GLMAMFALMRLARAGNLRTLLLAAATVAVILALFWVAQPMLKPLGNLNLVIFFVGVVGLCVFAGVPIAFAFGLAIFGYLA
LTTRTPLMVLVGRMDEGMSHLILLSVPLFVFLGLLIEMTGMARAMVAFLASLLGHVRGGLHYVLVGAMYLVSGISGAKAA
DMAAVAPVLFPEMKARGAKPGDLVALLAATGAQTETIPPSLVLITIGSVTGVSIAALFTGGLLPGVVLAVTLCTLVWWRY
RGEDMSGVRRATGAEIGKAFMVSVPALALPFVIRAAVVEGIATATEVSTIGIVYGVLAGLLIYRRFDWRRLMPMLVETAA
LSGAILLIIGTATGMAWGLTQSGFSRSLAAAMTGLPGGPATFIAVSIIAFTILGSVLEGIPAIVLFGPLLFPIARAVGVH
EVHYAMVVILAMGIGLFAPPFGVGYYAACAIGRVDPAEGIRPIWGYLLALLIGLIIVAIFPWISTGFL
>Mature_627_residues
AHAEFTEIAISEVVIETPRRWSWLLRLEALLGLLVEIPAALLVLAEIVILFAGVVARYGLHRPLIWSDELASILFLWLAM
LGAAVAFRRGEHMRMTAMVARASPGFRAYLDLVATTAALAFLLMIALPSWEYAYEESYITTPALQISNICRAAALPVGIG
LMAMFALMRLARAGNLRTLLLAAATVAVILALFWVAQPMLKPLGNLNLVIFFVGVVGLCVFAGVPIAFAFGLAIFGYLAL
TTRTPLMVLVGRMDEGMSHLILLSVPLFVFLGLLIEMTGMARAMVAFLASLLGHVRGGLHYVLVGAMYLVSGISGAKAAD
MAAVAPVLFPEMKARGAKPGDLVALLAATGAQTETIPPSLVLITIGSVTGVSIAALFTGGLLPGVVLAVTLCTLVWWRYR
GEDMSGVRRATGAEIGKAFMVSVPALALPFVIRAAVVEGIATATEVSTIGIVYGVLAGLLIYRRFDWRRLMPMLVETAAL
SGAILLIIGTATGMAWGLTQSGFSRSLAAAMTGLPGGPATFIAVSIIAFTILGSVLEGIPAIVLFGPLLFPIARAVGVHE
VHYAMVVILAMGIGLFAPPFGVGYYAACAIGRVDPAEGIRPIWGYLLALLIGLIIVAIFPWISTGFL

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=392, Percent_Identity=26.7857142857143, Blast_Score=131, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 66384; Mature: 66253

Theoretical pI: Translated: 9.02; Mature: 9.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHAEFTEIAISEVVIETPRRWSWLLRLEALLGLLVEIPAALLVLAEIVILFAGVVARYG
CCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LHRPLIWSDELASILFLWLAMLGAAVAFRRGEHMRMTAMVARASPGFRAYLDLVATTAAL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHH
AFLLMIALPSWEYAYEESYITTPALQISNICRAAALPVGIGLMAMFALMRLARAGNLRTL
HHHHHHHCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
LLAAATVAVILALFWVAQPMLKPLGNLNLVIFFVGVVGLCVFAGVPIAFAFGLAIFGYLA
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHH
LTTRTPLMVLVGRMDEGMSHLILLSVPLFVFLGLLIEMTGMARAMVAFLASLLGHVRGGL
HHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
HYVLVGAMYLVSGISGAKAADMAAVAPVLFPEMKARGAKPGDLVALLAATGAQTETIPPS
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCC
LVLITIGSVTGVSIAALFTGGLLPGVVLAVTLCTLVWWRYRGEDMSGVRRATGAEIGKAF
EEEEEECCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
MVSVPALALPFVIRAAVVEGIATATEVSTIGIVYGVLAGLLIYRRFDWRRLMPMLVETAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
LSGAILLIIGTATGMAWGLTQSGFSRSLAAAMTGLPGGPATFIAVSIIAFTILGSVLEGI
HCCEEEEEEECCCCHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
PAIVLFGPLLFPIARAVGVHEVHYAMVVILAMGIGLFAPPFGVGYYAACAIGRVDPAEGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCC
RPIWGYLLALLIGLIIVAIFPWISTGFL
CHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AHAEFTEIAISEVVIETPRRWSWLLRLEALLGLLVEIPAALLVLAEIVILFAGVVARYG
CCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LHRPLIWSDELASILFLWLAMLGAAVAFRRGEHMRMTAMVARASPGFRAYLDLVATTAAL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHH
AFLLMIALPSWEYAYEESYITTPALQISNICRAAALPVGIGLMAMFALMRLARAGNLRTL
HHHHHHHCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
LLAAATVAVILALFWVAQPMLKPLGNLNLVIFFVGVVGLCVFAGVPIAFAFGLAIFGYLA
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHH
LTTRTPLMVLVGRMDEGMSHLILLSVPLFVFLGLLIEMTGMARAMVAFLASLLGHVRGGL
HHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
HYVLVGAMYLVSGISGAKAADMAAVAPVLFPEMKARGAKPGDLVALLAATGAQTETIPPS
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCC
LVLITIGSVTGVSIAALFTGGLLPGVVLAVTLCTLVWWRYRGEDMSGVRRATGAEIGKAF
EEEEEECCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
MVSVPALALPFVIRAAVVEGIATATEVSTIGIVYGVLAGLLIYRRFDWRRLMPMLVETAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
LSGAILLIIGTATGMAWGLTQSGFSRSLAAAMTGLPGGPATFIAVSIIAFTILGSVLEGI
HCCEEEEEEECCCCHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
PAIVLFGPLLFPIARAVGVHEVHYAMVVILAMGIGLFAPPFGVGYYAACAIGRVDPAEGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCC
RPIWGYLLALLIGLIIVAIFPWISTGFL
CHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]