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The map label for this gene is argD [H]

Identifier: 146340734

GI number: 146340734

Start: 3957994

End: 3959190

Strand: Reverse

Name: argD [H]

Synonym: BRADO3787

Alternate gene names: 146340734

Gene position: 3959190-3957994 (Counterclockwise)

Preceding gene: 146340736

Following gene: 146340732

Centisome position: 53.1

GC content: 67.17

Gene sequence:

>1197_bases
ATGCTGACCGCCTCGCATCCGTACGACGCTCTGATGGAGATCACGGCGCGTCCGCGCACCGTCTTCGTCCAGGGCAAGGG
CTCCTGGCTGTGGGACGACGGCGGCAAGCGCTATCTCGACTTCATCCAGGGCTGGGCGGTAAATACGCTCGGCCATGCCC
CGCCCGAGCTAGCCAAGGCGCTCGCGGACCAGGCGGCCCGGCTGATCACACCGAGCCCGGCCTGTTTCAACGACACCAGC
CTGCAACTGGCGAAAGCACTCACCGAGCGCTCCTGCTTCGACCAGGTGTTCTTCGCGAACTCGGGCGCGGAGGCCAATGA
GGGCGCCATCAAGCTGGCGCGCAAGTACGGCGCGCTGCGCAAGAACGGCGCCTATGAGATCATCACCTTCGAGGGCGGCT
TTCATGGCCGGACGCTCGCCACCATGTCAGCCTCCGGCAAGAAGGCGTTCGAGCCGCTGTTCGAGCCGAAGGTGCCGGGC
TTCCCCAAGGCGCGCCTGAACGATATCGCCTCGGTCGAGGCGCTGGTCTCCGACAGCACCGTCGCGATCATGCTGGAGCC
GATCCAGGGCGAAGCCGGCGTGTGGCCGGCGACGGACAAGTTCCTGCAGCAGCTGCAGACGCTCACCACCAGGCACGGCC
TGCTGCTGATCGTCGACGAGATCCAGACCGGGATGGGCCGGACCGGCAAGCTGTTCGGCTATGAGCATGCCGACGTCCTT
CCGGACATCATGACGCTCGGCAAGGGCATCGGCGGCGGCGTCCCGCTCGCCGCCCTGCTCGCGACCAGCGAGGCGTCCTG
CTTCGAGCATGGCGATCAGGGAGGCACCTTCAACGGCAACCCGCTGATGTGTGCGGCCGGCCTCGCCATCCTCGACATCG
TCGCCAAGCCGGAGTTTCTCAAGGCCGTGACCGACAACGGCCTCTATCTGGAAAGCGAGCTGCAGCGTTTGTCGGCGCGG
CACGGCCTGGGCCAGGTGCGCGGTCACGGCCTGCTGCTGGCGCTCGACGTCGTCAGGCCGATCGCTCCCTCGATCGTGGC
GCATGCATTCGAACTCGGCCTGCTCTTGAACGCGCCCCGGCCGGATACGCTGCGCTTCATGCCGGCGCTCAACGTCACGC
GCGACGAGATCGCGGCGATGATCGAGATGCTGGATGGCATCCTGACCAAGACCGGCGCGGCGCGCTGCGTGGCCTGA

Upstream 100 bases:

>100_bases
AAGCTCATCAGCTCCAGGTTTTCGAGAAGGCCGCTCCCGCAAAGGAGCGGCCTTCTCGCTTTTGCGCCCCCACCTTCCCC
TCGAGCACAGGAGACCGACC

Downstream 100 bases:

>100_bases
GCAGGCTGGTCCAAAGCGGCGGTGCCGCGTCAGCCGGGCCGCCCCTCCAGGACGTGGGTGCGGAACGTTTCGAGCAGCTC
GCAGCGGCGCAGCGCGTCGG

Product: acetylornithine transaminase protein

Products: NA

Alternate protein names: ACOAT 2 [H]

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MLTASHPYDALMEITARPRTVFVQGKGSWLWDDGGKRYLDFIQGWAVNTLGHAPPELAKALADQAARLITPSPACFNDTS
LQLAKALTERSCFDQVFFANSGAEANEGAIKLARKYGALRKNGAYEIITFEGGFHGRTLATMSASGKKAFEPLFEPKVPG
FPKARLNDIASVEALVSDSTVAIMLEPIQGEAGVWPATDKFLQQLQTLTTRHGLLLIVDEIQTGMGRTGKLFGYEHADVL
PDIMTLGKGIGGGVPLAALLATSEASCFEHGDQGGTFNGNPLMCAAGLAILDIVAKPEFLKAVTDNGLYLESELQRLSAR
HGLGQVRGHGLLLALDVVRPIAPSIVAHAFELGLLLNAPRPDTLRFMPALNVTRDEIAAMIEMLDGILTKTGAARCVA

Sequences:

>Translated_398_residues
MLTASHPYDALMEITARPRTVFVQGKGSWLWDDGGKRYLDFIQGWAVNTLGHAPPELAKALADQAARLITPSPACFNDTS
LQLAKALTERSCFDQVFFANSGAEANEGAIKLARKYGALRKNGAYEIITFEGGFHGRTLATMSASGKKAFEPLFEPKVPG
FPKARLNDIASVEALVSDSTVAIMLEPIQGEAGVWPATDKFLQQLQTLTTRHGLLLIVDEIQTGMGRTGKLFGYEHADVL
PDIMTLGKGIGGGVPLAALLATSEASCFEHGDQGGTFNGNPLMCAAGLAILDIVAKPEFLKAVTDNGLYLESELQRLSAR
HGLGQVRGHGLLLALDVVRPIAPSIVAHAFELGLLLNAPRPDTLRFMPALNVTRDEIAAMIEMLDGILTKTGAARCVA
>Mature_398_residues
MLTASHPYDALMEITARPRTVFVQGKGSWLWDDGGKRYLDFIQGWAVNTLGHAPPELAKALADQAARLITPSPACFNDTS
LQLAKALTERSCFDQVFFANSGAEANEGAIKLARKYGALRKNGAYEIITFEGGFHGRTLATMSASGKKAFEPLFEPKVPG
FPKARLNDIASVEALVSDSTVAIMLEPIQGEAGVWPATDKFLQQLQTLTTRHGLLLIVDEIQTGMGRTGKLFGYEHADVL
PDIMTLGKGIGGGVPLAALLATSEASCFEHGDQGGTFNGNPLMCAAGLAILDIVAKPEFLKAVTDNGLYLESELQRLSAR
HGLGQVRGHGLLLALDVVRPIAPSIVAHAFELGLLLNAPRPDTLRFMPALNVTRDEIAAMIEMLDGILTKTGAARCVA

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=373, Percent_Identity=34.8525469168901, Blast_Score=206, Evalue=2e-53,
Organism=Homo sapiens, GI13994255, Length=433, Percent_Identity=30.0230946882217, Blast_Score=165, Evalue=6e-41,
Organism=Homo sapiens, GI284507298, Length=297, Percent_Identity=36.3636363636364, Blast_Score=162, Evalue=7e-40,
Organism=Homo sapiens, GI37574042, Length=410, Percent_Identity=28.780487804878, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI24119277, Length=412, Percent_Identity=27.9126213592233, Blast_Score=136, Evalue=4e-32,
Organism=Homo sapiens, GI226442705, Length=410, Percent_Identity=28.0487804878049, Blast_Score=135, Evalue=9e-32,
Organism=Homo sapiens, GI226442709, Length=382, Percent_Identity=28.7958115183246, Blast_Score=128, Evalue=7e-30,
Organism=Homo sapiens, GI188536080, Length=420, Percent_Identity=25.2380952380952, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI38679950, Length=420, Percent_Identity=25.2380952380952, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI38679946, Length=420, Percent_Identity=25.2380952380952, Blast_Score=101, Evalue=1e-21,
Organism=Escherichia coli, GI1788044, Length=362, Percent_Identity=44.7513812154696, Blast_Score=286, Evalue=2e-78,
Organism=Escherichia coli, GI1789759, Length=375, Percent_Identity=39.7333333333333, Blast_Score=262, Evalue=3e-71,
Organism=Escherichia coli, GI145693181, Length=378, Percent_Identity=32.5396825396825, Blast_Score=183, Evalue=2e-47,
Organism=Escherichia coli, GI1789016, Length=399, Percent_Identity=30.5764411027569, Blast_Score=177, Evalue=7e-46,
Organism=Escherichia coli, GI1787560, Length=421, Percent_Identity=31.353919239905, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1786991, Length=375, Percent_Identity=31.2, Blast_Score=134, Evalue=9e-33,
Organism=Escherichia coli, GI1786349, Length=290, Percent_Identity=33.448275862069, Blast_Score=134, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI25144271, Length=375, Percent_Identity=33.3333333333333, Blast_Score=206, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI32564660, Length=423, Percent_Identity=27.4231678486998, Blast_Score=161, Evalue=6e-40,
Organism=Caenorhabditis elegans, GI25144274, Length=285, Percent_Identity=32.280701754386, Blast_Score=147, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI71992977, Length=416, Percent_Identity=29.0865384615385, Blast_Score=139, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI17541228, Length=441, Percent_Identity=26.3038548752834, Blast_Score=105, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI71981843, Length=157, Percent_Identity=33.1210191082803, Blast_Score=89, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6324432, Length=380, Percent_Identity=35, Blast_Score=226, Evalue=4e-60,
Organism=Saccharomyces cerevisiae, GI6323470, Length=391, Percent_Identity=35.8056265984655, Blast_Score=210, Evalue=3e-55,
Organism=Saccharomyces cerevisiae, GI6324386, Length=336, Percent_Identity=27.6785714285714, Blast_Score=108, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6321456, Length=361, Percent_Identity=27.4238227146814, Blast_Score=93, Evalue=7e-20,
Organism=Drosophila melanogaster, GI21357415, Length=370, Percent_Identity=34.5945945945946, Blast_Score=216, Evalue=2e-56,
Organism=Drosophila melanogaster, GI28574759, Length=427, Percent_Identity=28.1030444964871, Blast_Score=146, Evalue=3e-35,
Organism=Drosophila melanogaster, GI161085790, Length=362, Percent_Identity=29.2817679558011, Blast_Score=144, Evalue=8e-35,
Organism=Drosophila melanogaster, GI21356575, Length=351, Percent_Identity=28.4900284900285, Blast_Score=128, Evalue=7e-30,
Organism=Drosophila melanogaster, GI281366494, Length=402, Percent_Identity=22.8855721393035, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24667139, Length=402, Percent_Identity=22.8855721393035, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24667143, Length=402, Percent_Identity=22.8855721393035, Blast_Score=91, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 42548; Mature: 42548

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTASHPYDALMEITARPRTVFVQGKGSWLWDDGGKRYLDFIQGWAVNTLGHAPPELAKA
CCCCCCCHHHHHHHHCCCEEEEEECCCCEEECCCCHHHHHHHHCHHHHCCCCCCHHHHHH
LADQAARLITPSPACFNDTSLQLAKALTERSCFDQVFFANSGAEANEGAIKLARKYGALR
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCHH
KNGAYEIITFEGGFHGRTLATMSASGKKAFEPLFEPKVPGFPKARLNDIASVEALVSDST
CCCCEEEEEECCCCCCCEEEEECCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCE
VAIMLEPIQGEAGVWPATDKFLQQLQTLTTRHGLLLIVDEIQTGMGRTGKLFGYEHADVL
EEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEHHHCCCCCCCCCCCCCHHHHH
PDIMTLGKGIGGGVPLAALLATSEASCFEHGDQGGTFNGNPLMCAAGLAILDIVAKPEFL
HHHHHHCCCCCCCHHHHHHHHHCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHH
KAVTDNGLYLESELQRLSARHGLGQVRGHGLLLALDVVRPIAPSIVAHAFELGLLLNAPR
HHHCCCCEEEHHHHHHHHHHCCCHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHEECCCC
PDTLRFMPALNVTRDEIAAMIEMLDGILTKTGAARCVA
CCCEEECCCCCCCHHHHHHHHHHHHHHHHCCCCHHCCC
>Mature Secondary Structure
MLTASHPYDALMEITARPRTVFVQGKGSWLWDDGGKRYLDFIQGWAVNTLGHAPPELAKA
CCCCCCCHHHHHHHHCCCEEEEEECCCCEEECCCCHHHHHHHHCHHHHCCCCCCHHHHHH
LADQAARLITPSPACFNDTSLQLAKALTERSCFDQVFFANSGAEANEGAIKLARKYGALR
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCHH
KNGAYEIITFEGGFHGRTLATMSASGKKAFEPLFEPKVPGFPKARLNDIASVEALVSDST
CCCCEEEEEECCCCCCCEEEEECCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCE
VAIMLEPIQGEAGVWPATDKFLQQLQTLTTRHGLLLIVDEIQTGMGRTGKLFGYEHADVL
EEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEHHHCCCCCCCCCCCCCHHHHH
PDIMTLGKGIGGGVPLAALLATSEASCFEHGDQGGTFNGNPLMCAAGLAILDIVAKPEFL
HHHHHHCCCCCCCHHHHHHHHHCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHH
KAVTDNGLYLESELQRLSARHGLGQVRGHGLLLALDVVRPIAPSIVAHAFELGLLLNAPR
HHHCCCCEEEHHHHHHHHHHCCCHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHEECCCC
PDTLRFMPALNVTRDEIAAMIEMLDGILTKTGAARCVA
CCCEEECCCCCCCHHHHHHHHHHHHHHHHCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]