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The map label for this gene is aatC [H]

Identifier: 146340528

GI number: 146340528

Start: 3763541

End: 3764761

Strand: Direct

Name: aatC [H]

Synonym: BRADO3571

Alternate gene names: 146340528

Gene position: 3763541-3764761 (Clockwise)

Preceding gene: 146340527

Following gene: 146340529

Centisome position: 50.47

GC content: 65.68

Gene sequence:

>1221_bases
ATGGAAGATTTCTATCGCATCCGCCGTCTGCCGCCTTACGTGTTCGAGCAGGTCAACCGGGCCAAGGCGGCCGCGCGGAA
CGCCGGCGCCGACATCATCGACCTCGGCATGGGCAATCCTGACCTGCCGGCCCCCGCGCATGTGCTGGAGAAGCTCAAGG
AGACCTTGGGCAAGCCGCGCACCGACCGTTACTCGGCGTCGCGCGGCATCGTCGGGCTGCGACGCGCCCAGGCGGCCTAT
TATGACCGCCGCTTCGGGGTGAAGCTCAATCCCGACACTCAGATCGTGGCGACGCTCGGCTCGAAGGAAGGCTTTGCCAA
CGTCGCGCAGGCCATCACCGCGCCGGGCGACGTGATCCTGTGCCCGAACCCGAGCTATCCGATCCACGCCTTCGGCTTCC
TGATGGCGGGCGGCGTGATCCGCTCGGTTCCGGCGGAGCCGACGCCGCAATTCTTCGAAGCGGCCGAGCGGGCGATCATT
CATTCGATCCCGAAGCCGCTGGCGCTGATCGTCTGCTACCCGAGCAATCCGACCGCCTATGTCGCGAGCCTCGACTTCTA
TCGCGACCTCGTCGCATTCGCGAAGAAGCACGAGATCCTGATCCTGTCCGACCTCGCCTACGCCGAGGTCTATTTTGACG
ACAACAATCCGCCGCCGTCGGTGCTGCAGGTGCCGGGCGCGATGGACGTCGCGGTCGAGTTCACCTCGATGTCGAAGACC
TATTCGATGGCCGGCTGGCGCATGGGCTTCGCCGTCGGCAATGAGCGCATCATCGCGGCGCTGGCGCGCGTGAAGTCGTA
TCTCGACTACGGCGCGTTCACGCCGGTTCAGGTAGCAGCGACCGCGGCATTGAACGGCCCGGACGACTGCATCCGGGAGA
TGCGCGACGTCTACCGCAAGCGACGGGACACGCTGGTCGAGTCGTTCGGCCGCGCCGGCTGGGACATCCCGTCGCCGGAA
GCCTCGATGTTTGCCTGGACGCCGCTGCCGGAGAAATTCAAGAGTCTCGGCAGCATGCAGTTCGCGACGCTGATGGTCGA
GAAGTGCGGCGTCGCGGTCTCGCCGGGCGTCGGCTTCGGCGAGCATGGCGAAGGCTATGTCCGCATCGCGATGGTCGAGA
ACGAACAGCGTATCCGGCAGGCTGCGCGCGGCGTCCGCCGCTTCCTTGAAAGCGGCATCGAAACGTTGCACAACGTGGTT
CCTCTCGCCAACCGGCGCTGA

Upstream 100 bases:

>100_bases
CTGTGCTAAGTTTTTGATCTAGCACGGATTACAGGGCAGCGCCGCCGCCGAGCCAGCGCTGCTGGCTGATCCGCCGCCGG
TTGCCGGAGCCGAGAGACCC

Downstream 100 bases:

>100_bases
GTCTCCCGTTGTCCTTGCTGCAGGTTCTTTGATTCCATGGTCGCACCCCTGAGAGTGGGCATCGCGGGCCTCGGCACCGT
GGGTGCCGAGGTCGTTCGTC

Product: aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MEDFYRIRRLPPYVFEQVNRAKAAARNAGADIIDLGMGNPDLPAPAHVLEKLKETLGKPRTDRYSASRGIVGLRRAQAAY
YDRRFGVKLNPDTQIVATLGSKEGFANVAQAITAPGDVILCPNPSYPIHAFGFLMAGGVIRSVPAEPTPQFFEAAERAII
HSIPKPLALIVCYPSNPTAYVASLDFYRDLVAFAKKHEILILSDLAYAEVYFDDNNPPPSVLQVPGAMDVAVEFTSMSKT
YSMAGWRMGFAVGNERIIAALARVKSYLDYGAFTPVQVAATAALNGPDDCIREMRDVYRKRRDTLVESFGRAGWDIPSPE
ASMFAWTPLPEKFKSLGSMQFATLMVEKCGVAVSPGVGFGEHGEGYVRIAMVENEQRIRQAARGVRRFLESGIETLHNVV
PLANRR

Sequences:

>Translated_406_residues
MEDFYRIRRLPPYVFEQVNRAKAAARNAGADIIDLGMGNPDLPAPAHVLEKLKETLGKPRTDRYSASRGIVGLRRAQAAY
YDRRFGVKLNPDTQIVATLGSKEGFANVAQAITAPGDVILCPNPSYPIHAFGFLMAGGVIRSVPAEPTPQFFEAAERAII
HSIPKPLALIVCYPSNPTAYVASLDFYRDLVAFAKKHEILILSDLAYAEVYFDDNNPPPSVLQVPGAMDVAVEFTSMSKT
YSMAGWRMGFAVGNERIIAALARVKSYLDYGAFTPVQVAATAALNGPDDCIREMRDVYRKRRDTLVESFGRAGWDIPSPE
ASMFAWTPLPEKFKSLGSMQFATLMVEKCGVAVSPGVGFGEHGEGYVRIAMVENEQRIRQAARGVRRFLESGIETLHNVV
PLANRR
>Mature_406_residues
MEDFYRIRRLPPYVFEQVNRAKAAARNAGADIIDLGMGNPDLPAPAHVLEKLKETLGKPRTDRYSASRGIVGLRRAQAAY
YDRRFGVKLNPDTQIVATLGSKEGFANVAQAITAPGDVILCPNPSYPIHAFGFLMAGGVIRSVPAEPTPQFFEAAERAII
HSIPKPLALIVCYPSNPTAYVASLDFYRDLVAFAKKHEILILSDLAYAEVYFDDNNPPPSVLQVPGAMDVAVEFTSMSKT
YSMAGWRMGFAVGNERIIAALARVKSYLDYGAFTPVQVAATAALNGPDDCIREMRDVYRKRRDTLVESFGRAGWDIPSPE
ASMFAWTPLPEKFKSLGSMQFATLMVEKCGVAVSPGVGFGEHGEGYVRIAMVENEQRIRQAARGVRRFLESGIETLHNVV
PLANRR

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=391, Percent_Identity=20.9718670076726, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI169881279, Length=391, Percent_Identity=20.9718670076726, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI56713256, Length=302, Percent_Identity=23.5099337748344, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI56713254, Length=302, Percent_Identity=23.5099337748344, Blast_Score=94, Evalue=2e-19,
Organism=Escherichia coli, GI1788722, Length=383, Percent_Identity=49.8694516971279, Blast_Score=409, Evalue=1e-115,
Organism=Escherichia coli, GI1786816, Length=359, Percent_Identity=27.2980501392758, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1788627, Length=267, Percent_Identity=25.8426966292135, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1787710, Length=309, Percent_Identity=24.2718446601942, Blast_Score=69, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71994476, Length=318, Percent_Identity=24.5283018867925, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI71994472, Length=268, Percent_Identity=25.7462686567164, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17567369, Length=427, Percent_Identity=22.9508196721311, Blast_Score=89, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6322401, Length=391, Percent_Identity=21.7391304347826, Blast_Score=97, Evalue=3e-21,
Organism=Drosophila melanogaster, GI28573069, Length=390, Percent_Identity=24.6153846153846, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24646114, Length=390, Percent_Identity=24.6153846153846, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI28573067, Length=390, Percent_Identity=24.6153846153846, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI28573065, Length=390, Percent_Identity=24.6153846153846, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI45551451, Length=376, Percent_Identity=22.6063829787234, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24641770, Length=376, Percent_Identity=22.6063829787234, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24641760, Length=376, Percent_Identity=22.6063829787234, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24641768, Length=376, Percent_Identity=22.6063829787234, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24641766, Length=376, Percent_Identity=22.6063829787234, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24641764, Length=376, Percent_Identity=22.6063829787234, Blast_Score=69, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 44650; Mature: 44650

Theoretical pI: Translated: 8.76; Mature: 8.76

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDFYRIRRLPPYVFEQVNRAKAAARNAGADIIDLGMGNPDLPAPAHVLEKLKETLGKPR
CCHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCCC
TDRYSASRGIVGLRRAQAAYYDRRFGVKLNPDTQIVATLGSKEGFANVAQAITAPGDVIL
CCCHHCCCCCHHHHHHHHHHHHHHCCEEECCCCEEEEECCCCCHHHHHHHHHCCCCCEEE
CPNPSYPIHAFGFLMAGGVIRSVPAEPTPQFFEAAERAIIHSIPKPLALIVCYPSNPTAY
CCCCCCCHHHHHHHHHCCHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEE
VASLDFYRDLVAFAKKHEILILSDLAYAEVYFDDNNPPPSVLQVPGAMDVAVEFTSMSKT
EEHHHHHHHHHHHHCCCCEEEEECCEEEEEEECCCCCCCCEEECCCCCEEEEEEHHHHHH
YSMAGWRMGFAVGNERIIAALARVKSYLDYGAFTPVQVAATAALNGPDDCIREMRDVYRK
HHHCCCEEEHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHH
RRDTLVESFGRAGWDIPSPEASMFAWTPLPEKFKSLGSMQFATLMVEKCGVAVSPGVGFG
HHHHHHHHHCCCCCCCCCCCCCEEEECCCHHHHHHHCCHHHHHHHHHHCCCEECCCCCCC
EHGEGYVRIAMVENEQRIRQAARGVRRFLESGIETLHNVVPLANRR
CCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MEDFYRIRRLPPYVFEQVNRAKAAARNAGADIIDLGMGNPDLPAPAHVLEKLKETLGKPR
CCHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCCC
TDRYSASRGIVGLRRAQAAYYDRRFGVKLNPDTQIVATLGSKEGFANVAQAITAPGDVIL
CCCHHCCCCCHHHHHHHHHHHHHHCCEEECCCCEEEEECCCCCHHHHHHHHHCCCCCEEE
CPNPSYPIHAFGFLMAGGVIRSVPAEPTPQFFEAAERAIIHSIPKPLALIVCYPSNPTAY
CCCCCCCHHHHHHHHHCCHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEE
VASLDFYRDLVAFAKKHEILILSDLAYAEVYFDDNNPPPSVLQVPGAMDVAVEFTSMSKT
EEHHHHHHHHHHHHCCCCEEEEECCEEEEEEECCCCCCCCEEECCCCCEEEEEEHHHHHH
YSMAGWRMGFAVGNERIIAALARVKSYLDYGAFTPVQVAATAALNGPDDCIREMRDVYRK
HHHCCCEEEHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHH
RRDTLVESFGRAGWDIPSPEASMFAWTPLPEKFKSLGSMQFATLMVEKCGVAVSPGVGFG
HHHHHHHHHCCCCCCCCCCCCCEEEECCCHHHHHHHCCHHHHHHHHHHCCCEECCCCCCC
EHGEGYVRIAMVENEQRIRQAARGVRRFLESGIETLHNVVPLANRR
CCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481430; 9734305 [H]