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The map label for this gene is aprE [H]

Identifier: 146340351

GI number: 146340351

Start: 3574106

End: 3575455

Strand: Reverse

Name: aprE [H]

Synonym: BRADO3378

Alternate gene names: 146340351

Gene position: 3575455-3574106 (Counterclockwise)

Preceding gene: 146340352

Following gene: 146340349

Centisome position: 47.95

GC content: 66.3

Gene sequence:

>1350_bases
ATGATGCACGATCTCGCCATCGACACTGTGTTCGGCACGACGAGCACCAGCTCCAGCGTCACGCCCAAGGGTGATTTCCA
CCGCTACGCCATGCTCGGCTACGCCTCGATTGCGCTGGTGTTCGGCGGCTTCGGCGTCTGGGCCGGCTTCGCGCCGCTCG
ACCGCGCGGCGATCGCGCCGGGAACGGTGTCGGTCTCGGGCGACCACAAGGTGGTGCAGCATCGCGAAGGCGGCATCGTC
AGGGAGATCCTCGCCAAGGAAACCAATGCCGTACATCGCGGCGACCTGCTGTTCCGGCTGCAGCCGACCGAGGCACAGGC
CAACACCGACCTGCTGCGCAAGCAGATGGATGCGGCCCTCGCCGAGGAAGCCCGTCTGCTGGCCGAGCGCGGCAATGCGC
GGATGATCACCTTCCCCGACACGCTGCTCAATCGCCAGAACGTGCCGGAGGCGGCGATGGCGATCGCCGACCAGCAGCGG
CTGTTCGTCGAGCGGCGCAACGGCCTGATCAGCCAGATCAACATCCTCAATTCGCAGATCGTCCAGCAGCAGCAGGAGCT
CGCCGGCCGCGACCGCCAGCGCACGGCGCTTGCGGCGCAGCTCGCGAGCTTCGACACGCAGATGAACAACGTCCGCCCGG
CGGTCGCCGCCGGCTATTATCCGCGCAACAAGTTCCTCGAGCTGGAGCGCGACCGCGCCCGTGTCGAGGGTGATCTCGGC
CAGGCCCAGGCCGACGTGGCGCGGCTGACCCAGACCGCGGCGCAGACGCGGCTGCAGATCGATCAGAGCTTGCAGAAATA
TCAGACCGAGGTCGGCCAGCAGCTCGACGCCACCCGCGCCAAGCTGTCCGATCTGCGCGAGAAGATCGTCATCGCCGAGG
ACGTGCTGCGCCGGGTCGACATCTACGCCGAGCGCGACGGCATCGTCATGAACATGAAGGTCCACACCATCGGCGAGGTC
GTGAAGCCCGGCGATACGCTGGCCGAGATCGTCCCGGTCGGCGAAGGCGTCGACGTGATGGCGCATGTCTCGCCGCGCGA
CATCGAGAGCGTCGCGATCGGTCAGAAGGCCGAGGTCCGCTTCGCCAATTTCTCCTCGCGCACGACGCCGGCGATCTTCG
GCAAGGTTGCGAGCGTCTCGGCCGACGCAGTGAGCGACGAGGCCAGCAAGCAGAGCTACTACAAGGCGCGTGTCGTGATC
GACTATTCGACCATCCCGCCCGAGATCGCCGAGAAGATCCTGCCCGGCATGCAGGCGGATGTCATCATCTCCACTGGCGA
GCGCACCGTGCTCGAATATCTGGTCGGCCCGCTGCTCAACACGCTCGCCAAGACGTTCCGCGAAAAATGA

Upstream 100 bases:

>100_bases
CTTCCGGCCCTGCCGAGACATATGTGACGCGCCGCACAGAAGGAGACGTTCAAGTCCCGTTAGATCCAGGGCAGACGATT
TCGGACTCGCAAGGGGGACC

Downstream 100 bases:

>100_bases
GCCAGCAGCTAGCCCGATGCGGCCAGTCCCGCGTCCGCGACCCGCGCAAGGTCGCGGGCGCGCGGCACGCCGATGACGTC
GAATTCGACGTCTTGCTCCG

Product: putative secretion HlyD family protein RTX secretion protein D

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MMHDLAIDTVFGTTSTSSSVTPKGDFHRYAMLGYASIALVFGGFGVWAGFAPLDRAAIAPGTVSVSGDHKVVQHREGGIV
REILAKETNAVHRGDLLFRLQPTEAQANTDLLRKQMDAALAEEARLLAERGNARMITFPDTLLNRQNVPEAAMAIADQQR
LFVERRNGLISQINILNSQIVQQQQELAGRDRQRTALAAQLASFDTQMNNVRPAVAAGYYPRNKFLELERDRARVEGDLG
QAQADVARLTQTAAQTRLQIDQSLQKYQTEVGQQLDATRAKLSDLREKIVIAEDVLRRVDIYAERDGIVMNMKVHTIGEV
VKPGDTLAEIVPVGEGVDVMAHVSPRDIESVAIGQKAEVRFANFSSRTTPAIFGKVASVSADAVSDEASKQSYYKARVVI
DYSTIPPEIAEKILPGMQADVIISTGERTVLEYLVGPLLNTLAKTFREK

Sequences:

>Translated_449_residues
MMHDLAIDTVFGTTSTSSSVTPKGDFHRYAMLGYASIALVFGGFGVWAGFAPLDRAAIAPGTVSVSGDHKVVQHREGGIV
REILAKETNAVHRGDLLFRLQPTEAQANTDLLRKQMDAALAEEARLLAERGNARMITFPDTLLNRQNVPEAAMAIADQQR
LFVERRNGLISQINILNSQIVQQQQELAGRDRQRTALAAQLASFDTQMNNVRPAVAAGYYPRNKFLELERDRARVEGDLG
QAQADVARLTQTAAQTRLQIDQSLQKYQTEVGQQLDATRAKLSDLREKIVIAEDVLRRVDIYAERDGIVMNMKVHTIGEV
VKPGDTLAEIVPVGEGVDVMAHVSPRDIESVAIGQKAEVRFANFSSRTTPAIFGKVASVSADAVSDEASKQSYYKARVVI
DYSTIPPEIAEKILPGMQADVIISTGERTVLEYLVGPLLNTLAKTFREK
>Mature_449_residues
MMHDLAIDTVFGTTSTSSSVTPKGDFHRYAMLGYASIALVFGGFGVWAGFAPLDRAAIAPGTVSVSGDHKVVQHREGGIV
REILAKETNAVHRGDLLFRLQPTEAQANTDLLRKQMDAALAEEARLLAERGNARMITFPDTLLNRQNVPEAAMAIADQQR
LFVERRNGLISQINILNSQIVQQQQELAGRDRQRTALAAQLASFDTQMNNVRPAVAAGYYPRNKFLELERDRARVEGDLG
QAQADVARLTQTAAQTRLQIDQSLQKYQTEVGQQLDATRAKLSDLREKIVIAEDVLRRVDIYAERDGIVMNMKVHTIGEV
VKPGDTLAEIVPVGEGVDVMAHVSPRDIESVAIGQKAEVRFANFSSRTTPAIFGKVASVSADAVSDEASKQSYYKARVVI
DYSTIPPEIAEKILPGMQADVIISTGERTVLEYLVGPLLNTLAKTFREK

Specific function: Involved in the secretion of alkaline protease [H]

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003997
- InterPro:   IPR006143
- InterPro:   IPR006144
- InterPro:   IPR010129 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 49268; Mature: 49268

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS00543 HLYD_FAMILY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMHDLAIDTVFGTTSTSSSVTPKGDFHRYAMLGYASIALVFGGFGVWAGFAPLDRAAIAP
CCCHHEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCC
GTVSVSGDHKVVQHREGGIVREILAKETNAVHRGDLLFRLQPTEAQANTDLLRKQMDAAL
CEEEECCCHHHHHHCCCCHHHHHHHHHCCCEECCCEEEEEECCCCHHHHHHHHHHHHHHH
AEEARLLAERGNARMITFPDTLLNRQNVPEAAMAIADQQRLFVERRNGLISQINILNSQI
HHHHHHHHHCCCEEEEECCHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
VQQQQELAGRDRQRTALAAQLASFDTQMNNVRPAVAAGYYPRNKFLELERDRARVEGDLG
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCHHHHHHHHHHHHCCCCC
QAQADVARLTQTAAQTRLQIDQSLQKYQTEVGQQLDATRAKLSDLREKIVIAEDVLRRVD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IYAERDGIVMNMKVHTIGEVVKPGDTLAEIVPVGEGVDVMAHVSPRDIESVAIGQKAEVR
HHCCCCCEEEEEEEHHHHHHCCCCCHHHHHCCCCCCCEEEEECCCCCHHHHHCCCCCEEE
FANFSSRTTPAIFGKVASVSADAVSDEASKQSYYKARVVIDYSTIPPEIAEKILPGMQAD
EECCCCCCCHHHHHHHHHCCHHHHCCHHHHHHHEEEEEEEEECCCCHHHHHHHCCCCCEE
VIISTGERTVLEYLVGPLLNTLAKTFREK
EEEECCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MMHDLAIDTVFGTTSTSSSVTPKGDFHRYAMLGYASIALVFGGFGVWAGFAPLDRAAIAP
CCCHHEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCC
GTVSVSGDHKVVQHREGGIVREILAKETNAVHRGDLLFRLQPTEAQANTDLLRKQMDAAL
CEEEECCCHHHHHHCCCCHHHHHHHHHCCCEECCCEEEEEECCCCHHHHHHHHHHHHHHH
AEEARLLAERGNARMITFPDTLLNRQNVPEAAMAIADQQRLFVERRNGLISQINILNSQI
HHHHHHHHHCCCEEEEECCHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
VQQQQELAGRDRQRTALAAQLASFDTQMNNVRPAVAAGYYPRNKFLELERDRARVEGDLG
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCHHHHHHHHHHHHCCCCC
QAQADVARLTQTAAQTRLQIDQSLQKYQTEVGQQLDATRAKLSDLREKIVIAEDVLRRVD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IYAERDGIVMNMKVHTIGEVVKPGDTLAEIVPVGEGVDVMAHVSPRDIESVAIGQKAEVR
HHCCCCCEEEEEEEHHHHHHCCCCCHHHHHCCCCCCCEEEEECCCCCHHHHHCCCCCEEE
FANFSSRTTPAIFGKVASVSADAVSDEASKQSYYKARVVIDYSTIPPEIAEKILPGMQAD
EECCCCCCCHHHHHHHHHCCHHHHCCHHHHHHHEEEEEEEEECCCCHHHHHHHCCCCCEE
VIISTGERTVLEYLVGPLLNTLAKTFREK
EEEECCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1427098; 10984043 [H]