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The map label for this gene is ltrA [H]

Identifier: 146340324

GI number: 146340324

Start: 3544290

End: 3545333

Strand: Reverse

Name: ltrA [H]

Synonym: BRADO3350

Alternate gene names: 146340324

Gene position: 3545333-3544290 (Counterclockwise)

Preceding gene: 146340329

Following gene: 146340323

Centisome position: 47.55

GC content: 59.77

Gene sequence:

>1044_bases
ATGCGGCAACATTTGCATCGGGGTGCTGCATCTACGCAGCGCGGAAAATCTGACGAAACGCTTAATGCCTCATGGGAAGA
TTTAAGAGCATTTCTCCTTTGTACGCGGCACCAGAGTTTCAGGAACGCAGCGGAGGTTCTCGGCCTGACGGGTACGACAT
TGATGCGCAAGATCGACCGGCTCGAATACGAGCTCGGATGCAAACTCTTCATCCGCGATCAAACCGGACTATCGCTCAGC
GATGAGGGGCGTGCTCTGCTGTTCGACGTCGAGCAGATGGAACGGCTCAGCTTCAACATTTTCCGGCGCGCCGCGCTCTC
GACCGATACGCGCGGATCGGTGCGCGTGGCCGTGACCGAAGGCCCCGGCAATTTCTGGATCCTGCCGCGACTGATCGACT
TCCAGCGCACCTATCGCAAGATCACGGTCGATCTCAGCTGCGCGATGCAGCAGGCCGACGTTTCGCGGCTCGAGGCCGAT
ATCTCGATTCAGTTCGAACGGCCGACCAACCCGGACGTCATCGTCAGCAAGCTCGGCCGGCTGCACATCTACGGCTTCGT
CTCCGAGGCCTATCGCGATGCTCATGGACTGCCGTCATCGCTGGCCGATCTCAGGAACCATCGTATCATCAAGCAGCACG
GCGTGCAGCTCGACGAGACGGGATATGCGCGCATTCTCGGCCTCGACTCGCTCGAAGGAATCGTCGGCATCTCCACCAAT
TCCAGCGTGGCCGTACTCTACGCCGTCGAACGCAGCGCCGGCATCGGCTTCCTTCCGACCTCGGTGGTCGCGCTGGGAGC
GCCGCTCGTTCCCGTCGATCTCGGCGTCAACTACCACATGGATCTGTGGCTGACCTATCACAAGGAGTTTCGTAACTCCG
ACAGGCACAAGGTGGTGATCGAGTGGCTGAAGCACATTTTCGATGCGAGGATTCATGCCTGCTTCCGCGACGAGTTCATC
CATCCGCTGGACCTGGTGCCGCTCATGGGCAGTTCACAAGACGTCGTCGGCTTCAGCGGCTATGTCGCCCCAAAGCCGGT
CTGA

Upstream 100 bases:

>100_bases
ATGTCGCTCTGAAAAATCAGTGCTTCCTCGCTGCTGTTTCTGCATCTATGTTTCCAGCTTGGCTTTGATGACGTCATCCT
ACTAGTCGGGGCTTGAGTGT

Downstream 100 bases:

>100_bases
TCAGCTATCATATGAGCTAGACGCTCGGGGTTCCCTGATCCGGCAGCAGCCACGGCTGACTGTCGTAGTTCGAGCTGAGC
CGGGCGGTCTCCTGCGGTAT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MRQHLHRGAASTQRGKSDETLNASWEDLRAFLLCTRHQSFRNAAEVLGLTGTTLMRKIDRLEYELGCKLFIRDQTGLSLS
DEGRALLFDVEQMERLSFNIFRRAALSTDTRGSVRVAVTEGPGNFWILPRLIDFQRTYRKITVDLSCAMQQADVSRLEAD
ISIQFERPTNPDVIVSKLGRLHIYGFVSEAYRDAHGLPSSLADLRNHRIIKQHGVQLDETGYARILGLDSLEGIVGISTN
SSVAVLYAVERSAGIGFLPTSVVALGAPLVPVDLGVNYHMDLWLTYHKEFRNSDRHKVVIEWLKHIFDARIHACFRDEFI
HPLDLVPLMGSSQDVVGFSGYVAPKPV

Sequences:

>Translated_347_residues
MRQHLHRGAASTQRGKSDETLNASWEDLRAFLLCTRHQSFRNAAEVLGLTGTTLMRKIDRLEYELGCKLFIRDQTGLSLS
DEGRALLFDVEQMERLSFNIFRRAALSTDTRGSVRVAVTEGPGNFWILPRLIDFQRTYRKITVDLSCAMQQADVSRLEAD
ISIQFERPTNPDVIVSKLGRLHIYGFVSEAYRDAHGLPSSLADLRNHRIIKQHGVQLDETGYARILGLDSLEGIVGISTN
SSVAVLYAVERSAGIGFLPTSVVALGAPLVPVDLGVNYHMDLWLTYHKEFRNSDRHKVVIEWLKHIFDARIHACFRDEFI
HPLDLVPLMGSSQDVVGFSGYVAPKPV
>Mature_347_residues
MRQHLHRGAASTQRGKSDETLNASWEDLRAFLLCTRHQSFRNAAEVLGLTGTTLMRKIDRLEYELGCKLFIRDQTGLSLS
DEGRALLFDVEQMERLSFNIFRRAALSTDTRGSVRVAVTEGPGNFWILPRLIDFQRTYRKITVDLSCAMQQADVSRLEAD
ISIQFERPTNPDVIVSKLGRLHIYGFVSEAYRDAHGLPSSLADLRNHRIIKQHGVQLDETGYARILGLDSLEGIVGISTN
SSVAVLYAVERSAGIGFLPTSVVALGAPLVPVDLGVNYHMDLWLTYHKEFRNSDRHKVVIEWLKHIFDARIHACFRDEFI
HPLDLVPLMGSSQDVVGFSGYVAPKPV

Specific function: Regulatory Protein For The Glycine Cleavage System Operon (Gcv). Mediates Activation Of Gcv By Glycine And Repression By Purines. Gcva Is Negatively Autoregulated. Bind To Three Sites Upstream Of The Gcv Promoter. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789173, Length=240, Percent_Identity=27.9166666666667, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1788706, Length=245, Percent_Identity=24.0816326530612, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI145693193, Length=294, Percent_Identity=25.5102040816327, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 39003; Mature: 39003

Theoretical pI: Translated: 7.42; Mature: 7.42

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQHLHRGAASTQRGKSDETLNASWEDLRAFLLCTRHQSFRNAAEVLGLTGTTLMRKIDR
CCCHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
LEYELGCKLFIRDQTGLSLSDEGRALLFDVEQMERLSFNIFRRAALSTDTRGSVRVAVTE
HHHHCCCEEEEECCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEE
GPGNFWILPRLIDFQRTYRKITVDLSCAMQQADVSRLEADISIQFERPTNPDVIVSKLGR
CCCCEEEEHHHHHHHHHHHEEEEEHHHHHHHHHHHHHCEEEEEEECCCCCHHHHHHHCCC
LHIYGFVSEAYRDAHGLPSSLADLRNHRIIKQHGVQLDETGYARILGLDSLEGIVGISTN
EEEEEEHHHHHHHHCCCCHHHHHHHHCEEHHHHCCEECCCCCEEEEECCCCCCEEEECCC
SSVAVLYAVERSAGIGFLPTSVVALGAPLVPVDLGVNYHMDLWLTYHKEFRNSDRHKVVI
CCEEEEEEEECCCCCCCCHHHHHHHCCCCEEEECCCCEEEEEEEEEEHHHCCCCCHHHHH
EWLKHIFDARIHACFRDEFIHPLDLVPLMGSSQDVVGFSGYVAPKPV
HHHHHHHHHHHHHHHHHCCCCCHHHEECCCCCCCCEEECCCCCCCCC
>Mature Secondary Structure
MRQHLHRGAASTQRGKSDETLNASWEDLRAFLLCTRHQSFRNAAEVLGLTGTTLMRKIDR
CCCHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
LEYELGCKLFIRDQTGLSLSDEGRALLFDVEQMERLSFNIFRRAALSTDTRGSVRVAVTE
HHHHCCCEEEEECCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEE
GPGNFWILPRLIDFQRTYRKITVDLSCAMQQADVSRLEADISIQFERPTNPDVIVSKLGR
CCCCEEEEHHHHHHHHHHHEEEEEHHHHHHHHHHHHHCEEEEEEECCCCCHHHHHHHCCC
LHIYGFVSEAYRDAHGLPSSLADLRNHRIIKQHGVQLDETGYARILGLDSLEGIVGISTN
EEEEEEHHHHHHHHCCCCHHHHHHHHCEEHHHHCCEECCCCCEEEEECCCCCCEEEECCC
SSVAVLYAVERSAGIGFLPTSVVALGAPLVPVDLGVNYHMDLWLTYHKEFRNSDRHKVVI
CCEEEEEEEECCCCCCCCHHHHHHHCCCCEEEECCCCEEEEEEEEEEHHHCCCCCHHHHH
EWLKHIFDARIHACFRDEFIHPLDLVPLMGSSQDVVGFSGYVAPKPV
HHHHHHHHHHHHHHHHHCCCCCHHHEECCCCCCCCEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8748036 [H]