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The map label for this gene is adh [H]

Identifier: 146340298

GI number: 146340298

Start: 3516611

End: 3517669

Strand: Reverse

Name: adh [H]

Synonym: BRADO3321

Alternate gene names: 146340298

Gene position: 3517669-3516611 (Counterclockwise)

Preceding gene: 146340299

Following gene: 146340297

Centisome position: 47.18

GC content: 66.29

Gene sequence:

>1059_bases
ATGGCGTTGATGCGTCGCCAGTCGCTCGTGAAGTTCGATGCACCGCTGTGCGAGACCATCGTCGAGACACCGAAGCCGCA
AGGACGCGAGGTTCTCGTGCGGATCGAGCGCTGCGGCCTGTGCCACTCCGACCTGCACATTCAGGACGGCTATGCCGATC
TCGGCGGCGGCAAGAAGCTCGACACCACGCGCGGCATGACGCTGCCCTTTACACTGGGCCACGAGATCGCCGGCATCGTC
GACGAGGTCGGGCCCGATGTCCCGAAGGAGCTCATCGGCGCCCGCCGCGCGGTGTTTCCGTGGATCGGCTGCGGCCAGTG
CCGCGACTGCGCCAATGGCGACGAGAATTTGTGCGCGAAGCAGCGCTTCCTCGGCGTCTCGATCGACGGCGGCTTCGCCA
CGCACGTGCTGGTGCCCGATGCGAAATACCTGCTCGAATATGATCCGCTGCCGGTGAATCAGGCGGCCACGCTGATGTGC
TCCGGCGTAACCGCCTATGGCGCATTGAAGCGCCTCGTCGACCGGCCGCGCCAGCGCAATCTGCTGCTGATCGGGCTCGG
CGGCGTCGGCATGATGGGCCTGTCGTTTGCCCAGGCGATGTTCAAGCAGCCGATCTCGGTCGCGGATCTCTCGGCGGCCG
CGCGCGACACGGCGCTGCAGAACGGCGCCGCCACCGCCTACGATCCGTCCGAGGCCGACGTGATCAAGCGTATTCTCAAG
GAGACGGGCGGCGGCTTTGACGAGGTCGTCGACTTCGCCGGGAACGAGAAGTCGATGGCCTTTGCGGTCGCCGTCGTCGC
ACGCGGCGGCAAGATCGTCGTCTCCGGACTGATGGGCGGCCAGTTCACGCTGCCGATGGTGCAATGGGTGTACAAGCGCA
TGACCATCGAAGGCTTCATGGTCGGCACGCTCGCCGAAGGTCATGAGCTGATGGCGCTGGCGCGCGCCGGAAAGATCAAG
CCGCCGCCGATGCGCGAGGAGCCGATGGCCGACGTGCAGAAGTGGATCGATGCGCTGCGTGCCGGCCAGGTGGTCGGACG
GGTGGTGCTGACGAACTGA

Upstream 100 bases:

>100_bases
AGACCATTCCGGTGTCCGGCTTTGTTGCCATGGCGCGCGAATTGACCAATAGTCGCAACGACAACACGACCTAACAAGAG
CATTTCAGGGAGATTTCATC

Downstream 100 bases:

>100_bases
TTAGTCCAGTCCTCGAGCATCGCAGGCGGCCGCGGTGCTTGCGCCGCGGCTGACTGCTGCTACTCTGCCCCATCGCTTGA
TACAGGTGGCGACGGGGCCC

Product: zinc-containing alcohol dehydrogenase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 352; Mature: 351

Protein sequence:

>352_residues
MALMRRQSLVKFDAPLCETIVETPKPQGREVLVRIERCGLCHSDLHIQDGYADLGGGKKLDTTRGMTLPFTLGHEIAGIV
DEVGPDVPKELIGARRAVFPWIGCGQCRDCANGDENLCAKQRFLGVSIDGGFATHVLVPDAKYLLEYDPLPVNQAATLMC
SGVTAYGALKRLVDRPRQRNLLLIGLGGVGMMGLSFAQAMFKQPISVADLSAAARDTALQNGAATAYDPSEADVIKRILK
ETGGGFDEVVDFAGNEKSMAFAVAVVARGGKIVVSGLMGGQFTLPMVQWVYKRMTIEGFMVGTLAEGHELMALARAGKIK
PPPMREEPMADVQKWIDALRAGQVVGRVVLTN

Sequences:

>Translated_352_residues
MALMRRQSLVKFDAPLCETIVETPKPQGREVLVRIERCGLCHSDLHIQDGYADLGGGKKLDTTRGMTLPFTLGHEIAGIV
DEVGPDVPKELIGARRAVFPWIGCGQCRDCANGDENLCAKQRFLGVSIDGGFATHVLVPDAKYLLEYDPLPVNQAATLMC
SGVTAYGALKRLVDRPRQRNLLLIGLGGVGMMGLSFAQAMFKQPISVADLSAAARDTALQNGAATAYDPSEADVIKRILK
ETGGGFDEVVDFAGNEKSMAFAVAVVARGGKIVVSGLMGGQFTLPMVQWVYKRMTIEGFMVGTLAEGHELMALARAGKIK
PPPMREEPMADVQKWIDALRAGQVVGRVVLTN
>Mature_351_residues
ALMRRQSLVKFDAPLCETIVETPKPQGREVLVRIERCGLCHSDLHIQDGYADLGGGKKLDTTRGMTLPFTLGHEIAGIVD
EVGPDVPKELIGARRAVFPWIGCGQCRDCANGDENLCAKQRFLGVSIDGGFATHVLVPDAKYLLEYDPLPVNQAATLMCS
GVTAYGALKRLVDRPRQRNLLLIGLGGVGMMGLSFAQAMFKQPISVADLSAAARDTALQNGAATAYDPSEADVIKRILKE
TGGGFDEVVDFAGNEKSMAFAVAVVARGGKIVVSGLMGGQFTLPMVQWVYKRMTIEGFMVGTLAEGHELMALARAGKIKP
PPMREEPMADVQKWIDALRAGQVVGRVVLTN

Specific function: Preferred Specificity Is Towards 1-Propanol. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI71565154, Length=295, Percent_Identity=28.135593220339, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI4501929, Length=266, Percent_Identity=26.3157894736842, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI34577061, Length=266, Percent_Identity=27.0676691729323, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI4501933, Length=278, Percent_Identity=26.6187050359712, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI156627571, Length=279, Percent_Identity=25.089605734767, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI87081918, Length=324, Percent_Identity=33.3333333333333, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI226510992, Length=301, Percent_Identity=29.2358803986711, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI1790045, Length=353, Percent_Identity=24.0793201133144, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1787863, Length=263, Percent_Identity=27.7566539923954, Blast_Score=95, Evalue=8e-21,
Organism=Escherichia coli, GI1788073, Length=279, Percent_Identity=28.3154121863799, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1788407, Length=291, Percent_Identity=25.4295532646048, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1790718, Length=318, Percent_Identity=25.4716981132075, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1786518, Length=303, Percent_Identity=26.7326732673267, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI87082125, Length=263, Percent_Identity=27.7566539923954, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI87082401, Length=334, Percent_Identity=25.4491017964072, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17562584, Length=343, Percent_Identity=30.6122448979592, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17562582, Length=342, Percent_Identity=29.2397660818713, Blast_Score=107, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI71988145, Length=341, Percent_Identity=26.099706744868, Blast_Score=98, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17562876, Length=288, Percent_Identity=25.3472222222222, Blast_Score=88, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI25146526, Length=286, Percent_Identity=24.8251748251748, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17562878, Length=188, Percent_Identity=30.8510638297872, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71997431, Length=288, Percent_Identity=24.3055555555556, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6319621, Length=353, Percent_Identity=27.4787535410765, Blast_Score=114, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6323961, Length=357, Percent_Identity=24.3697478991597, Blast_Score=104, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6324486, Length=334, Percent_Identity=25.748502994012, Blast_Score=103, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6323729, Length=337, Percent_Identity=25.8160237388724, Blast_Score=100, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6320033, Length=384, Percent_Identity=24.4791666666667, Blast_Score=90, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6319258, Length=256, Percent_Identity=26.953125, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6319257, Length=311, Percent_Identity=27.0096463022508, Blast_Score=77, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6323980, Length=338, Percent_Identity=25.4437869822485, Blast_Score=74, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6319955, Length=334, Percent_Identity=23.0538922155689, Blast_Score=64, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6322619, Length=334, Percent_Identity=23.0538922155689, Blast_Score=63, Evalue=6e-11,
Organism=Drosophila melanogaster, GI17137530, Length=280, Percent_Identity=28.2142857142857, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI17737897, Length=281, Percent_Identity=27.7580071174377, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI17737895, Length=295, Percent_Identity=26.4406779661017, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28573965, Length=316, Percent_Identity=23.7341772151899, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24586287, Length=316, Percent_Identity=23.7341772151899, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24586285, Length=316, Percent_Identity=23.7341772151899, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 37842; Mature: 37710

Theoretical pI: Translated: 7.36; Mature: 7.36

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALMRRQSLVKFDAPLCETIVETPKPQGREVLVRIERCGLCHSDLHIQDGYADLGGGKKL
CCCHHHHHHHHCCCHHHHHHHHCCCCCCHHHHEEHHHCCCCCCCCEEECCCHHCCCCCEE
DTTRGMTLPFTLGHEIAGIVDEVGPDVPKELIGARRAVFPWIGCGQCRDCANGDENLCAK
CCCCCCEEEEECCHHHHHHHHHHCCCCCHHHHCCHHHHCCCCCCCCCCCCCCCCHHHHHH
QRFLGVSIDGGFATHVLVPDAKYLLEYDPLPVNQAATLMCSGVTAYGALKRLVDRPRQRN
HHHEEEEECCCEEEEEECCCHHHHEECCCCCCCHHHHHHHCCHHHHHHHHHHHCCCCCCC
LLLIGLGGVGMMGLSFAQAMFKQPISVADLSAAARDTALQNGAATAYDPSEADVIKRILK
EEEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
ETGGGFDEVVDFAGNEKSMAFAVAVVARGGKIVVSGLMGGQFTLPMVQWVYKRMTIEGFM
HHCCCHHHHHHHCCCCCHHHEEEEEHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHEE
VGTLAEGHELMALARAGKIKPPPMREEPMADVQKWIDALRAGQVVGRVVLTN
EEEHHCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCEEEECC
>Mature Secondary Structure 
ALMRRQSLVKFDAPLCETIVETPKPQGREVLVRIERCGLCHSDLHIQDGYADLGGGKKL
CCHHHHHHHHCCCHHHHHHHHCCCCCCHHHHEEHHHCCCCCCCCEEECCCHHCCCCCEE
DTTRGMTLPFTLGHEIAGIVDEVGPDVPKELIGARRAVFPWIGCGQCRDCANGDENLCAK
CCCCCCEEEEECCHHHHHHHHHHCCCCCHHHHCCHHHHCCCCCCCCCCCCCCCCHHHHHH
QRFLGVSIDGGFATHVLVPDAKYLLEYDPLPVNQAATLMCSGVTAYGALKRLVDRPRQRN
HHHEEEEECCCEEEEEECCCHHHHEECCCCCCCHHHHHHHCCHHHHHHHHHHHCCCCCCC
LLLIGLGGVGMMGLSFAQAMFKQPISVADLSAAARDTALQNGAATAYDPSEADVIKRILK
EEEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
ETGGGFDEVVDFAGNEKSMAFAVAVVARGGKIVVSGLMGGQFTLPMVQWVYKRMTIEGFM
HHCCCHHHHHHHCCCCCHHHEEEEEHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHEE
VGTLAEGHELMALARAGKIKPPPMREEPMADVQKWIDALRAGQVVGRVVLTN
EEEHHCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11572479 [H]