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The map label for this gene is alr [H]

Identifier: 146340278

GI number: 146340278

Start: 3495999

End: 3497180

Strand: Reverse

Name: alr [H]

Synonym: BRADO3301

Alternate gene names: 146340278

Gene position: 3497180-3495999 (Counterclockwise)

Preceding gene: 146340279

Following gene: 146340272

Centisome position: 46.9

GC content: 69.12

Gene sequence:

>1182_bases
ATGAGTGTTCCCGAACCGAAACCCGCCGAGCCCTCTGCGTCGGCGGCCGATGCGATCCCCGCCAGCGCGACCGGCGTGCT
GACCATCGATCTCGATGCGCTCGCCGCGAACTGGCGCAAGCTGGAAAAGACCGCGGTGCCGGCCGAATGCGCGGGCGTGA
TCAAGGCCGACGCCTATGGCTGTGGCATTCCGCAGGTAGCGCGCACGCTCGCCGCCGCCGGTTGCAAGACGTTCTTTGTG
GCGACGCTCGGTGAGGCCAAGATCGCCCGCAGCGCCCTGCCCGAGCCAGCCGCGCTCTACGTGCTCGACGGCTTCTTCCA
GAACACCGGCGATGACTACGCTGCGATCAACTGCCGCCCCGTGATCGGCGATCTCAATGAGCTCGCCGAATGGGACATGT
TCTGCCGCCGCACCGGCTGGAAGGGCGGCGCCGCGATCCATGTCGACACCGGCATGAACCGGCTTGGCCTTACGCCGATC
GACGCGCAGGGCATGATCCCGCGCATCCAGAGCGGCGACCATGGCATCACCCTGGTGATGAGCCATCTCGCCTCCGCCGA
GCAGGTCAACAGCCCGGCGAATGCGCGCCAGCTCGCGACCTTCCGCGAGGTCGCCAGCGTCTTCACCGGCGTGCCGGCGG
CGCTCGCCGCCTCCTCCGGCATCTTCCTCGGCGCCTCCTTCCATTTCGACATGGTGCGTCCGGGCGCCGCGCTCTACGGC
GTCAACCCGACACCGGAGGCCGACAACCCGATGCAGCCGGTCGCCGAGATCAAGGCCCGCATCGTGCAGCTGCGGGATCT
CGCTCGCGGTGATGCCGTCGGCTATGGGGGCACCTGGACCGCGCGTCGACCGACGAAGATCGCCATCCTCTCCGCCGGCT
ATGCCGACGGCTATTTCCGCGCCGCCTCGTCCAACGACGGCACCCGCGGCGCCGACGTCATCGTCGCCGGCCAGCGCTGC
CCCGTCGCGGGCCGGGTGTCGATGGACCTGATCGCCGTCGATGTCACCGACCTGCCGCCGAAGGCCGCGCGCCGCGGCCA
TTTCGCCACCCTGCTCGGCGAAGGCATCAGTGTCGACGAGCTCGCGCATCATTTCGGCACCATCGGCTACGAAGTCCTGA
CCAATCTCGGCCGCCGCTACCACCGCATCTACAAGGGCGGCGCGGCGGTTGCGGCGAGCTGA

Upstream 100 bases:

>100_bases
GCGCTTCGGCGACCTCGCCCATGACGGTATGCCGCCGCAGCATCACGACTATTGACCGTGTGCTGTTGAACAGATGCGCC
GCGGCGCGTAAAAGCGCCGC

Downstream 100 bases:

>100_bases
TCGCGAGGCGGCGAGCGCCGGATTCGTTGGCACACTCCGTTGTATCTACATCGTCATTGCGAGCGCAGCGAAGCAATCCA
GAGTCCCGCACACCACCCTG

Product: putative alanine racemase (alr)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 392

Protein sequence:

>393_residues
MSVPEPKPAEPSASAADAIPASATGVLTIDLDALAANWRKLEKTAVPAECAGVIKADAYGCGIPQVARTLAAAGCKTFFV
ATLGEAKIARSALPEPAALYVLDGFFQNTGDDYAAINCRPVIGDLNELAEWDMFCRRTGWKGGAAIHVDTGMNRLGLTPI
DAQGMIPRIQSGDHGITLVMSHLASAEQVNSPANARQLATFREVASVFTGVPAALAASSGIFLGASFHFDMVRPGAALYG
VNPTPEADNPMQPVAEIKARIVQLRDLARGDAVGYGGTWTARRPTKIAILSAGYADGYFRAASSNDGTRGADVIVAGQRC
PVAGRVSMDLIAVDVTDLPPKAARRGHFATLLGEGISVDELAHHFGTIGYEVLTNLGRRYHRIYKGGAAVAAS

Sequences:

>Translated_393_residues
MSVPEPKPAEPSASAADAIPASATGVLTIDLDALAANWRKLEKTAVPAECAGVIKADAYGCGIPQVARTLAAAGCKTFFV
ATLGEAKIARSALPEPAALYVLDGFFQNTGDDYAAINCRPVIGDLNELAEWDMFCRRTGWKGGAAIHVDTGMNRLGLTPI
DAQGMIPRIQSGDHGITLVMSHLASAEQVNSPANARQLATFREVASVFTGVPAALAASSGIFLGASFHFDMVRPGAALYG
VNPTPEADNPMQPVAEIKARIVQLRDLARGDAVGYGGTWTARRPTKIAILSAGYADGYFRAASSNDGTRGADVIVAGQRC
PVAGRVSMDLIAVDVTDLPPKAARRGHFATLLGEGISVDELAHHFGTIGYEVLTNLGRRYHRIYKGGAAVAAS
>Mature_392_residues
SVPEPKPAEPSASAADAIPASATGVLTIDLDALAANWRKLEKTAVPAECAGVIKADAYGCGIPQVARTLAAAGCKTFFVA
TLGEAKIARSALPEPAALYVLDGFFQNTGDDYAAINCRPVIGDLNELAEWDMFCRRTGWKGGAAIHVDTGMNRLGLTPID
AQGMIPRIQSGDHGITLVMSHLASAEQVNSPANARQLATFREVASVFTGVPAALAASSGIFLGASFHFDMVRPGAALYGV
NPTPEADNPMQPVAEIKARIVQLRDLARGDAVGYGGTWTARRPTKIAILSAGYADGYFRAASSNDGTRGADVIVAGQRCP
VAGRVSMDLIAVDVTDLPPKAARRGHFATLLGEGISVDELAHHFGTIGYEVLTNLGRRYHRIYKGGAAVAAS

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1790487, Length=374, Percent_Identity=34.4919786096257, Blast_Score=168, Evalue=5e-43,
Organism=Escherichia coli, GI1787439, Length=367, Percent_Identity=31.6076294277929, Blast_Score=141, Evalue=6e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 41084; Mature: 40953

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVPEPKPAEPSASAADAIPASATGVLTIDLDALAANWRKLEKTAVPAECAGVIKADAYG
CCCCCCCCCCCCCCHHHCCCCCCCEEEEEEHHHHHHHHHHHHHHCCCHHHHHEEEECCCC
CGIPQVARTLAAAGCKTFFVATLGEAKIARSALPEPAALYVLDGFFQNTGDDYAAINCRP
CCHHHHHHHHHHHCHHHEEEECCCHHHHHHHCCCCCEEEEEEEHHHHCCCCCEEEEEEEE
VIGDLNELAEWDMFCRRTGWKGGAAIHVDTGMNRLGLTPIDAQGMIPRIQSGDHGITLVM
CCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
SHLASAEQVNSPANARQLATFREVASVFTGVPAALAASSGIFLGASFHFDMVRPGAALYG
HHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHCCCCEEEEEEEEEEEECCCCEEEC
VNPTPEADNPMQPVAEIKARIVQLRDLARGDAVGYGGTWTARRPTKIAILSAGYADGYFR
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCEEEEEECCCCCCEEE
AASSNDGTRGADVIVAGQRCPVAGRVSMDLIAVDVTDLPPKAARRGHFATLLGEGISVDE
ECCCCCCCCCCEEEEECCCCCCCCCCEEEEEEEEECCCCHHHHHCCCHHHHHCCCCCHHH
LAHHFGTIGYEVLTNLGRRYHRIYKGGAAVAAS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCC
>Mature Secondary Structure 
SVPEPKPAEPSASAADAIPASATGVLTIDLDALAANWRKLEKTAVPAECAGVIKADAYG
CCCCCCCCCCCCCHHHCCCCCCCEEEEEEHHHHHHHHHHHHHHCCCHHHHHEEEECCCC
CGIPQVARTLAAAGCKTFFVATLGEAKIARSALPEPAALYVLDGFFQNTGDDYAAINCRP
CCHHHHHHHHHHHCHHHEEEECCCHHHHHHHCCCCCEEEEEEEHHHHCCCCCEEEEEEEE
VIGDLNELAEWDMFCRRTGWKGGAAIHVDTGMNRLGLTPIDAQGMIPRIQSGDHGITLVM
CCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
SHLASAEQVNSPANARQLATFREVASVFTGVPAALAASSGIFLGASFHFDMVRPGAALYG
HHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHCCCCEEEEEEEEEEEECCCCEEEC
VNPTPEADNPMQPVAEIKARIVQLRDLARGDAVGYGGTWTARRPTKIAILSAGYADGYFR
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCEEEEEECCCCCCEEE
AASSNDGTRGADVIVAGQRCPVAGRVSMDLIAVDVTDLPPKAARRGHFATLLGEGISVDE
ECCCCCCCCCCEEEEECCCCCCCCCCEEEEEEEEECCCCHHHHHCCCHHHHHCCCCCHHH
LAHHFGTIGYEVLTNLGRRYHRIYKGGAAVAAS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA