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The map label for this gene is thcR [H]

Identifier: 146340237

GI number: 146340237

Start: 3460547

End: 3461533

Strand: Reverse

Name: thcR [H]

Synonym: BRADO3256

Alternate gene names: 146340237

Gene position: 3461533-3460547 (Counterclockwise)

Preceding gene: 146340238

Following gene: 146340233

Centisome position: 46.42

GC content: 68.19

Gene sequence:

>987_bases
ATGACGGGCGACATCGGCCTCGAACCGTTGCATCGCCACGCCCTGATCCGAACCTCGAGCGCCGAGGTGCTGCGCGATCT
CGCCAGCCGTAAGCTCGGCGCGGAGCGCGTCGATTTCCGCAATGCCGAACGCTTCGAGGCCATCGTCAACCTGATCGAGC
TGCAGACCATAGGGCTCGCCTTCGGCACCACGACCTGCGACATGGTCTCCGATCATCGGACGGCCGACTTCCTGCGCGTG
CAGATCTCCCTGAGAGGACGCGCCGTGAGCTGCGCCCGCGGCGAGGCGACCGACGTCAATGAGCACCAGTTCGCGGTCGC
GCCGGCCGGCATGCCCTGGCAGATGGCGTGTCAGGGCGGACATCGCCGGCTGACCCTGCGGCTCGATCCGCAGGCACTGC
GACAACGGTTGACCGCGCTGGTCGGCGTGCAGCCGCGCACCGACTACACGATCGAAGCTGCCATCCCCGCAGCGGACCCC
CAGGCCCGCAGCCTGCAGCGGCTGCTCGATTTTCTCATCACCCAGCTGAGCGAGCAGGACGCGGTCTTTCCGGCGGCGGT
CTACCGCGAGCTCGAAGACGCCGTGCACGTGGCCTTTCTCTGCGCCAGCCGGCACCGTTTCCGCGACGCGCTGATCGATC
CCTCGCCGATGCCCGATTTCGGCCTGGTCAAACGGCTCGAGGACTACATCGAGGCCAACTGGCACGAGGCGATCACGATC
GAGCGCCTCGCGGATGAAGCGGGTGTCAGCGCCAGGTCGATCTTTCGCGTCTTCGAGCGCGTGCGCGGCTATTCGCCGAT
GGCCTTCGTCAAGTCCGTGCGCCTGCGCCGGGCGCACGAGATGCTGCGCTCGGGAGATCCGAGCGTGACGGTGGCGGTGG
CAGCGGCCGCCTGCAACTTCGCCAACGCCGGACATTTCGCGCGCTACTACCGCGCCACGTTCGGCGAACTGCCGTCGGCG
ACGATCGCCCGCGCCGAGCGGAGGTGA

Upstream 100 bases:

>100_bases
CAGGTAGCATAGGTTAATTTCGGAGCTCAGGAGCCGCGGCTTGAACCGTCTCTTGACCGCAGCTGACACCGTCAGTGCTG
CACCACGGCCGAGCCCGGCA

Downstream 100 bases:

>100_bases
CCGACGCGCGCATCTCACAGGACCGATTCGAGCGCGCTGCGCAGGCTCTGATGACGAAACACGAAGCCGCTCGACAACGC
CTTGTTCGGCACCACACGCT

Product: AraC/XylS family transcription factor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 328; Mature: 327

Protein sequence:

>328_residues
MTGDIGLEPLHRHALIRTSSAEVLRDLASRKLGAERVDFRNAERFEAIVNLIELQTIGLAFGTTTCDMVSDHRTADFLRV
QISLRGRAVSCARGEATDVNEHQFAVAPAGMPWQMACQGGHRRLTLRLDPQALRQRLTALVGVQPRTDYTIEAAIPAADP
QARSLQRLLDFLITQLSEQDAVFPAAVYRELEDAVHVAFLCASRHRFRDALIDPSPMPDFGLVKRLEDYIEANWHEAITI
ERLADEAGVSARSIFRVFERVRGYSPMAFVKSVRLRRAHEMLRSGDPSVTVAVAAAACNFANAGHFARYYRATFGELPSA
TIARAERR

Sequences:

>Translated_328_residues
MTGDIGLEPLHRHALIRTSSAEVLRDLASRKLGAERVDFRNAERFEAIVNLIELQTIGLAFGTTTCDMVSDHRTADFLRV
QISLRGRAVSCARGEATDVNEHQFAVAPAGMPWQMACQGGHRRLTLRLDPQALRQRLTALVGVQPRTDYTIEAAIPAADP
QARSLQRLLDFLITQLSEQDAVFPAAVYRELEDAVHVAFLCASRHRFRDALIDPSPMPDFGLVKRLEDYIEANWHEAITI
ERLADEAGVSARSIFRVFERVRGYSPMAFVKSVRLRRAHEMLRSGDPSVTVAVAAAACNFANAGHFARYYRATFGELPSA
TIARAERR
>Mature_327_residues
TGDIGLEPLHRHALIRTSSAEVLRDLASRKLGAERVDFRNAERFEAIVNLIELQTIGLAFGTTTCDMVSDHRTADFLRVQ
ISLRGRAVSCARGEATDVNEHQFAVAPAGMPWQMACQGGHRRLTLRLDPQALRQRLTALVGVQPRTDYTIEAAIPAADPQ
ARSLQRLLDFLITQLSEQDAVFPAAVYRELEDAVHVAFLCASRHRFRDALIDPSPMPDFGLVKRLEDYIEANWHEAITIE
RLADEAGVSARSIFRVFERVRGYSPMAFVKSVRLRRAHEMLRSGDPSVTVAVAAAACNFANAGHFARYYRATFGELPSAT
IARAERR

Specific function: Probably involved in the positive regulation of the thc operon for the degradation of the thiocarbamate herbicide EPTC [H]

COG id: COG2207

COG function: function code K; AraC-type DNA-binding domain-containing proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018062
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 36552; Mature: 36421

Theoretical pI: Translated: 8.24; Mature: 8.24

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGDIGLEPLHRHALIRTSSAEVLRDLASRKLGAERVDFRNAERFEAIVNLIELQTIGLA
CCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHE
FGTTTCDMVSDHRTADFLRVQISLRGRAVSCARGEATDVNEHQFAVAPAGMPWQMACQGG
ECCCHHHHHHCCCCCEEEEEEEEECCCEEEECCCCCCCCCCCEEEEECCCCCHHHHCCCC
HRRLTLRLDPQALRQRLTALVGVQPRTDYTIEAAIPAADPQARSLQRLLDFLITQLSEQD
CEEEEEEECHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCC
AVFPAAVYRELEDAVHVAFLCASRHRFRDALIDPSPMPDFGLVKRLEDYIEANWHEAITI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHHHH
ERLADEAGVSARSIFRVFERVRGYSPMAFVKSVRLRRAHEMLRSGDPSVTVAVAAAACNF
HHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHCC
ANAGHFARYYRATFGELPSATIARAERR
CCCHHHHHHHHHHHHCCCCHHHHHCCCC
>Mature Secondary Structure 
TGDIGLEPLHRHALIRTSSAEVLRDLASRKLGAERVDFRNAERFEAIVNLIELQTIGLA
CCCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHE
FGTTTCDMVSDHRTADFLRVQISLRGRAVSCARGEATDVNEHQFAVAPAGMPWQMACQGG
ECCCHHHHHHCCCCCEEEEEEEEECCCEEEECCCCCCCCCCCEEEEECCCCCHHHHCCCC
HRRLTLRLDPQALRQRLTALVGVQPRTDYTIEAAIPAADPQARSLQRLLDFLITQLSEQD
CEEEEEEECHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCC
AVFPAAVYRELEDAVHVAFLCASRHRFRDALIDPSPMPDFGLVKRLEDYIEANWHEAITI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHHHH
ERLADEAGVSARSIFRVFERVRGYSPMAFVKSVRLRRAHEMLRSGDPSVTVAVAAAACNF
HHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHCC
ANAGHFARYYRATFGELPSATIARAERR
CCCHHHHHHHHHHHHCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7836301 [H]