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The map label for this gene is ubiE [H]

Identifier: 146340233

GI number: 146340233

Start: 3456889

End: 3457698

Strand: Reverse

Name: ubiE [H]

Synonym: BRADO3252

Alternate gene names: 146340233

Gene position: 3457698-3456889 (Counterclockwise)

Preceding gene: 146340237

Following gene: 146340227

Centisome position: 46.37

GC content: 66.05

Gene sequence:

>810_bases
ATGACGGCATCCGACAAGGCCTTCACCGGTTCGATCCCGCAGATCTACGACGAGCTGCTGGTTCCGCTGATCTTCACGCC
CTATGCACATGATCTTGCAGGCCGTATTGCGAAGGCAAAGCCTGGCCAGGTGCTGGAGACGGCGGCGGGAACCGGCGTCG
TGACCCGGGCGCTTCATGCGGCGCTGCCGCCGGAGGTGCGCATGACGGCCACCGACCTCAACGAACCCATGCTGATGCAG
GCGAGGACCCATCTCGCCGGCGCTGACCGCATCAGCTTCCAACAGGCCGATGCGCTGGCCCTGCCCTTTGCCGATGCGAG
CTTCGATGTCGTCGCGTGCCAGTTCGGCGTGATGTTCTTCCCGGATCGCGTCAAGGGCTATGCCGAGGCGCGCCGCGTGC
TCAGGCCGGGCGGACGCTTCGTCTTTAACGTGTGGGACCGGATCGAGGACAACGAGTTCGCCCACGTGGTGCATGAGACG
CTGCAACAGATCTTCTCAGACAACCCGCCCCAGTTCTTCACCCGCGCGCCGCATGGCTATTTCGATCCGGTGAAGATCCG
GGCCGACCTGGGCGACGCCGGCTTCTCCGATATCATCATCGAGACGCTGCCTCACCGCAGCCGCGCCGCCTCTGCGCAGG
AGCCCGCCATTGCCTACTGCCAGGGTACGCCGATGCGCGGCGAGATCGAGGCGCGGGGCACGCCGGACCTCGCCACCGTG
ACGCAAGCGGCCGCGAACGCGATCCGGCAACGCTTCGGAGATGGACCGGTCGAGGGGCAGATCCAGGGGCTGGTGATTTC
AGCCCGGTGA

Upstream 100 bases:

>100_bases
CGCAGGCCCGATTGGCAAGACGCAGATGAGGGCGCGGACTTCGTCCGCCGACGACCACCGCCCTGACGTTTCTCCGCCAC
ACCTGGAACAGGAGCCAGCC

Downstream 100 bases:

>100_bases
GCGCCGCAGCTAGACCGTCGGCAGGACGGAGAACTCTTCGCCGGGCCGGCGCAGCGCGAGTTGATCGACCGTGGCCGGCG
TGTCCGCGACATTGTCGACG

Product: ubiquinone/menaquinone biosynthesis methyltransferase

Products: S-Adenosyl-L-Homocysteine; @OCTA02.txt*2- Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol!; Menaquinol. [C]

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 268

Protein sequence:

>269_residues
MTASDKAFTGSIPQIYDELLVPLIFTPYAHDLAGRIAKAKPGQVLETAAGTGVVTRALHAALPPEVRMTATDLNEPMLMQ
ARTHLAGADRISFQQADALALPFADASFDVVACQFGVMFFPDRVKGYAEARRVLRPGGRFVFNVWDRIEDNEFAHVVHET
LQQIFSDNPPQFFTRAPHGYFDPVKIRADLGDAGFSDIIIETLPHRSRAASAQEPAIAYCQGTPMRGEIEARGTPDLATV
TQAAANAIRQRFGDGPVEGQIQGLVISAR

Sequences:

>Translated_269_residues
MTASDKAFTGSIPQIYDELLVPLIFTPYAHDLAGRIAKAKPGQVLETAAGTGVVTRALHAALPPEVRMTATDLNEPMLMQ
ARTHLAGADRISFQQADALALPFADASFDVVACQFGVMFFPDRVKGYAEARRVLRPGGRFVFNVWDRIEDNEFAHVVHET
LQQIFSDNPPQFFTRAPHGYFDPVKIRADLGDAGFSDIIIETLPHRSRAASAQEPAIAYCQGTPMRGEIEARGTPDLATV
TQAAANAIRQRFGDGPVEGQIQGLVISAR
>Mature_268_residues
TASDKAFTGSIPQIYDELLVPLIFTPYAHDLAGRIAKAKPGQVLETAAGTGVVTRALHAALPPEVRMTATDLNEPMLMQA
RTHLAGADRISFQQADALALPFADASFDVVACQFGVMFFPDRVKGYAEARRVLRPGGRFVFNVWDRIEDNEFAHVVHETL
QQIFSDNPPQFFTRAPHGYFDPVKIRADLGDAGFSDIIIETLPHRSRAASAQEPAIAYCQGTPMRGEIEARGTPDLATVT
QAAANAIRQRFGDGPVEGQIQGLVISAR

Specific function: Methyltransferase required for the conversion of dimethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiE family [H]

Homologues:

Organism=Escherichia coli, GI48994983, Length=101, Percent_Identity=34.6534653465347, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004033 [H]

Pfam domain/function: PF01209 Ubie_methyltran [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 29275; Mature: 29143

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTASDKAFTGSIPQIYDELLVPLIFTPYAHDLAGRIAKAKPGQVLETAAGTGVVTRALHA
CCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHCCCHHHHHHHHH
ALPPEVRMTATDLNEPMLMQARTHLAGADRISFQQADALALPFADASFDVVACQFGVMFF
HCCCCEEEECCCCCCCHHHHHHHHHCCCCCCCHHCCCEEEEECCCCCCCCEEEHHCCEEC
PDRVKGYAEARRVLRPGGRFVFNVWDRIEDNEFAHVVHETLQQIFSDNPPQFFTRAPHGY
CHHHHHHHHHHHHHCCCCCEEEEHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHCCCCCC
FDPVKIRADLGDAGFSDIIIETLPHRSRAASAQEPAIAYCQGTPMRGEIEARGTPDLATV
CCCEEEEECCCCCCHHHHHHHHCCCCHHHCCCCCCCEEEECCCCCCCEEECCCCCCHHHH
TQAAANAIRQRFGDGPVEGQIQGLVISAR
HHHHHHHHHHHHCCCCCCCEEEEEEEECC
>Mature Secondary Structure 
TASDKAFTGSIPQIYDELLVPLIFTPYAHDLAGRIAKAKPGQVLETAAGTGVVTRALHA
CCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHCCCHHHHHHHHH
ALPPEVRMTATDLNEPMLMQARTHLAGADRISFQQADALALPFADASFDVVACQFGVMFF
HCCCCEEEECCCCCCCHHHHHHHHHCCCCCCCHHCCCEEEEECCCCCCCCEEEHHCCEEC
PDRVKGYAEARRVLRPGGRFVFNVWDRIEDNEFAHVVHETLQQIFSDNPPQFFTRAPHGY
CHHHHHHHHHHHHHCCCCCEEEEHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHCCCCCC
FDPVKIRADLGDAGFSDIIIETLPHRSRAASAQEPAIAYCQGTPMRGEIEARGTPDLATV
CCCEEEEECCCCCCHHHHHHHHCCCCHHHCCCCCCCEEEECCCCCCCEEECCCCCCHHHH
TQAAANAIRQRFGDGPVEGQIQGLVISAR
HHHHHHHHHHHHCCCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; 2-Polyprenyl-6- Methoxy-1,4-Benzoquinol; Demethylmenaquinol [C]

Specific reaction: S-Adenosyl-L-Methionine + @OCTA02.txt*2-Polyprenyl-6- Methoxy-1,4-Benzoquinol! = S-Adenosyl-L-Homocysteine + 2- Polyprenyl-3-Methyl-6-Methoxy -1,4-Benzoquinol S-Adenosyl-L-Methionine + Demethylmenaquinol = S-Adenosyl-L-Homocysteine + Menaquinol. [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA