Click here to switch to the map view.

The map label for this gene is mmgC [H]

Identifier: 146339584

GI number: 146339584

Start: 2755999

End: 2757273

Strand: Direct

Name: mmgC [H]

Synonym: BRADO2575

Alternate gene names: 146339584

Gene position: 2755999-2757273 (Clockwise)

Preceding gene: 146339582

Following gene: 146339587

Centisome position: 36.96

GC content: 63.06

Gene sequence:

>1275_bases
ATGGATTTTTCCTTGCCTAAGGAGCTCACAGCCTATCTTGACGAGCTCGACCGCTTCATCGATGCCGAGATCAAGCCGCT
CGAGGAGGCCGATGACAACATCCGGTTCTTCGACCATCGCCGGGAATGGGCGCGCACCGATTTCGAGAATGGCGGCCTGC
CGCGGCATGAGTGGGAGCAATTGCTGCGTAAAGCCAAGGATCGCGCCGATGCCGCCGGCCATTTGCGCTTCGCGATCCCG
AAACGCTATGGCGGCAAGGACGGCTCGAATCTCTGGATGGCCGTGATCCGCGAGCATTTCGCCTCCAAGGGACTCGGCCT
GCACAACGATTTGCAGAACGAGCATTCGATCGTCGGCAATTTGCCGATCGTCACCATGCTCGACCGCTACGGCCGCGACG
ATCAGAAGGCGATGATCGACGGTTCGATCACCGGCAAGTACCGCATCACGTTTGGGTTGACGGAGCCGCATCACGGCTCT
GACGCGACCCACATGGAGACCAAGGCCGTCCCGGCGACGCGCGACAACGTCAAGGGATGGCTGATCAACGGCGAGAAGAT
GTGGACGACGGGCATGCACGTCGCCACCCACTGCGCGCTGTTCGCGCGCACCTCGGGCAATGACGGCGATGCCCGCGGAA
TCACCTGCTTTCTGGTGCCGGCGAAGAGCGAAGGCGTGAAGGTCGAGGAGTATCTCTGGACCTTCAACATGCCGACCGAC
CATCCCCGTGTCAGCTTCACCGACGTGTTCGTCCCGGAGGATGCGCTGTTCGGCGAGGTCGGCCGCGGGCTGTCGCTGGC
GCAGTGCTTCGTTCACGAGAACCGCATCCGGCAGGCCGCGAGCTCGCTCGGCGCCGCGGTGTTCTGCATCAATGAGAGCG
TGAACTACGCGCGGGAGCGCAAGCCGTTCGGCAAGGCGCTGGCCGAGAACCAGGCGATCCAGTGGCCGCTGGTGGAGCTG
GCGACCCAGGCCGAGATGCTGCGGCTCCTGATCCGCAAGACCGCGTGGGAGATGGATCAGCTGACGCAGGCGCAGGTCGA
GCACACGCTGTCGGACAAGGTCTCGATGTGCAACTACTGGGCTAACCGCCTGTGCTGTGAGGCCGCCGACCGTGCCATTC
AGGTGCATGGCGGCATGGGCTATTCGCGCCATAAGCCGTTCGAGCACATCTACCGCCACCACCGCCGCTACCGCATCACG
GAGGGGAGCGAGGAGATCCAGATGCGCAAGGTGGCGGGGTTCCTGTTTGGATATATGGGAGCGAACAAGAGGTGA

Upstream 100 bases:

>100_bases
CCATCCAAATACGCAACCGCGCTGCGCGCCACAAGCACGCGGCGGAGAGCCGGCCCGACCAAGATCAAGAACAACAACGA
CACGCACAGGGAGACACGCC

Downstream 100 bases:

>100_bases
GGTTGTCGTCGTAGGAAGTTCGTCATTGCGAGGGCCGGCGCAGGAATTCAGACCAGTCACTTGGCCCCTGGATTGCTTCG
GCGCAAGGGCGCCTCGCAAT

Product: putative acyl-CoA dehydrogenase

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 424

Protein sequence:

>424_residues
MDFSLPKELTAYLDELDRFIDAEIKPLEEADDNIRFFDHRREWARTDFENGGLPRHEWEQLLRKAKDRADAAGHLRFAIP
KRYGGKDGSNLWMAVIREHFASKGLGLHNDLQNEHSIVGNLPIVTMLDRYGRDDQKAMIDGSITGKYRITFGLTEPHHGS
DATHMETKAVPATRDNVKGWLINGEKMWTTGMHVATHCALFARTSGNDGDARGITCFLVPAKSEGVKVEEYLWTFNMPTD
HPRVSFTDVFVPEDALFGEVGRGLSLAQCFVHENRIRQAASSLGAAVFCINESVNYARERKPFGKALAENQAIQWPLVEL
ATQAEMLRLLIRKTAWEMDQLTQAQVEHTLSDKVSMCNYWANRLCCEAADRAIQVHGGMGYSRHKPFEHIYRHHRRYRIT
EGSEEIQMRKVAGFLFGYMGANKR

Sequences:

>Translated_424_residues
MDFSLPKELTAYLDELDRFIDAEIKPLEEADDNIRFFDHRREWARTDFENGGLPRHEWEQLLRKAKDRADAAGHLRFAIP
KRYGGKDGSNLWMAVIREHFASKGLGLHNDLQNEHSIVGNLPIVTMLDRYGRDDQKAMIDGSITGKYRITFGLTEPHHGS
DATHMETKAVPATRDNVKGWLINGEKMWTTGMHVATHCALFARTSGNDGDARGITCFLVPAKSEGVKVEEYLWTFNMPTD
HPRVSFTDVFVPEDALFGEVGRGLSLAQCFVHENRIRQAASSLGAAVFCINESVNYARERKPFGKALAENQAIQWPLVEL
ATQAEMLRLLIRKTAWEMDQLTQAQVEHTLSDKVSMCNYWANRLCCEAADRAIQVHGGMGYSRHKPFEHIYRHHRRYRIT
EGSEEIQMRKVAGFLFGYMGANKR
>Mature_424_residues
MDFSLPKELTAYLDELDRFIDAEIKPLEEADDNIRFFDHRREWARTDFENGGLPRHEWEQLLRKAKDRADAAGHLRFAIP
KRYGGKDGSNLWMAVIREHFASKGLGLHNDLQNEHSIVGNLPIVTMLDRYGRDDQKAMIDGSITGKYRITFGLTEPHHGS
DATHMETKAVPATRDNVKGWLINGEKMWTTGMHVATHCALFARTSGNDGDARGITCFLVPAKSEGVKVEEYLWTFNMPTD
HPRVSFTDVFVPEDALFGEVGRGLSLAQCFVHENRIRQAASSLGAAVFCINESVNYARERKPFGKALAENQAIQWPLVEL
ATQAEMLRLLIRKTAWEMDQLTQAQVEHTLSDKVSMCNYWANRLCCEAADRAIQVHGGMGYSRHKPFEHIYRHHRRYRIT
EGSEEIQMRKVAGFLFGYMGANKR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=348, Percent_Identity=30.7471264367816, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI4557231, Length=351, Percent_Identity=31.0541310541311, Blast_Score=132, Evalue=6e-31,
Organism=Homo sapiens, GI187960098, Length=351, Percent_Identity=31.0541310541311, Blast_Score=132, Evalue=8e-31,
Organism=Homo sapiens, GI4501859, Length=348, Percent_Identity=28.1609195402299, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI21361497, Length=411, Percent_Identity=26.7639902676399, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI7656849, Length=361, Percent_Identity=28.5318559556787, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI4501857, Length=387, Percent_Identity=26.8733850129199, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI76496475, Length=422, Percent_Identity=26.0663507109005, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI4557235, Length=422, Percent_Identity=26.0663507109005, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI48976061, Length=294, Percent_Identity=27.5510204081633, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI211971008, Length=294, Percent_Identity=27.5510204081633, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI38505218, Length=307, Percent_Identity=28.0130293159609, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI226958412, Length=406, Percent_Identity=23.6453201970443, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI226958414, Length=349, Percent_Identity=25.214899713467, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI7669494, Length=289, Percent_Identity=27.681660899654, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI4503943, Length=205, Percent_Identity=30.7317073170732, Blast_Score=72, Evalue=7e-13,
Organism=Escherichia coli, GI87081958, Length=417, Percent_Identity=26.1390887290168, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI1786223, Length=336, Percent_Identity=26.7857142857143, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI87081702, Length=263, Percent_Identity=25.4752851711027, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17569725, Length=382, Percent_Identity=29.3193717277487, Blast_Score=139, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI17534899, Length=355, Percent_Identity=30.1408450704225, Blast_Score=136, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17570075, Length=428, Percent_Identity=26.1682242990654, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17508101, Length=412, Percent_Identity=27.1844660194175, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17506239, Length=350, Percent_Identity=26, Blast_Score=119, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI17533517, Length=290, Percent_Identity=30.3448275862069, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI71985184, Length=355, Percent_Identity=27.6056338028169, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17505929, Length=308, Percent_Identity=29.5454545454545, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17551932, Length=304, Percent_Identity=29.2763157894737, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17562446, Length=296, Percent_Identity=26.3513513513513, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17538396, Length=408, Percent_Identity=24.2647058823529, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI71990804, Length=266, Percent_Identity=26.3157894736842, Blast_Score=92, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI32563615, Length=242, Percent_Identity=28.5123966942149, Blast_Score=88, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI71985192, Length=315, Percent_Identity=25.7142857142857, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17534353, Length=274, Percent_Identity=26.6423357664234, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71982178, Length=254, Percent_Identity=26.3779527559055, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24666513, Length=314, Percent_Identity=30.5732484076433, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24660351, Length=343, Percent_Identity=31.4868804664723, Blast_Score=132, Evalue=5e-31,
Organism=Drosophila melanogaster, GI21356377, Length=348, Percent_Identity=29.8850574712644, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24646207, Length=345, Percent_Identity=28.4057971014493, Blast_Score=118, Evalue=7e-27,
Organism=Drosophila melanogaster, GI281363737, Length=425, Percent_Identity=25.6470588235294, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI21355753, Length=396, Percent_Identity=26.5151515151515, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI19920834, Length=221, Percent_Identity=32.579185520362, Blast_Score=86, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 48311; Mature: 48311

Theoretical pI: Translated: 7.17; Mature: 7.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFSLPKELTAYLDELDRFIDAEIKPLEEADDNIRFFDHRREWARTDFENGGLPRHEWEQ
CCCCCHHHHHHHHHHHHHHHCCCCCCHHCCCCCCEEHHHHHHHHHCCCCCCCCCHHHHHH
LLRKAKDRADAAGHLRFAIPKRYGGKDGSNLWMAVIREHFASKGLGLHNDLQNEHSIVGN
HHHHHHHHCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHCCCCHHHHCC
LPIVTMLDRYGRDDQKAMIDGSITGKYRITFGLTEPHHGSDATHMETKAVPATRDNVKGW
CHHHHHHHHHCCCCCCEEECCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEE
LINGEKMWTTGMHVATHCALFARTSGNDGDARGITCFLVPAKSEGVKVEEYLWTFNMPTD
EECCCEEEECHHHHHHHHHHEEECCCCCCCCCCEEEEEEECCCCCCEEEHEEEEECCCCC
HPRVSFTDVFVPEDALFGEVGRGLSLAQCFVHENRIRQAASSLGAAVFCINESVNYARER
CCCEEEEEEECCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEECCHHHHHHC
KPFGKALAENQAIQWPLVELATQAEMLRLLIRKTAWEMDQLTQAQVEHTLSDKVSMCNYW
CHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ANRLCCEAADRAIQVHGGMGYSRHKPFEHIYRHHRRYRITEGSEEIQMRKVAGFLFGYMG
HHHHHHHHHCCEEEEECCCCCCCCCCHHHHHHHHHCEEECCCHHHHHHHHHHHHHHHHCC
ANKR
CCCC
>Mature Secondary Structure
MDFSLPKELTAYLDELDRFIDAEIKPLEEADDNIRFFDHRREWARTDFENGGLPRHEWEQ
CCCCCHHHHHHHHHHHHHHHCCCCCCHHCCCCCCEEHHHHHHHHHCCCCCCCCCHHHHHH
LLRKAKDRADAAGHLRFAIPKRYGGKDGSNLWMAVIREHFASKGLGLHNDLQNEHSIVGN
HHHHHHHHCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHCCCCHHHHCC
LPIVTMLDRYGRDDQKAMIDGSITGKYRITFGLTEPHHGSDATHMETKAVPATRDNVKGW
CHHHHHHHHHCCCCCCEEECCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEE
LINGEKMWTTGMHVATHCALFARTSGNDGDARGITCFLVPAKSEGVKVEEYLWTFNMPTD
EECCCEEEECHHHHHHHHHHEEECCCCCCCCCCEEEEEEECCCCCCEEEHEEEEECCCCC
HPRVSFTDVFVPEDALFGEVGRGLSLAQCFVHENRIRQAASSLGAAVFCINESVNYARER
CCCEEEEEEECCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEECCHHHHHHC
KPFGKALAENQAIQWPLVELATQAEMLRLLIRKTAWEMDQLTQAQVEHTLSDKVSMCNYW
CHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ANRLCCEAADRAIQVHGGMGYSRHKPFEHIYRHHRRYRITEGSEEIQMRKVAGFLFGYMG
HHHHHHHHHCCEEEEECCCCCCCCCCHHHHHHHHHCEEECCCHHHHHHHHHHHHHHHHCC
ANKR
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]