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The map label for this gene is caiD [C]

Identifier: 146339587

GI number: 146339587

Start: 2760133

End: 2760942

Strand: Direct

Name: caiD [C]

Synonym: BRADO2578

Alternate gene names: 146339587

Gene position: 2760133-2760942 (Clockwise)

Preceding gene: 146339584

Following gene: 146339588

Centisome position: 37.02

GC content: 67.04

Gene sequence:

>810_bases
ATGGACAACCGCATCGCGATCGAGATCAAGGACGGCGTCGCCGATGTCCGCCTGGTCCGCGCCGACAAGATGAATGCGCT
CGATCAGGAGATGTTCGCAGCGCTGGTGGCCGCGACCGAACGGCTGTCGAACGAGAAGGGGCTGCGCGCCGTGGTGCTGT
CGGGCGAGGGCCGCGCGTTCTGCGCCGGGCTCGACATGGGCCGCTTCGCCGCGATGAAGGAGTCTGGCGGCAATGGTATC
GCTGGCGGCGAGAAGCGCGACCTCACCGTTCGCACCCACGGCAAGGCCAACTTCGCGCAGCAGGCGGTATGGGGCTGGCG
GCAGCTACCGGTGCCGGTGATTGCTGCGGTGCATGGCGTGGCCTATGGCGGCGGCTTCCAGCTCGCGCTCGGCGCCGATA
TGCGCTACGTCGCACCGGAGACCAAAATGTCGATCATGGAGATCAAATGGGGTCTCGTGCCCGACATGGCCGGCACGCCG
ATCCTGGCGACCTTGATGCGCGACGATATCCTGCGGGAGCTGACCTACACCGGCCGGGTGTTCTCGCCGGAGGAGGGGCA
GGCCTACGGTCTCGTCACCCGAATCTGCCCCGATCCGCGCGCCGCCGCGCTGGAGACGGCGCGGGAGATCGCGGACAAGA
ACCCCGACGCGATCCGCGCGGCCAAGCGGATGCTGAACAATCTTTCCGTTGATCCCGGCCCGGCGCTGCTGGCGGAGTCG
GTAGAGCAGCAGAAGCTGATCGGTAGTCCGAACCAGCTGGAGTCGGTGCGGGCGAACATCGAGAAGCGCGCACCGAAGTT
CGCGGATTAG

Upstream 100 bases:

>100_bases
AAGTTTCCGCCTGACATGTTGTGAGTTAATTGGTCGATTGACTAAATCGCTCCGACAGCCCCATGTAAAGTCACAAAGAC
AATCGTGAGGAGACCGCCCG

Downstream 100 bases:

>100_bases
CACAGTGGTTCCGGGATGCTCCGAAGGAGCAGACCCGGAATCTCGAGATTCCGGGTTCGATGCTGCGCATCGCCCCGGAA
TGACGACGACACTCAAACCG

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MDNRIAIEIKDGVADVRLVRADKMNALDQEMFAALVAATERLSNEKGLRAVVLSGEGRAFCAGLDMGRFAAMKESGGNGI
AGGEKRDLTVRTHGKANFAQQAVWGWRQLPVPVIAAVHGVAYGGGFQLALGADMRYVAPETKMSIMEIKWGLVPDMAGTP
ILATLMRDDILRELTYTGRVFSPEEGQAYGLVTRICPDPRAAALETAREIADKNPDAIRAAKRMLNNLSVDPGPALLAES
VEQQKLIGSPNQLESVRANIEKRAPKFAD

Sequences:

>Translated_269_residues
MDNRIAIEIKDGVADVRLVRADKMNALDQEMFAALVAATERLSNEKGLRAVVLSGEGRAFCAGLDMGRFAAMKESGGNGI
AGGEKRDLTVRTHGKANFAQQAVWGWRQLPVPVIAAVHGVAYGGGFQLALGADMRYVAPETKMSIMEIKWGLVPDMAGTP
ILATLMRDDILRELTYTGRVFSPEEGQAYGLVTRICPDPRAAALETAREIADKNPDAIRAAKRMLNNLSVDPGPALLAES
VEQQKLIGSPNQLESVRANIEKRAPKFAD
>Mature_269_residues
MDNRIAIEIKDGVADVRLVRADKMNALDQEMFAALVAATERLSNEKGLRAVVLSGEGRAFCAGLDMGRFAAMKESGGNGI
AGGEKRDLTVRTHGKANFAQQAVWGWRQLPVPVIAAVHGVAYGGGFQLALGADMRYVAPETKMSIMEIKWGLVPDMAGTP
ILATLMRDDILRELTYTGRVFSPEEGQAYGLVTRICPDPRAAALETAREIADKNPDAIRAAKRMLNNLSVDPGPALLAES
VEQQKLIGSPNQLESVRANIEKRAPKFAD

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI70995211, Length=262, Percent_Identity=29.3893129770992, Blast_Score=98, Evalue=8e-21,
Organism=Homo sapiens, GI194097323, Length=269, Percent_Identity=27.1375464684015, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI4502327, Length=264, Percent_Identity=29.9242424242424, Blast_Score=81, Evalue=9e-16,
Organism=Homo sapiens, GI68989263, Length=221, Percent_Identity=24.4343891402715, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI31542718, Length=258, Percent_Identity=23.6434108527132, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI221142681, Length=253, Percent_Identity=29.6442687747036, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1787659, Length=247, Percent_Identity=26.3157894736842, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1788682, Length=207, Percent_Identity=31.4009661835749, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1787660, Length=267, Percent_Identity=29.2134831460674, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1790281, Length=184, Percent_Identity=26.6304347826087, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17536985, Length=220, Percent_Identity=29.0909090909091, Blast_Score=100, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17540714, Length=237, Percent_Identity=29.1139240506329, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17554946, Length=266, Percent_Identity=28.5714285714286, Blast_Score=91, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI25145438, Length=267, Percent_Identity=27.3408239700375, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17534483, Length=228, Percent_Identity=26.3157894736842, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17558304, Length=209, Percent_Identity=27.2727272727273, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17560910, Length=214, Percent_Identity=25.7009345794392, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17508951, Length=221, Percent_Identity=28.0542986425339, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI25144276, Length=221, Percent_Identity=28.0542986425339, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17508953, Length=221, Percent_Identity=28.0542986425339, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24653139, Length=266, Percent_Identity=29.6992481203008, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI19920382, Length=223, Percent_Identity=30.4932735426009, Blast_Score=95, Evalue=4e-20,
Organism=Drosophila melanogaster, GI20129971, Length=263, Percent_Identity=26.2357414448669, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24653477, Length=263, Percent_Identity=26.2357414448669, Blast_Score=77, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 29029; Mature: 29029

Theoretical pI: Translated: 7.42; Mature: 7.42

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNRIAIEIKDGVADVRLVRADKMNALDQEMFAALVAATERLSNEKGLRAVVLSGEGRAF
CCCEEEEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEE
CAGLDMGRFAAMKESGGNGIAGGEKRDLTVRTHGKANFAQQAVWGWRQLPVPVIAAVHGV
EECCCCHHHHHHHCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHH
AYGGGFQLALGADMRYVAPETKMSIMEIKWGLVPDMAGTPILATLMRDDILRELTYTGRV
EECCCEEEEECCCEEEECCCHHHHHEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCE
FSPEEGQAYGLVTRICPDPRAAALETAREIADKNPDAIRAAKRMLNNLSVDPGPALLAES
ECCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHH
VEQQKLIGSPNQLESVRANIEKRAPKFAD
HHHHHHCCCCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MDNRIAIEIKDGVADVRLVRADKMNALDQEMFAALVAATERLSNEKGLRAVVLSGEGRAF
CCCEEEEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEE
CAGLDMGRFAAMKESGGNGIAGGEKRDLTVRTHGKANFAQQAVWGWRQLPVPVIAAVHGV
EECCCCHHHHHHHCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHH
AYGGGFQLALGADMRYVAPETKMSIMEIKWGLVPDMAGTPILATLMRDDILRELTYTGRV
EECCCEEEEECCCEEEECCCHHHHHEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCE
FSPEEGQAYGLVTRICPDPRAAALETAREIADKNPDAIRAAKRMLNNLSVDPGPALLAES
ECCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHH
VEQQKLIGSPNQLESVRANIEKRAPKFAD
HHHHHHCCCCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA