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The map label for this gene is xylB [H]

Identifier: 146339377

GI number: 146339377

Start: 2514143

End: 2515591

Strand: Direct

Name: xylB [H]

Synonym: BRADO2359

Alternate gene names: 146339377

Gene position: 2514143-2515591 (Clockwise)

Preceding gene: 146339376

Following gene: 146339378

Centisome position: 33.72

GC content: 70.81

Gene sequence:

>1449_bases
GTGTTTCTCGGACTGGATGTCGGCACATCCGGCGTAAAGGCCGTGCTGGAGGACGAGGCGGGCGCGCTGGTCGCGAGCGC
CGGCCGTCCGCTGGCGCTGTCGCATCCGCAGCCTTTGTGGTCCGAGCAGAATCCCGATCATTGGGTCGAGGCCGTCATCG
GCGCGGTCGACGATCTCGCTGCGCGTCATCCGCGCGAGGTTGCGGTGGTGCGCGGCATCGGCCTGTCCGGCCAGATGCAC
GGCGCCACCTTGCTGGGCCGCGACGGCCGGCCGCTGCGGCCTGCGATCCTGTGGAATGACGGCCGCTCGCAAGCTGAATG
CGCCGAGCTCGAACGGCGTTGCCCGGAGTTGCACGCGATCGCCGGCAATCTCGCGATGCCCGGCTTCACCGCACCGAAGC
TGGTGTGGGTGGCAAAGCACGAGCCGGAGATCTTCGCTCAGGTGGCCAAGGTGCTGCTGCCGAAGGCGTATGTGCGTTAC
CGACTGTCCGGAGAAATGGCCGAGGACATGTCGGATGCAGCAGGCACCTTGTGGCTCGATGTCGGCGCGCGGCGCTGGTC
GGAGAAGCTGCTGGCGGCGACGGATCTCGGACTCGATCACATGCCGCGGCTGGTCGAAGGCAATGAGCGCAGCGCGGTGC
TGTCGCGCGCGCTGGCGCAGCGCTGGGGCATGAGCGGCGAGGTCGTGATCGCCGGCGGCGCAGGCGACAATGCCGCCAGC
GCGATCGGGCTCGGCGCGATCACGCCCGGCGACGCATTCCTGTCGCTGGGCACCTCAGGCGTGCTATTCCGCGTCACCGA
CCGCTTCGCGCCGGCGCCGGAGGCGGCCGTGCATGCGTTCTGTCACGCGCTCGGCGGGCTCTGGCACCAGATGGGCGTGA
TGCTGTCGGCCGCGGCCTCGCTGTCCTGGCTGGCGCGCATCCTCGCGACGCCCGAATCTGCGCTGCTGGCGCCGCTCGGC
GTCCGCGTCGATCGTCCGAGCCCGGTGCAGTTCCTGCCGTATCTCGATGGCGAGCGCACGCCGCACAATGACGCGCATGC
GGCGGGCGCGCTGGTCGGTCTGCGCAGCGCCGCGTCGCGCGACGATCTCGTGCAGGCCGTGCTCGAAGGCGTCGCCTATG
CCTCGCGCGACATGCTCGCCGCGCTCGGCCGCAGCGCGCAGCAGATCACGGCCCTCGATCTGGTCGGCGGCGGTTCGCGC
TCCGTCGTGTGGGCGCAGATCATGGCCGATGTGCTCGGCGTGACGGTGCATCGCGTCGAGGAGGGCGAGGTCGGCGCCGC
CATCGGCGCCGCCAGGCTCGGCCGTCTCGCCGCGACCGGCGAGGCGCCCGCCGATGTGTGCCGCAAGCCGCGGCGGCTGC
AGAGTTTCGAACCGCGCGCCGCGCAGCGCACCGCTTACGACGATGCCTATGCGCGCTGGCGCAAGCTCTATCCTGCTCTC
AAGGAGTAA

Upstream 100 bases:

>100_bases
TTTACGCAGCCGGCCGATCACGCAACGAAACGAAAGTGGGCCAGGTCCCGAAGCGACGAAGATCGCTCACGACCGACGGC
CCGTATGGGAGGAGGGAAGC

Downstream 100 bases:

>100_bases
CCGCTCGTGAACGTCCAGGCTCCCTTCTTCCACACCGGCGCGACCGTCGCTTATGGCGGCCAGGAGTCGCGCAGCCCGCT
GTCGTTCCGCTGGTACGACA

Product: xylulose kinase

Products: NA

Alternate protein names: Xylulokinase [H]

Number of amino acids: Translated: 482; Mature: 482

Protein sequence:

>482_residues
MFLGLDVGTSGVKAVLEDEAGALVASAGRPLALSHPQPLWSEQNPDHWVEAVIGAVDDLAARHPREVAVVRGIGLSGQMH
GATLLGRDGRPLRPAILWNDGRSQAECAELERRCPELHAIAGNLAMPGFTAPKLVWVAKHEPEIFAQVAKVLLPKAYVRY
RLSGEMAEDMSDAAGTLWLDVGARRWSEKLLAATDLGLDHMPRLVEGNERSAVLSRALAQRWGMSGEVVIAGGAGDNAAS
AIGLGAITPGDAFLSLGTSGVLFRVTDRFAPAPEAAVHAFCHALGGLWHQMGVMLSAAASLSWLARILATPESALLAPLG
VRVDRPSPVQFLPYLDGERTPHNDAHAAGALVGLRSAASRDDLVQAVLEGVAYASRDMLAALGRSAQQITALDLVGGGSR
SVVWAQIMADVLGVTVHRVEEGEVGAAIGAARLGRLAATGEAPADVCRKPRRLQSFEPRAAQRTAYDDAYARWRKLYPAL
KE

Sequences:

>Translated_482_residues
MFLGLDVGTSGVKAVLEDEAGALVASAGRPLALSHPQPLWSEQNPDHWVEAVIGAVDDLAARHPREVAVVRGIGLSGQMH
GATLLGRDGRPLRPAILWNDGRSQAECAELERRCPELHAIAGNLAMPGFTAPKLVWVAKHEPEIFAQVAKVLLPKAYVRY
RLSGEMAEDMSDAAGTLWLDVGARRWSEKLLAATDLGLDHMPRLVEGNERSAVLSRALAQRWGMSGEVVIAGGAGDNAAS
AIGLGAITPGDAFLSLGTSGVLFRVTDRFAPAPEAAVHAFCHALGGLWHQMGVMLSAAASLSWLARILATPESALLAPLG
VRVDRPSPVQFLPYLDGERTPHNDAHAAGALVGLRSAASRDDLVQAVLEGVAYASRDMLAALGRSAQQITALDLVGGGSR
SVVWAQIMADVLGVTVHRVEEGEVGAAIGAARLGRLAATGEAPADVCRKPRRLQSFEPRAAQRTAYDDAYARWRKLYPAL
KE
>Mature_482_residues
MFLGLDVGTSGVKAVLEDEAGALVASAGRPLALSHPQPLWSEQNPDHWVEAVIGAVDDLAARHPREVAVVRGIGLSGQMH
GATLLGRDGRPLRPAILWNDGRSQAECAELERRCPELHAIAGNLAMPGFTAPKLVWVAKHEPEIFAQVAKVLLPKAYVRY
RLSGEMAEDMSDAAGTLWLDVGARRWSEKLLAATDLGLDHMPRLVEGNERSAVLSRALAQRWGMSGEVVIAGGAGDNAAS
AIGLGAITPGDAFLSLGTSGVLFRVTDRFAPAPEAAVHAFCHALGGLWHQMGVMLSAAASLSWLARILATPESALLAPLG
VRVDRPSPVQFLPYLDGERTPHNDAHAAGALVGLRSAASRDDLVQAVLEGVAYASRDMLAALGRSAQQITALDLVGGGSR
SVVWAQIMADVLGVTVHRVEEGEVGAAIGAARLGRLAATGEAPADVCRKPRRLQSFEPRAAQRTAYDDAYARWRKLYPAL
KE

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI164663828, Length=538, Percent_Identity=24.5353159851301, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI41393575, Length=488, Percent_Identity=22.5409836065574, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI42794763, Length=439, Percent_Identity=21.6400911161731, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI4504007, Length=439, Percent_Identity=22.3234624145786, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI189409120, Length=441, Percent_Identity=22.2222222222222, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI18860918, Length=363, Percent_Identity=24.5179063360882, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI164663830, Length=562, Percent_Identity=23.6654804270463, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI88196792, Length=509, Percent_Identity=20.2357563850688, Blast_Score=76, Evalue=8e-14,
Organism=Escherichia coli, GI1789987, Length=485, Percent_Identity=48.4536082474227, Blast_Score=409, Evalue=1e-115,
Organism=Escherichia coli, GI1790361, Length=490, Percent_Identity=24.4897959183673, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1789168, Length=447, Percent_Identity=26.6219239373602, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1790005, Length=500, Percent_Identity=25, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1787789, Length=516, Percent_Identity=25.1937984496124, Blast_Score=106, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17535599, Length=447, Percent_Identity=24.3847874720358, Blast_Score=105, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17554530, Length=486, Percent_Identity=22.6337448559671, Blast_Score=91, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6321633, Length=216, Percent_Identity=27.3148148148148, Blast_Score=80, Evalue=7e-16,
Organism=Drosophila melanogaster, GI17864214, Length=438, Percent_Identity=23.7442922374429, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24654573, Length=409, Percent_Identity=23.4718826405868, Blast_Score=99, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24655555, Length=484, Percent_Identity=21.2809917355372, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24655560, Length=484, Percent_Identity=21.2809917355372, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24655570, Length=484, Percent_Identity=21.2809917355372, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24655574, Length=484, Percent_Identity=21.2809917355372, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24655565, Length=484, Percent_Identity=21.2809917355372, Blast_Score=91, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006000 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.17 [H]

Molecular weight: Translated: 51048; Mature: 51048

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: PS00933 FGGY_KINASES_1 ; PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLGLDVGTSGVKAVLEDEAGALVASAGRPLALSHPQPLWSEQNPDHWVEAVIGAVDDLA
CEEEECCCCHHHHHHHHCCCCEEEECCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHH
ARHPREVAVVRGIGLSGQMHGATLLGRDGRPLRPAILWNDGRSQAECAELERRCPELHAI
HCCCCCEEEEECCCCCCCCCCCEEECCCCCCCCCEEEECCCCCHHHHHHHHHHCCHHHHH
AGNLAMPGFTAPKLVWVAKHEPEIFAQVAKVLLPKAYVRYRLSGEMAEDMSDAAGTLWLD
HCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCEEEEE
VGARRWSEKLLAATDLGLDHMPRLVEGNERSAVLSRALAQRWGMSGEVVIAGGAGDNAAS
HHHHHHHHHHHHHHHCCHHHCCHHHCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHH
AIGLGAITPGDAFLSLGTSGVLFRVTDRFAPAPEAAVHAFCHALGGLWHQMGVMLSAAAS
HHCCCCCCCCHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSWLARILATPESALLAPLGVRVDRPSPVQFLPYLDGERTPHNDAHAAGALVGLRSAASR
HHHHHHHHHCCCHHHHHHCCCEECCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHCCH
DDLVQAVLEGVAYASRDMLAALGRSAQQITALDLVGGGSRSVVWAQIMADVLGVTVHRVE
HHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEEEECCCCCHHHHHHHHHHHHHHHHHEEC
EGEVGAAIGAARLGRLAATGEAPADVCRKPRRLQSFEPRAAQRTAYDDAYARWRKLYPAL
CCCCCHHHHHHHHHHHHCCCCCCHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
KE
CC
>Mature Secondary Structure
MFLGLDVGTSGVKAVLEDEAGALVASAGRPLALSHPQPLWSEQNPDHWVEAVIGAVDDLA
CEEEECCCCHHHHHHHHCCCCEEEECCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHH
ARHPREVAVVRGIGLSGQMHGATLLGRDGRPLRPAILWNDGRSQAECAELERRCPELHAI
HCCCCCEEEEECCCCCCCCCCCEEECCCCCCCCCEEEECCCCCHHHHHHHHHHCCHHHHH
AGNLAMPGFTAPKLVWVAKHEPEIFAQVAKVLLPKAYVRYRLSGEMAEDMSDAAGTLWLD
HCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCEEEEE
VGARRWSEKLLAATDLGLDHMPRLVEGNERSAVLSRALAQRWGMSGEVVIAGGAGDNAAS
HHHHHHHHHHHHHHHCCHHHCCHHHCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHH
AIGLGAITPGDAFLSLGTSGVLFRVTDRFAPAPEAAVHAFCHALGGLWHQMGVMLSAAAS
HHCCCCCCCCHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSWLARILATPESALLAPLGVRVDRPSPVQFLPYLDGERTPHNDAHAAGALVGLRSAASR
HHHHHHHHHCCCHHHHHHCCCEECCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHCCH
DDLVQAVLEGVAYASRDMLAALGRSAQQITALDLVGGGSRSVVWAQIMADVLGVTVHRVE
HHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEEEECCCCCHHHHHHHHHHHHHHHHHEEC
EGEVGAAIGAARLGRLAATGEAPADVCRKPRRLQSFEPRAAQRTAYDDAYARWRKLYPAL
CCCCCHHHHHHHHHHHHCCCCCCHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
KE
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6320721; 8041620; 9278503 [H]