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The map label for this gene is 146339067

Identifier: 146339067

GI number: 146339067

Start: 2151566

End: 2153317

Strand: Direct

Name: 146339067

Synonym: BRADO2021

Alternate gene names: NA

Gene position: 2151566-2153317 (Clockwise)

Preceding gene: 146339066

Following gene: 146339068

Centisome position: 28.85

GC content: 64.55

Gene sequence:

>1752_bases
TTGCTGCTTCCCGGTACCGTCCTGGCTCAGACTCCGGATCATCCGGCGGACACCGCCACGAAGTTTCCGACCAACGTCGA
TCTGAAATCGCTCACCACCTCGGGCAGCTATCTCGCCGCCCGCCACGCCAGCGTCGAACGCGACGCGGCGTCGGCCGCAG
CCTTCTACCGCTCCGCGCTGCGCAGCGATCCGAAGAACAACGAGCTGCTCGATCGCGCCTTCATCTCGTCGGTGGCCGAC
GGCGACATCGATGAAGCCGTGAAGCTCGCCGAGCGTGTGCTCTCCGTCGACAAGTCCAACCGCATCGCCCGCCTCGTGAT
GGGCGTGCAGGACATCAAGCAGAAGAAATACGCCTCCGCGCAGAACAACATCAATCAGTCGGTGCGCGGTCCGATCACCG
ATCTCGTCGCCACTCTGCTCTCGGCCTGGGCGACTGCCGGTGCGGGCGATTCCAAGGGCGCCGTGGCCAACATCGACAAG
CTGACCGGTCCGGAATGGTATCCGCTGTTCAAGGATCTTCACGCCGGCATGATCCTGGAGCTCGCCGGCAAGGAGAAGGA
AGCCGGCGCCCGCTTCGAGCGCGCCTACAAGCTCGACGATTCGATGCTGCGCATCACCGAGGCCTATGCGCACTGGCTGT
CGCGCAACAAGGACGCGGCCTCCGCCACCGCGATCTATGAGGCCTTCGACAAGAAGCTCGCGCGTCATCCGCTGGTGCTG
GAAGGCCTGCGCGACACCAAGGCCGGCAAGAAGCTGCCGCCGCTGGTCGATTCGCCGCAGGCCGGCGCCGCCGAGGCGCT
GTACGGCATCGGCGCGACCTTGAGCCGCCGCGGCGGCGAGGACCTTGCGCTGGTCTATCTGCAGCTCGCGCTGCATTTGC
AGCCGAACCATCCGCTGGCGCTGCTGTCGCTCGCCGACCTCTACGAGACGGTGAAGAAGCCGCAGATGGCGATCAAGGTC
TATGAGCGGGTGCCGGCCAGTTCGCCGCTGAAGCGCAACGCGCAGATCCAGCTCGCCACCGATCTCGACAGCGCCGACCG
CAGTGACGATGCGATCAAGATCCTCAAGGACGTGATCGCACAGGATCCGAAGGACCTCGAGGCCATCATGGCGCTTGGCA
ATATCGAGCGCGGCCGCAAGAAGTTCGCCGATTGCGCCAAGACCTACACGCTCGGCATCGATTCGCTGCCGGCGAACAAC
GACAAGGCGAACAGCGTCTATTACTACTATCGCGGCATCTGCCTTGAGCGCTCGAAGCAGTGGCCGAAGGCCGAGGCCGA
CATGCGCAAGGCGCTCGAGCTGCAGCCCGACCAGCCGCATGTGCTGAACTATCTCGGCTATTCCTGGATCGACCAGGGCA
TCAATCTCGACGAAGGCATGAAGATGATCAAGCGCGCCGTCGAGCAGCGTCCCGACGACGGCTACATCGTCGACTCGCTC
GGCTGGGCCTATTTCCGCATCGGCAATTACGAGGAGGCGGTGAAGAACCTCGAGCGCGCGATCGATCTCAAGCCCGAGGA
TCCGACCATCAACGATCATCTCGGCGACGCCTATTGGAAGGTCGGCCGCAAGCTCGAAGCCAAGTTCCAATGGGCTCATG
CCCGCGATCTGAAGCCGGAGCCCGAGGAGCTGCCGAAGATCGAGGCCAAGATCCAGAACGGCCTCACCGAGGATCCGGCG
CCGGCCGCCGCGAGCGCCGACACCAAGGACGCGCCGGCCGACGCCAAGAAGGACGACGGCAAGGGCGGCTAG

Upstream 100 bases:

>100_bases
ACCGGGTTCGAGTCCGATACGACCAATCCTTACCCAACAACCAGAGCGCACCGTGATGTTATTCATTCGCAATCGCTGGA
CCGCCATTGCCATTGCTGCC

Downstream 100 bases:

>100_bases
GTCGGTTCCGATCAGGATTGAAGCCATCACGGGCTCCTCGGCTTGCCGGGGAGCCCGGATTGATTTTGATGAAGGTGTGG
TGCTGCCGGCCACGTTCGTT

Product: TPR repeat-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 583; Mature: 583

Protein sequence:

>583_residues
MLLPGTVLAQTPDHPADTATKFPTNVDLKSLTTSGSYLAARHASVERDAASAAAFYRSALRSDPKNNELLDRAFISSVAD
GDIDEAVKLAERVLSVDKSNRIARLVMGVQDIKQKKYASAQNNINQSVRGPITDLVATLLSAWATAGAGDSKGAVANIDK
LTGPEWYPLFKDLHAGMILELAGKEKEAGARFERAYKLDDSMLRITEAYAHWLSRNKDAASATAIYEAFDKKLARHPLVL
EGLRDTKAGKKLPPLVDSPQAGAAEALYGIGATLSRRGGEDLALVYLQLALHLQPNHPLALLSLADLYETVKKPQMAIKV
YERVPASSPLKRNAQIQLATDLDSADRSDDAIKILKDVIAQDPKDLEAIMALGNIERGRKKFADCAKTYTLGIDSLPANN
DKANSVYYYYRGICLERSKQWPKAEADMRKALELQPDQPHVLNYLGYSWIDQGINLDEGMKMIKRAVEQRPDDGYIVDSL
GWAYFRIGNYEEAVKNLERAIDLKPEDPTINDHLGDAYWKVGRKLEAKFQWAHARDLKPEPEELPKIEAKIQNGLTEDPA
PAAASADTKDAPADAKKDDGKGG

Sequences:

>Translated_583_residues
MLLPGTVLAQTPDHPADTATKFPTNVDLKSLTTSGSYLAARHASVERDAASAAAFYRSALRSDPKNNELLDRAFISSVAD
GDIDEAVKLAERVLSVDKSNRIARLVMGVQDIKQKKYASAQNNINQSVRGPITDLVATLLSAWATAGAGDSKGAVANIDK
LTGPEWYPLFKDLHAGMILELAGKEKEAGARFERAYKLDDSMLRITEAYAHWLSRNKDAASATAIYEAFDKKLARHPLVL
EGLRDTKAGKKLPPLVDSPQAGAAEALYGIGATLSRRGGEDLALVYLQLALHLQPNHPLALLSLADLYETVKKPQMAIKV
YERVPASSPLKRNAQIQLATDLDSADRSDDAIKILKDVIAQDPKDLEAIMALGNIERGRKKFADCAKTYTLGIDSLPANN
DKANSVYYYYRGICLERSKQWPKAEADMRKALELQPDQPHVLNYLGYSWIDQGINLDEGMKMIKRAVEQRPDDGYIVDSL
GWAYFRIGNYEEAVKNLERAIDLKPEDPTINDHLGDAYWKVGRKLEAKFQWAHARDLKPEPEELPKIEAKIQNGLTEDPA
PAAASADTKDAPADAKKDDGKGG
>Mature_583_residues
MLLPGTVLAQTPDHPADTATKFPTNVDLKSLTTSGSYLAARHASVERDAASAAAFYRSALRSDPKNNELLDRAFISSVAD
GDIDEAVKLAERVLSVDKSNRIARLVMGVQDIKQKKYASAQNNINQSVRGPITDLVATLLSAWATAGAGDSKGAVANIDK
LTGPEWYPLFKDLHAGMILELAGKEKEAGARFERAYKLDDSMLRITEAYAHWLSRNKDAASATAIYEAFDKKLARHPLVL
EGLRDTKAGKKLPPLVDSPQAGAAEALYGIGATLSRRGGEDLALVYLQLALHLQPNHPLALLSLADLYETVKKPQMAIKV
YERVPASSPLKRNAQIQLATDLDSADRSDDAIKILKDVIAQDPKDLEAIMALGNIERGRKKFADCAKTYTLGIDSLPANN
DKANSVYYYYRGICLERSKQWPKAEADMRKALELQPDQPHVLNYLGYSWIDQGINLDEGMKMIKRAVEQRPDDGYIVDSL
GWAYFRIGNYEEAVKNLERAIDLKPEDPTINDHLGDAYWKVGRKLEAKFQWAHARDLKPEPEELPKIEAKIQNGLTEDPA
PAAASADTKDAPADAKKDDGKGG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 5 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI301336134, Length=265, Percent_Identity=26.4150943396226, Blast_Score=73, Evalue=8e-13,
Organism=Homo sapiens, GI83415184, Length=265, Percent_Identity=26.4150943396226, Blast_Score=73, Evalue=9e-13,
Organism=Drosophila melanogaster, GI161076610, Length=294, Percent_Identity=25.8503401360544, Blast_Score=66, Evalue=7e-11,
Organism=Drosophila melanogaster, GI19920486, Length=294, Percent_Identity=25.8503401360544, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011717
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR013105
- InterPro:   IPR019734 [H]

Pfam domain/function: PF07719 TPR_2; PF07721 TPR_4 [H]

EC number: NA

Molecular weight: Translated: 64013; Mature: 64013

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: PS50005 TPR L=RR ; PS50293 TPR_REGION L=RR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLPGTVLAQTPDHPADTATKFPTNVDLKSLTTSGSYLAARHASVERDAASAAAFYRSAL
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RSDPKNNELLDRAFISSVADGDIDEAVKLAERVLSVDKSNRIARLVMGVQDIKQKKYASA
HCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
QNNINQSVRGPITDLVATLLSAWATAGAGDSKGAVANIDKLTGPEWYPLFKDLHAGMILE
HHHCCHHHCCCHHHHHHHHHHHHHCCCCCCCCCCEECHHHHCCCCHHHHHHHHHCCCEEE
LAGKEKEAGARFERAYKLDDSMLRITEAYAHWLSRNKDAASATAIYEAFDKKLARHPLVL
ECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHH
EGLRDTKAGKKLPPLVDSPQAGAAEALYGIGATLSRRGGEDLALVYLQLALHLQPNHPLA
HCCHHCCCCCCCCCCCCCCCCCHHHHHHHHCHHHHHCCCCHHHHHHHHHHHHCCCCCCCH
LLSLADLYETVKKPQMAIKVYERVPASSPLKRNAQIQLATDLDSADRSDDAIKILKDVIA
HHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHH
QDPKDLEAIMALGNIERGRKKFADCAKTYTLGIDSLPANNDKANSVYYYYRGICLERSKQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEHHHHHHHCCC
WPKAEADMRKALELQPDQPHVLNYLGYSWIDQGINLDEGMKMIKRAVEQRPDDGYIVDSL
CCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEECCC
GWAYFRIGNYEEAVKNLERAIDLKPEDPTINDHLGDAYWKVGRKLEAKFQWAHARDLKPE
CEEEEEECCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEEHHHCCCCCC
PEELPKIEAKIQNGLTEDPAPAAASADTKDAPADAKKDDGKGG
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLLPGTVLAQTPDHPADTATKFPTNVDLKSLTTSGSYLAARHASVERDAASAAAFYRSAL
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RSDPKNNELLDRAFISSVADGDIDEAVKLAERVLSVDKSNRIARLVMGVQDIKQKKYASA
HCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
QNNINQSVRGPITDLVATLLSAWATAGAGDSKGAVANIDKLTGPEWYPLFKDLHAGMILE
HHHCCHHHCCCHHHHHHHHHHHHHCCCCCCCCCCEECHHHHCCCCHHHHHHHHHCCCEEE
LAGKEKEAGARFERAYKLDDSMLRITEAYAHWLSRNKDAASATAIYEAFDKKLARHPLVL
ECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHH
EGLRDTKAGKKLPPLVDSPQAGAAEALYGIGATLSRRGGEDLALVYLQLALHLQPNHPLA
HCCHHCCCCCCCCCCCCCCCCCHHHHHHHHCHHHHHCCCCHHHHHHHHHHHHCCCCCCCH
LLSLADLYETVKKPQMAIKVYERVPASSPLKRNAQIQLATDLDSADRSDDAIKILKDVIA
HHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHH
QDPKDLEAIMALGNIERGRKKFADCAKTYTLGIDSLPANNDKANSVYYYYRGICLERSKQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEHHHHHHHCCC
WPKAEADMRKALELQPDQPHVLNYLGYSWIDQGINLDEGMKMIKRAVEQRPDDGYIVDSL
CCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEECCC
GWAYFRIGNYEEAVKNLERAIDLKPEDPTINDHLGDAYWKVGRKLEAKFQWAHARDLKPE
CEEEEEECCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEEHHHCCCCCC
PEELPKIEAKIQNGLTEDPAPAAASADTKDAPADAKKDDGKGG
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7883699; 10984043 [H]