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The map label for this gene is nudL [H]

Identifier: 146339017

GI number: 146339017

Start: 2092990

End: 2093625

Strand: Direct

Name: nudL [H]

Synonym: BRADO1966

Alternate gene names: 146339017

Gene position: 2092990-2093625 (Clockwise)

Preceding gene: 146339016

Following gene: 146339018

Centisome position: 28.07

GC content: 65.25

Gene sequence:

>636_bases
GTGAGTTCGGCCGAATTCTTCGCGCGTGGCCGGGAGCGGCTGCGCTTCGACGTGCCGCCCGCGCTGCTCGATCCAGAGGT
CATTCCGACCAGCGGCGATTCTGGCACCGATCGCATGCTGGAGATCATCGCCCGCGAGCAGCCGATCCGGCCGGCTGCCG
TGCTCATTCCCGTGGTCGATCATCCCGAGCCGACGGTGCTCCTGACCCAGCGCTCGCCGAACTTGTCCAGCCATGCCGGG
CAGATCGCGTTTCCCGGCGGCAAGATCGACGTCACCGATGCCACCCCCCTCGACGCCGCCCTGCGCGAGGCGGAAGAGGA
GGTCGGCCTCGACCGCAGCTTCGTCGACCCGATCGGCTATCTCGATGTCTACGGCACCGCCTTCGGCTTCCGCATCCTGC
CGACGGTCGCCCGCGTAAGGCCTGGATTTTCGCTCAAGATCAACAAAGGCGAGGTCGACGACGCCTTCGAGGTGCCGCTC
GCCTTCCTGATGGACCCGGCCAATCACCAGCTGCATTCCAAGGAATTTCGCGGCATGGAGCGATCCTATTACGCGATGCC
GTTCGCCGAGCGCTACATCTGGGGCGCGACCGCAGGCATCCTTCGGGTGTTGTACGAGCGGATCTATCTGTCATGA

Upstream 100 bases:

>100_bases
GGGTGGAGTCGTCAGGCGCGTTCTTCCCCATGGCCAATGCAGACGAGGTGAGGGCGGCGCTTTGAACGAGCCCATGGTGG
CGAGGAGTGCGACGGACCGG

Downstream 100 bases:

>100_bases
TCCGACCCGTGTTGACGGAAATCGGAATCTTCCTCATTCCTTTTGCGGTTTATGTGCTGTTCTTGGTCGCGACCCGGGAG
GGGTTGCTGGTGCCGGCCAA

Product: putative NUDIX hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 211; Mature: 210

Protein sequence:

>211_residues
MSSAEFFARGRERLRFDVPPALLDPEVIPTSGDSGTDRMLEIIAREQPIRPAAVLIPVVDHPEPTVLLTQRSPNLSSHAG
QIAFPGGKIDVTDATPLDAALREAEEEVGLDRSFVDPIGYLDVYGTAFGFRILPTVARVRPGFSLKINKGEVDDAFEVPL
AFLMDPANHQLHSKEFRGMERSYYAMPFAERYIWGATAGILRVLYERIYLS

Sequences:

>Translated_211_residues
MSSAEFFARGRERLRFDVPPALLDPEVIPTSGDSGTDRMLEIIAREQPIRPAAVLIPVVDHPEPTVLLTQRSPNLSSHAG
QIAFPGGKIDVTDATPLDAALREAEEEVGLDRSFVDPIGYLDVYGTAFGFRILPTVARVRPGFSLKINKGEVDDAFEVPL
AFLMDPANHQLHSKEFRGMERSYYAMPFAERYIWGATAGILRVLYERIYLS
>Mature_210_residues
SSAEFFARGRERLRFDVPPALLDPEVIPTSGDSGTDRMLEIIAREQPIRPAAVLIPVVDHPEPTVLLTQRSPNLSSHAGQ
IAFPGGKIDVTDATPLDAALREAEEEVGLDRSFVDPIGYLDVYGTAFGFRILPTVARVRPGFSLKINKGEVDDAFEVPLA
FLMDPANHQLHSKEFRGMERSYYAMPFAERYIWGATAGILRVLYERIYLS

Specific function: Probably mediates the hydrolysis of some nucleoside diphosphate derivatives [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI157785656, Length=126, Percent_Identity=37.3015873015873, Blast_Score=69, Evalue=4e-12,
Organism=Escherichia coli, GI1788115, Length=159, Percent_Identity=42.1383647798742, Blast_Score=98, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17510677, Length=143, Percent_Identity=37.0629370629371, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17536993, Length=120, Percent_Identity=36.6666666666667, Blast_Score=64, Evalue=6e-11,
Organism=Drosophila melanogaster, GI18859683, Length=169, Percent_Identity=39.0532544378698, Blast_Score=79, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR000059 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: NA

Molecular weight: Translated: 23446; Mature: 23315

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSAEFFARGRERLRFDVPPALLDPEVIPTSGDSGTDRMLEIIAREQPIRPAAVLIPVVD
CCCHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEECC
HPEPTVLLTQRSPNLSSHAGQIAFPGGKIDVTDATPLDAALREAEEEVGLDRSFVDPIGY
CCCCCEEEEECCCCCCCCCCEEEECCCEEEECCCCCHHHHHHHHHHHHCCCCHHHCCCHH
LDVYGTAFGFRILPTVARVRPGFSLKINKGEVDDAFEVPLAFLMDPANHQLHSKEFRGME
HHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHCCHHEEECCCCCCHHHHHHCCCC
RSYYAMPFAERYIWGATAGILRVLYERIYLS
CCEEECCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SSAEFFARGRERLRFDVPPALLDPEVIPTSGDSGTDRMLEIIAREQPIRPAAVLIPVVD
CCHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEECC
HPEPTVLLTQRSPNLSSHAGQIAFPGGKIDVTDATPLDAALREAEEEVGLDRSFVDPIGY
CCCCCEEEEECCCCCCCCCCEEEECCCEEEECCCCCHHHHHHHHHHHHCCCCHHHCCCHH
LDVYGTAFGFRILPTVARVRPGFSLKINKGEVDDAFEVPLAFLMDPANHQLHSKEFRGME
HHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHCCHHEEECCCCCCHHHHHHCCCC
RSYYAMPFAERYIWGATAGILRVLYERIYLS
CCEEECCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA