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The map label for this gene is glpE [H]

Identifier: 146338908

GI number: 146338908

Start: 1973093

End: 1973830

Strand: Reverse

Name: glpE [H]

Synonym: BRADO1848

Alternate gene names: 146338908

Gene position: 1973830-1973093 (Counterclockwise)

Preceding gene: 146338909

Following gene: 146338907

Centisome position: 26.47

GC content: 65.45

Gene sequence:

>738_bases
GTGCTGCGCTTCGATGTCCGCGACCAGGCCTCGTTCAACGCGGCTCGCATGGCCGGCGCGCAACATCTCACCCAGCGCAA
CCTCTCCGAATTGATCGCCGGCACGAACAGGCGGACGGCGATCCTGATCTATTGCTATCACGGCCATGCAAGCCAGGAAT
ATGCGCAGACGTTCTCTGATTTCGGCTTCACGGAGGTCTACAGTCTCGACGGCGGCTATGAGGCGTGGCGGCTGCGCTTT
CCGGCACGCAACGGCGCGGCGGAGATCGGCCCGACTCTGGCGGCGTGGCTCACTGCCCAGGGTTTTCCGGCCGACGACGT
CGATGCCATCATCGACAACCGGACGACACCGCTGATGAAGGCGGCGCATCTCGGCAATATCACCGTGATCCGCGAGCTGC
TCGCCGCCGGCGCGGCCATCGCCGCGCGGAACGCCGACGGCAACAACGCGCTGTGGCTCGCCTGCGTCGGCCGGCATCTC
GAGGCCATTGATGCCTTGGTGGAGGCCGGCATCGACGTCGACAATTGCAACGACAATGGCGCGACGGCACTGATGTACGC
GTCGTCCTCAGGCAAGGACGATGTTGTCGCGCATCTGCTGGCCAAGGGCGCCGATATCACCACCGAGACGCTGGACGGCT
TCTCCGCGCTCGACATGGCTGCATCGCTCGAATGCCTGACGCTGCTGCGTCAGGCCGCTAAGGCGGCAGCGCGATCTGCC
CCCGAGATCCGGCCATGA

Upstream 100 bases:

>100_bases
GGCGCACACGCAACGAAGCAGGAGTCTCGCCATGAGACGGCGTATTCCATTCCAGCGCATCGATGTCGGGCACGCGGCGG
AGCTCTTGCAGCGCGACGAT

Downstream 100 bases:

>100_bases
CAGTGATCGAGCACGATTTCGGCAGGCAGCAGCGGCAGGTCGAGCGAAAGTTTCGTACCCTGCTCAGCCTCGATGCATTG
CACGAGGCCAATGTCCGCGC

Product: rhodanese-like domain-/ankyrin repeat-containing thiosulfate sulfurtransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MLRFDVRDQASFNAARMAGAQHLTQRNLSELIAGTNRRTAILIYCYHGHASQEYAQTFSDFGFTEVYSLDGGYEAWRLRF
PARNGAAEIGPTLAAWLTAQGFPADDVDAIIDNRTTPLMKAAHLGNITVIRELLAAGAAIAARNADGNNALWLACVGRHL
EAIDALVEAGIDVDNCNDNGATALMYASSSGKDDVVAHLLAKGADITTETLDGFSALDMAASLECLTLLRQAAKAAARSA
PEIRP

Sequences:

>Translated_245_residues
MLRFDVRDQASFNAARMAGAQHLTQRNLSELIAGTNRRTAILIYCYHGHASQEYAQTFSDFGFTEVYSLDGGYEAWRLRF
PARNGAAEIGPTLAAWLTAQGFPADDVDAIIDNRTTPLMKAAHLGNITVIRELLAAGAAIAARNADGNNALWLACVGRHL
EAIDALVEAGIDVDNCNDNGATALMYASSSGKDDVVAHLLAKGADITTETLDGFSALDMAASLECLTLLRQAAKAAARSA
PEIRP
>Mature_245_residues
MLRFDVRDQASFNAARMAGAQHLTQRNLSELIAGTNRRTAILIYCYHGHASQEYAQTFSDFGFTEVYSLDGGYEAWRLRF
PARNGAAEIGPTLAAWLTAQGFPADDVDAIIDNRTTPLMKAAHLGNITVIRELLAAGAAIAARNADGNNALWLACVGRHL
EAIDALVEAGIDVDNCNDNGATALMYASSSGKDDVVAHLLAKGADITTETLDGFSALDMAASLECLTLLRQAAKAAARSA
PEIRP

Specific function: Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide [H]

COG id: COG0666

COG function: function code R; FOG: Ankyrin repeat

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 rhodanese domain [H]

Homologues:

Organism=Homo sapiens, GI38683807, Length=131, Percent_Identity=36.6412213740458, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI38683816, Length=131, Percent_Identity=36.6412213740458, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI157739945, Length=148, Percent_Identity=35.8108108108108, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI52426735, Length=164, Percent_Identity=35.3658536585366, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI46519147, Length=96, Percent_Identity=37.5, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI37620163, Length=96, Percent_Identity=37.5, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI52426737, Length=164, Percent_Identity=35.3658536585366, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI188595682, Length=164, Percent_Identity=35.3658536585366, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI225543463, Length=138, Percent_Identity=35.5072463768116, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI225543461, Length=138, Percent_Identity=35.5072463768116, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI12746412, Length=108, Percent_Identity=37.962962962963, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI46519151, Length=212, Percent_Identity=31.6037735849057, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI46519154, Length=212, Percent_Identity=31.6037735849057, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI4506499, Length=108, Percent_Identity=36.1111111111111, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI19924156, Length=108, Percent_Identity=36.1111111111111, Blast_Score=65, Evalue=8e-11,
Organism=Homo sapiens, GI166235148, Length=122, Percent_Identity=35.2459016393443, Blast_Score=64, Evalue=9e-11,
Organism=Escherichia coli, GI1789831, Length=79, Percent_Identity=39.2405063291139, Blast_Score=67, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI71981411, Length=107, Percent_Identity=35.5140186915888, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI71981389, Length=123, Percent_Identity=33.3333333333333, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI25145251, Length=123, Percent_Identity=33.3333333333333, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17542700, Length=107, Percent_Identity=35.5140186915888, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71981414, Length=123, Percent_Identity=33.3333333333333, Blast_Score=64, Evalue=5e-11,
Organism=Drosophila melanogaster, GI28571867, Length=124, Percent_Identity=36.2903225806452, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28571865, Length=124, Percent_Identity=36.2903225806452, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281359521, Length=153, Percent_Identity=32.0261437908497, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281359519, Length=153, Percent_Identity=32.0261437908497, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28558752, Length=153, Percent_Identity=32.0261437908497, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28558750, Length=153, Percent_Identity=32.0261437908497, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28558756, Length=153, Percent_Identity=32.0261437908497, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28558754, Length=153, Percent_Identity=32.0261437908497, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24581260, Length=123, Percent_Identity=32.520325203252, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24581258, Length=123, Percent_Identity=32.520325203252, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI161082099, Length=106, Percent_Identity=36.7924528301887, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI161082085, Length=106, Percent_Identity=36.7924528301887, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI161082110, Length=106, Percent_Identity=36.7924528301887, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI161082096, Length=106, Percent_Identity=36.7924528301887, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI161082081, Length=106, Percent_Identity=36.7924528301887, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI161082106, Length=106, Percent_Identity=36.7924528301887, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI161082092, Length=107, Percent_Identity=36.4485981308411, Blast_Score=64, Evalue=8e-11,
Organism=Drosophila melanogaster, GI161082089, Length=107, Percent_Identity=36.4485981308411, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001763 [H]

Pfam domain/function: PF00581 Rhodanese [H]

EC number: =2.8.1.1 [H]

Molecular weight: Translated: 26125; Mature: 26125

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS50088 ANK_REPEAT ; PS50297 ANK_REP_REGION ; PS50206 RHODANESE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRFDVRDQASFNAARMAGAQHLTQRNLSELIAGTNRRTAILIYCYHGHASQEYAQTFSD
CCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCHHHHHHHHHH
FGFTEVYSLDGGYEAWRLRFPARNGAAEIGPTLAAWLTAQGFPADDVDAIIDNRTTPLMK
CCCEEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHCCCCCHHHH
AAHLGNITVIRELLAAGAAIAARNADGNNALWLACVGRHLEAIDALVEAGIDVDNCNDNG
HHHCCCHHHHHHHHHCCHHEEECCCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCCCC
ATALMYASSSGKDDVVAHLLAKGADITTETLDGFSALDMAASLECLTLLRQAAKAAARSA
CEEEEEECCCCCHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
PEIRP
CCCCC
>Mature Secondary Structure
MLRFDVRDQASFNAARMAGAQHLTQRNLSELIAGTNRRTAILIYCYHGHASQEYAQTFSD
CCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCHHHHHHHHHH
FGFTEVYSLDGGYEAWRLRFPARNGAAEIGPTLAAWLTAQGFPADDVDAIIDNRTTPLMK
CCCEEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHCCCCCHHHH
AAHLGNITVIRELLAAGAAIAARNADGNNALWLACVGRHLEAIDALVEAGIDVDNCNDNG
HHHCCCHHHHHHHHHCCHHEEECCCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCCCC
ATALMYASSSGKDDVVAHLLAKGADITTETLDGFSALDMAASLECLTLLRQAAKAAARSA
CEEEEEECCCCCHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
PEIRP
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA