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The map label for this gene is yfdE [H]

Identifier: 146338522

GI number: 146338522

Start: 1544626

End: 1545738

Strand: Reverse

Name: yfdE [H]

Synonym: BRADO1441

Alternate gene names: 146338522

Gene position: 1545738-1544626 (Counterclockwise)

Preceding gene: 146338523

Following gene: 146338521

Centisome position: 20.73

GC content: 67.65

Gene sequence:

>1113_bases
ATGCTGCCGCTTGAAGGGATCACCGTCGTTGCCGTCGAGCAGGCGGTGGCCGCGCCGTTCTGCTCGTCACGGCTGGCCGA
CGCCGGCGCCCATGTCATCAAGATCGAACGGCCGGAGGGCGACTTCGCCCGGGGCTATGATGCCGCCGCCAAGGGCCAGA
GCAGCTACTTCGTCTGGCTCAACCGCGGCAAGGATTCGCGCATCGTCGATCTGTCGAAGCCAGAGGGCCGCGCCGAGTTG
GAGATACTCATCGCAAGCGCCGACGTGCTGCTGCAGAACCTCAAGCCCGGCTCGATGGACAAGCTCGGCTTCGCGCGCGA
GCGGCTGCGCCAGGACTATCCGAAGCTGATCTGCTGCACCATCACCGGCTATGGCGACAGCGGCCCTTACGCCGACCGCA
AGGCCTATGATCTCCTGATCCAGGCCGAGAGCGGGCTCGCCTCCATCACCGGCGGCCCGGAAGGGCCGTCGCGCGTCGGC
ATGTCGATCGTCGACGTCGCCACCGGCGCAACCGCGCATGCGGCCATCCTGGAGGCGCTGATCAAGCGCGGCCGCACCGG
CGAGGGCGCGGACATCCGCATCTCGATGTTCGACGTCATGGCCGACTGGCTGACGGTGCCGCTGCTGAATGCCGAAGCAG
GCCAGGCGCCGAAGCGCATCGGCCTCGCCCATCCCTCGATCGCGCCCTATGGCGTGTTCACCTCGAAGGACGGCAAGGAC
ATCCTGATCTCGATCCAGAGCGAGCGCGAGTGGAAGACCTTGTGCGCCAAAGTGCTGGAGCAGCCCGCGCTGCCCGACGA
TCCGCGCTTCGCCAACATGGTCGAGCGGGTGCGCAACCGCGCGCTCACCGACAAGATCGTCGCCGATCGCTTCGCGGCGC
TGTCGCGCGACGAGCTGCTGGCGAAGCTCGCGGCCGCCGACATTGCCTTCGCCGAGGTCAACAGCATGACTGATCTCTCG
ACCCATCCGCATCTGCGGCGCATCGAGGTCGACACGCCGAATGGCGTCGTCAGCTATCCGGCCCCCGCCGCGATCGTGGT
CGGCGACGACAGGCGCTATGGCGCGGTACCCGCGATCGGCGATGCCGCCTCGCCTCACCAGCGAAAGGGATGA

Upstream 100 bases:

>100_bases
GATTGCTTCGCTGCGCTCGCAATGACGGAGGATAGACTTTTTTCGACGTCAAGCCCTCATGGTGGAGACCCCATGAGGCC
CCATTCCACGAGTTCACACC

Downstream 100 bases:

>100_bases
TCATGACGGAGTCCCTCGATCTCGATCACCTCCGGCAATGGGTCGGCCGCAGCACTGAAGCAACCGACATCGTCACCGCG
CAGCTCACCAAGGGCCTGCG

Product: formyl-coenzyme A transferase NAD(P)-binding

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 370; Mature: 370

Protein sequence:

>370_residues
MLPLEGITVVAVEQAVAAPFCSSRLADAGAHVIKIERPEGDFARGYDAAAKGQSSYFVWLNRGKDSRIVDLSKPEGRAEL
EILIASADVLLQNLKPGSMDKLGFARERLRQDYPKLICCTITGYGDSGPYADRKAYDLLIQAESGLASITGGPEGPSRVG
MSIVDVATGATAHAAILEALIKRGRTGEGADIRISMFDVMADWLTVPLLNAEAGQAPKRIGLAHPSIAPYGVFTSKDGKD
ILISIQSEREWKTLCAKVLEQPALPDDPRFANMVERVRNRALTDKIVADRFAALSRDELLAKLAAADIAFAEVNSMTDLS
THPHLRRIEVDTPNGVVSYPAPAAIVVGDDRRYGAVPAIGDAASPHQRKG

Sequences:

>Translated_370_residues
MLPLEGITVVAVEQAVAAPFCSSRLADAGAHVIKIERPEGDFARGYDAAAKGQSSYFVWLNRGKDSRIVDLSKPEGRAEL
EILIASADVLLQNLKPGSMDKLGFARERLRQDYPKLICCTITGYGDSGPYADRKAYDLLIQAESGLASITGGPEGPSRVG
MSIVDVATGATAHAAILEALIKRGRTGEGADIRISMFDVMADWLTVPLLNAEAGQAPKRIGLAHPSIAPYGVFTSKDGKD
ILISIQSEREWKTLCAKVLEQPALPDDPRFANMVERVRNRALTDKIVADRFAALSRDELLAKLAAADIAFAEVNSMTDLS
THPHLRRIEVDTPNGVVSYPAPAAIVVGDDRRYGAVPAIGDAASPHQRKG
>Mature_370_residues
MLPLEGITVVAVEQAVAAPFCSSRLADAGAHVIKIERPEGDFARGYDAAAKGQSSYFVWLNRGKDSRIVDLSKPEGRAEL
EILIASADVLLQNLKPGSMDKLGFARERLRQDYPKLICCTITGYGDSGPYADRKAYDLLIQAESGLASITGGPEGPSRVG
MSIVDVATGATAHAAILEALIKRGRTGEGADIRISMFDVMADWLTVPLLNAEAGQAPKRIGLAHPSIAPYGVFTSKDGKD
ILISIQSEREWKTLCAKVLEQPALPDDPRFANMVERVRNRALTDKIVADRFAALSRDELLAKLAAADIAFAEVNSMTDLS
THPHLRRIEVDTPNGVVSYPAPAAIVVGDDRRYGAVPAIGDAASPHQRKG

Specific function: Unknown

COG id: COG1804

COG function: function code C; Predicted acyl-CoA transferases/carnitine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CaiB/BaiF CoA-transferase family [H]

Homologues:

Organism=Homo sapiens, GI300863128, Length=350, Percent_Identity=34.2857142857143, Blast_Score=199, Evalue=4e-51,
Organism=Homo sapiens, GI300863124, Length=326, Percent_Identity=34.6625766871166, Blast_Score=193, Evalue=2e-49,
Organism=Homo sapiens, GI13376042, Length=325, Percent_Identity=32, Blast_Score=159, Evalue=3e-39,
Organism=Homo sapiens, GI300863126, Length=348, Percent_Identity=30.1724137931034, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI266456254, Length=329, Percent_Identity=27.9635258358663, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI42794625, Length=329, Percent_Identity=27.9635258358663, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI266458397, Length=270, Percent_Identity=30, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI266458393, Length=199, Percent_Identity=34.6733668341709, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI42822893, Length=144, Percent_Identity=35.4166666666667, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI266458395, Length=144, Percent_Identity=35.4166666666667, Blast_Score=86, Evalue=4e-17,
Organism=Escherichia coli, GI87082093, Length=319, Percent_Identity=34.7962382445141, Blast_Score=200, Evalue=1e-52,
Organism=Escherichia coli, GI1788717, Length=361, Percent_Identity=31.0249307479224, Blast_Score=128, Evalue=7e-31,
Organism=Escherichia coli, GI1786222, Length=331, Percent_Identity=26.8882175226586, Blast_Score=83, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI115535051, Length=325, Percent_Identity=25.5384615384615, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI32564160, Length=205, Percent_Identity=29.7560975609756, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24648431, Length=339, Percent_Identity=35.1032448377581, Blast_Score=186, Evalue=3e-47,
Organism=Drosophila melanogaster, GI24585488, Length=373, Percent_Identity=25.201072386059, Blast_Score=92, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003673 [H]

Pfam domain/function: PF02515 CoA_transf_3 [H]

EC number: NA

Molecular weight: Translated: 39681; Mature: 39681

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPLEGITVVAVEQAVAAPFCSSRLADAGAHVIKIERPEGDFARGYDAAAKGQSSYFVWL
CCCCCCEEEEEEHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHCCCCHHHCCCCCEEEEE
NRGKDSRIVDLSKPEGRAELEILIASADVLLQNLKPGSMDKLGFARERLRQDYPKLICCT
ECCCCCEEEECCCCCCCCEEEEEEEHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEE
ITGYGDSGPYADRKAYDLLIQAESGLASITGGPEGPSRVGMSIVDVATGATAHAAILEAL
EECCCCCCCCCCCCEEEEEEEECCCCEECCCCCCCHHHHCCEEEEHHCCCHHHHHHHHHH
IKRGRTGEGADIRISMFDVMADWLTVPLLNAEAGQAPKRIGLAHPSIAPYGVFTSKDGKD
HHCCCCCCCCEEEEEHHHHHHHHHHHEEECCCCCCCCHHHCCCCCCCCCCEEEECCCCCE
ILISIQSEREWKTLCAKVLEQPALPDDPRFANMVERVRNRALTDKIVADRFAALSRDELL
EEEEEECCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKLAAADIAFAEVNSMTDLSTHPHLRRIEVDTPNGVVSYPAPAAIVVGDDRRYGAVPAIG
HHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCEEECCCCEEEEEECCCCCCCCCCCC
DAASPHQRKG
CCCCCCCCCC
>Mature Secondary Structure
MLPLEGITVVAVEQAVAAPFCSSRLADAGAHVIKIERPEGDFARGYDAAAKGQSSYFVWL
CCCCCCEEEEEEHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHCCCCHHHCCCCCEEEEE
NRGKDSRIVDLSKPEGRAELEILIASADVLLQNLKPGSMDKLGFARERLRQDYPKLICCT
ECCCCCEEEECCCCCCCCEEEEEEEHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEE
ITGYGDSGPYADRKAYDLLIQAESGLASITGGPEGPSRVGMSIVDVATGATAHAAILEAL
EECCCCCCCCCCCCEEEEEEEECCCCEECCCCCCCHHHHCCEEEEHHCCCHHHHHHHHHH
IKRGRTGEGADIRISMFDVMADWLTVPLLNAEAGQAPKRIGLAHPSIAPYGVFTSKDGKD
HHCCCCCCCCEEEEEHHHHHHHHHHHEEECCCCCCCCHHHCCCCCCCCCCEEEECCCCCE
ILISIQSEREWKTLCAKVLEQPALPDDPRFANMVERVRNRALTDKIVADRFAALSRDELL
EEEEEECCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKLAAADIAFAEVNSMTDLSTHPHLRRIEVDTPNGVVSYPAPAAIVVGDDRRYGAVPAIG
HHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCEEECCCCEEEEEECCCCCCCCCCCC
DAASPHQRKG
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503; 8125343 [H]