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The map label for this gene is ftsK [H]

Identifier: 146338472

GI number: 146338472

Start: 1481133

End: 1483010

Strand: Reverse

Name: ftsK [H]

Synonym: BRADO1389

Alternate gene names: 146338472

Gene position: 1483010-1481133 (Counterclockwise)

Preceding gene: 146338473

Following gene: 146338471

Centisome position: 19.89

GC content: 65.97

Gene sequence:

>1878_bases
ATGGCGCATCACAGCATAACGGCGACAGAGCTCACCTTCGCCGTGCTCGATCCCGACTGGCGCGCCAGATGGCTGCGTGG
CGAGAAGCCGTCGACCAAGAGCTTCGCGCCGGTCGGCACAGTGCGTGCGATGGGCGTGACGTTCCACAAGGAGGTCGAGA
AGCTGGTCGGCTGGCTGACGGCGCGCGGCAGCCTGAGGGCCGCGTCAAGGATCGATACCGTCGATGCGCTGGTCGATCAT
CTCTGGGCGAATTCGCTGCAGGCCCTCACCGATAAATTGTTCGAAGCCGGCCGCGGCGAGGACGCTGCGGTCTTCACCGA
GCGGATGCGCCGCTTCTGCGCCCGGCTGATCGCGCTGCGGGCACGGACGCGCCATTTCGAGAACTGGCAGGACGTCTTCG
TCGGTGCCGAGCAGAATCTGGCGCGTATTCCCGTGCCGGTCGGCAACACCGTCGTGGAAATCCGCGGCCGCGTCGATGCC
ATCCGCATCCATCCTGAGCAGCATCTCGAGGTCGTCGACTACAAGCTCAGCCAGGGCGCGCGGCAGAAGGCCGATCTGGT
GCAGCTTTCGATCTATGCGCACCTGTTGCCGATCTGGCGGCCAGGCTGCGAATTCGCAGGAACGCTGGAGTACTATCTGC
CGGACTTCCAGGAGGTCTCGGTCGCTCCGGAGGAGTTGAAGGACATCTTCACCGGCATGGTCGATCCGGTACTGCGGGAG
ATGTTCGACGACACGGCCGTCACGCCGTCGCGTTCCGCGGCCGCGACACCCGATACACGAGCGGTCCCGCCAACGCCCGT
CGAAGCAGGCGCGCCTGCGCTGCGGCCTGGCGCGAACCCGCTCGGCAAGGCCGTCGTCGAGGCTTTCAGCAGTTTCAATC
TCGCCGTCGACTGCGCCGACGTCATCGAGGGACCGCAATTGATCCGGCTACGGCTCACGCCGGGTCCCGGCGTGAAGGTC
GCCTCGCTCGCCAACCGCGCTGCCGACCTGCAGGTCAAGCTCGACCTCGCCGAGCCGCCGCTGATCAAGGCCGGCAAAGG
CTTCGTCATTCTCGATCTGCCGCGGCCTGATCCGAAGCCGTGCCTGCTGAAGGACGCGCTGGCCGGGCCGCTCGCATCCG
CCCTGAAGAGCACCGTGAGCTTCCCCGTCGGCATCGACGTTGAAGGCAACCCGATCATCGCCGATTTCGCCGATCCCAAC
ACCTGTCACGCGCTGGTCGCCGGCTCCACCGGAAGCGGCAAGAGCGAATGGCTCAAGGCCATGGTCGCCAGCATGCTGCT
ACGCGGCTCGCCCGAGCAGGTCAAGATCGCGCTGATCGATCCGAAGATCCTGACCTTCTCCGGCGTCGGCGGCAGTCCCT
ATCTGTGGCGCCCCGTCGCGACCACGCTTGGCGAGGCGCTGAGAATCCTGCGCGACGCCGTCAAGGAGATGGATGCGCGC
TATCAGATCCTGAACGGCGCGGGCGTCGTCAATCTCGACGACTACATCAAGGCGGGCAAGACCGACCTGCCCTTCCTGGT
GCTGATCTTCGACGAGTTCGCCGATTTGATCCTGGCCGGTCGCGACGACAAGAAGGAGTTCGAGGCGCTGGTCGCGCGCA
TCGCCGGCAAGGGCCGTGCCGCCGGCATCCATCTGGTGCTGGCGACCCAGCGTCCCGATCGCGCGGTCGTCACCGGACTG
ATCAAATCCAACCTGCCGCTCAAGGTCTGCCTGAAGGTCGCCAATGCCGTGAATGCGCAGATCGTGCTGGATGAACCCGG
CGCCGAGAGCCTGTTCGGCAAGGGCGACCTGCTGTGCGATCTCGGCCGTGGCCTGGTCCGCGCCCAGGGCCTGTTCATTC
CGCAGGCGGAGTTCTTGGCTGCGCTCGGCCGTCATTAG

Upstream 100 bases:

>100_bases
ACAGGCTCGGGCGCAAGGAGCTGCGCGATCCCTTGTTGCGCAGCGTCGAGGCGCATCCCAATCTCAAGGCCCATCCCGGG
CCCAAGACCATCTTCCTGCA

Downstream 100 bases:

>100_bases
TTCGCATCGACTGCTTGTCGGGTTTGCGACAATGAGTCGTCGGTTTGCGTCCGAATCCGCTGGTCCGGAAATTGCGAGAG
CAAGTCCAACGGCATCATCA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 625; Mature: 624

Protein sequence:

>625_residues
MAHHSITATELTFAVLDPDWRARWLRGEKPSTKSFAPVGTVRAMGVTFHKEVEKLVGWLTARGSLRAASRIDTVDALVDH
LWANSLQALTDKLFEAGRGEDAAVFTERMRRFCARLIALRARTRHFENWQDVFVGAEQNLARIPVPVGNTVVEIRGRVDA
IRIHPEQHLEVVDYKLSQGARQKADLVQLSIYAHLLPIWRPGCEFAGTLEYYLPDFQEVSVAPEELKDIFTGMVDPVLRE
MFDDTAVTPSRSAAATPDTRAVPPTPVEAGAPALRPGANPLGKAVVEAFSSFNLAVDCADVIEGPQLIRLRLTPGPGVKV
ASLANRAADLQVKLDLAEPPLIKAGKGFVILDLPRPDPKPCLLKDALAGPLASALKSTVSFPVGIDVEGNPIIADFADPN
TCHALVAGSTGSGKSEWLKAMVASMLLRGSPEQVKIALIDPKILTFSGVGGSPYLWRPVATTLGEALRILRDAVKEMDAR
YQILNGAGVVNLDDYIKAGKTDLPFLVLIFDEFADLILAGRDDKKEFEALVARIAGKGRAAGIHLVLATQRPDRAVVTGL
IKSNLPLKVCLKVANAVNAQIVLDEPGAESLFGKGDLLCDLGRGLVRAQGLFIPQAEFLAALGRH

Sequences:

>Translated_625_residues
MAHHSITATELTFAVLDPDWRARWLRGEKPSTKSFAPVGTVRAMGVTFHKEVEKLVGWLTARGSLRAASRIDTVDALVDH
LWANSLQALTDKLFEAGRGEDAAVFTERMRRFCARLIALRARTRHFENWQDVFVGAEQNLARIPVPVGNTVVEIRGRVDA
IRIHPEQHLEVVDYKLSQGARQKADLVQLSIYAHLLPIWRPGCEFAGTLEYYLPDFQEVSVAPEELKDIFTGMVDPVLRE
MFDDTAVTPSRSAAATPDTRAVPPTPVEAGAPALRPGANPLGKAVVEAFSSFNLAVDCADVIEGPQLIRLRLTPGPGVKV
ASLANRAADLQVKLDLAEPPLIKAGKGFVILDLPRPDPKPCLLKDALAGPLASALKSTVSFPVGIDVEGNPIIADFADPN
TCHALVAGSTGSGKSEWLKAMVASMLLRGSPEQVKIALIDPKILTFSGVGGSPYLWRPVATTLGEALRILRDAVKEMDAR
YQILNGAGVVNLDDYIKAGKTDLPFLVLIFDEFADLILAGRDDKKEFEALVARIAGKGRAAGIHLVLATQRPDRAVVTGL
IKSNLPLKVCLKVANAVNAQIVLDEPGAESLFGKGDLLCDLGRGLVRAQGLFIPQAEFLAALGRH
>Mature_624_residues
AHHSITATELTFAVLDPDWRARWLRGEKPSTKSFAPVGTVRAMGVTFHKEVEKLVGWLTARGSLRAASRIDTVDALVDHL
WANSLQALTDKLFEAGRGEDAAVFTERMRRFCARLIALRARTRHFENWQDVFVGAEQNLARIPVPVGNTVVEIRGRVDAI
RIHPEQHLEVVDYKLSQGARQKADLVQLSIYAHLLPIWRPGCEFAGTLEYYLPDFQEVSVAPEELKDIFTGMVDPVLREM
FDDTAVTPSRSAAATPDTRAVPPTPVEAGAPALRPGANPLGKAVVEAFSSFNLAVDCADVIEGPQLIRLRLTPGPGVKVA
SLANRAADLQVKLDLAEPPLIKAGKGFVILDLPRPDPKPCLLKDALAGPLASALKSTVSFPVGIDVEGNPIIADFADPNT
CHALVAGSTGSGKSEWLKAMVASMLLRGSPEQVKIALIDPKILTFSGVGGSPYLWRPVATTLGEALRILRDAVKEMDARY
QILNGAGVVNLDDYIKAGKTDLPFLVLIFDEFADLILAGRDDKKEFEALVARIAGKGRAAGIHLVLATQRPDRAVVTGLI
KSNLPLKVCLKVANAVNAQIVLDEPGAESLFGKGDLLCDLGRGLVRAQGLFIPQAEFLAALGRH

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=370, Percent_Identity=36.4864864864865, Blast_Score=209, Evalue=4e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 67508; Mature: 67377

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHHSITATELTFAVLDPDWRARWLRGEKPSTKSFAPVGTVRAMGVTFHKEVEKLVGWLT
CCCCCEEHEEEEEEEECCCHHHHHHCCCCCCCCCCCCCCHHHHHCHHHHHHHHHHHHHHH
ARGSLRAASRIDTVDALVDHLWANSLQALTDKLFEAGRGEDAAVFTERMRRFCARLIALR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
ARTRHFENWQDVFVGAEQNLARIPVPVGNTVVEIRGRVDAIRIHPEQHLEVVDYKLSQGA
HHHHHCCCHHHHEECCCCCCEECCCCCCCEEEEECCCEEEEEECCHHHHHHHHHHHHCCC
RQKADLVQLSIYAHLLPIWRPGCEFAGTLEYYLPDFQEVSVAPEELKDIFTGMVDPVLRE
CHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHH
MFDDTAVTPSRSAAATPDTRAVPPTPVEAGAPALRPGANPLGKAVVEAFSSFNLAVDCAD
HHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEHHH
VIEGPQLIRLRLTPGPGVKVASLANRAADLQVKLDLAEPPLIKAGKGFVILDLPRPDPKP
HHCCCEEEEEEECCCCCEEHHHHHCCCCCEEEEEECCCCCCEECCCCEEEEECCCCCCCC
CLLKDALAGPLASALKSTVSFPVGIDVEGNPIIADFADPNTCHALVAGSTGSGKSEWLKA
CHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEECCCCCCEEEEEECCCCCCHHHHHHH
MVASMLLRGSPEQVKIALIDPKILTFSGVGGSPYLWRPVATTLGEALRILRDAVKEMDAR
HHHHHHHCCCCCEEEEEEECCEEEEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHH
YQILNGAGVVNLDDYIKAGKTDLPFLVLIFDEFADLILAGRDDKKEFEALVARIAGKGRA
EEEECCCCEEEHHHHHHCCCCCCCEEEEEHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCC
AGIHLVLATQRPDRAVVTGLIKSNLPLKVCLKVANAVNAQIVLDEPGAESLFGKGDLLCD
CEEEEEEEECCCCHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEECCCCHHHCCCCCHHHH
LGRGLVRAQGLFIPQAEFLAALGRH
HHCHHHHHCCCCCCHHHHHHHHCCC
>Mature Secondary Structure 
AHHSITATELTFAVLDPDWRARWLRGEKPSTKSFAPVGTVRAMGVTFHKEVEKLVGWLT
CCCCEEHEEEEEEEECCCHHHHHHCCCCCCCCCCCCCCHHHHHCHHHHHHHHHHHHHHH
ARGSLRAASRIDTVDALVDHLWANSLQALTDKLFEAGRGEDAAVFTERMRRFCARLIALR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
ARTRHFENWQDVFVGAEQNLARIPVPVGNTVVEIRGRVDAIRIHPEQHLEVVDYKLSQGA
HHHHHCCCHHHHEECCCCCCEECCCCCCCEEEEECCCEEEEEECCHHHHHHHHHHHHCCC
RQKADLVQLSIYAHLLPIWRPGCEFAGTLEYYLPDFQEVSVAPEELKDIFTGMVDPVLRE
CHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHH
MFDDTAVTPSRSAAATPDTRAVPPTPVEAGAPALRPGANPLGKAVVEAFSSFNLAVDCAD
HHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEHHH
VIEGPQLIRLRLTPGPGVKVASLANRAADLQVKLDLAEPPLIKAGKGFVILDLPRPDPKP
HHCCCEEEEEEECCCCCEEHHHHHCCCCCEEEEEECCCCCCEECCCCEEEEECCCCCCCC
CLLKDALAGPLASALKSTVSFPVGIDVEGNPIIADFADPNTCHALVAGSTGSGKSEWLKA
CHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEECCCCCCEEEEEECCCCCCHHHHHHH
MVASMLLRGSPEQVKIALIDPKILTFSGVGGSPYLWRPVATTLGEALRILRDAVKEMDAR
HHHHHHHCCCCCEEEEEEECCEEEEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHH
YQILNGAGVVNLDDYIKAGKTDLPFLVLIFDEFADLILAGRDDKKEFEALVARIAGKGRA
EEEECCCCEEEHHHHHHCCCCCCCEEEEEHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCC
AGIHLVLATQRPDRAVVTGLIKSNLPLKVCLKVANAVNAQIVLDEPGAESLFGKGDLLCD
CEEEEEEEECCCCHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEECCCCHHHCCCCCHHHH
LGRGLVRAQGLFIPQAEFLAALGRH
HHCHHHHHCCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]