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The map label for this gene is speE [H]

Identifier: 146337784

GI number: 146337784

Start: 686001

End: 686924

Strand: Reverse

Name: speE [H]

Synonym: BRADO0662

Alternate gene names: 146337784

Gene position: 686924-686001 (Counterclockwise)

Preceding gene: 146337785

Following gene: 146337783

Centisome position: 9.21

GC content: 60.71

Gene sequence:

>924_bases
ATGCTTATCCGGTCGGTCATTTCAGGCGCACTCGCAGGTCTTCTCTCGCTCTCCGCCGCGCAGGCCCAGGACACCCGCAA
TCTGCTGGAGTCCAAGGAATCGCTCTACAACAACATCTATGTGTACGAGCAGGCGCCCTATCGCAGCATGACGTTCGGTC
ATAACCGGCGCATCTATACCGAAAGCGTCTACAACACCCGTGACGAGCTCGATTTGCCGGTCGACTATACCCGCTTCATG
ACCACGAGCGTGATGTACGCCAAAAACGTCAGTTCGATTTTGGAGATCGGCTTCGGCGGCGGCCGCACCGCATGGTACCT
CCACCGCTTCCTGCCCAAGGTGCAGGTCACCTCGGTGGAGCTCGACCCGACCGTGCTGGAGCTCGCCAAGAAATATTTCG
GCATCAAGGAGGAGCCGAACTTCCACGTCGCCAACCGCGACGGAAGGCTGTTCGTGCAGGAATCCAAGGATCGCTACGAC
ATCATCCTGATCGATGCCTATCGCGGCCCGTTCGTGCCGTTCCATCTGCTGACCAAGGAGTTCTATCAGCTGGTCAAGGA
CCATCTCGCCGAGGGCGGCGTGGTGGCGCAGAATGTCGAGCCGTCGACGATGCTGTTCGACGCCGCGGTCAAGACGATCC
ACAGCGTGTTCCCGCAGGTCGACTTCTACGAGGCCGGCGGCAACATCGTGATGGTCGCCTATCCCGGCGACGAGCGGAAG
CCCGAGGATCTCGCTGCGGTCGCGCAGGAGCGCGACAAGGAGTTCGGCTTCCGCTACAAGCTCGCCGACATGCTGGCGCA
GCGCAAGCGCATCGACATTGACAACGGCCAGGTAATCGACGCCAAGGCCAAGGTGTTGACCGACGACTTCGCGCCGGTCG
AGGCGCTGAAGAGCATCGAGCGCCACAACAAGAAGCTGCCATGA

Upstream 100 bases:

>100_bases
GAGCGCGGCTCGTGATCGAGGGACCCCCGTCCCGCGCCACGGAGCCGCCGAGCCGGGCGCGCTCGCTCCATTTTTCAAGC
CGAGGGAAACAGACGGTTCA

Downstream 100 bases:

>100_bases
GCGAGCACGTGTCCCGCGCGGGCGTGCTGGCGATCTACGTCTGCTCGTTCCTGGTCGGCTGCGTGCTGATGGGCTTCGAG
ATGCTCGGCAGCCGCTACCT

Product: putative spermidine synthase (methyl transferase)

Products: NA

Alternate protein names: Putrescine aminopropyltransferase; PAPT; SPDSY [H]

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MLIRSVISGALAGLLSLSAAQAQDTRNLLESKESLYNNIYVYEQAPYRSMTFGHNRRIYTESVYNTRDELDLPVDYTRFM
TTSVMYAKNVSSILEIGFGGGRTAWYLHRFLPKVQVTSVELDPTVLELAKKYFGIKEEPNFHVANRDGRLFVQESKDRYD
IILIDAYRGPFVPFHLLTKEFYQLVKDHLAEGGVVAQNVEPSTMLFDAAVKTIHSVFPQVDFYEAGGNIVMVAYPGDERK
PEDLAAVAQERDKEFGFRYKLADMLAQRKRIDIDNGQVIDAKAKVLTDDFAPVEALKSIERHNKKLP

Sequences:

>Translated_307_residues
MLIRSVISGALAGLLSLSAAQAQDTRNLLESKESLYNNIYVYEQAPYRSMTFGHNRRIYTESVYNTRDELDLPVDYTRFM
TTSVMYAKNVSSILEIGFGGGRTAWYLHRFLPKVQVTSVELDPTVLELAKKYFGIKEEPNFHVANRDGRLFVQESKDRYD
IILIDAYRGPFVPFHLLTKEFYQLVKDHLAEGGVVAQNVEPSTMLFDAAVKTIHSVFPQVDFYEAGGNIVMVAYPGDERK
PEDLAAVAQERDKEFGFRYKLADMLAQRKRIDIDNGQVIDAKAKVLTDDFAPVEALKSIERHNKKLP
>Mature_307_residues
MLIRSVISGALAGLLSLSAAQAQDTRNLLESKESLYNNIYVYEQAPYRSMTFGHNRRIYTESVYNTRDELDLPVDYTRFM
TTSVMYAKNVSSILEIGFGGGRTAWYLHRFLPKVQVTSVELDPTVLELAKKYFGIKEEPNFHVANRDGRLFVQESKDRYD
IILIDAYRGPFVPFHLLTKEFYQLVKDHLAEGGVVAQNVEPSTMLFDAAVKTIHSVFPQVDFYEAGGNIVMVAYPGDERK
PEDLAAVAQERDKEFGFRYKLADMLAQRKRIDIDNGQVIDAKAKVLTDDFAPVEALKSIERHNKKLP

Specific function: Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor [H]

COG id: COG0421

COG function: function code E; Spermidine synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the spermidine/spermine synthase family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17570359, Length=78, Percent_Identity=38.4615384615385, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI19921592, Length=145, Percent_Identity=29.6551724137931, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001045 [H]

Pfam domain/function: PF01564 Spermine_synth [H]

EC number: =2.5.1.16 [H]

Molecular weight: Translated: 34917; Mature: 34917

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIRSVISGALAGLLSLSAAQAQDTRNLLESKESLYNNIYVYEQAPYRSMTFGHNRRIYT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCEEEE
ESVYNTRDELDLPVDYTRFMTTSVMYAKNVSSILEIGFGGGRTAWYLHRFLPKVQVTSVE
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCEEEEEEE
LDPTVLELAKKYFGIKEEPNFHVANRDGRLFVQESKDRYDIILIDAYRGPFVPFHLLTKE
CCHHHHHHHHHHCCCCCCCCEEEECCCCEEEEEECCCCEEEEEEECCCCCCCHHHHHHHH
FYQLVKDHLAEGGVVAQNVEPSTMLFDAAVKTIHSVFPQVDFYEAGGNIVMVAYPGDERK
HHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEEECCCCCC
PEDLAAVAQERDKEFGFRYKLADMLAQRKRIDIDNGQVIDAKAKVLTDDFAPVEALKSIE
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCEEEECHHHHHCCCCHHHHHHHHHH
RHNKKLP
HHCCCCC
>Mature Secondary Structure
MLIRSVISGALAGLLSLSAAQAQDTRNLLESKESLYNNIYVYEQAPYRSMTFGHNRRIYT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCEEEE
ESVYNTRDELDLPVDYTRFMTTSVMYAKNVSSILEIGFGGGRTAWYLHRFLPKVQVTSVE
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCEEEEEEE
LDPTVLELAKKYFGIKEEPNFHVANRDGRLFVQESKDRYDIILIDAYRGPFVPFHLLTKE
CCHHHHHHHHHHCCCCCCCCEEEECCCCEEEEEECCCCEEEEEEECCCCCCCHHHHHHHH
FYQLVKDHLAEGGVVAQNVEPSTMLFDAAVKTIHSVFPQVDFYEAGGNIVMVAYPGDERK
HHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEEECCCCCC
PEDLAAVAQERDKEFGFRYKLADMLAQRKRIDIDNGQVIDAKAKVLTDDFAPVEALKSIE
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCEEEECHHHHHCCCCHHHHHHHHHH
RHNKKLP
HHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA