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The map label for this gene is namA [H]

Identifier: 146337747

GI number: 146337747

Start: 645354

End: 646466

Strand: Direct

Name: namA [H]

Synonym: BRADO0620

Alternate gene names: 146337747

Gene position: 645354-646466 (Clockwise)

Preceding gene: 146337746

Following gene: 146337748

Centisome position: 8.65

GC content: 68.1

Gene sequence:

>1113_bases
ATGAGCGCCCTGTTCACTCCCATCAAGCTGCGCGGCCTGGAGCTTGCCAACCGCATCGTCGTGTCGCCGATGTGCCAGTA
CTCGGCCGAGAACGGCGCCGCCAATGACTGGCACTTCACCCACATCAACACGCTGGCGCTGTCGGGTGCGGCGATGTTCT
GCATCGAGGCGACGCATGTCGAGCCGATCGGACGCATCACGCCTGGCTGCCTCGGGCTGTGGGACGATGCGACGGAAGCT
GCGCTGAAGCCGATCCTCGCCTCGGTACGCAAGCATGCGAAAACGGCGATCGCGATGCAGCTCGCCCATGCCGGCCGCAA
GGGCTCCAGCCACAAGCCGTGGGATGGCGGCCAGCAGATCGCGCTGAGCGAGGGCGGCTGGCAGACGGTCGCGCCGTCGG
CGCTGCCGCATAAGGAGGGCGAGCTTGCCCCGGAGGCGCTCGACACCGCTGGCCTTCAGCGCATCCGAGAGGCGTTCGTC
TCCGCGGCGCAGCGCGCTGCCCGCCTCGGGATCGATGCGATCGAGGTGCATGGCGCGCACGGCTATCTGCTGCATCAGTT
CCTGTCGCCGATCGCCAATCGGCGCAGCGACGCTTACGGCGGCTCGCTCGAAAATCGCATGCGCTTCCCGCTCCAAGTCT
TCGATGCCGTGCGCGCCGTCTTCCCGGCGGACAAGCCGGTCGGCATGCGCGTCTCGGCGACCGACTGGGTCGAGGGCGGC
TGGGATCTCGACCAGACGATTGCCTTTGCGAACGAGTTGAAGCGCCGCGGCGTCGACTGGATCGATGTGTCCTCGGGTGG
TGCGTCGCCGCTGCAGAAGATCACGCTCGGTCCCGGCTATCAGGTGCCGTTCGCAGACGCGGTGAAAAAGGCCACGGGAT
TGCCGACCATGGCGGTCGGCCTCATCACGCAGGCGCAGCAAGCGGAGGAGATCGTGGCCTCCGGCAAGGCCGACATGATC
GCGCTCGCCCGCGGCATGCTCTACGACCCGCGCTGGGGCTGGCATGCGGCGGCCGAGTTGGGCGGCCAGGTTGCCGCGCC
CCCGCAATATTGGCGCTCGCAGCCCTCGACGCACAAGGAGCTGTTCGGCCGGACGACGTTCGGCGCACGCTGA

Upstream 100 bases:

>100_bases
GAGCCGCAAGGCGGCGCAGCGACCGCGTTGACCCTGTCGCAGCCATCGCCGACACTCGCGGCTGAGATCATCCCATCATC
ATGTCAGCCTGGAACTCAGC

Downstream 100 bases:

>100_bases
CGTGCAATTGAACGAGCGTGACCCGCGGATCAGCATTGCAGAAATCCGCGGGTCATCATTCCGCCAGCGACACAGCGAAC
GATTGCCGCTGTTCGACGAA

Product: NADPH dehydrogenase

Products: NA

Alternate protein names: Xenobiotic reductase [H]

Number of amino acids: Translated: 370; Mature: 369

Protein sequence:

>370_residues
MSALFTPIKLRGLELANRIVVSPMCQYSAENGAANDWHFTHINTLALSGAAMFCIEATHVEPIGRITPGCLGLWDDATEA
ALKPILASVRKHAKTAIAMQLAHAGRKGSSHKPWDGGQQIALSEGGWQTVAPSALPHKEGELAPEALDTAGLQRIREAFV
SAAQRAARLGIDAIEVHGAHGYLLHQFLSPIANRRSDAYGGSLENRMRFPLQVFDAVRAVFPADKPVGMRVSATDWVEGG
WDLDQTIAFANELKRRGVDWIDVSSGGASPLQKITLGPGYQVPFADAVKKATGLPTMAVGLITQAQQAEEIVASGKADMI
ALARGMLYDPRWGWHAAAELGGQVAAPPQYWRSQPSTHKELFGRTTFGAR

Sequences:

>Translated_370_residues
MSALFTPIKLRGLELANRIVVSPMCQYSAENGAANDWHFTHINTLALSGAAMFCIEATHVEPIGRITPGCLGLWDDATEA
ALKPILASVRKHAKTAIAMQLAHAGRKGSSHKPWDGGQQIALSEGGWQTVAPSALPHKEGELAPEALDTAGLQRIREAFV
SAAQRAARLGIDAIEVHGAHGYLLHQFLSPIANRRSDAYGGSLENRMRFPLQVFDAVRAVFPADKPVGMRVSATDWVEGG
WDLDQTIAFANELKRRGVDWIDVSSGGASPLQKITLGPGYQVPFADAVKKATGLPTMAVGLITQAQQAEEIVASGKADMI
ALARGMLYDPRWGWHAAAELGGQVAAPPQYWRSQPSTHKELFGRTTFGAR
>Mature_369_residues
SALFTPIKLRGLELANRIVVSPMCQYSAENGAANDWHFTHINTLALSGAAMFCIEATHVEPIGRITPGCLGLWDDATEAA
LKPILASVRKHAKTAIAMQLAHAGRKGSSHKPWDGGQQIALSEGGWQTVAPSALPHKEGELAPEALDTAGLQRIREAFVS
AAQRAARLGIDAIEVHGAHGYLLHQFLSPIANRRSDAYGGSLENRMRFPLQVFDAVRAVFPADKPVGMRVSATDWVEGGW
DLDQTIAFANELKRRGVDWIDVSSGGASPLQKITLGPGYQVPFADAVKKATGLPTMAVGLITQAQQAEEIVASGKADMIA
LARGMLYDPRWGWHAAAELGGQVAAPPQYWRSQPSTHKELFGRTTFGAR

Specific function: Catalyzes the reduction of the double bond of an array of alpha, beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787939, Length=349, Percent_Identity=29.7994269340974, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1789463, Length=337, Percent_Identity=27.5964391691395, Blast_Score=107, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI72001454, Length=192, Percent_Identity=35.4166666666667, Blast_Score=108, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17564188, Length=197, Percent_Identity=32.994923857868, Blast_Score=107, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI17559804, Length=197, Percent_Identity=34.010152284264, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17540738, Length=245, Percent_Identity=26.9387755102041, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17559802, Length=179, Percent_Identity=34.6368715083799, Blast_Score=105, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17565138, Length=219, Percent_Identity=30.1369863013699, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17566914, Length=128, Percent_Identity=33.59375, Blast_Score=83, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6325086, Length=245, Percent_Identity=29.7959183673469, Blast_Score=94, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6321973, Length=234, Percent_Identity=28.2051282051282, Blast_Score=91, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN [H]

EC number: =1.6.99.1 [H]

Molecular weight: Translated: 39767; Mature: 39636

Theoretical pI: Translated: 8.14; Mature: 8.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSALFTPIKLRGLELANRIVVSPMCQYSAENGAANDWHFTHINTLALSGAAMFCIEATHV
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHCCCEEEEEEECCC
EPIGRITPGCLGLWDDATEAALKPILASVRKHAKTAIAMQLAHAGRKGSSHKPWDGGQQI
CCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEE
ALSEGGWQTVAPSALPHKEGELAPEALDTAGLQRIREAFVSAAQRAARLGIDAIEVHGAH
EECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
GYLLHQFLSPIANRRSDAYGGSLENRMRFPLQVFDAVRAVFPADKPVGMRVSATDWVEGG
HHHHHHHHHHHHHCCCCCCCCCHHHHHCCHHHHHHHHHHHCCCCCCCCEEEECCCCCCCC
WDLDQTIAFANELKRRGVDWIDVSSGGASPLQKITLGPGYQVPFADAVKKATGLPTMAVG
CCHHHHHHHHHHHHHCCCCEEEECCCCCCCHHEEECCCCCCCCHHHHHHHHCCCCHHHHH
LITQAQQAEEIVASGKADMIALARGMLYDPRWGWHAAAELGGQVAAPPQYWRSQPSTHKE
HHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCHHHHCCCCCHHHH
LFGRTTFGAR
HHCCCCCCCC
>Mature Secondary Structure 
SALFTPIKLRGLELANRIVVSPMCQYSAENGAANDWHFTHINTLALSGAAMFCIEATHV
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHCCCEEEEEEECCC
EPIGRITPGCLGLWDDATEAALKPILASVRKHAKTAIAMQLAHAGRKGSSHKPWDGGQQI
CCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEE
ALSEGGWQTVAPSALPHKEGELAPEALDTAGLQRIREAFVSAAQRAARLGIDAIEVHGAH
EECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
GYLLHQFLSPIANRRSDAYGGSLENRMRFPLQVFDAVRAVFPADKPVGMRVSATDWVEGG
HHHHHHHHHHHHHCCCCCCCCCHHHHHCCHHHHHHHHHHHCCCCCCCCEEEECCCCCCCC
WDLDQTIAFANELKRRGVDWIDVSSGGASPLQKITLGPGYQVPFADAVKKATGLPTMAVG
CCHHHHHHHHHHHHHCCCCEEEECCCCCCCHHEEECCCCCCCCHHHHHHHHCCCCHHHHH
LITQAQQAEEIVASGKADMIALARGMLYDPRWGWHAAAELGGQVAAPPQYWRSQPSTHKE
HHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCHHHHCCCCCHHHH
LFGRTTFGAR
HHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA