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The map label for this gene is argJ [H]

Identifier: 146337719

GI number: 146337719

Start: 602814

End: 604055

Strand: Reverse

Name: argJ [H]

Synonym: BRADO0588

Alternate gene names: 146337719

Gene position: 604055-602814 (Counterclockwise)

Preceding gene: 146337720

Following gene: 146337716

Centisome position: 8.1

GC content: 68.92

Gene sequence:

>1242_bases
ATGTCCTCTGCCGTCTCCCCGCTCGCCCCGACCGACGTCCCCGACATGCCGGCGCTCGCCGGCGTGAGGCTCGCGACCGC
CGCGGCCGGCATCCGCTACAAGAACCGCACCGACGTGCTGCTGGCGCTGCTCGATCCCGGCACCACCGTCGCCGGCGTGT
TCACCAAGTCGAAATGCCCCTCGGCCCCGGTCGAATGGTGCCGCGCCAAGCTGAAGGGCGGCAAGGCGCGCGCGCTGGTC
GTCAATTCCGGCAACGCCAACGCCTTCACCGGCAAGACCGGCAAGCAGTCGACGGCGCTGACGGCGTCGATCGCCGCCAA
GGCGGTCGGCTGCAAGCAGGACGAGATCTTCCTGGCCTCGACCGGCGTGATCGGCGAGCCGCTCGACGCCACCAAGTTCG
ACGGCGTGCTCGAAGGCCTCGCCGGCACCGCCGCGCCGGAGGACTGGATGGGCGCGGCGCGCGCCATCATGACCACCGAC
ACCTTCCCCAAGGTCGCGACCGCCACCGTCAAGCTCGGCAAGGCCAAGGTGACGATCAACGGCATGGCCAAGGGCGCCGG
CATGATCGCGCCCGACATGGCGACGATGCTGTCCTTCATCTTCACCGATGCGCCGATCACGGCGCCGGCGCTGCAGGCGC
TGCTCAAGGCCGGCGTCGAGGACACCTTCAACGCCGTGACGATCGATGGCGACACCTCGACCTCGGACACGCTGCTCGCC
TTCGCCACCGGCGCCGCCGCGGCCAAAGGCGCGACGAAGATCAGCCGGATCAGCGATCCCGCCGCCAAGGCCTTCGTGAA
GGCGTTCAACGCCGTGCTCGCCAATCTCGCCGAGCAGGTGGCGCGCGACGGCGAGGGCGCGCGCAAGCTGGTCGAGATCA
TCGTCGAGGGCGCCAAGACCAAACAGTCGGCGCGCAGGATCGCGATGTCGATCGCCAACTCGCCGCTGGTGAAGACCGCG
ATCGCCGGCGAGGACGCCAATTGGGGCCGCGTCGTGATGGCGGTCGGCAAAGCCGGCGAGCCGGCCGATCGCGACAAGCT
GTCGATCTCGTTCAACGGCATCCGCGTGGCGTCGAAGGGCGCGCGCGATCCGTCTTATGACGAGAAGGAGGTCTCGGAGG
CCATGAGGGCGCAGACCATCCAGATCAAGGTTGCGCTTGGGCTGGGCAAGGGCCGCGACCGCGTGCTGACCTGCGACCTC
ACCAAAGAGTATGTCGCGATCAACGGCGACTACCGCTCCTGA

Upstream 100 bases:

>100_bases
TTCGCGGGGATGACGACTGAGTGTGAGGGCACATCCCCTCCCACAAGCTTGATGAGGATGATACAGAGCGCTTCCCGCCA
TCCTGCCGGAAGCTACTCCG

Downstream 100 bases:

>100_bases
CGCCGTCGGCCAGCGACGGAGCGCGCAGGGCCTGCGCGCTCTCGAGCGGCCGCCTCGCGATCAACCGGCAATACGCGCGT
CCGCCACGGCCTTCTTGAAC

Product: bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein

Products: NA

Alternate protein names: Glutamate N-acetyltransferase; Ornithine acetyltransferase; OATase; Ornithine transacetylase; Amino-acid acetyltransferase; N-acetylglutamate synthase; AGS [H]

Number of amino acids: Translated: 413; Mature: 412

Protein sequence:

>413_residues
MSSAVSPLAPTDVPDMPALAGVRLATAAAGIRYKNRTDVLLALLDPGTTVAGVFTKSKCPSAPVEWCRAKLKGGKARALV
VNSGNANAFTGKTGKQSTALTASIAAKAVGCKQDEIFLASTGVIGEPLDATKFDGVLEGLAGTAAPEDWMGAARAIMTTD
TFPKVATATVKLGKAKVTINGMAKGAGMIAPDMATMLSFIFTDAPITAPALQALLKAGVEDTFNAVTIDGDTSTSDTLLA
FATGAAAAKGATKISRISDPAAKAFVKAFNAVLANLAEQVARDGEGARKLVEIIVEGAKTKQSARRIAMSIANSPLVKTA
IAGEDANWGRVVMAVGKAGEPADRDKLSISFNGIRVASKGARDPSYDEKEVSEAMRAQTIQIKVALGLGKGRDRVLTCDL
TKEYVAINGDYRS

Sequences:

>Translated_413_residues
MSSAVSPLAPTDVPDMPALAGVRLATAAAGIRYKNRTDVLLALLDPGTTVAGVFTKSKCPSAPVEWCRAKLKGGKARALV
VNSGNANAFTGKTGKQSTALTASIAAKAVGCKQDEIFLASTGVIGEPLDATKFDGVLEGLAGTAAPEDWMGAARAIMTTD
TFPKVATATVKLGKAKVTINGMAKGAGMIAPDMATMLSFIFTDAPITAPALQALLKAGVEDTFNAVTIDGDTSTSDTLLA
FATGAAAAKGATKISRISDPAAKAFVKAFNAVLANLAEQVARDGEGARKLVEIIVEGAKTKQSARRIAMSIANSPLVKTA
IAGEDANWGRVVMAVGKAGEPADRDKLSISFNGIRVASKGARDPSYDEKEVSEAMRAQTIQIKVALGLGKGRDRVLTCDL
TKEYVAINGDYRS
>Mature_412_residues
SSAVSPLAPTDVPDMPALAGVRLATAAAGIRYKNRTDVLLALLDPGTTVAGVFTKSKCPSAPVEWCRAKLKGGKARALVV
NSGNANAFTGKTGKQSTALTASIAAKAVGCKQDEIFLASTGVIGEPLDATKFDGVLEGLAGTAAPEDWMGAARAIMTTDT
FPKVATATVKLGKAKVTINGMAKGAGMIAPDMATMLSFIFTDAPITAPALQALLKAGVEDTFNAVTIDGDTSTSDTLLAF
ATGAAAAKGATKISRISDPAAKAFVKAFNAVLANLAEQVARDGEGARKLVEIIVEGAKTKQSARRIAMSIANSPLVKTAI
AGEDANWGRVVMAVGKAGEPADRDKLSISFNGIRVASKGARDPSYDEKEVSEAMRAQTIQIKVALGLGKGRDRVLTCDLT
KEYVAINGDYRS

Specific function: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis:the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate [H]

COG id: COG1364

COG function: function code E; N-acetylglutamate synthase (N-acetylornithine aminotransferase)

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgJ family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6323707, Length=417, Percent_Identity=37.410071942446, Blast_Score=239, Evalue=4e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002813
- InterPro:   IPR016117 [H]

Pfam domain/function: PF01960 ArgJ [H]

EC number: =2.3.1.35; =2.3.1.1 [H]

Molecular weight: Translated: 42549; Mature: 42418

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSAVSPLAPTDVPDMPALAGVRLATAAAGIRYKNRTDVLLALLDPGTTVAGVFTKSKCP
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCEECCCCEEEEEEECCCCEEEEEEECCCCC
SAPVEWCRAKLKGGKARALVVNSGNANAFTGKTGKQSTALTASIAAKAVGCKQDEIFLAS
CCHHHHHHHHHCCCCEEEEEEECCCCCEECCCCCCCCHHHHHHHHHHHCCCCCCCEEEEE
TGVIGEPLDATKFDGVLEGLAGTAAPEDWMGAARAIMTTDTFPKVATATVKLGKAKVTIN
CCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHEEECCCCCCCEEEEEEECEEEEEEE
GMAKGAGMIAPDMATMLSFIFTDAPITAPALQALLKAGVEDTFNAVTIDGDTSTSDTLLA
CCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCEEEECCCCCCCCEEEE
FATGAAAAKGATKISRISDPAAKAFVKAFNAVLANLAEQVARDGEGARKLVEIIVEGAKT
EECCCHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHH
KQSARRIAMSIANSPLVKTAIAGEDANWGRVVMAVGKAGEPADRDKLSISFNGIRVASKG
HHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEEECCCCCCCCCCEEEEEECCEEEECCC
ARDPSYDEKEVSEAMRAQTIQIKVALGLGKGRDRVLTCDLTKEYVAINGDYRS
CCCCCCCHHHHHHHHHCEEEEEEEEEECCCCCCEEEEEECCCCEEEECCCCCC
>Mature Secondary Structure 
SSAVSPLAPTDVPDMPALAGVRLATAAAGIRYKNRTDVLLALLDPGTTVAGVFTKSKCP
CCCCCCCCCCCCCCCCHHHHHHHHHHHHCCEECCCCEEEEEEECCCCEEEEEEECCCCC
SAPVEWCRAKLKGGKARALVVNSGNANAFTGKTGKQSTALTASIAAKAVGCKQDEIFLAS
CCHHHHHHHHHCCCCEEEEEEECCCCCEECCCCCCCCHHHHHHHHHHHCCCCCCCEEEEE
TGVIGEPLDATKFDGVLEGLAGTAAPEDWMGAARAIMTTDTFPKVATATVKLGKAKVTIN
CCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHEEECCCCCCCEEEEEEECEEEEEEE
GMAKGAGMIAPDMATMLSFIFTDAPITAPALQALLKAGVEDTFNAVTIDGDTSTSDTLLA
CCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCEEEECCCCCCCCEEEE
FATGAAAAKGATKISRISDPAAKAFVKAFNAVLANLAEQVARDGEGARKLVEIIVEGAKT
EECCCHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHH
KQSARRIAMSIANSPLVKTAIAGEDANWGRVVMAVGKAGEPADRDKLSISFNGIRVASKG
HHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEEECCCCCCCCCCEEEEEECCEEEECCC
ARDPSYDEKEVSEAMRAQTIQIKVALGLGKGRDRVLTCDLTKEYVAINGDYRS
CCCCCCCHHHHHHHHHCEEEEEEEEEECCCCCCEEEEEECCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]