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The map label for this gene is plp [H]

Identifier: 146337720

GI number: 146337720

Start: 604330

End: 605154

Strand: Reverse

Name: plp [H]

Synonym: BRADO0589

Alternate gene names: 146337720

Gene position: 605154-604330 (Counterclockwise)

Preceding gene: 146337722

Following gene: 146337719

Centisome position: 8.12

GC content: 65.82

Gene sequence:

>825_bases
TTGTCCCTGCTGGTCGCCCCCGCGCGCGCCGCCGACGATGCCAACCCGGTGCTGGCCAAGGTGAACGGTGCCGAAATCCG
CAAGAGCGACGTCGCGCTCGCGGAGGAGGAGCTTGGTCCGAGCCTCGCCCAGATGGACCCGGCGACCAAGGACGAGAACG
TGCTGTCGTTCCTGATCGACATGAAGCTCGTGTCGAAGGCGGCCGAGGACAAGAAGGTCGCCGAAAGCGAGGACTTCAAG
AAGCGCCTCGCTTTCACCCGCAACCGCCTGCTGATGGACAGCCTGCTCGCCAGCGAGGGCAAGGCCGCGACCACGCCGGA
CGCGATGAAGAAGGTCTATGAGGAGGCCTCCAAGCAGATCGGCGGCGAGCAGGAGGTGCATGCGCGCCACATCCTCGTCG
AGACCGAGGACGAGGCCAAGGCCGTCAAGGCCGAACTGGCCAAGGGCGCCGATTTCGCCGAGCTCGCCAAGAAGAAATCC
AAGGACCCCGGCGCGTCGGATGGCGGCGACCTGGGCTTCTTCACCAAGGAGCAGATGGTGCCGGAATTCGCCAACGTGGC
GTTCAGCATGGAGCCGGGCAAGATCTCGGATCCGGTGAAGACCCAGTTCGGCTGGCACATCATCAAGGTCGAAGAGAAGC
GCAACCGCAAGCCGCCGGAGTTCGAGCAGGTCAAGAGCCAGATCGAGACCTACGTCACCCGCAAGGCCCAGGCCGATTAC
GTCGGCAAGCTGCGCGAGGCGGCCAAGATCGAGCGCCTGGACAAGCCGGCCGCCGACGCCGCCAAGCCGGCGGACGCGAA
GCCGGCCGAGCCGGCGAAGAAGTAA

Upstream 100 bases:

>100_bases
CCCCTCTTCAAACCAAGGATTTTCCATGACCACGTCGTTCCCGGTTACGAAAACCGGCCTGCACTTCGGCCTTGCCACCG
CTCTTGCCGGCAGTCTCGCA

Downstream 100 bases:

>100_bases
GCGGTTAGCTTCTGCGCGGCGACTCGTCACTGATTTGTTAGATTGCCTTAACCGCCGCGTCACAAAAGGTGTCGTCCCGG
CCTTGAGCCGGGACCCATAC

Product: putative peptidylprolyl isomerase

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase plp; Rotamase plp [H]

Number of amino acids: Translated: 274; Mature: 273

Protein sequence:

>274_residues
MSLLVAPARAADDANPVLAKVNGAEIRKSDVALAEEELGPSLAQMDPATKDENVLSFLIDMKLVSKAAEDKKVAESEDFK
KRLAFTRNRLLMDSLLASEGKAATTPDAMKKVYEEASKQIGGEQEVHARHILVETEDEAKAVKAELAKGADFAELAKKKS
KDPGASDGGDLGFFTKEQMVPEFANVAFSMEPGKISDPVKTQFGWHIIKVEEKRNRKPPEFEQVKSQIETYVTRKAQADY
VGKLREAAKIERLDKPAADAAKPADAKPAEPAKK

Sequences:

>Translated_274_residues
MSLLVAPARAADDANPVLAKVNGAEIRKSDVALAEEELGPSLAQMDPATKDENVLSFLIDMKLVSKAAEDKKVAESEDFK
KRLAFTRNRLLMDSLLASEGKAATTPDAMKKVYEEASKQIGGEQEVHARHILVETEDEAKAVKAELAKGADFAELAKKKS
KDPGASDGGDLGFFTKEQMVPEFANVAFSMEPGKISDPVKTQFGWHIIKVEEKRNRKPPEFEQVKSQIETYVTRKAQADY
VGKLREAAKIERLDKPAADAAKPADAKPAEPAKK
>Mature_273_residues
SLLVAPARAADDANPVLAKVNGAEIRKSDVALAEEELGPSLAQMDPATKDENVLSFLIDMKLVSKAAEDKKVAESEDFKK
RLAFTRNRLLMDSLLASEGKAATTPDAMKKVYEEASKQIGGEQEVHARHILVETEDEAKAVKAELAKGADFAELAKKKSK
DPGASDGGDLGFFTKEQMVPEFANVAFSMEPGKISDPVKTQFGWHIIKVEEKRNRKPPEFEQVKSQIETYVTRKAQADYV
GKLREAAKIERLDKPAADAAKPADAKPAEPAKK

Specific function: Ppiases Accelerate The Folding Of Proteins. It Prefers Amino Acid Residues With Hydrophobic Side Chains Like Leucine And Phenylalanine In The P1 Position Of The Peptides Substrates. [C]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Homo sapiens, GI38679892, Length=100, Percent_Identity=39, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1790211, Length=83, Percent_Identity=49.3975903614458, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1786238, Length=102, Percent_Identity=39.2156862745098, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1786645, Length=121, Percent_Identity=33.8842975206612, Blast_Score=65, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17537235, Length=100, Percent_Identity=40, Blast_Score=68, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 29905; Mature: 29774

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLVAPARAADDANPVLAKVNGAEIRKSDVALAEEELGPSLAQMDPATKDENVLSFLID
CCEEECCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHH
MKLVSKAAEDKKVAESEDFKKRLAFTRNRLLMDSLLASEGKAATTPDAMKKVYEEASKQI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHC
GGEQEVHARHILVETEDEAKAVKAELAKGADFAELAKKKSKDPGASDGGDLGFFTKEQMV
CCCHHHHHHEEEEECCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHH
PEFANVAFSMEPGKISDPVKTQFGWHIIKVEEKRNRKPPEFEQVKSQIETYVTRKAQADY
HHHHHHEEECCCCCCCCCHHHHHCEEEEEEEHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
VGKLREAAKIERLDKPAADAAKPADAKPAEPAKK
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SLLVAPARAADDANPVLAKVNGAEIRKSDVALAEEELGPSLAQMDPATKDENVLSFLID
CEEECCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHH
MKLVSKAAEDKKVAESEDFKKRLAFTRNRLLMDSLLASEGKAATTPDAMKKVYEEASKQI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHC
GGEQEVHARHILVETEDEAKAVKAELAKGADFAELAKKKSKDPGASDGGDLGFFTKEQMV
CCCHHHHHHEEEEECCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHH
PEFANVAFSMEPGKISDPVKTQFGWHIIKVEEKRNRKPPEFEQVKSQIETYVTRKAQADY
HHHHHHEEECCCCCCCCCHHHHHCEEEEEEEHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
VGKLREAAKIERLDKPAADAAKPADAKPAEPAKK
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA