BacMap

Definition	Bradyrhizobium sp. ORS278 chromosome, complete genome.
Accession	NC_009445
Length	7,456,587

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The map label for this gene is phbB [H]

Identifier: 146337695

GI number: 146337695

Start: 578585

End: 579310

Strand: Direct

Name: phbB [H]

Synonym: BRADO0563

Alternate gene names: 146337695

Gene position: 578585-579310 (Clockwise)

Preceding gene: 146337694

Following gene: 146337696

Centisome position: 7.76

GC content: 63.36

Gene sequence:

>726_bases
ATGGCACGTGTGGCGTTGGTGACGGGAGGGACGCGCGGGATCGGCGCTGCGATCAGCAAGGCGCTGAAGGCAGCCGGCTA
CAAGGTCGCGGCGAATTATGGCGGCAACGATGCCGCCGCGGAGAAGTTCAAGAGCGAGACCGATATCCCCGTCTACAAGT
GGGACGTCAGCTCGTTCGAGGCCTGTTCCGAGGGGATCAAGAAGGTCGAGGCCGAGCTCGGGCCGATCGATGTGCTGATC
AACAACGCCGGCATCACCCGCGATACGGCCTTCCACAAGATGTCGCTCGAGCAGTGGAGCGTCGTCATCAACACCAATCT
CGGCTCGCTCTTCAACATGACCCGTCCGATCATCGAGGGCATGCGCGCGCGCAAGTTCGGCCGCATCATCAACATCTCGT
CGATCAACGGTCAGAAGGGCCAGTTCGGCCAGGTCAACTACTCCGCCGCGAAGGCCGGCGACATCGGCTTCACCAAGGCG
CTGGCGCTGGAGACCGCGAAGGCTGGCATCACTGTCAACGTGATCTGCCCCGGCTACATCAATACCGAGATGGTGCAGGC
AGTGCCGAAGGACGTGCTCGAAAAGTCGATTCTGCCGCTGATCCCCGTCGGCCGTCTCGGCGAGCCCGAAGAGATCGCCC
GCACTGTCGTGTTCCTCGCGGCCGACGAGGCCGGTGCCATCACCGGCTCGACCCTCTCCGTCAACGGCGGCCAGTACATG
GCCTGA

Upstream 100 bases:

>100_bases
GGATTGCTGCGAGGGCGGACGTGATCCAATAACAACGGGTAGGCACGCCGACATCCAGAGGTTGTCGTCGGGCCGTCAGT
CATCGAGGGAAGGATTCGAC

Downstream 100 bases:

>100_bases
TGCCGGCGCGATGCCGAAGGCGGCGTTGCCTCCGGACGCGATCTGCGGTTAAGACCACGAATGCCCGCGCCTGCCGCGGG
CATTCACGTCTTTGGCGTTG

Product: acetoacetyl-CoA reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 241; Mature: 240

Protein sequence:

>241_residues
MARVALVTGGTRGIGAAISKALKAAGYKVAANYGGNDAAAEKFKSETDIPVYKWDVSSFEACSEGIKKVEAELGPIDVLI
NNAGITRDTAFHKMSLEQWSVVINTNLGSLFNMTRPIIEGMRARKFGRIINISSINGQKGQFGQVNYSAAKAGDIGFTKA
LALETAKAGITVNVICPGYINTEMVQAVPKDVLEKSILPLIPVGRLGEPEEIARTVVFLAADEAGAITGSTLSVNGGQYM
A

Sequences:

>Translated_241_residues
MARVALVTGGTRGIGAAISKALKAAGYKVAANYGGNDAAAEKFKSETDIPVYKWDVSSFEACSEGIKKVEAELGPIDVLI
NNAGITRDTAFHKMSLEQWSVVINTNLGSLFNMTRPIIEGMRARKFGRIINISSINGQKGQFGQVNYSAAKAGDIGFTKA
LALETAKAGITVNVICPGYINTEMVQAVPKDVLEKSILPLIPVGRLGEPEEIARTVVFLAADEAGAITGSTLSVNGGQYM
A
>Mature_240_residues
ARVALVTGGTRGIGAAISKALKAAGYKVAANYGGNDAAAEKFKSETDIPVYKWDVSSFEACSEGIKKVEAELGPIDVLIN
NAGITRDTAFHKMSLEQWSVVINTNLGSLFNMTRPIIEGMRARKFGRIINISSINGQKGQFGQVNYSAAKAGDIGFTKAL
ALETAKAGITVNVICPGYINTEMVQAVPKDVLEKSILPLIPVGRLGEPEEIARTVVFLAADEAGAITGSTLSVNGGQYMA

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=250, Percent_Identity=39.6, Blast_Score=152, Evalue=3e-37,
Organism=Homo sapiens, GI40254992, Length=241, Percent_Identity=37.7593360995851, Blast_Score=140, Evalue=1e-33,
Organism=Homo sapiens, GI4504505, Length=232, Percent_Identity=37.0689655172414, Blast_Score=118, Evalue=6e-27,
Organism=Homo sapiens, GI7705925, Length=239, Percent_Identity=30.9623430962343, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI19923817, Length=257, Percent_Identity=31.9066147859922, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI66933014, Length=179, Percent_Identity=33.5195530726257, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI31542939, Length=252, Percent_Identity=30.5555555555556, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI32483357, Length=241, Percent_Identity=30.7053941908714, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI10190704, Length=247, Percent_Identity=30.7692307692308, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI4758504, Length=231, Percent_Identity=30.7359307359307, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI109715829, Length=235, Percent_Identity=31.063829787234, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI59889578, Length=182, Percent_Identity=33.5164835164835, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI4503301, Length=206, Percent_Identity=29.6116504854369, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI20149619, Length=200, Percent_Identity=31, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI5031737, Length=243, Percent_Identity=29.2181069958848, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI4503817, Length=227, Percent_Identity=27.7533039647577, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI7657478, Length=191, Percent_Identity=28.7958115183246, Blast_Score=71, Evalue=7e-13,
Organism=Homo sapiens, GI126723750, Length=245, Percent_Identity=26.9387755102041, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI83715985, Length=231, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI7706318, Length=193, Percent_Identity=28.4974093264249, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI40807363, Length=207, Percent_Identity=25.6038647342995, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI210032110, Length=186, Percent_Identity=25.8064516129032, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI142976729, Length=217, Percent_Identity=24.8847926267281, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI226371731, Length=204, Percent_Identity=29.9019607843137, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI224922801, Length=170, Percent_Identity=31.1764705882353, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI150247226, Length=186, Percent_Identity=28.494623655914, Blast_Score=64, Evalue=9e-11,
Organism=Escherichia coli, GI1787335, Length=242, Percent_Identity=46.2809917355372, Blast_Score=204, Evalue=3e-54,
Organism=Escherichia coli, GI87082100, Length=258, Percent_Identity=32.5581395348837, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI1790717, Length=241, Percent_Identity=31.1203319502075, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI2367175, Length=245, Percent_Identity=32.6530612244898, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI1789208, Length=248, Percent_Identity=32.6612903225806, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1788459, Length=247, Percent_Identity=31.5789473684211, Blast_Score=110, Evalue=6e-26,
Organism=Escherichia coli, GI1786812, Length=245, Percent_Identity=31.4285714285714, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI87082160, Length=241, Percent_Identity=30.7053941908714, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI2367365, Length=240, Percent_Identity=30.4166666666667, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1789057, Length=258, Percent_Identity=29.0697674418605, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1787820, Length=180, Percent_Identity=34.4444444444444, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1787905, Length=239, Percent_Identity=26.7782426778243, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1789378, Length=251, Percent_Identity=29.4820717131474, Blast_Score=71, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI25147288, Length=243, Percent_Identity=41.5637860082305, Blast_Score=166, Evalue=7e-42,
Organism=Caenorhabditis elegans, GI17555706, Length=253, Percent_Identity=40.3162055335968, Blast_Score=161, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI17560676, Length=251, Percent_Identity=32.2709163346614, Blast_Score=110, Evalue=8e-25,
Organism=Caenorhabditis elegans, GI71994600, Length=249, Percent_Identity=32.1285140562249, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI71994604, Length=249, Percent_Identity=32.5301204819277, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17568967, Length=232, Percent_Identity=31.4655172413793, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17561402, Length=247, Percent_Identity=32.3886639676113, Blast_Score=94, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17562910, Length=259, Percent_Identity=30.8880308880309, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17538182, Length=255, Percent_Identity=32.156862745098, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17559104, Length=260, Percent_Identity=28.8461538461538, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI193203115, Length=192, Percent_Identity=28.6458333333333, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17538486, Length=262, Percent_Identity=29.7709923664122, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI193203117, Length=192, Percent_Identity=28.6458333333333, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17562990, Length=263, Percent_Identity=29.277566539924, Blast_Score=84, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI115534694, Length=246, Percent_Identity=32.9268292682927, Blast_Score=84, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17560150, Length=264, Percent_Identity=29.5454545454545, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17562904, Length=256, Percent_Identity=28.515625, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17560332, Length=265, Percent_Identity=30.5660377358491, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17562906, Length=256, Percent_Identity=28.125, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17508651, Length=248, Percent_Identity=29.8387096774194, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17538480, Length=259, Percent_Identity=27.7992277992278, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17561272, Length=194, Percent_Identity=30.9278350515464, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17564282, Length=191, Percent_Identity=27.7486910994764, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI193204405, Length=257, Percent_Identity=28.0155642023346, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17536025, Length=248, Percent_Identity=29.4354838709677, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17562908, Length=260, Percent_Identity=27.3076923076923, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17536651, Length=248, Percent_Identity=28.2258064516129, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17544670, Length=265, Percent_Identity=24.5283018867925, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17551412, Length=260, Percent_Identity=26.1538461538462, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17563726, Length=256, Percent_Identity=28.515625, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17531453, Length=261, Percent_Identity=28.3524904214559, Blast_Score=70, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI72000259, Length=253, Percent_Identity=28.0632411067194, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17508895, Length=192, Percent_Identity=26.0416666666667, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17560220, Length=263, Percent_Identity=28.5171102661597, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17565030, Length=259, Percent_Identity=28.1853281853282, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=249, Percent_Identity=34.136546184739, Blast_Score=114, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6324126, Length=247, Percent_Identity=29.9595141700405, Blast_Score=84, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6320089, Length=209, Percent_Identity=29.6650717703349, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24639444, Length=244, Percent_Identity=38.1147540983607, Blast_Score=138, Evalue=3e-33,
Organism=Drosophila melanogaster, GI21357041, Length=248, Percent_Identity=35.0806451612903, Blast_Score=114, Evalue=7e-26,
Organism=Drosophila melanogaster, GI23397609, Length=246, Percent_Identity=32.520325203252, Blast_Score=110, Evalue=6e-25,
Organism=Drosophila melanogaster, GI24644339, Length=250, Percent_Identity=34.8, Blast_Score=110, Evalue=7e-25,
Organism=Drosophila melanogaster, GI28571526, Length=253, Percent_Identity=33.9920948616601, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI18859837, Length=207, Percent_Identity=33.8164251207729, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI21355319, Length=241, Percent_Identity=31.1203319502075, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI17737361, Length=261, Percent_Identity=32.9501915708812, Blast_Score=95, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24643142, Length=237, Percent_Identity=29.1139240506329, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24644337, Length=179, Percent_Identity=34.0782122905028, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI21355631, Length=167, Percent_Identity=32.9341317365269, Blast_Score=78, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24581726, Length=165, Percent_Identity=29.6969696969697, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24656154, Length=264, Percent_Identity=28.4090909090909, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI19922628, Length=264, Percent_Identity=28.4090909090909, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24665247, Length=202, Percent_Identity=32.1782178217822, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI221331216, Length=202, Percent_Identity=32.1782178217822, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI116007236, Length=198, Percent_Identity=30.8080808080808, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24584748, Length=186, Percent_Identity=29.5698924731183, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI221331218, Length=202, Percent_Identity=32.6732673267327, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI161076933, Length=186, Percent_Identity=29.5698924731183, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24665243, Length=202, Percent_Identity=32.6732673267327, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI28574402, Length=191, Percent_Identity=29.8429319371728, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24584744, Length=191, Percent_Identity=29.8429319371728, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24649181, Length=187, Percent_Identity=28.8770053475936, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI21358495, Length=192, Percent_Identity=29.1666666666667, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24641232, Length=234, Percent_Identity=28.6324786324786, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI116007234, Length=237, Percent_Identity=29.1139240506329, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21356301, Length=189, Percent_Identity=28.042328042328, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24665264, Length=222, Percent_Identity=27.027027027027, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011283
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.36 [H]

Molecular weight: Translated: 25413; Mature: 25281

Theoretical pI: Translated: 8.65; Mature: 8.65

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARVALVTGGTRGIGAAISKALKAAGYKVAANYGGNDAAAEKFKSETDIPVYKWDVSSFE
CCEEEEEECCCCCHHHHHHHHHHHCCEEEEECCCCCHHHHHHHCCCCCCEEEEECCHHHH
ACSEGIKKVEAELGPIDVLINNAGITRDTAFHKMSLEQWSVVINTNLGSLFNMTRPIIEG
HHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHCCHHHEEEEEECCCHHHHHHHHHHHHH
MRARKFGRIINISSINGQKGQFGQVNYSAAKAGDIGFTKALALETAKAGITVNVICPGYI
HHHHHCCCEEEEEECCCCCCCCCCEECCCCCCCCCCHHHHHHHHHHCCCEEEEEEECCCC
NTEMVQAVPKDVLEKSILPLIPVGRLGEPEEIARTVVFLAADEAGAITGSTLSVNGGQYM
CHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHEEEEEEECCCCCEECCEEEECCCCCC
A
C
>Mature Secondary Structure 
ARVALVTGGTRGIGAAISKALKAAGYKVAANYGGNDAAAEKFKSETDIPVYKWDVSSFE
CEEEEEECCCCCHHHHHHHHHHHCCEEEEECCCCCHHHHHHHCCCCCCEEEEECCHHHH
ACSEGIKKVEAELGPIDVLINNAGITRDTAFHKMSLEQWSVVINTNLGSLFNMTRPIIEG
HHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHCCHHHEEEEEECCCHHHHHHHHHHHHH
MRARKFGRIINISSINGQKGQFGQVNYSAAKAGDIGFTKALALETAKAGITVNVICPGYI
HHHHHCCCEEEEEECCCCCCCCCCEECCCCCCCCCCHHHHHHHHHHCCCEEEEEEECCCC
NTEMVQAVPKDVLEKSILPLIPVGRLGEPEEIARTVVFLAADEAGAITGSTLSVNGGQYM
CHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHEEEEEEECCCCCEECCEEEECCCCCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2546004; 3286259 [H]