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The map label for this gene is mtgA [H]

Identifier: 146337688

GI number: 146337688

Start: 571876

End: 572547

Strand: Direct

Name: mtgA [H]

Synonym: BRADO0556

Alternate gene names: 146337688

Gene position: 571876-572547 (Clockwise)

Preceding gene: 146337685

Following gene: 146337689

Centisome position: 7.67

GC content: 69.94

Gene sequence:

>672_bases
TTGCGTACCGTCAGAGCCATCCTCCTGGTCGTCGTGCTGGTGCTGCTGGTGCCCTACATCCTGACGCCGTTCTATGCGCT
GGGTCACCCGGTCTCGAGCCTGATGCTGTGGCGGACGGTGACCGGCCGGCCGGTCGAGCGGCGCTGGATCGACCTCGCGG
CGATGTCGCCGTATCTGCCGCGCTCGGTCGTGGCAGCCGAGGACGCCAAATTCTGCACCCATCATGGCATCGACTGGGGG
GCGCTGCGCGAGGTCATGGACGATGCCGAGGATGGCGAGGTCTCGCGGGGCGGCTCGACCATCACCCAGCAGGTCGCCAA
GAACCTGTTCCTGTGGCAGGGCCGCAGCTATGTGCGCAAGGCGCTGGAGCTGCCGCTGGCGCTGTGGATCGATCTCGTCC
TGCCCAAGCGGCGCGTTCTCGAGATCTACCTCAACATCGCCGAGCTGGGCCCGGCCGGCCAGTTCGGGGTGGAGGCCGGC
GCGAATTACGCGTTCAACCGCTCGGCGGCGGGCCTCGGCCCGCGTGAGGCGGCGCTGATGGCCTCGATCCTGCCGAATCC
GGTCCGGCGCAGCGCCCGGACGCCGGGTCCCGGCGTGCGGCGGTTGTCGGCGACCTATCTGGTGCGGGCCCAGGCCCAGG
GCCTGCAGACCTGCTGGGGAGAGCGCCGTTGA

Upstream 100 bases:

>100_bases
GCCGCAAGCGCGGAAAAAACCAGGAAACCACGTGGAGATATCGGATAATCCGGGCCCATCGGCTGCCCCGACGGCGGTCC
AACCCGAGCGACGCCTGTCC

Downstream 100 bases:

>100_bases
GGTCCGACAGGTTACGAATTTTGGCCAAAAATGCCCCGGAGAGCCCTAGCCATGCCGGACCCCTTCCTCTATAAGCGCGG
CCTTGATCGGCATCCGGGCT

Product: monofunctional biosynthetic peptidoglycan transglycosylase

Products: NA

Alternate protein names: Monofunctional TGase [H]

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MRTVRAILLVVVLVLLVPYILTPFYALGHPVSSLMLWRTVTGRPVERRWIDLAAMSPYLPRSVVAAEDAKFCTHHGIDWG
ALREVMDDAEDGEVSRGGSTITQQVAKNLFLWQGRSYVRKALELPLALWIDLVLPKRRVLEIYLNIAELGPAGQFGVEAG
ANYAFNRSAAGLGPREAALMASILPNPVRRSARTPGPGVRRLSATYLVRAQAQGLQTCWGERR

Sequences:

>Translated_223_residues
MRTVRAILLVVVLVLLVPYILTPFYALGHPVSSLMLWRTVTGRPVERRWIDLAAMSPYLPRSVVAAEDAKFCTHHGIDWG
ALREVMDDAEDGEVSRGGSTITQQVAKNLFLWQGRSYVRKALELPLALWIDLVLPKRRVLEIYLNIAELGPAGQFGVEAG
ANYAFNRSAAGLGPREAALMASILPNPVRRSARTPGPGVRRLSATYLVRAQAQGLQTCWGERR
>Mature_223_residues
MRTVRAILLVVVLVLLVPYILTPFYALGHPVSSLMLWRTVTGRPVERRWIDLAAMSPYLPRSVVAAEDAKFCTHHGIDWG
ALREVMDDAEDGEVSRGGSTITQQVAKNLFLWQGRSYVRKALELPLALWIDLVLPKRRVLEIYLNIAELGPAGQFGVEAG
ANYAFNRSAAGLGPREAALMASILPNPVRRSARTPGPGVRRLSATYLVRAQAQGLQTCWGERR

Specific function: Cell wall formation [H]

COG id: COG0744

COG function: function code M; Membrane carboxypeptidase (penicillin-binding protein)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 51 family [H]

Homologues:

Organism=Escherichia coli, GI1789601, Length=214, Percent_Identity=42.5233644859813, Blast_Score=140, Evalue=8e-35,
Organism=Escherichia coli, GI87082258, Length=139, Percent_Identity=36.6906474820144, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI1786343, Length=143, Percent_Identity=34.2657342657343, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001264
- InterPro:   IPR011812 [H]

Pfam domain/function: PF00912 Transgly [H]

EC number: 2.4.2.- [C]

Molecular weight: Translated: 24671; Mature: 24671

Theoretical pI: Translated: 10.41; Mature: 10.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTVRAILLVVVLVLLVPYILTPFYALGHPVSSLMLWRTVTGRPVERRWIDLAAMSPYLP
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCC
RSVVAAEDAKFCTHHGIDWGALREVMDDAEDGEVSRGGSTITQQVAKNLFLWQGRSYVRK
HHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHH
ALELPLALWIDLVLPKRRVLEIYLNIAELGPAGQFGVEAGANYAFNRSAAGLGPREAALM
HHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCHHCCCCCCCCCCCCCCCHHHHHHH
ASILPNPVRRSARTPGPGVRRLSATYLVRAQAQGLQTCWGERR
HHHCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRTVRAILLVVVLVLLVPYILTPFYALGHPVSSLMLWRTVTGRPVERRWIDLAAMSPYLP
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCC
RSVVAAEDAKFCTHHGIDWGALREVMDDAEDGEVSRGGSTITQQVAKNLFLWQGRSYVRK
HHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHH
ALELPLALWIDLVLPKRRVLEIYLNIAELGPAGQFGVEAGANYAFNRSAAGLGPREAALM
HHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCHHCCCCCCCCCCCCCCCHHHHHHH
ASILPNPVRRSARTPGPGVRRLSATYLVRAQAQGLQTCWGERR
HHHCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]