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The map label for this gene is 146337526

Identifier: 146337526

GI number: 146337526

Start: 385555

End: 386547

Strand: Direct

Name: 146337526

Synonym: BRADO0380

Alternate gene names: NA

Gene position: 385555-386547 (Clockwise)

Preceding gene: 146337518

Following gene: 146337529

Centisome position: 5.17

GC content: 67.27

Gene sequence:

>993_bases
TTGCTGCGCCGTTCCAGGACCTATTCCGGCCCCGTCACCGACCATTTCGACGGCAAGCGCTTCTACGATCCCGACGGCGT
TCCGCCCAAATCCCTCGCCCAGGTGCTGCGCTGGCAGTTCGACCGCAACGGCAAGCGCTCGCGCTGGCCCGCCTGGGCGC
CGAGCCCGCATGCGGATACCCCGCCGCACCGGATCGAGGGCGAGACGGTGCGGCTGTCGTTCATCGGCCATGCCAGCTGG
CTGGTCCAGACCGGCGGGCTGAACATTCTGATCGATCCCGTCTGGTCGGAGCGGGTCTCGCCGCTCTCGTTCGCGGGTCC
GAGGCGGCACAACGATCCCGGCATCGCCTTCGAGGCGCTGCCGCATATCGACGTCGTGCTGGTCTCGCACGGGCATTACG
ATCATCTCGACATCCGCACGCTTTCGAAGCTGACGGCGCGTTTCGCGCCGCGCGTGGTGACGCCGCTCGGCAACGATCTC
ACCATGACCGATGCCGATGCGAAGATTCGCGCCGAGGCCTATGACTGGCACGACCGCGTGACGCTCAACGACGAGGTCGC
GGTCACGCTGGTACCGACCCGGCACTGGACCGCGCGCGGCATCTTCGATCGCAACAAGGCGCTGTGGGCGAGCTTCGTGC
TGGAGACCCCGCGCGGCAGGCTCTACATCGTCTGCGATTCCGGCTACGGCACGGGCAAGCATTTCCGCCGGGTCGCCGAA
GCGCATGCGCCGCTGCGGCTCGCAATCCTGCCGATCGGCGCCTATGAGCCGCGCTGGTTCATGCGCGACCAGCACATGAA
CCCCGAGGATGCCGTGCAGGCGTTACAAGATTGCGGCGCCGAGACCGCGCTGGCGCATCATCACGGCACGTTCCAGCTGA
CGGACGAAGCGATCGACGCGCCTGTCCACGCGCTGCATGCGGCGCTTGATTCCGCCGGCATTCCACGCGAGCGGTTCAGC
GTGCTGAAGCCGGGGCAGGTGGTGGAGATCTAA

Upstream 100 bases:

>100_bases
CGGAAAAGTCAAGGAAACTTGCGCGCTGCGCGCCGTTGCCGGACCCAGAGTGGCGCCTTACCTCTTGCGCTAGTTTAGCT
TTCCCATTGCGAGGACACCC

Downstream 100 bases:

>100_bases
CTCGCCGCCGCTACAAAACAGGTGTCGTCCCGGCCTTGAGCCGGGACCCATAACCACCGAACGTAATGTTGCGAAGGCTA
GTTGCCCCATTTCGCGCGAC

Product: putative metallo-hydrolase/oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MLRRSRTYSGPVTDHFDGKRFYDPDGVPPKSLAQVLRWQFDRNGKRSRWPAWAPSPHADTPPHRIEGETVRLSFIGHASW
LVQTGGLNILIDPVWSERVSPLSFAGPRRHNDPGIAFEALPHIDVVLVSHGHYDHLDIRTLSKLTARFAPRVVTPLGNDL
TMTDADAKIRAEAYDWHDRVTLNDEVAVTLVPTRHWTARGIFDRNKALWASFVLETPRGRLYIVCDSGYGTGKHFRRVAE
AHAPLRLAILPIGAYEPRWFMRDQHMNPEDAVQALQDCGAETALAHHHGTFQLTDEAIDAPVHALHAALDSAGIPRERFS
VLKPGQVVEI

Sequences:

>Translated_330_residues
MLRRSRTYSGPVTDHFDGKRFYDPDGVPPKSLAQVLRWQFDRNGKRSRWPAWAPSPHADTPPHRIEGETVRLSFIGHASW
LVQTGGLNILIDPVWSERVSPLSFAGPRRHNDPGIAFEALPHIDVVLVSHGHYDHLDIRTLSKLTARFAPRVVTPLGNDL
TMTDADAKIRAEAYDWHDRVTLNDEVAVTLVPTRHWTARGIFDRNKALWASFVLETPRGRLYIVCDSGYGTGKHFRRVAE
AHAPLRLAILPIGAYEPRWFMRDQHMNPEDAVQALQDCGAETALAHHHGTFQLTDEAIDAPVHALHAALDSAGIPRERFS
VLKPGQVVEI
>Mature_330_residues
MLRRSRTYSGPVTDHFDGKRFYDPDGVPPKSLAQVLRWQFDRNGKRSRWPAWAPSPHADTPPHRIEGETVRLSFIGHASW
LVQTGGLNILIDPVWSERVSPLSFAGPRRHNDPGIAFEALPHIDVVLVSHGHYDHLDIRTLSKLTARFAPRVVTPLGNDL
TMTDADAKIRAEAYDWHDRVTLNDEVAVTLVPTRHWTARGIFDRNKALWASFVLETPRGRLYIVCDSGYGTGKHFRRVAE
AHAPLRLAILPIGAYEPRWFMRDQHMNPEDAVQALQDCGAETALAHHHGTFQLTDEAIDAPVHALHAALDSAGIPRERFS
VLKPGQVVEI

Specific function: Unknown

COG id: COG2220

COG function: function code R; Predicted Zn-dependent hydrolases of the beta-lactamase fold

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To K.pneumoniae romA [H]

Homologues:

Organism=Homo sapiens, GI170932483, Length=260, Percent_Identity=37.6923076923077, Blast_Score=179, Evalue=4e-45,
Organism=Homo sapiens, GI170932481, Length=260, Percent_Identity=37.6923076923077, Blast_Score=179, Evalue=4e-45,
Organism=Caenorhabditis elegans, GI17543100, Length=269, Percent_Identity=33.8289962825279, Blast_Score=162, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI17543102, Length=269, Percent_Identity=33.8289962825279, Blast_Score=161, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI25148824, Length=269, Percent_Identity=33.8289962825279, Blast_Score=161, Evalue=5e-40,
Organism=Caenorhabditis elegans, GI17543104, Length=268, Percent_Identity=32.4626865671642, Blast_Score=147, Evalue=6e-36,
Organism=Saccharomyces cerevisiae, GI6325154, Length=247, Percent_Identity=31.1740890688259, Blast_Score=121, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 37078; Mature: 37078

Theoretical pI: Translated: 7.62; Mature: 7.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRRSRTYSGPVTDHFDGKRFYDPDGVPPKSLAQVLRWQFDRNGKRSRWPAWAPSPHADT
CCCCCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
PPHRIEGETVRLSFIGHASWLVQTGGLNILIDPVWSERVSPLSFAGPRRHNDPGIAFEAL
CCCCCCCCEEEEEEEECEEEEEEECCCEEEECCCHHCCCCCCCCCCCCCCCCCCEEEEEC
PHIDVVLVSHGHYDHLDIRTLSKLTARFAPRVVTPLGNDLTMTDADAKIRAEAYDWHDRV
CCEEEEEEECCCCCCCHHHHHHHHHHHHCCEEECCCCCCEEEECCCCEEEEEEECCCCEE
TLNDEVAVTLVPTRHWTARGIFDRNKALWASFVLETPRGRLYIVCDSGYGTGKHFRRVAE
EECCCEEEEEEECCCCEECCCCCCCHHEEEEEEEECCCCEEEEEEECCCCCHHHHHHHHH
AHAPLRLAILPIGAYEPRWFMRDQHMNPEDAVQALQDCGAETALAHHHGTFQLTDEAIDA
HCCCEEEEEEECCCCCCCEEECCCCCCHHHHHHHHHHCCCHHHHHHCCCEEEECHHHHHH
PVHALHAALDSAGIPRERFSVLKPGQVVEI
HHHHHHHHHHHCCCCHHHHHHCCCCCEEEC
>Mature Secondary Structure
MLRRSRTYSGPVTDHFDGKRFYDPDGVPPKSLAQVLRWQFDRNGKRSRWPAWAPSPHADT
CCCCCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
PPHRIEGETVRLSFIGHASWLVQTGGLNILIDPVWSERVSPLSFAGPRRHNDPGIAFEAL
CCCCCCCCEEEEEEEECEEEEEEECCCEEEECCCHHCCCCCCCCCCCCCCCCCCEEEEEC
PHIDVVLVSHGHYDHLDIRTLSKLTARFAPRVVTPLGNDLTMTDADAKIRAEAYDWHDRV
CCEEEEEEECCCCCCCHHHHHHHHHHHHCCEEECCCCCCEEEECCCCEEEEEEECCCCEE
TLNDEVAVTLVPTRHWTARGIFDRNKALWASFVLETPRGRLYIVCDSGYGTGKHFRRVAE
EECCCEEEEEEECCCCEECCCCCCCHHEEEEEEEECCCCEEEEEEECCCCCHHHHHHHHH
AHAPLRLAILPIGAYEPRWFMRDQHMNPEDAVQALQDCGAETALAHHHGTFQLTDEAIDA
HCCCEEEEEEECCCCCCCEEECCCCCCHHHHHHHHHHCCCHHHHHHCCCEEEECHHHHHH
PVHALHAALDSAGIPRERFSVLKPGQVVEI
HHHHHHHHHHHCCCCHHHHHHCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]