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The map label for this gene is gcp [H]

Identifier: 146337459

GI number: 146337459

Start: 315949

End: 317016

Strand: Direct

Name: gcp [H]

Synonym: BRADO0302

Alternate gene names: 146337459

Gene position: 315949-317016 (Clockwise)

Preceding gene: 146337454

Following gene: 146337460

Centisome position: 4.24

GC content: 70.6

Gene sequence:

>1068_bases
GTGCTCGGCATCGAGACCACCTGCGACGAGACCGCCGCGGCGGTGGTCTCCAGGGATTCGGACGGCAAGGGGCATATCCT
CTCGAATGTGGTGCGCTCGCAGACCGACGAGCACGCGATCTATGGCGGCGTGGTTCCCGAGATCGCGGCGCGTGCCCATG
TCGAGATGCTCGATCATCTCATCGACGCCGCGATGCGCGAAGCCGGCATCGATTATGCCGCGCTGTCGGGCGTCGCCGCG
GCCGCCGGGCCCGGCCTGATCGGCGGCGTCATCGTCGGTCTGACCACCGCCAAGGCGATCGCGTTGGTGCACGACACGCC
GCTGATCGCCGTCAACCATCTCGAGGCGCATGCGCTGACGCCGCGCCTCACCGATGCAATCGACTTTCCCTACTGCCTGT
TCCTGGCCTCCGGCGGCCACACCCAGATCGTCGCGGTGGCCGGCGTCGGCGATTACGTCAGGCTCGGCACCACGGTCGAC
GACGCGATGGGCGAGGCGTTCGACAAGGTCGCGAAGATGCTCGGCCTGCCCTATCCGGGCGGCCCGCAAGTGGAGCAGGC
CGCGCGCAACGGCGACGCCACGCGGTTCGCGTTTCCGCGTCCGATGCAGGGCCGAAGCGACGCGAATTTCTCGCTGTCCG
GATTGAAGACTGCCGTGCGCAACGAGATCGGCCGCCTGGAGAGCGTCAGCGAGCAGGATGTCGCCGATCTCTGCGCCAGC
TTCCAGGCCGCGGTGCTGGAGTCCACCGCCGACCGCCTGCGCGTCGGGCTCGACCTGTTCGAGCAGCGCTTCGGCGCGCC
GACCGCGCTGGTCGCGGCCGGCGGCGTCGCCGCCAACCAGGCGATCCGCGGAGCGCTCGACGATGTCGCGCAAGCCGCCG
GCACCCGCCTGATCGTGCCGCCGCCCGCGCTGTGCACCGACAACGGCGCGATGATCGCCTGGGCCGGCGCCGAGCGCCTT
GCGCTCGGCCTGGTCGACGGCATGGACGCACCGCCCCGCGCCCGCTGGCTGCTGGACGCCAATGCGCAAGTGCCCGGCAA
GTTCGCGAACACGCGCGCGGGGTTTTGA

Upstream 100 bases:

>100_bases
ACGGCGTGGTGATTGCACCTGGCGACCTCGTGATGTTAGGCGGATCCGCGCACACATAATGACCAAAGGGTTGAGATTGG
GTAACGACTCGCAAACGCTC

Downstream 100 bases:

>100_bases
GAGCGTGCCGAAGCTGCTCCCTTACGCCACACTCCAGCGCGAGGCACGTCCGAGCCTCTCCCCACGCGTGGCGCCTCTCC
GCGCGATCGGTGGGTGGGGC

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease [H]

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MLGIETTCDETAAAVVSRDSDGKGHILSNVVRSQTDEHAIYGGVVPEIAARAHVEMLDHLIDAAMREAGIDYAALSGVAA
AAGPGLIGGVIVGLTTAKAIALVHDTPLIAVNHLEAHALTPRLTDAIDFPYCLFLASGGHTQIVAVAGVGDYVRLGTTVD
DAMGEAFDKVAKMLGLPYPGGPQVEQAARNGDATRFAFPRPMQGRSDANFSLSGLKTAVRNEIGRLESVSEQDVADLCAS
FQAAVLESTADRLRVGLDLFEQRFGAPTALVAAGGVAANQAIRGALDDVAQAAGTRLIVPPPALCTDNGAMIAWAGAERL
ALGLVDGMDAPPRARWLLDANAQVPGKFANTRAGF

Sequences:

>Translated_355_residues
MLGIETTCDETAAAVVSRDSDGKGHILSNVVRSQTDEHAIYGGVVPEIAARAHVEMLDHLIDAAMREAGIDYAALSGVAA
AAGPGLIGGVIVGLTTAKAIALVHDTPLIAVNHLEAHALTPRLTDAIDFPYCLFLASGGHTQIVAVAGVGDYVRLGTTVD
DAMGEAFDKVAKMLGLPYPGGPQVEQAARNGDATRFAFPRPMQGRSDANFSLSGLKTAVRNEIGRLESVSEQDVADLCAS
FQAAVLESTADRLRVGLDLFEQRFGAPTALVAAGGVAANQAIRGALDDVAQAAGTRLIVPPPALCTDNGAMIAWAGAERL
ALGLVDGMDAPPRARWLLDANAQVPGKFANTRAGF
>Mature_355_residues
MLGIETTCDETAAAVVSRDSDGKGHILSNVVRSQTDEHAIYGGVVPEIAARAHVEMLDHLIDAAMREAGIDYAALSGVAA
AAGPGLIGGVIVGLTTAKAIALVHDTPLIAVNHLEAHALTPRLTDAIDFPYCLFLASGGHTQIVAVAGVGDYVRLGTTVD
DAMGEAFDKVAKMLGLPYPGGPQVEQAARNGDATRFAFPRPMQGRSDANFSLSGLKTAVRNEIGRLESVSEQDVADLCAS
FQAAVLESTADRLRVGLDLFEQRFGAPTALVAAGGVAANQAIRGALDDVAQAAGTRLIVPPPALCTDNGAMIAWAGAERL
ALGLVDGMDAPPRARWLLDANAQVPGKFANTRAGF

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family [H]

Homologues:

Organism=Homo sapiens, GI116812636, Length=366, Percent_Identity=35.792349726776, Blast_Score=210, Evalue=1e-54,
Organism=Homo sapiens, GI8923380, Length=326, Percent_Identity=28.8343558282209, Blast_Score=110, Evalue=2e-24,
Organism=Escherichia coli, GI1789445, Length=346, Percent_Identity=44.2196531791908, Blast_Score=267, Evalue=7e-73,
Organism=Caenorhabditis elegans, GI17557464, Length=326, Percent_Identity=34.6625766871166, Blast_Score=163, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI71995670, Length=332, Percent_Identity=29.8192771084337, Blast_Score=111, Evalue=7e-25,
Organism=Saccharomyces cerevisiae, GI6320099, Length=374, Percent_Identity=29.144385026738, Blast_Score=149, Evalue=8e-37,
Organism=Saccharomyces cerevisiae, GI6322891, Length=305, Percent_Identity=26.2295081967213, Blast_Score=81, Evalue=2e-16,
Organism=Drosophila melanogaster, GI20129063, Length=342, Percent_Identity=34.7953216374269, Blast_Score=189, Evalue=2e-48,
Organism=Drosophila melanogaster, GI21357207, Length=334, Percent_Identity=28.1437125748503, Blast_Score=114, Evalue=7e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017860
- InterPro:   IPR017861 [H]

Pfam domain/function: PF00814 Peptidase_M22 [H]

EC number: =3.4.24.57 [H]

Molecular weight: Translated: 36724; Mature: 36724

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGIETTCDETAAAVVSRDSDGKGHILSNVVRSQTDEHAIYGGVVPEIAARAHVEMLDHL
CCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCEECCCHHHHHHHHHHHHHHHH
IDAAMREAGIDYAALSGVAAAAGPGLIGGVIVGLTTAKAIALVHDTPLIAVNHLEAHALT
HHHHHHHHCCCHHHHHCHHHHCCCCHHHHHHHHHHHHHHEEEEECCCEEEEECCHHHHCC
PRLTDAIDFPYCLFLASGGHTQIVAVAGVGDYVRLGTTVDDAMGEAFDKVAKMLGLPYPG
CHHHHHHCCCEEEEEECCCCEEEEEEECCCCCEEECCCHHHHHHHHHHHHHHHHCCCCCC
GPQVEQAARNGDATRFAFPRPMQGRSDANFSLSGLKTAVRNEIGRLESVSEQDVADLCAS
CCCHHHHHCCCCCCEEECCCCCCCCCCCCEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
FQAAVLESTADRLRVGLDLFEQRFGAPTALVAAGGVAANQAIRGALDDVAQAAGTRLIVP
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCEEEEC
PPALCTDNGAMIAWAGAERLALGLVDGMDAPPRARWLLDANAQVPGKFANTRAGF
CCCCCCCCCCEEEECCCHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLGIETTCDETAAAVVSRDSDGKGHILSNVVRSQTDEHAIYGGVVPEIAARAHVEMLDHL
CCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCEECCCHHHHHHHHHHHHHHHH
IDAAMREAGIDYAALSGVAAAAGPGLIGGVIVGLTTAKAIALVHDTPLIAVNHLEAHALT
HHHHHHHHCCCHHHHHCHHHHCCCCHHHHHHHHHHHHHHEEEEECCCEEEEECCHHHHCC
PRLTDAIDFPYCLFLASGGHTQIVAVAGVGDYVRLGTTVDDAMGEAFDKVAKMLGLPYPG
CHHHHHHCCCEEEEEECCCCEEEEEEECCCCCEEECCCHHHHHHHHHHHHHHHHCCCCCC
GPQVEQAARNGDATRFAFPRPMQGRSDANFSLSGLKTAVRNEIGRLESVSEQDVADLCAS
CCCHHHHHCCCCCCEEECCCCCCCCCCCCEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
FQAAVLESTADRLRVGLDLFEQRFGAPTALVAAGGVAANQAIRGALDDVAQAAGTRLIVP
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCEEEEC
PPALCTDNGAMIAWAGAERLALGLVDGMDAPPRARWLLDANAQVPGKFANTRAGF
CCCCCCCCCCEEEECCCHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA