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The map label for this gene is dapL [H]

Identifier: 146337392

GI number: 146337392

Start: 239466

End: 240680

Strand: Reverse

Name: dapL [H]

Synonym: BRADO0225

Alternate gene names: 146337392

Gene position: 240680-239466 (Counterclockwise)

Preceding gene: 146337394

Following gene: 146337391

Centisome position: 3.23

GC content: 68.72

Gene sequence:

>1215_bases
ATGGCAATGACCGCTTCATCCCCCGCGCCCGCTGGCGCCAGCCATTCGGAGAGCGAACGCTCGCCGTTTGCGCGGCTGAA
CGAGCTGCTCGCCCCGTATTCTCCCGGCAAACCGATGATCACGCTCGCGGTCGGCGAGCCGCAGCATCCGGTGCCGGATT
TCGTCGGTCCCGTGCTGGCGCAGCACATCGCCGATTTCGGCCGCTACCCGGCCGCCAAAGGCATCGAGCCGTTTCGCAAG
GCGGCGGCCGCCTGGCTGTCGCGCCGATTCGCGCTGCCGCGGCCGATCGATCCCGAGCACGAGATCCTGGTCCTGAACGG
CAGCCGCGAGGGCCTGTTCTTCGCCGCGCATGCCGCGCTCCGCCATGTCGGCCCGCGCCGCGGCAGACCGGCGATCCTGA
TGCCGAACCCGTTCTATCCGGTGTACGGCGTCGGCGCCCGCACGGCGGGCTGCGATTCCATCTATCTGCCGACAACGCGC
GACAACGGCTTCCTGCCGGACCTCGATGCGATCGACGAGGCGACCTTGGCGCGCACCGTCGCGTTCTACATCGCGACGCC
GGCCAATCCGCAAGGCTCGGTGGCTTCAGCGGACTACATGCGCAAGCTGGTCCAGCTCGCCAAGACTTACGGCTTCCTGA
TCTTCAGCGACGAATGCTATTCGGAGATCTACACCAAGACGGCGCCCGGCAGCATGCTCGAGCATGCCGGTCCCGACTAC
ACCAATGTCGTCGCGTTCCAGTCGCTGTCGAAGCGCTCCAACGTGCCGGGCATGCGCATCGGCTTCGCCGCCGGCGATCG
CCGCTTCCTCGCCGCCTTCCACGAGCTGCGCAATGTCGCCGCACCGCAGGTGCCGGTGCCGCTGCAGCACGTCGCGGTCG
CGGCCTATGCCGACGAGGATCACGTCGAGGCGAACCGGCGGCTGTACCGTGCCAAGTTCGACCTCGCCGACCAGATCATC
GGCAATCGCTACGGCTACACGCGGCCCGACGGCGGCTTCTGCGTCTGGCTCGACGTCGCGGACCGCGGCGGCGACGCAGA
CGTGGCGCTGCGGCTCTATCGTGACGCCGGCGTGCGCGTGGTGCCCGGCAGCTATCTGGCGCGGCCGCAACCCGACGGCT
TCAATCCGGGCGTCGGCTATATCAGGCTGGCGCTGGTGGCCGATGCCGCCTCGACCGGCGAGGCGCTGCACCGGCTGGTC
GAGACTCTCGGATAA

Upstream 100 bases:

>100_bases
ATGGTTAATCGCGTCTTAACCTCGCCCCACCTATGGTGACCGCAAAGGCACCGGTTCATGGGCGATCGGCGGCTTCCACT
GGTTTGGCGCGCGTTTACGT

Downstream 100 bases:

>100_bases
TCGCGGGGCGGATGCGGATGCCGGCGATCGAACGAGTCATTCCCCTGGTCAACCACCTGCCGACGTCGCTGCGCGACGCG
CTGGTGCGGCGGCTGCGCGA

Product: putative aminotransferase (aatC)

Products: NA

Alternate protein names: DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase [H]

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MAMTASSPAPAGASHSESERSPFARLNELLAPYSPGKPMITLAVGEPQHPVPDFVGPVLAQHIADFGRYPAAKGIEPFRK
AAAAWLSRRFALPRPIDPEHEILVLNGSREGLFFAAHAALRHVGPRRGRPAILMPNPFYPVYGVGARTAGCDSIYLPTTR
DNGFLPDLDAIDEATLARTVAFYIATPANPQGSVASADYMRKLVQLAKTYGFLIFSDECYSEIYTKTAPGSMLEHAGPDY
TNVVAFQSLSKRSNVPGMRIGFAAGDRRFLAAFHELRNVAAPQVPVPLQHVAVAAYADEDHVEANRRLYRAKFDLADQII
GNRYGYTRPDGGFCVWLDVADRGGDADVALRLYRDAGVRVVPGSYLARPQPDGFNPGVGYIRLALVADAASTGEALHRLV
ETLG

Sequences:

>Translated_404_residues
MAMTASSPAPAGASHSESERSPFARLNELLAPYSPGKPMITLAVGEPQHPVPDFVGPVLAQHIADFGRYPAAKGIEPFRK
AAAAWLSRRFALPRPIDPEHEILVLNGSREGLFFAAHAALRHVGPRRGRPAILMPNPFYPVYGVGARTAGCDSIYLPTTR
DNGFLPDLDAIDEATLARTVAFYIATPANPQGSVASADYMRKLVQLAKTYGFLIFSDECYSEIYTKTAPGSMLEHAGPDY
TNVVAFQSLSKRSNVPGMRIGFAAGDRRFLAAFHELRNVAAPQVPVPLQHVAVAAYADEDHVEANRRLYRAKFDLADQII
GNRYGYTRPDGGFCVWLDVADRGGDADVALRLYRDAGVRVVPGSYLARPQPDGFNPGVGYIRLALVADAASTGEALHRLV
ETLG
>Mature_403_residues
AMTASSPAPAGASHSESERSPFARLNELLAPYSPGKPMITLAVGEPQHPVPDFVGPVLAQHIADFGRYPAAKGIEPFRKA
AAAWLSRRFALPRPIDPEHEILVLNGSREGLFFAAHAALRHVGPRRGRPAILMPNPFYPVYGVGARTAGCDSIYLPTTRD
NGFLPDLDAIDEATLARTVAFYIATPANPQGSVASADYMRKLVQLAKTYGFLIFSDECYSEIYTKTAPGSMLEHAGPDYT
NVVAFQSLSKRSNVPGMRIGFAAGDRRFLAAFHELRNVAAPQVPVPLQHVAVAAYADEDHVEANRRLYRAKFDLADQIIG
NRYGYTRPDGGFCVWLDVADRGGDADVALRLYRDAGVRVVPGSYLARPQPDGFNPGVGYIRLALVADAASTGEALHRLVE
TLG

Specific function: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788722, Length=371, Percent_Identity=26.9541778975741, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1788627, Length=373, Percent_Identity=25.201072386059, Blast_Score=82, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17567663, Length=409, Percent_Identity=21.760391198044, Blast_Score=72, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR019881
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.83 [H]

Molecular weight: Translated: 43729; Mature: 43598

Theoretical pI: Translated: 7.72; Mature: 7.72

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAMTASSPAPAGASHSESERSPFARLNELLAPYSPGKPMITLAVGEPQHPVPDFVGPVLA
CCCCCCCCCCCCCCCCCHHCCHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHH
QHIADFGRYPAAKGIEPFRKAAAAWLSRRFALPRPIDPEHEILVLNGSREGLFFAAHAAL
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCEEHHHHHHH
RHVGPRRGRPAILMPNPFYPVYGVGARTAGCDSIYLPTTRDNGFLPDLDAIDEATLARTV
HHCCCCCCCCEEECCCCCCCEEECCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHEE
AFYIATPANPQGSVASADYMRKLVQLAKTYGFLIFSDECYSEIYTKTAPGSMLEHAGPDY
EEEEECCCCCCCCCHHHHHHHHHHHHHHHHCEEEECHHHHHHHHHCCCCCHHHHHCCCCH
TNVVAFQSLSKRSNVPGMRIGFAAGDRRFLAAFHELRNVAAPQVPVPLQHVAVAAYADED
HHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCCHHHEEEEEECCCH
HVEANRRLYRAKFDLADQIIGNRYGYTRPDGGFCVWLDVADRGGDADVALRLYRDAGVRV
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCHHEEEEEECCCCCEE
VPGSYLARPQPDGFNPGVGYIRLALVADAASTGEALHRLVETLG
ECCHHCCCCCCCCCCCCHHHEEEEHHHCCCHHHHHHHHHHHHHC
>Mature Secondary Structure 
AMTASSPAPAGASHSESERSPFARLNELLAPYSPGKPMITLAVGEPQHPVPDFVGPVLA
CCCCCCCCCCCCCCCCHHCCHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHH
QHIADFGRYPAAKGIEPFRKAAAAWLSRRFALPRPIDPEHEILVLNGSREGLFFAAHAAL
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCEEHHHHHHH
RHVGPRRGRPAILMPNPFYPVYGVGARTAGCDSIYLPTTRDNGFLPDLDAIDEATLARTV
HHCCCCCCCCEEECCCCCCCEEECCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHEE
AFYIATPANPQGSVASADYMRKLVQLAKTYGFLIFSDECYSEIYTKTAPGSMLEHAGPDY
EEEEECCCCCCCCCHHHHHHHHHHHHHHHHCEEEECHHHHHHHHHCCCCCHHHHHCCCCH
TNVVAFQSLSKRSNVPGMRIGFAAGDRRFLAAFHELRNVAAPQVPVPLQHVAVAAYADED
HHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCCHHHEEEEEECCCH
HVEANRRLYRAKFDLADQIIGNRYGYTRPDGGFCVWLDVADRGGDADVALRLYRDAGVRV
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCHHEEEEEECCCCCEE
VPGSYLARPQPDGFNPGVGYIRLALVADAASTGEALHRLVETLG
ECCHHCCCCCCCCCCCCHHHEEEEHHHCCCHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA