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The map label for this gene is coaA [H]

Identifier: 146337385

GI number: 146337385

Start: 228946

End: 229902

Strand: Direct

Name: coaA [H]

Synonym: BRADO0218

Alternate gene names: 146337385

Gene position: 228946-229902 (Clockwise)

Preceding gene: 146337384

Following gene: 146337389

Centisome position: 3.07

GC content: 64.16

Gene sequence:

>957_bases
ATGGATATGCGCACCACCGAACAACAATATAATCCGTACCGCGTCTTCACCCGCCAGCAATGGGCCGAGCTGCGCAACGA
CACGCCGATGACGCTCGAGCCCGGCGAGTTCTCCAAGCTGCGCTCGATGCACGACCGCCTCGATCTACAGGAGGTGGAGG
AGATCTATCTGCCGCTGTCGCGACTGCTCTCCATGTATGTCGACGCGGCGCAGCGGCTGTACTACGCGCAGCGTCAGTTC
CTCGGCATCCGCGACCGCAAGATGCCCTACATCATCGGCGTCGCCGGCTCGGTCTCGGTCGGCAAGTCGACCACCGCACG
CGTGCTGCAGGCGCTGCTGACCCGTTGGTCGCCGCGGCCGAAGGTCGACCTCATCACCACCGACGGTTTCCTGTATCCGA
ACGCGGTGCTGGAGCGGCAGGGCCTGATGCAAAAGAAGGGCTTTCCCGAGAGCTATGATTTGCCGCGCCTGCTCGCCTTC
CTCTCCGACATCAAGGCCGGCCGCCACCCGGTGCGCGCGCCGGTGTACTCGCATCTCAGCTACGACATCGTGCCCAACCA
GTGGACCGAGATCGATCAGCCGGACATCCTCATCGTCGAGGGCGTCAACGTGCTGCAGACCGGACCGTTGCCGCGCGACG
GCAAGGCGGTGCCGGTGGTATCCGACTTCTTCGACTTCTCGGTCTATATCGACGCCGAGGAAGCGGTGCTGCGCAGATGG
TACGTCAAGCGCTTCCTGTCGCTGCGCGACACCGCGTTCCACGATCCCCGCTCCTACTTCAACCGTTACGCGCTGCTGTC
GGACGAAGAGGCCACCGCCACCGCGATCGCGATCTGGGAGCGCACCAACCTCGCCAATCTCGAGGACAACATCCTGCCGA
CAAGGCCACGCGCCACCCTGATCCTGAAGAAGGGTGCCGACCACGAGATCGAAACGGTGGCGCTGCGGCGGCTGTGA

Upstream 100 bases:

>100_bases
GGCGGCGCTCGGCAAGCGAACCGGACAATCGGGGCTGGAAGAAAAGGCGTCGCGCAAGACGGAGTAGGGCGCGACGCCGG
GGGAAACGAAGGGCAGCGTC

Downstream 100 bases:

>100_bases
CTTGAAGCGACCAAGCGATTGCGGCATCAGCTAGAGCTGGCGTCTTGCTGTTTGATGTGATGACCCCGGTGCTAAGGCTT
GCGCCGCTTCAACCTCTCCC

Product: pantothenate kinase

Products: NA

Alternate protein names: Pantothenic acid kinase [H]

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MDMRTTEQQYNPYRVFTRQQWAELRNDTPMTLEPGEFSKLRSMHDRLDLQEVEEIYLPLSRLLSMYVDAAQRLYYAQRQF
LGIRDRKMPYIIGVAGSVSVGKSTTARVLQALLTRWSPRPKVDLITTDGFLYPNAVLERQGLMQKKGFPESYDLPRLLAF
LSDIKAGRHPVRAPVYSHLSYDIVPNQWTEIDQPDILIVEGVNVLQTGPLPRDGKAVPVVSDFFDFSVYIDAEEAVLRRW
YVKRFLSLRDTAFHDPRSYFNRYALLSDEEATATAIAIWERTNLANLEDNILPTRPRATLILKKGADHEIETVALRRL

Sequences:

>Translated_318_residues
MDMRTTEQQYNPYRVFTRQQWAELRNDTPMTLEPGEFSKLRSMHDRLDLQEVEEIYLPLSRLLSMYVDAAQRLYYAQRQF
LGIRDRKMPYIIGVAGSVSVGKSTTARVLQALLTRWSPRPKVDLITTDGFLYPNAVLERQGLMQKKGFPESYDLPRLLAF
LSDIKAGRHPVRAPVYSHLSYDIVPNQWTEIDQPDILIVEGVNVLQTGPLPRDGKAVPVVSDFFDFSVYIDAEEAVLRRW
YVKRFLSLRDTAFHDPRSYFNRYALLSDEEATATAIAIWERTNLANLEDNILPTRPRATLILKKGADHEIETVALRRL
>Mature_318_residues
MDMRTTEQQYNPYRVFTRQQWAELRNDTPMTLEPGEFSKLRSMHDRLDLQEVEEIYLPLSRLLSMYVDAAQRLYYAQRQF
LGIRDRKMPYIIGVAGSVSVGKSTTARVLQALLTRWSPRPKVDLITTDGFLYPNAVLERQGLMQKKGFPESYDLPRLLAF
LSDIKAGRHPVRAPVYSHLSYDIVPNQWTEIDQPDILIVEGVNVLQTGPLPRDGKAVPVVSDFFDFSVYIDAEEAVLRRW
YVKRFLSLRDTAFHDPRSYFNRYALLSDEEATATAIAIWERTNLANLEDNILPTRPRATLILKKGADHEIETVALRRL

Specific function: Coenzyme A (CoA) biosynthesis; first step. [C]

COG id: COG1072

COG function: function code H; Panthothenate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic pantothenate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1790409, Length=317, Percent_Identity=55.5205047318612, Blast_Score=350, Evalue=1e-97,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004566
- InterPro:   IPR006083 [H]

Pfam domain/function: PF00485 PRK [H]

EC number: =2.7.1.33 [H]

Molecular weight: Translated: 36752; Mature: 36752

Theoretical pI: Translated: 7.83; Mature: 7.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDMRTTEQQYNPYRVFTRQQWAELRNDTPMTLEPGEFSKLRSMHDRLDLQEVEEIYLPLS
CCCCCCCHHCCCEEEHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHCCHHHHHHHHHHHH
RLLSMYVDAAQRLYYAQRQFLGIRDRKMPYIIGVAGSVSVGKSTTARVLQALLTRWSPRP
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCC
KVDLITTDGFLYPNAVLERQGLMQKKGFPESYDLPRLLAFLSDIKAGRHPVRAPVYSHLS
CEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHCCE
YDIVPNQWTEIDQPDILIVEGVNVLQTGPLPRDGKAVPVVSDFFDFSVYIDAEEAVLRRW
ECCCCCCCCCCCCCCEEEECCCCEEECCCCCCCCCCCCEEHHCCCEEEEECHHHHHHHHH
YVKRFLSLRDTAFHDPRSYFNRYALLSDEEATATAIAIWERTNLANLEDNILPTRPRATL
HHHHHHHHHHHHCCCHHHHHHHEEEECCCCCCEEEEEEEECCCCCCCCCCCCCCCCCEEE
ILKKGADHEIETVALRRL
EEECCCCCCHHHHHHHCC
>Mature Secondary Structure
MDMRTTEQQYNPYRVFTRQQWAELRNDTPMTLEPGEFSKLRSMHDRLDLQEVEEIYLPLS
CCCCCCCHHCCCEEEHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHCCHHHHHHHHHHHH
RLLSMYVDAAQRLYYAQRQFLGIRDRKMPYIIGVAGSVSVGKSTTARVLQALLTRWSPRP
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCC
KVDLITTDGFLYPNAVLERQGLMQKKGFPESYDLPRLLAFLSDIKAGRHPVRAPVYSHLS
CEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHCCE
YDIVPNQWTEIDQPDILIVEGVNVLQTGPLPRDGKAVPVVSDFFDFSVYIDAEEAVLRRW
ECCCCCCCCCCCCCCEEEECCCCEEECCCCCCCCCCCCEEHHCCCEEEEECHHHHHHHHH
YVKRFLSLRDTAFHDPRSYFNRYALLSDEEATATAIAIWERTNLANLEDNILPTRPRATL
HHHHHHHHHHHHCCCHHHHHHHEEEECCCCCCEEEEEEEECCCCCCCCCCCCCCCCCEEE
ILKKGADHEIETVALRRL
EEECCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA