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The map label for this gene is hisE [H]

Identifier: 146337384

GI number: 146337384

Start: 228589

End: 228912

Strand: Direct

Name: hisE [H]

Synonym: BRADO0217

Alternate gene names: 146337384

Gene position: 228589-228912 (Clockwise)

Preceding gene: 146337383

Following gene: 146337385

Centisome position: 3.07

GC content: 63.58

Gene sequence:

>324_bases
ATGTCCCGCTTCACGCTTCACGATCTGGCTGCCATCATCGACGCGCGCGCCGCGGCGGGCGGCGAGTCGTCTTATACGCG
CAAGCTGCTCGACAAGGGTCCGGCGCAGTGCGCCAAGAAAATGGGCGAGGAGGCGGTCGAGACGGTCATTGCCGCCGTCG
GCACTGATCGCGAACATCTGATCTCCGAAAGCGCCGATCTGCTGTTTCATCTGTTGGTGGTGTTGAAGTCGCGCGACGTC
CGGCTCGAAGAGGTCGAGGCGGCGCTCGGCAAGCGAACCGGACAATCGGGGCTGGAAGAAAAGGCGTCGCGCAAGACGGA
GTAG

Upstream 100 bases:

>100_bases
GATGCGGCTCGATCCCTGACGACATTGCGCCGCAAAAATGTTAGATGAACGCGGGTCCGGCCGCCTTGGGAACGGACCTG
CGTGTCCTGAGAACTGGCTG

Downstream 100 bases:

>100_bases
GGCGCGACGCCGGGGGAAACGAAGGGCAGCGTCATGGATATGCGCACCACCGAACAACAATATAATCCGTACCGCGTCTT
CACCCGCCAGCAATGGGCCG

Product: phosphoribosyl-ATP pyrophosphatase

Products: NA

Alternate protein names: PRA-PH 1 [H]

Number of amino acids: Translated: 107; Mature: 106

Protein sequence:

>107_residues
MSRFTLHDLAAIIDARAAAGGESSYTRKLLDKGPAQCAKKMGEEAVETVIAAVGTDREHLISESADLLFHLLVVLKSRDV
RLEEVEAALGKRTGQSGLEEKASRKTE

Sequences:

>Translated_107_residues
MSRFTLHDLAAIIDARAAAGGESSYTRKLLDKGPAQCAKKMGEEAVETVIAAVGTDREHLISESADLLFHLLVVLKSRDV
RLEEVEAALGKRTGQSGLEEKASRKTE
>Mature_106_residues
SRFTLHDLAAIIDARAAAGGESSYTRKLLDKGPAQCAKKMGEEAVETVIAAVGTDREHLISESADLLFHLLVVLKSRDVR
LEEVEAALGKRTGQSGLEEKASRKTE

Specific function: Histidine biosynthesis; second step. Histidine biosynthesis; third step. [C]

COG id: COG0140

COG function: function code E; Phosphoribosyl-ATP pyrophosphohydrolase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PRA-PH family [H]

Homologues:

Organism=Escherichia coli, GI2367128, Length=87, Percent_Identity=42.5287356321839, Blast_Score=67, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008179
- InterPro:   IPR021130 [H]

Pfam domain/function: PF01503 PRA-PH [H]

EC number: =3.6.1.31 [H]

Molecular weight: Translated: 11564; Mature: 11433

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRFTLHDLAAIIDARAAAGGESSYTRKLLDKGPAQCAKKMGEEAVETVIAAVGTDREHL
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHH
ISESADLLFHLLVVLKSRDVRLEEVEAALGKRTGQSGLEEKASRKTE
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHCCCC
>Mature Secondary Structure 
SRFTLHDLAAIIDARAAAGGESSYTRKLLDKGPAQCAKKMGEEAVETVIAAVGTDREHL
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHH
ISESADLLFHLLVVLKSRDVRLEEVEAALGKRTGQSGLEEKASRKTE
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA