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The map label for this gene is sppA [C]

Identifier: 146337268

GI number: 146337268

Start: 110415

End: 111395

Strand: Reverse

Name: sppA [C]

Synonym: BRADO0095

Alternate gene names: 146337268

Gene position: 111395-110415 (Counterclockwise)

Preceding gene: 146337269

Following gene: 146337267

Centisome position: 1.49

GC content: 65.44

Gene sequence:

>981_bases
ATGTCGCTTGATTCCGATGTGATCGTCGATCGCCGCAGGCTGCGCCGCAAGCTGACGTTCTGGCGCGTCGTTGCGGTGGT
GATCGCGATCGGCGCCTTGTCAGCGATCGGCCTTGCAATGTCGCCGCGCGGCCGCACGGCGCTGTCGACGTCAGGCTCGA
TTGCCCGCGTCAATATCGAGGGCCTGATCCGTAGCGATCAGGAGCGCGTCGAGGCGCTGGAGCGGCTGGAGAACTCCTCG
GCCGAGGCGGTTATCGTCCATATCAACTCGCCGGGCGGCACCACCGCCGGCTCCGAGCAGCTGTATGACTCGCTGGTGCG
GTTGAAGGCGAAGAAGCCGCTCGTCGTCGTGGTCGAAGGCCTCGCCGCCTCCGGCGGCTATATCGGCGCGATCGCGTCCG
ACCACATCGTCGCGCAGCAGAGCTCGCTGGTGGGATCGATCGGCGTGCTGTTCCAATATCCCAATGTCAGCGAGCTGCTG
AAGACCGTCGGCGTCAAGATCGAGGAGGTGAAGTCCTCGCCGCTGAAGGCCGCGCCGAACGGTTATGAGCCGACCAGTCC
CGAGGCTCGCGCTGCGTTGGATGATCTCGTGAAGGATTCCTACGCCTGGTTCCGGGGGCTGGTGAAGACCCGCCGCAATA
TGGACGACGCGCTGCTGGAGAAGGTTGCCGATGGACGCGTCTTCACCGGCCGGCAGGCGGTCGAGCTGAAGCTGATCGAC
GAGCTCGGCGACGAGAAGACCGCGGTGGCATGGCTCGTCGCCAACAAGAACGTCAAGAAGGACCTTCCGGTGCGCGACTA
CAAGCTCGTGCCGCGTTTTGGCGACCTGACCTTCCTCCGTACGGCGACGTCGATCGCACTGGACGCCGTCGGCCTCTCCG
GGATCGCGCGTCAGATCGAGCGTACCGGTGTGGTCCAGGCGGTCGATCGGGTGGGCCTGGACGGCATGCTGGCCCTCTGG
ACGCCAGCGGCAGGGAATTGA

Upstream 100 bases:

>100_bases
GAGCCTTCCTTTCTTCAAATTGCGCCACGATTGATGTAATCGGATAACGAGATATTCAGGCTGCGGATGCAAAACGCGCC
GAGACCTCCAGGAGCTGTCC

Downstream 100 bases:

>100_bases
ACCCGCCCAGACCATCCTCGCCCCCATCTACCCGCTCCGCGTGTGCCGGTGCGGGTCTCCTGTGCGGTCACGCAAGCCGA
TTCCTGGGCCCGATGAATGA

Product: S49 family peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 325

Protein sequence:

>326_residues
MSLDSDVIVDRRRLRRKLTFWRVVAVVIAIGALSAIGLAMSPRGRTALSTSGSIARVNIEGLIRSDQERVEALERLENSS
AEAVIVHINSPGGTTAGSEQLYDSLVRLKAKKPLVVVVEGLAASGGYIGAIASDHIVAQQSSLVGSIGVLFQYPNVSELL
KTVGVKIEEVKSSPLKAAPNGYEPTSPEARAALDDLVKDSYAWFRGLVKTRRNMDDALLEKVADGRVFTGRQAVELKLID
ELGDEKTAVAWLVANKNVKKDLPVRDYKLVPRFGDLTFLRTATSIALDAVGLSGIARQIERTGVVQAVDRVGLDGMLALW
TPAAGN

Sequences:

>Translated_326_residues
MSLDSDVIVDRRRLRRKLTFWRVVAVVIAIGALSAIGLAMSPRGRTALSTSGSIARVNIEGLIRSDQERVEALERLENSS
AEAVIVHINSPGGTTAGSEQLYDSLVRLKAKKPLVVVVEGLAASGGYIGAIASDHIVAQQSSLVGSIGVLFQYPNVSELL
KTVGVKIEEVKSSPLKAAPNGYEPTSPEARAALDDLVKDSYAWFRGLVKTRRNMDDALLEKVADGRVFTGRQAVELKLID
ELGDEKTAVAWLVANKNVKKDLPVRDYKLVPRFGDLTFLRTATSIALDAVGLSGIARQIERTGVVQAVDRVGLDGMLALW
TPAAGN
>Mature_325_residues
SLDSDVIVDRRRLRRKLTFWRVVAVVIAIGALSAIGLAMSPRGRTALSTSGSIARVNIEGLIRSDQERVEALERLENSSA
EAVIVHINSPGGTTAGSEQLYDSLVRLKAKKPLVVVVEGLAASGGYIGAIASDHIVAQQSSLVGSIGVLFQYPNVSELLK
TVGVKIEEVKSSPLKAAPNGYEPTSPEARAALDDLVKDSYAWFRGLVKTRRNMDDALLEKVADGRVFTGRQAVELKLIDE
LGDEKTAVAWLVANKNVKKDLPVRDYKLVPRFGDLTFLRTATSIALDAVGLSGIARQIERTGVVQAVDRVGLDGMLALWT
PAAGN

Specific function: Digestion Of The Cleaved Signal Peptides. This Activity Is Necessary To Maintain Proper Secretion Of Mature Proteins Across The Membrane. [C]

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S49 family [H]

Homologues:

Organism=Escherichia coli, GI1787527, Length=193, Percent_Identity=32.1243523316062, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1788064, Length=176, Percent_Identity=35.7954545454545, Blast_Score=92, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004635
- InterPro:   IPR002142 [H]

Pfam domain/function: PF01343 Peptidase_S49 [H]

EC number: 3.4.21.-

Molecular weight: Translated: 35010; Mature: 34879

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLDSDVIVDRRRLRRKLTFWRVVAVVIAIGALSAIGLAMSPRGRTALSTSGSIARVNIE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEECCCCCEEEEEHH
GLIRSDQERVEALERLENSSAEAVIVHINSPGGTTAGSEQLYDSLVRLKAKKPLVVVVEG
HHHCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCEEEEEEC
LAASGGYIGAIASDHIVAQQSSLVGSIGVLFQYPNVSELLKTVGVKIEEVKSSPLKAAPN
CCCCCCEEEEECCCHHHHHHHHHHHHHHHEEECCCHHHHHHHHCCCHHHHCCCCCCCCCC
GYEPTSPEARAALDDLVKDSYAWFRGLVKTRRNMDDALLEKVADGRVFTGRQAVELKLID
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCEECCCCEEEEEEHH
ELGDEKTAVAWLVANKNVKKDLPVRDYKLVPRFGDLTFLRTATSIALDAVGLSGIARQIE
HCCCCCCEEEEEEECCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RTGVVQAVDRVGLDGMLALWTPAAGN
HHHHHHHHHHCCCCCEEEEECCCCCC
>Mature Secondary Structure 
SLDSDVIVDRRRLRRKLTFWRVVAVVIAIGALSAIGLAMSPRGRTALSTSGSIARVNIE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEECCCCCEEEEEHH
GLIRSDQERVEALERLENSSAEAVIVHINSPGGTTAGSEQLYDSLVRLKAKKPLVVVVEG
HHHCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCEEEEEEC
LAASGGYIGAIASDHIVAQQSSLVGSIGVLFQYPNVSELLKTVGVKIEEVKSSPLKAAPN
CCCCCCEEEEECCCHHHHHHHHHHHHHHHEEECCCHHHHHHHHCCCHHHHCCCCCCCCCC
GYEPTSPEARAALDDLVKDSYAWFRGLVKTRRNMDDALLEKVADGRVFTGRQAVELKLID
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCEECCCCEEEEEEHH
ELGDEKTAVAWLVANKNVKKDLPVRDYKLVPRFGDLTFLRTATSIALDAVGLSGIARQIE
HCCCCCCEEEEEEECCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RTGVVQAVDRVGLDGMLALWTPAAGN
HHHHHHHHHHCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]