Click here to switch to the map view.

The map label for this gene is exsA [H]

Identifier: 146301738

GI number: 146301738

Start: 4782776

End: 4783588

Strand: Direct

Name: exsA [H]

Synonym: Fjoh_4000

Alternate gene names: 146301738

Gene position: 4782776-4783588 (Clockwise)

Preceding gene: 146301737

Following gene: 146301746

Centisome position: 78.45

GC content: 33.83

Gene sequence:

>813_bases
ATGAACGATTCTAAAATAAATCAGAAAAACTCGCCAATTGCTTATTCCTGTTATTACACACAGAACAGAGAAGGCGAACA
GTTTGCTTCACAGCATGTTTTGAGTTTCCAAATTTCGGGAGTACTGACTCTTAATAACGGCAGTAAAGAATATGTTTTTA
ATCCTGGTGATTTTAGATTCATTAGAAGAAATCAGCTCATAAAATTCATCAAACAACCGGATCCTAATACAGCTTTTCAG
TCTATTTCGATTTATCTCAATCAGGAAGCGCTTCGGGATTATTCTATTCAATACAATCAAAAAACGAGTTTAATTAAAAG
CCCGGAAACAGAAATGGTTCTTCAGTTAAAAGAAGTGCCGTTATTAAAAAGCTTTATGAATTCGCTGATTCCGTACATAA
ACGAAGACCAATTAATTACCGAAGAACTTCAGGCTTTAAAAGTAAATGAAGCTATTACGATTTTACTGCAATGCAATCCG
GAATTAAAAGATATTCTTTTTGATTTTAACGAACCCGGAAAAATTGATCTGGAAGCGTTTATGAAAAAGAATTTCCATTT
TAACGTGCAACTAGATCGTTTTGCGTATTTAACCGGCAGAAGTCTTGCAACTTTTAAAAGGGATTTTCAGCGTATTTTCG
ATATTTCGCCAAGCCGATGGCTCATTCAGAAAAGATTACAGGAAGCGTATTATCAAATTAAAGAAAAAGGAAAAACACCT
TCTGAAGTTTATTTGGAAGTAGGTTTTGAAGATTTATCGCATTTTTCGTTTGCGTTTAAAAAACAGTTTGGAATGCCTCC
TTCTAAAGTTTGA

Upstream 100 bases:

>100_bases
GTGAAAATCTAGATTTTTTAAACATCTTTTATTTAGAATATAATCTATGTTTCTATGTGTTTAAAATATTCTCCAACTTT
AATTTTCATAATTTTGTGAT

Downstream 100 bases:

>100_bases
TTTTTATTTAACCGCAAAGTACGCAAAGGTTTACGCAATCCCGATAGCTATCGGGAGCATTTTTTTTTAATCTCGGAAAG
ACGCGAAGTCGCAAAGTTTT

Product: helix-turn-helix domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MNDSKINQKNSPIAYSCYYTQNREGEQFASQHVLSFQISGVLTLNNGSKEYVFNPGDFRFIRRNQLIKFIKQPDPNTAFQ
SISIYLNQEALRDYSIQYNQKTSLIKSPETEMVLQLKEVPLLKSFMNSLIPYINEDQLITEELQALKVNEAITILLQCNP
ELKDILFDFNEPGKIDLEAFMKKNFHFNVQLDRFAYLTGRSLATFKRDFQRIFDISPSRWLIQKRLQEAYYQIKEKGKTP
SEVYLEVGFEDLSHFSFAFKKQFGMPPSKV

Sequences:

>Translated_270_residues
MNDSKINQKNSPIAYSCYYTQNREGEQFASQHVLSFQISGVLTLNNGSKEYVFNPGDFRFIRRNQLIKFIKQPDPNTAFQ
SISIYLNQEALRDYSIQYNQKTSLIKSPETEMVLQLKEVPLLKSFMNSLIPYINEDQLITEELQALKVNEAITILLQCNP
ELKDILFDFNEPGKIDLEAFMKKNFHFNVQLDRFAYLTGRSLATFKRDFQRIFDISPSRWLIQKRLQEAYYQIKEKGKTP
SEVYLEVGFEDLSHFSFAFKKQFGMPPSKV
>Mature_270_residues
MNDSKINQKNSPIAYSCYYTQNREGEQFASQHVLSFQISGVLTLNNGSKEYVFNPGDFRFIRRNQLIKFIKQPDPNTAFQ
SISIYLNQEALRDYSIQYNQKTSLIKSPETEMVLQLKEVPLLKSFMNSLIPYINEDQLITEELQALKVNEAITILLQCNP
ELKDILFDFNEPGKIDLEAFMKKNFHFNVQLDRFAYLTGRSLATFKRDFQRIFDISPSRWLIQKRLQEAYYQIKEKGKTP
SEVYLEVGFEDLSHFSFAFKKQFGMPPSKV

Specific function: Appears to be required for induction of exoenzyme S synthesis above a low basal level [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018062
- InterPro:   IPR020449
- InterPro:   IPR018060
- InterPro:   IPR014710 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 31612; Mature: 31612

Theoretical pI: Translated: 8.57; Mature: 8.57

Prosite motif: PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDSKINQKNSPIAYSCYYTQNREGEQFASQHVLSFQISGVLTLNNGSKEYVFNPGDFRF
CCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHEEEEEEEEEEEECCCCCEEEECCCCEEE
IRRNQLIKFIKQPDPNTAFQSISIYLNQEALRDYSIQYNQKTSLIKSPETEMVLQLKEVP
EHHHHHHHHHCCCCCCHHHHHEEEEECHHHHHCCCEEECCCHHHHCCCCHHHHHHHHHHH
LLKSFMNSLIPYINEDQLITEELQALKVNEAITILLQCNPELKDILFDFNEPGKIDLEAF
HHHHHHHHHCCCCCCCHHHHHHHHHHEECCEEEEEEECCCCHHHHHCCCCCCCCCCHHHH
MKKNFHFNVQLDRFAYLTGRSLATFKRDFQRIFDISPSRWLIQKRLQEAYYQIKEKGKTP
HHCCCEEEEEEHHEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCH
SEVYLEVGFEDLSHFSFAFKKQFGMPPSKV
HHEEEEECHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNDSKINQKNSPIAYSCYYTQNREGEQFASQHVLSFQISGVLTLNNGSKEYVFNPGDFRF
CCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHEEEEEEEEEEEECCCCCEEEECCCCEEE
IRRNQLIKFIKQPDPNTAFQSISIYLNQEALRDYSIQYNQKTSLIKSPETEMVLQLKEVP
EHHHHHHHHHCCCCCCHHHHHEEEEECHHHHHCCCEEECCCHHHHCCCCHHHHHHHHHHH
LLKSFMNSLIPYINEDQLITEELQALKVNEAITILLQCNPELKDILFDFNEPGKIDLEAF
HHHHHHHHHCCCCCCCHHHHHHHHHHEECCEEEEEEECCCCHHHHHCCCCCCCCCCHHHH
MKKNFHFNVQLDRFAYLTGRSLATFKRDFQRIFDISPSRWLIQKRLQEAYYQIKEKGKTP
HHCCCEEEEEEHHEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCH
SEVYLEVGFEDLSHFSFAFKKQFGMPPSKV
HHEEEEECHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1655713; 10984043 [H]