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The map label for this gene is silP [H]

Identifier: 146300819

GI number: 146300819

Start: 3642379

End: 3644916

Strand: Direct

Name: silP [H]

Synonym: Fjoh_3074

Alternate gene names: 146300819

Gene position: 3642379-3644916 (Clockwise)

Preceding gene: 146300818

Following gene: 146300820

Centisome position: 59.74

GC content: 39.13

Gene sequence:

>2538_bases
ATGACACACACCTATACAATATCGGGAATGACTTGCGATGGATGTCGTACAAAAGTAGAAAAAACGTTAAATGCTGTAGA
GGGAATAAAAGCAAAGGTCTCCTTAGATCCTCCATTGGCAACTATTACAATGGAAAATCATATTGCGACCGAAGAGCTCC
AAGAAGCATTGACTGCGGTTGGAAAGTACACCATTGAAATGACTCAAACCACGCATTCGCACGAAAAAAAAACGGAGAAA
TCATGCTGTAGCACTGCTGAGAATCATGGACACAAACATGATCATAAAACGACAGCCGTACCTCACAATGATGCGGGTGG
GAAATATTATTGCCCGATGCATTGTGAAGGTGATAAAATGTATGATAAAGCAGGAGATTGTCCTGTATGCGGAATGCATT
TGGTACAAGAACCTGCTGCTGCCCGGGTTCAGCAGTATACCTGTTCAATGCATCCGGAAGTTATAACCGATTCACCAGGT
TCATGTCCTATTTGCGGAATGGATCTGGTGCCACTGGAGCCAAGTGAAAACGAAGACCAAAGAATTTACAAGGATTTGGT
TAAGAAAATGAAAATAGCGGTAGTATTTACTGTTCCCATTTTCGCTATAGCTATGATAGAAATGGCTCACAAGAATCCTC
TACTACAATTAATGGATGCCTCTAAATGGAACTGGGTACAACTTATCTTATCACTTCCTGTTGTCTTTTATGCGTGTTGG
ATATTTTTTGTACGGGCTTGGAAGTCAATAATTACATGGAACTTAAATATGTTTACCCTTATCGGAATTGGTACAGGAGT
GGCATTTTTATTTAGTTTGGCAGGAATGTTTTTCCCAGACGTTTTTCCTAGTGAATTTAAGACCGAACACGGAACAGTGC
TGCTATACTTTGAGGCCACAACGGTTATTCTAACTTTGGTTTTGTTAGGACAATTACTCGAGGCAAGAGCACATAGTCAA
ACCAGTGGTGCTATAAAAGAATTATTAAAACTGGCTCCTACCCAAGCTACTTTGGTAATTGATGGCGGTGATAAAATAAT
CTCAATCCATGATATCAAAAAAGGTAATTTATTACGGGTAAAACCCGGAGACAAAATTCCTGTAGACGGGAAGATTACTG
ATGGTGAAAGCACAGTAGACGAATCGATGATTACCGGCGAACCAATTCCTGTAGATAAAAAAATAGGTGATATGGTGTCT
TCAGGGACTATAAACGGAAACAAATCCTTTATTATGGTTGCCGAAAAAGTTGGTTCGGAAACCTTGCTTTCGCAAATTAT
ACAAATGGTTAATAATGCAAGTCGTTCCAGAGCACCAATTCAGAAACTAGCCGATAGCATCGCTAAATATTTTGTGCCCA
TTGTTGTCGTTATTTCCATTCTTACCTTTTTCATTTGGGCAAAATTTGGTCCGGAACCAGCAATGGTTTATGGATTTATA
AATGCTATTGCAGTATTAATAATTGCTTGCCCTTGTGCATTAGGTTTAGCAACGCCCATGTCTGTAATGGTAGGAGTTGG
AAAAGGCGCTCAATCGGGAATTCTGATAAAAAATGCCGAAGCTTTGGAAAAAATGGACAAAGTAAATGTTCTCATTACGG
ATAAAACAGGAACAATTACGGAGGGCAAACCTTCGGTAGAAAAAATCGTAGCGCTGCAATATTCAGAAGATGAACTGCTG
CAATACATAGCGTCTTTAAATCAGTACAGTGAGCATCCTCTTGCGGAGGCTGTAGTGAAATTTGCAAAAGCTAAAAATGT
TTCTTTGACCAAAGTAGATGATTTTGAAAACATCGCCGGAAAAGGAGTTATCGGAACTGCTATTGATAAAAAGATGGCAT
TAGGGAATAAAAAATTAATGGAGCAAGCAGGGGCAGCTATTTCTGCCACAATTGAAGAAAAAATTATTGCAGAACAAAAA
TTAGGAAAAACAGTTTCTTATATCGCTGTAGATAAAAATGTAGTGGGATTTGTAACGATAACCGATGCTATAAAAGAAAC
AAGTGCTGCAGCTATAAAAGAATTAATGCGCCAAGGGGTTGAAGTAATCATGCTTACGGGAGATAATGTAAATACAGCCA
AAGCGGTTGCAGACGAATTGCATTTAACCTCTTTTCAGGCAGGTTGTTTACCCGAGGATAAATTAAAAGTAATCGAGAAA
CTTCAAGCCGAAGGAAAAATTGTAGCTATGGCGGGAGATGGAATAAATGATGCGCCAGCTTTGGCTCAATCGGACATTGG
AATTGCGATGGGAACAGGAACAGATGTTGCGATCGAAAGCGCCAAGATTACTTTGGTAAAAGGAGATCTGCAAGGAATTG
TAAAAGCAAAAAATCTGAGCCACGCTGTAATGAGCAACATCAAGCAAAACCTATTCTTTGCTTTTGTATATAATGTCTTA
GGCGTACCAGTTGCTGCGGGTGTTTTATATCCATTTTTCGGAATATTACTTTCTCCTATGATTGCTGCCTTGGCAATGAG
TTTTAGTTCGGTATCTGTTATTGTGAATGCATTGCGATTGAGAAGTTTAAAACTCTAA

Upstream 100 bases:

>100_bases
AAATAATTAAATAATTAGAATATGCAGATTGGCTTAAAAAAAATCACTAACTTTCTATATATTAAAGAAATAACGCATCG
GAACTGTAAAAAATAACCTT

Downstream 100 bases:

>100_bases
AGAATAAATAATTTTACTATACAAACAAATGACCAATCTAGGACAAATTATTCTGCAGTATAAAAACGATAACGAAAGTG
TCTATAATACCTGGTTTATA

Product: heavy metal translocating P-type ATPase

Products: ADP; Orthophosphate. [C]

Alternate protein names: NA

Number of amino acids: Translated: 845; Mature: 844

Protein sequence:

>845_residues
MTHTYTISGMTCDGCRTKVEKTLNAVEGIKAKVSLDPPLATITMENHIATEELQEALTAVGKYTIEMTQTTHSHEKKTEK
SCCSTAENHGHKHDHKTTAVPHNDAGGKYYCPMHCEGDKMYDKAGDCPVCGMHLVQEPAAARVQQYTCSMHPEVITDSPG
SCPICGMDLVPLEPSENEDQRIYKDLVKKMKIAVVFTVPIFAIAMIEMAHKNPLLQLMDASKWNWVQLILSLPVVFYACW
IFFVRAWKSIITWNLNMFTLIGIGTGVAFLFSLAGMFFPDVFPSEFKTEHGTVLLYFEATTVILTLVLLGQLLEARAHSQ
TSGAIKELLKLAPTQATLVIDGGDKIISIHDIKKGNLLRVKPGDKIPVDGKITDGESTVDESMITGEPIPVDKKIGDMVS
SGTINGNKSFIMVAEKVGSETLLSQIIQMVNNASRSRAPIQKLADSIAKYFVPIVVVISILTFFIWAKFGPEPAMVYGFI
NAIAVLIIACPCALGLATPMSVMVGVGKGAQSGILIKNAEALEKMDKVNVLITDKTGTITEGKPSVEKIVALQYSEDELL
QYIASLNQYSEHPLAEAVVKFAKAKNVSLTKVDDFENIAGKGVIGTAIDKKMALGNKKLMEQAGAAISATIEEKIIAEQK
LGKTVSYIAVDKNVVGFVTITDAIKETSAAAIKELMRQGVEVIMLTGDNVNTAKAVADELHLTSFQAGCLPEDKLKVIEK
LQAEGKIVAMAGDGINDAPALAQSDIGIAMGTGTDVAIESAKITLVKGDLQGIVKAKNLSHAVMSNIKQNLFFAFVYNVL
GVPVAAGVLYPFFGILLSPMIAALAMSFSSVSVIVNALRLRSLKL

Sequences:

>Translated_845_residues
MTHTYTISGMTCDGCRTKVEKTLNAVEGIKAKVSLDPPLATITMENHIATEELQEALTAVGKYTIEMTQTTHSHEKKTEK
SCCSTAENHGHKHDHKTTAVPHNDAGGKYYCPMHCEGDKMYDKAGDCPVCGMHLVQEPAAARVQQYTCSMHPEVITDSPG
SCPICGMDLVPLEPSENEDQRIYKDLVKKMKIAVVFTVPIFAIAMIEMAHKNPLLQLMDASKWNWVQLILSLPVVFYACW
IFFVRAWKSIITWNLNMFTLIGIGTGVAFLFSLAGMFFPDVFPSEFKTEHGTVLLYFEATTVILTLVLLGQLLEARAHSQ
TSGAIKELLKLAPTQATLVIDGGDKIISIHDIKKGNLLRVKPGDKIPVDGKITDGESTVDESMITGEPIPVDKKIGDMVS
SGTINGNKSFIMVAEKVGSETLLSQIIQMVNNASRSRAPIQKLADSIAKYFVPIVVVISILTFFIWAKFGPEPAMVYGFI
NAIAVLIIACPCALGLATPMSVMVGVGKGAQSGILIKNAEALEKMDKVNVLITDKTGTITEGKPSVEKIVALQYSEDELL
QYIASLNQYSEHPLAEAVVKFAKAKNVSLTKVDDFENIAGKGVIGTAIDKKMALGNKKLMEQAGAAISATIEEKIIAEQK
LGKTVSYIAVDKNVVGFVTITDAIKETSAAAIKELMRQGVEVIMLTGDNVNTAKAVADELHLTSFQAGCLPEDKLKVIEK
LQAEGKIVAMAGDGINDAPALAQSDIGIAMGTGTDVAIESAKITLVKGDLQGIVKAKNLSHAVMSNIKQNLFFAFVYNVL
GVPVAAGVLYPFFGILLSPMIAALAMSFSSVSVIVNALRLRSLKL
>Mature_844_residues
THTYTISGMTCDGCRTKVEKTLNAVEGIKAKVSLDPPLATITMENHIATEELQEALTAVGKYTIEMTQTTHSHEKKTEKS
CCSTAENHGHKHDHKTTAVPHNDAGGKYYCPMHCEGDKMYDKAGDCPVCGMHLVQEPAAARVQQYTCSMHPEVITDSPGS
CPICGMDLVPLEPSENEDQRIYKDLVKKMKIAVVFTVPIFAIAMIEMAHKNPLLQLMDASKWNWVQLILSLPVVFYACWI
FFVRAWKSIITWNLNMFTLIGIGTGVAFLFSLAGMFFPDVFPSEFKTEHGTVLLYFEATTVILTLVLLGQLLEARAHSQT
SGAIKELLKLAPTQATLVIDGGDKIISIHDIKKGNLLRVKPGDKIPVDGKITDGESTVDESMITGEPIPVDKKIGDMVSS
GTINGNKSFIMVAEKVGSETLLSQIIQMVNNASRSRAPIQKLADSIAKYFVPIVVVISILTFFIWAKFGPEPAMVYGFIN
AIAVLIIACPCALGLATPMSVMVGVGKGAQSGILIKNAEALEKMDKVNVLITDKTGTITEGKPSVEKIVALQYSEDELLQ
YIASLNQYSEHPLAEAVVKFAKAKNVSLTKVDDFENIAGKGVIGTAIDKKMALGNKKLMEQAGAAISATIEEKIIAEQKL
GKTVSYIAVDKNVVGFVTITDAIKETSAAAIKELMRQGVEVIMLTGDNVNTAKAVADELHLTSFQAGCLPEDKLKVIEKL
QAEGKIVAMAGDGINDAPALAQSDIGIAMGTGTDVAIESAKITLVKGDLQGIVKAKNLSHAVMSNIKQNLFFAFVYNVLG
VPVAAGVLYPFFGILLSPMIAALAMSFSSVSVIVNALRLRSLKL

Specific function: Component of the sil cation-efflux system that confers resistance to silver [H]

COG id: COG2217

COG function: function code P; Cation transport ATPase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily [H]

Homologues:

Organism=Homo sapiens, GI115529486, Length=683, Percent_Identity=35.4319180087848, Blast_Score=423, Evalue=1e-118,
Organism=Homo sapiens, GI55743071, Length=711, Percent_Identity=35.1617440225035, Blast_Score=416, Evalue=1e-116,
Organism=Homo sapiens, GI55743073, Length=549, Percent_Identity=35.8834244080146, Blast_Score=334, Evalue=2e-91,
Organism=Homo sapiens, GI209413709, Length=195, Percent_Identity=32.8205128205128, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI24638454, Length=195, Percent_Identity=32.8205128205128, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI4502285, Length=195, Percent_Identity=32.8205128205128, Blast_Score=96, Evalue=2e-19,
Organism=Homo sapiens, GI28373109, Length=188, Percent_Identity=33.5106382978723, Blast_Score=94, Evalue=6e-19,
Organism=Homo sapiens, GI28373115, Length=188, Percent_Identity=33.5106382978723, Blast_Score=94, Evalue=6e-19,
Organism=Homo sapiens, GI28373111, Length=188, Percent_Identity=33.5106382978723, Blast_Score=94, Evalue=6e-19,
Organism=Homo sapiens, GI28373107, Length=188, Percent_Identity=33.5106382978723, Blast_Score=94, Evalue=6e-19,
Organism=Homo sapiens, GI28373105, Length=188, Percent_Identity=33.5106382978723, Blast_Score=94, Evalue=7e-19,
Organism=Homo sapiens, GI28373113, Length=188, Percent_Identity=33.5106382978723, Blast_Score=94, Evalue=8e-19,
Organism=Homo sapiens, GI28373103, Length=188, Percent_Identity=33.5106382978723, Blast_Score=94, Evalue=8e-19,
Organism=Homo sapiens, GI48762689, Length=167, Percent_Identity=35.9281437125749, Blast_Score=91, Evalue=6e-18,
Organism=Homo sapiens, GI48762691, Length=167, Percent_Identity=35.9281437125749, Blast_Score=91, Evalue=7e-18,
Organism=Homo sapiens, GI27886529, Length=221, Percent_Identity=30.316742081448, Blast_Score=91, Evalue=7e-18,
Organism=Homo sapiens, GI48762685, Length=167, Percent_Identity=35.9281437125749, Blast_Score=90, Evalue=7e-18,
Organism=Homo sapiens, GI48762687, Length=167, Percent_Identity=35.9281437125749, Blast_Score=90, Evalue=7e-18,
Organism=Homo sapiens, GI10835220, Length=180, Percent_Identity=32.7777777777778, Blast_Score=90, Evalue=8e-18,
Organism=Homo sapiens, GI118498343, Length=167, Percent_Identity=37.7245508982036, Blast_Score=89, Evalue=2e-17,
Organism=Homo sapiens, GI310128958, Length=169, Percent_Identity=32.5443786982249, Blast_Score=86, Evalue=2e-16,
Organism=Homo sapiens, GI297374799, Length=240, Percent_Identity=25.4166666666667, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI83700225, Length=240, Percent_Identity=25.4166666666667, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI153946397, Length=132, Percent_Identity=31.0606060606061, Blast_Score=77, Evalue=9e-14,
Organism=Homo sapiens, GI4502271, Length=199, Percent_Identity=27.6381909547739, Blast_Score=76, Evalue=2e-13,
Organism=Homo sapiens, GI21361181, Length=199, Percent_Identity=27.1356783919598, Blast_Score=75, Evalue=3e-13,
Organism=Homo sapiens, GI237681111, Length=199, Percent_Identity=27.1356783919598, Blast_Score=75, Evalue=3e-13,
Organism=Homo sapiens, GI237681109, Length=199, Percent_Identity=27.1356783919598, Blast_Score=75, Evalue=3e-13,
Organism=Homo sapiens, GI22748667, Length=225, Percent_Identity=25.3333333333333, Blast_Score=74, Evalue=6e-13,
Organism=Homo sapiens, GI51944966, Length=146, Percent_Identity=28.7671232876712, Blast_Score=74, Evalue=8e-13,
Organism=Escherichia coli, GI1786691, Length=684, Percent_Identity=43.1286549707602, Blast_Score=519, Evalue=1e-148,
Organism=Escherichia coli, GI1789879, Length=561, Percent_Identity=33.5115864527629, Blast_Score=271, Evalue=1e-73,
Organism=Escherichia coli, GI1786914, Length=427, Percent_Identity=29.7423887587822, Blast_Score=166, Evalue=4e-42,
Organism=Escherichia coli, GI2367363, Length=627, Percent_Identity=23.6044657097289, Blast_Score=107, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17556548, Length=744, Percent_Identity=35.3494623655914, Blast_Score=377, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI193210130, Length=238, Percent_Identity=28.1512605042017, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71988506, Length=238, Percent_Identity=28.1512605042017, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17554158, Length=238, Percent_Identity=28.1512605042017, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71997275, Length=187, Percent_Identity=31.5508021390374, Blast_Score=88, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71997262, Length=187, Percent_Identity=31.5508021390374, Blast_Score=88, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71997269, Length=169, Percent_Identity=32.5443786982249, Blast_Score=84, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17531459, Length=144, Percent_Identity=37.5, Blast_Score=83, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17557486, Length=217, Percent_Identity=29.0322580645161, Blast_Score=76, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17559224, Length=130, Percent_Identity=30, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17557770, Length=213, Percent_Identity=25.8215962441315, Blast_Score=73, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI32566766, Length=213, Percent_Identity=25.8215962441315, Blast_Score=73, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6320475, Length=643, Percent_Identity=37.4805598755832, Blast_Score=372, Evalue=1e-103,
Organism=Saccharomyces cerevisiae, GI6319772, Length=680, Percent_Identity=28.5294117647059, Blast_Score=274, Evalue=4e-74,
Organism=Saccharomyces cerevisiae, GI6321430, Length=582, Percent_Identity=25.085910652921, Blast_Score=133, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6325221, Length=582, Percent_Identity=24.5704467353952, Blast_Score=127, Evalue=7e-30,
Organism=Saccharomyces cerevisiae, GI6321271, Length=187, Percent_Identity=33.1550802139037, Blast_Score=94, Evalue=9e-20,
Organism=Saccharomyces cerevisiae, GI6321432, Length=180, Percent_Identity=32.7777777777778, Blast_Score=89, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6320243, Length=218, Percent_Identity=29.8165137614679, Blast_Score=87, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6320244, Length=218, Percent_Identity=29.8165137614679, Blast_Score=87, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6320245, Length=218, Percent_Identity=29.3577981651376, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI221329854, Length=468, Percent_Identity=36.5384615384615, Blast_Score=251, Evalue=2e-66,
Organism=Drosophila melanogaster, GI24762455, Length=195, Percent_Identity=31.2820512820513, Blast_Score=88, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24762453, Length=195, Percent_Identity=31.2820512820513, Blast_Score=88, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24762447, Length=195, Percent_Identity=31.2820512820513, Blast_Score=88, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24762457, Length=195, Percent_Identity=31.2820512820513, Blast_Score=88, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24762449, Length=195, Percent_Identity=31.2820512820513, Blast_Score=88, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24762445, Length=195, Percent_Identity=31.2820512820513, Blast_Score=88, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24762451, Length=195, Percent_Identity=31.2820512820513, Blast_Score=88, Evalue=3e-17,
Organism=Drosophila melanogaster, GI17136664, Length=195, Percent_Identity=31.2820512820513, Blast_Score=88, Evalue=3e-17,
Organism=Drosophila melanogaster, GI161085803, Length=166, Percent_Identity=34.3373493975904, Blast_Score=87, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24668704, Length=166, Percent_Identity=34.3373493975904, Blast_Score=86, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24668708, Length=166, Percent_Identity=34.3373493975904, Blast_Score=86, Evalue=8e-17,
Organism=Drosophila melanogaster, GI281366617, Length=166, Percent_Identity=34.3373493975904, Blast_Score=86, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24668696, Length=166, Percent_Identity=34.3373493975904, Blast_Score=86, Evalue=9e-17,
Organism=Drosophila melanogaster, GI281366676, Length=218, Percent_Identity=25.6880733944954, Blast_Score=76, Evalue=1e-13,
Organism=Drosophila melanogaster, GI281362164, Length=199, Percent_Identity=26.6331658291457, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI45553441, Length=199, Percent_Identity=26.6331658291457, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24648580, Length=199, Percent_Identity=26.6331658291457, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24648578, Length=199, Percent_Identity=26.6331658291457, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24648576, Length=199, Percent_Identity=26.6331658291457, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24648582, Length=199, Percent_Identity=26.6331658291457, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI45553435, Length=199, Percent_Identity=26.6331658291457, Blast_Score=72, Evalue=2e-12,
Organism=Drosophila melanogaster, GI45553437, Length=199, Percent_Identity=26.6331658291457, Blast_Score=72, Evalue=2e-12,
Organism=Drosophila melanogaster, GI45553439, Length=199, Percent_Identity=26.6331658291457, Blast_Score=72, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008250
- InterPro:   IPR006403
- InterPro:   IPR006416
- InterPro:   IPR001757
- InterPro:   IPR018303
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR007029 [H]

Pfam domain/function: PF00122 E1-E2_ATPase; PF00702 Hydrolase; PF04945 YHS [H]

EC number: 3.6.3.4 [C]

Molecular weight: Translated: 91157; Mature: 91025

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS00154 ATPASE_E1_E2 ; PS01047 HMA_1 ; PS50846 HMA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHTYTISGMTCDGCRTKVEKTLNAVEGIKAKVSLDPPLATITMENHIATEELQEALTAV
CCEEEEECCEECCHHHHHHHHHHHHHHCCEEEEECCCCEEEEEECCCCCHHHHHHHHHHH
GKYTIEMTQTTHSHEKKTEKSCCSTAENHGHKHDHKTTAVPHNDAGGKYYCPMHCEGDKM
HHEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECEECCCCHH
YDKAGDCPVCGMHLVQEPAAARVQQYTCSMHPEVITDSPGSCPICGMDLVPLEPSENEDQ
HHCCCCCCHHHHHHHHCHHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCEECCCCCCHHH
RIYKDLVKKMKIAVVFTVPIFAIAMIEMAHKNPLLQLMDASKWNWVQLILSLPVVFYACW
HHHHHHHHHHHHHEEEHHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHHHHH
IFFVRAWKSIITWNLNMFTLIGIGTGVAFLFSLAGMFFPDVFPSEFKTEHGTVLLYFEAT
HHHHHHHHHHHEECCCEEEEEEHHHHHHHHHHHHHHHCCCCCCHHHCCCCCEEEEEECHH
TVILTLVLLGQLLEARAHSQTSGAIKELLKLAPTQATLVIDGGDKIISIHDIKKGNLLRV
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEEECCCEEEEEEECCCCCEEEE
KPGDKIPVDGKITDGESTVDESMITGEPIPVDKKIGDMVSSGTINGNKSFIMVAEKVGSE
CCCCCCCCCCEECCCCHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCEEEEEHHHCHH
TLLSQIIQMVNNASRSRAPIQKLADSIAKYFVPIVVVISILTFFIWAKFGPEPAMVYGFI
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
NAIAVLIIACPCALGLATPMSVMVGVGKGAQSGILIKNAEALEKMDKVNVLITDKTGTIT
HHHHHHHHHHHHHHHHHCHHHHHHCCCCCCCCCEEEECHHHHHHHHHCEEEEECCCCCCC
EGKPSVEKIVALQYSEDELLQYIASLNQYSEHPLAEAVVKFAKAKNVSLTKVDDFENIAG
CCCCCHHHHEEEECCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEECCCHHHHCC
KGVIGTAIDKKMALGNKKLMEQAGAAISATIEEKIIAEQKLGKTVSYIAVDKNVVGFVTI
CCCEEHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHCCEEEEEEECCCEEEEEEE
TDAIKETSAAAIKELMRQGVEVIMLTGDNVNTAKAVADELHLTSFQAGCLPEDKLKVIEK
HHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
LQAEGKIVAMAGDGINDAPALAQSDIGIAMGTGTDVAIESAKITLVKGDLQGIVKAKNLS
HHCCCCEEEEECCCCCCCCCHHHCCCCEEECCCCCEEEECEEEEEEECCHHHHHHHHCHH
HAVMSNIKQNLFFAFVYNVLGVPVAAGVLYPFFGILLSPMIAALAMSFSSVSVIVNALRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSLKL
HHCCC
>Mature Secondary Structure 
THTYTISGMTCDGCRTKVEKTLNAVEGIKAKVSLDPPLATITMENHIATEELQEALTAV
CEEEEECCEECCHHHHHHHHHHHHHHCCEEEEECCCCEEEEEECCCCCHHHHHHHHHHH
GKYTIEMTQTTHSHEKKTEKSCCSTAENHGHKHDHKTTAVPHNDAGGKYYCPMHCEGDKM
HHEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECEECCCCHH
YDKAGDCPVCGMHLVQEPAAARVQQYTCSMHPEVITDSPGSCPICGMDLVPLEPSENEDQ
HHCCCCCCHHHHHHHHCHHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCEECCCCCCHHH
RIYKDLVKKMKIAVVFTVPIFAIAMIEMAHKNPLLQLMDASKWNWVQLILSLPVVFYACW
HHHHHHHHHHHHHEEEHHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHHHHH
IFFVRAWKSIITWNLNMFTLIGIGTGVAFLFSLAGMFFPDVFPSEFKTEHGTVLLYFEAT
HHHHHHHHHHHEECCCEEEEEEHHHHHHHHHHHHHHHCCCCCCHHHCCCCCEEEEEECHH
TVILTLVLLGQLLEARAHSQTSGAIKELLKLAPTQATLVIDGGDKIISIHDIKKGNLLRV
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEEECCCEEEEEEECCCCCEEEE
KPGDKIPVDGKITDGESTVDESMITGEPIPVDKKIGDMVSSGTINGNKSFIMVAEKVGSE
CCCCCCCCCCEECCCCHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCEEEEEHHHCHH
TLLSQIIQMVNNASRSRAPIQKLADSIAKYFVPIVVVISILTFFIWAKFGPEPAMVYGFI
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
NAIAVLIIACPCALGLATPMSVMVGVGKGAQSGILIKNAEALEKMDKVNVLITDKTGTIT
HHHHHHHHHHHHHHHHHCHHHHHHCCCCCCCCCEEEECHHHHHHHHHCEEEEECCCCCCC
EGKPSVEKIVALQYSEDELLQYIASLNQYSEHPLAEAVVKFAKAKNVSLTKVDDFENIAG
CCCCCHHHHEEEECCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEECCCHHHHCC
KGVIGTAIDKKMALGNKKLMEQAGAAISATIEEKIIAEQKLGKTVSYIAVDKNVVGFVTI
CCCEEHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHCCEEEEEEECCCEEEEEEE
TDAIKETSAAAIKELMRQGVEVIMLTGDNVNTAKAVADELHLTSFQAGCLPEDKLKVIEK
HHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
LQAEGKIVAMAGDGINDAPALAQSDIGIAMGTGTDVAIESAKITLVKGDLQGIVKAKNLS
HHCCCCEEEEECCCCCCCCCHHHCCCCEEECCCCCEEEECEEEEEEECCHHHHHHHHCHH
HAVMSNIKQNLFFAFVYNVLGVPVAAGVLYPFFGILLSPMIAALAMSFSSVSVIVNALRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSLKL
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Cu [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O [C]

Specific reaction: ATP + H2O = ADP + Orthophosphate. [C]

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9930866 [H]