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The map label for this gene is arsB [H]

Identifier: 146300740

GI number: 146300740

Start: 3538814

End: 3539845

Strand: Direct

Name: arsB [H]

Synonym: Fjoh_2991

Alternate gene names: 146300740

Gene position: 3538814-3539845 (Clockwise)

Preceding gene: 146300739

Following gene: 146300741

Centisome position: 58.04

GC content: 37.21

Gene sequence:

>1032_bases
ATGCAAGTAAAATTAAAATTTCTTGACCGTTACCTGACCTTATGGATATTCCTTGCCATGGCATTAGGTGTAGCATTGGG
TTATTTCTTTCCAGAGATTTCAAAAATTACAAATGCTCTATCCGTTGGCACTACAAATATTCCATTGGCAACAGGTTTAA
TACTGATGATGTACCCGCCATTGGCAAAAGTGGATTATTCATTGTTGCCACAAGTCTTTAAGGACAAAAAAGTAATTGGC
ATATCGTTAATGCTGAATTGGGTTATTGGTACTGGGTTGATGTTCGGCTTAGCCGTTCTGTTTTTACACAACGAACCTGA
TTATATGACAGGCTTGATATTGATAGGCTTGGCAAGATGTATTGCAATGGTAATCGTATGGAGCGACTTGGCTAAAGCAA
ATAGAGAATATACAGCGATGTTAGTAGCCTTAAACAGTATCTTTCAGATACTTTCTTACAGCTTCTTAGTTTGGCTGTTC
ATCAACGTATTGCCAAGCAAATTAGGTTTAGCCAACTACAACGTAAGCGTATCGATGAAAGATGTAACAGAAAGTGTAAT
CATATACTTGGGTGTTCCATTTTTAGCAGGTTTTATAAGCCGTTACGCATTGGTAAAATCAAAAGGCATAGAGTGGTATA
ACAGAATATTCGTACCCAAAATATCACCCATTACATTATATGCTTTACTGTTTACAATCGCATTAATGTTCAGTCTAAAA
GGCGATAAAATAGTAGAGTTGCCATTGGATGTGGTAAAAGTAGCCATACCGTTAATCATCTATTTTGTACTGATGTTTTT
CGTGAGCTTCTTTATCAATAAAACCTTAAAAATTCCCTACGATAAAAACGCATCCATCGCCTTTACTGCCACTGGAAACA
ATTTTGAATTGGCAATAGCTGTAGCCATAGCGGTTTTCGGTATCCATTCGCCGCAGGCATTTGTGGGCGTTATTGGGCCA
TTGGTTGAAGTGCCCGTATTGATACTTTTAGTCAAGGCAAGTTTATGGTTGAACAAGAAATATTATAGTTAA

Upstream 100 bases:

>100_bases
TTCAGATCATACACCAGAACAATCAAAGGTGTATGCTGAAAGAAGTTTGCAGATAGCAGCGGAAATGTTTTATGTCTTCT
CAAAAATCAGCCGATAAGTC

Downstream 100 bases:

>100_bases
TTTTATAAACATCAAATATAGAAGTTATAACGGATTGAAAAAGACCATATCCATAAAAACCAAAATTGAAGCGGCAGCAT
TATTAAAAGTTGCACCGTTC

Product: arsenical-resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MQVKLKFLDRYLTLWIFLAMALGVALGYFFPEISKITNALSVGTTNIPLATGLILMMYPPLAKVDYSLLPQVFKDKKVIG
ISLMLNWVIGTGLMFGLAVLFLHNEPDYMTGLILIGLARCIAMVIVWSDLAKANREYTAMLVALNSIFQILSYSFLVWLF
INVLPSKLGLANYNVSVSMKDVTESVIIYLGVPFLAGFISRYALVKSKGIEWYNRIFVPKISPITLYALLFTIALMFSLK
GDKIVELPLDVVKVAIPLIIYFVLMFFVSFFINKTLKIPYDKNASIAFTATGNNFELAIAVAIAVFGIHSPQAFVGVIGP
LVEVPVLILLVKASLWLNKKYYS

Sequences:

>Translated_343_residues
MQVKLKFLDRYLTLWIFLAMALGVALGYFFPEISKITNALSVGTTNIPLATGLILMMYPPLAKVDYSLLPQVFKDKKVIG
ISLMLNWVIGTGLMFGLAVLFLHNEPDYMTGLILIGLARCIAMVIVWSDLAKANREYTAMLVALNSIFQILSYSFLVWLF
INVLPSKLGLANYNVSVSMKDVTESVIIYLGVPFLAGFISRYALVKSKGIEWYNRIFVPKISPITLYALLFTIALMFSLK
GDKIVELPLDVVKVAIPLIIYFVLMFFVSFFINKTLKIPYDKNASIAFTATGNNFELAIAVAIAVFGIHSPQAFVGVIGP
LVEVPVLILLVKASLWLNKKYYS
>Mature_343_residues
MQVKLKFLDRYLTLWIFLAMALGVALGYFFPEISKITNALSVGTTNIPLATGLILMMYPPLAKVDYSLLPQVFKDKKVIG
ISLMLNWVIGTGLMFGLAVLFLHNEPDYMTGLILIGLARCIAMVIVWSDLAKANREYTAMLVALNSIFQILSYSFLVWLF
INVLPSKLGLANYNVSVSMKDVTESVIIYLGVPFLAGFISRYALVKSKGIEWYNRIFVPKISPITLYALLFTIALMFSLK
GDKIVELPLDVVKVAIPLIIYFVLMFFVSFFINKTLKIPYDKNASIAFTATGNNFELAIAVAIAVFGIHSPQAFVGVIGP
LVEVPVLILLVKASLWLNKKYYS

Specific function: Seems to confer resistance to arsenite by allowing cells to extrude this compound. Could be part of an arsenite extrusion pump [H]

COG id: COG0798

COG function: function code P; Arsenite efflux pump ACR3 and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ACR3 family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6325459, Length=316, Percent_Identity=30.379746835443, Blast_Score=141, Evalue=1e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004706
- InterPro:   IPR002657 [H]

Pfam domain/function: PF01758 SBF [H]

EC number: NA

Molecular weight: Translated: 38212; Mature: 38212

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVKLKFLDRYLTLWIFLAMALGVALGYFFPEISKITNALSVGTTNIPLATGLILMMYPP
CEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCC
LAKVDYSLLPQVFKDKKVIGISLMLNWVIGTGLMFGLAVLFLHNEPDYMTGLILIGLARC
HHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
IAMVIVWSDLAKANREYTAMLVALNSIFQILSYSFLVWLFINVLPSKLGLANYNVSVSMK
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHH
DVTESVIIYLGVPFLAGFISRYALVKSKGIEWYNRIFVPKISPITLYALLFTIALMFSLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHEEECCCCCHHHHHHHHHHHHHHHHCC
GDKIVELPLDVVKVAIPLIIYFVLMFFVSFFINKTLKIPYDKNASIAFTATGNNFELAIA
CCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCEEEEEECCCEEHHHH
VAIAVFGIHSPQAFVGVIGPLVEVPVLILLVKASLWLNKKYYS
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MQVKLKFLDRYLTLWIFLAMALGVALGYFFPEISKITNALSVGTTNIPLATGLILMMYPP
CEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCC
LAKVDYSLLPQVFKDKKVIGISLMLNWVIGTGLMFGLAVLFLHNEPDYMTGLILIGLARC
HHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
IAMVIVWSDLAKANREYTAMLVALNSIFQILSYSFLVWLFINVLPSKLGLANYNVSVSMK
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHH
DVTESVIIYLGVPFLAGFISRYALVKSKGIEWYNRIFVPKISPITLYALLFTIALMFSLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHEEECCCCCHHHHHHHHHHHHHHHHCC
GDKIVELPLDVVKVAIPLIIYFVLMFFVSFFINKTLKIPYDKNASIAFTATGNNFELAIA
CCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCEEEEEECCCEEHHHH
VAIAVFGIHSPQAFVGVIGPLVEVPVLILLVKASLWLNKKYYS
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7704261; 8969508; 9384377; 7489895; 9537360 [H]