Click here to switch to the map view.

The map label for this gene is kdsC [H]

Identifier: 146300702

GI number: 146300702

Start: 3501282

End: 3501809

Strand: Direct

Name: kdsC [H]

Synonym: Fjoh_2953

Alternate gene names: 146300702

Gene position: 3501282-3501809 (Clockwise)

Preceding gene: 146300701

Following gene: 146300703

Centisome position: 57.43

GC content: 37.69

Gene sequence:

>528_bases
ATGGCAAAAAGTTATAAAGAAATGATGAACGACATTACAACATTTATTTTTGATGTTGATGGCGTACTTACAGACAGTTC
GGTTTTTGTAACCACAGAAGGAGAAATTCTTCGTACGATGAATATTCGTGACGGTTATGCCATGAAAGCGGCTGTAGAAA
GCGGTTACAATGTGTGCATTATTTCTGGCGGCAGCAACGAAGGTGTCCGCGTAAGACTTCAAAATTTAGGAATTACTGAT
ATTCATTTAGGAACTCCTGATAAAGTTAAAACATTTAAAGAGTATACAGAAGCGAACAACATCAAACCAGAACAGGTTTT
ATATATGGGAGACGATATTCCGGATTATCATGTAATGAAATTAGTAGGTTTACCAGCTTCTCCTCAGGATGCAGTTCCTG
AAATTAAAAACATCTGCCGTTATATTTCGCACGTAAAAGGCGGAAAAGGCGCTGCAAGAGACGTTATCGAACAGGTGATG
AAAGTACAGGGAAAATGGATGGAATATTTTAACGGAAAACACGATTAA

Upstream 100 bases:

>100_bases
AAACGACATGATTCGGTTACAACCGATGCACATTTGGATTTTATTACCAATGAAAATCAAAAAAATATTTATAAAATACT
AACACAATCTATACAGAATA

Downstream 100 bases:

>100_bases
ATCTAATTGTGAATTGTTAATGATTAATTGTTAATTAAAAAACTTAGAACCTTAGCATCTTAGCCACTCAGAACCTCAAA
AAATGAAATATCTAAAACTA

Product: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase

Products: NA

Alternate protein names: KDO 8-P phosphatase [H]

Number of amino acids: Translated: 175; Mature: 174

Protein sequence:

>175_residues
MAKSYKEMMNDITTFIFDVDGVLTDSSVFVTTEGEILRTMNIRDGYAMKAAVESGYNVCIISGGSNEGVRVRLQNLGITD
IHLGTPDKVKTFKEYTEANNIKPEQVLYMGDDIPDYHVMKLVGLPASPQDAVPEIKNICRYISHVKGGKGAARDVIEQVM
KVQGKWMEYFNGKHD

Sequences:

>Translated_175_residues
MAKSYKEMMNDITTFIFDVDGVLTDSSVFVTTEGEILRTMNIRDGYAMKAAVESGYNVCIISGGSNEGVRVRLQNLGITD
IHLGTPDKVKTFKEYTEANNIKPEQVLYMGDDIPDYHVMKLVGLPASPQDAVPEIKNICRYISHVKGGKGAARDVIEQVM
KVQGKWMEYFNGKHD
>Mature_174_residues
AKSYKEMMNDITTFIFDVDGVLTDSSVFVTTEGEILRTMNIRDGYAMKAAVESGYNVCIISGGSNEGVRVRLQNLGITDI
HLGTPDKVKTFKEYTEANNIKPEQVLYMGDDIPDYHVMKLVGLPASPQDAVPEIKNICRYISHVKGGKGAARDVIEQVMK
VQGKWMEYFNGKHD

Specific function: Catalyzes the hydrolysis of KDO 8-P to KDO and inorganic phosphate [H]

COG id: COG1778

COG function: function code R; Low specificity phosphatase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsC family [H]

Homologues:

Organism=Homo sapiens, GI8923900, Length=155, Percent_Identity=24.5161290322581, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI2367202, Length=158, Percent_Identity=38.6075949367089, Blast_Score=117, Evalue=4e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006549
- InterPro:   IPR010023 [H]

Pfam domain/function: PF08282 Hydrolase_3 [H]

EC number: =3.1.3.45 [H]

Molecular weight: Translated: 19515; Mature: 19383

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKSYKEMMNDITTFIFDVDGVLTDSSVFVTTEGEILRTMNIRDGYAMKAAVESGYNVCI
CCCHHHHHHHHHHHHHHCCCCEEECCEEEEEECCCEEEEEECCCCHHHHHHHHCCCCEEE
ISGGSNEGVRVRLQNLGITDIHLGTPDKVKTFKEYTEANNIKPEQVLYMGDDIPDYHVMK
EECCCCCCEEEEEECCCEEEEECCCCHHHHHHHHHHHHCCCCHHHEEEECCCCCCHHHHH
LVGLPASPQDAVPEIKNICRYISHVKGGKGAARDVIEQVMKVQGKWMEYFNGKHD
EECCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
AKSYKEMMNDITTFIFDVDGVLTDSSVFVTTEGEILRTMNIRDGYAMKAAVESGYNVCI
CCHHHHHHHHHHHHHHCCCCEEECCEEEEEECCCEEEEEECCCCHHHHHHHHCCCCEEE
ISGGSNEGVRVRLQNLGITDIHLGTPDKVKTFKEYTEANNIKPEQVLYMGDDIPDYHVMK
EECCCCCCEEEEEECCCEEEEECCCCHHHHHHHHHHHHCCCCHHHEEEECCCCCCHHHHH
LVGLPASPQDAVPEIKNICRYISHVKGGKGAARDVIEQVMKVQGKWMEYFNGKHD
EECCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]