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The map label for this gene is lpxA [H]

Identifier: 146300651

GI number: 146300651

Start: 3444071

End: 3444856

Strand: Reverse

Name: lpxA [H]

Synonym: Fjoh_2902

Alternate gene names: 146300651

Gene position: 3444856-3444071 (Counterclockwise)

Preceding gene: 146300652

Following gene: 146300650

Centisome position: 56.5

GC content: 35.11

Gene sequence:

>786_bases
ATGAATCAACCATTAGCATATGTTCATCCTGGCGCGAAAATCGCTAAAAACGTTGTAATTGAGCCTTTTACAACAATTCA
CAATAATGTTGTTATTGGTGATGGTACTTGGATTGGTTCAAATGTAACCATTATGGAAGGAGCTCGAATTGGAAAAAATT
GTAACATTTTTCCAGGAGCTGTAATTTCTGCTGTGCCTCAGGATTTAAAATTTGGCGGTGAAGATTCTTTAGCTATTATT
GGTGACAATTGTACAATTAGAGAGTGTGTAACTATTAATAGAGGAACAATTGCTTCAGGACAGACTATTCTTGGAAACAA
TTGCTTAGTTATGGCTTACGCTCACATTGCTCACGATTGCGAAATTGGTAATAATGCAATTATTGTAAACGGTGTAGCAT
TAGCTGGTCACGTAGTTGTAGGTAATCATGCCGTAATTGGCGGTTTGGCTGCAATTCACCAGTTTATTCATATTGGAGAT
CATGCTATGATTTCTGGCGGATCTCTGGTAAGAAAAGATGTTCCTCCTTACACAAAAGCGGCTAAAGAACCATTGTCGTA
TGTTGGTATCAATTCAGTTGGTTTAAGAAGAAGAGGATTTAGTACTGAAAAAATTAGAGAAATTCAGGAAATTTACAGAA
TTTTATATCAAAAGAATTACAATACTACGCAAGCTTTAAGTATTATTGAAGCTGAAATGGAAGCAACTCCTGAGAGAGAT
GAAATTCTTGATTTTATTAGAAATTCATCACGAGGAATTATGAAAGGTTATTCAGGAAACTATTAA

Upstream 100 bases:

>100_bases
TTAATGGCACAAATTGCAAGAAAACAATAATTAATCAAATTTATTGTTTAGGTTTGTTGCCCTAAAATTAGATTATTTTA
ATTTAAAATATAAAACATAG

Downstream 100 bases:

>100_bases
TTTTAGAGTTTAGATTTCTGGTTTTAGATTTCTAAGCAACAGATTAAAACTGAAAAATAAAATATTAAATAAAAAACAAT
GAAGATTGGATTCTTTATTT

Product: UDP-N-acetylglucosamine acyltransferase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine acyltransferase [H]

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MNQPLAYVHPGAKIAKNVVIEPFTTIHNNVVIGDGTWIGSNVTIMEGARIGKNCNIFPGAVISAVPQDLKFGGEDSLAII
GDNCTIRECVTINRGTIASGQTILGNNCLVMAYAHIAHDCEIGNNAIIVNGVALAGHVVVGNHAVIGGLAAIHQFIHIGD
HAMISGGSLVRKDVPPYTKAAKEPLSYVGINSVGLRRRGFSTEKIREIQEIYRILYQKNYNTTQALSIIEAEMEATPERD
EILDFIRNSSRGIMKGYSGNY

Sequences:

>Translated_261_residues
MNQPLAYVHPGAKIAKNVVIEPFTTIHNNVVIGDGTWIGSNVTIMEGARIGKNCNIFPGAVISAVPQDLKFGGEDSLAII
GDNCTIRECVTINRGTIASGQTILGNNCLVMAYAHIAHDCEIGNNAIIVNGVALAGHVVVGNHAVIGGLAAIHQFIHIGD
HAMISGGSLVRKDVPPYTKAAKEPLSYVGINSVGLRRRGFSTEKIREIQEIYRILYQKNYNTTQALSIIEAEMEATPERD
EILDFIRNSSRGIMKGYSGNY
>Mature_261_residues
MNQPLAYVHPGAKIAKNVVIEPFTTIHNNVVIGDGTWIGSNVTIMEGARIGKNCNIFPGAVISAVPQDLKFGGEDSLAII
GDNCTIRECVTINRGTIASGQTILGNNCLVMAYAHIAHDCEIGNNAIIVNGVALAGHVVVGNHAVIGGLAAIHQFIHIGD
HAMISGGSLVRKDVPPYTKAAKEPLSYVGINSVGLRRRGFSTEKIREIQEIYRILYQKNYNTTQALSIIEAEMEATPERD
EILDFIRNSSRGIMKGYSGNY

Specific function: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell [H]

COG id: COG1043

COG function: function code M; Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family. LpxA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786378, Length=254, Percent_Identity=42.1259842519685, Blast_Score=190, Evalue=9e-50,
Organism=Escherichia coli, GI1786376, Length=196, Percent_Identity=31.1224489795918, Blast_Score=80, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001451
- InterPro:   IPR010137
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00132 Hexapep [H]

EC number: =2.3.1.129 [H]

Molecular weight: Translated: 28126; Mature: 28126

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQPLAYVHPGAKIAKNVVIEPFTTIHNNVVIGDGTWIGSNVTIMEGARIGKNCNIFPGA
CCCCCEEECCCHHHHHHEEECCHHHHCCCEEEECCEEECCCEEEEECCCCCCCCCCCCCH
VISAVPQDLKFGGEDSLAIIGDNCTIRECVTINRGTIASGQTILGNNCLVMAYAHIAHDC
HHHHCCHHHCCCCCCCEEEEECCCEEEEEEEECCCCCCCCCEEECCCEEEEEEEHHHHHC
EIGNNAIIVNGVALAGHVVVGNHAVIGGLAAIHQFIHIGDHAMISGGSLVRKDVPPYTKA
CCCCCEEEEEEEEEEEEEEECCCHHHHHHHHHHHHHHCCCCEEECCCCEEECCCCCHHHH
AKEPLSYVGINSVGLRRRGFSTEKIREIQEIYRILYQKNYNTTQALSIIEAEMEATPERD
HHCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHH
EILDFIRNSSRGIMKGYSGNY
HHHHHHHCCCCCEECCCCCCC
>Mature Secondary Structure
MNQPLAYVHPGAKIAKNVVIEPFTTIHNNVVIGDGTWIGSNVTIMEGARIGKNCNIFPGA
CCCCCEEECCCHHHHHHEEECCHHHHCCCEEEECCEEECCCEEEEECCCCCCCCCCCCCH
VISAVPQDLKFGGEDSLAIIGDNCTIRECVTINRGTIASGQTILGNNCLVMAYAHIAHDC
HHHHCCHHHCCCCCCCEEEEECCCEEEEEEEECCCCCCCCCEEECCCEEEEEEEHHHHHC
EIGNNAIIVNGVALAGHVVVGNHAVIGGLAAIHQFIHIGDHAMISGGSLVRKDVPPYTKA
CCCCCEEEEEEEEEEEEEEECCCHHHHHHHHHHHHHHCCCCEEECCCCEEECCCCCHHHH
AKEPLSYVGINSVGLRRRGFSTEKIREIQEIYRILYQKNYNTTQALSIIEAEMEATPERD
HHCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHH
EILDFIRNSSRGIMKGYSGNY
HHHHHHHCCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA