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The map label for this gene is purC [H]

Identifier: 146300478

GI number: 146300478

Start: 3250297

End: 3251250

Strand: Direct

Name: purC [H]

Synonym: Fjoh_2728

Alternate gene names: 146300478

Gene position: 3250297-3251250 (Clockwise)

Preceding gene: 146300477

Following gene: 146300479

Centisome position: 53.31

GC content: 34.59

Gene sequence:

>954_bases
ATGAGTAATACAATCACAACCACAAATTTTAATTTCCCGAATCAGAAATCAGTTTACCGAGGAAAAGTTAGAGAAGTTTA
CAATATTAACGACGAACTTTTAGTAATGGTAGCAACAGACAGACTTTCGGCGTTTGATGTGGTTTTACCAAAAGGAATTC
CGTACAAAGGACAAATTTTGAACCAGATTGCAACAAAATTTATGGAGTTAACTCAGGATATTGTTCCAAACTGGTTAATT
GCAACTCCAGATCCAAACGTTGCTGTTGGGCATTTATGCGAACCTTTTAAAGTAGAAATGGTTATTCGAGGTTATCTTTC
AGGACATGCAGCACGTGAATATGCTGCAGGAAGAAAACAAATTTGCGGTGTAACAATGGCCGAAGGTTTAAAAGAAAACG
ATAAATTTCCAGAACCAATCATTACGCCGACTACAAAAGCAGATAATGGTTCGCATGATGAAGATATATCTCGTGAAGCT
ATTTTGTCTAAAGGAATTATTTCTGAAGAAGATTATTTAGTTTTAGAAAAATATACACGTGCTTTATTTCAAAGAGGAAC
TGAAATTGCTGCTTCCCGCGGGTTAATTTTAGTTGATACTAAATACGAATTTGGAAAAACAAAAGACGGTGTTATTGTTT
TAATTGATGAAATTCATACTCCGGATTCTTCTCGTTATTTTTATGCTGATGGATATGCTGAAAGACAAGAAAAAGGAGAG
GAGCAAAAACAGCTTTCAAAAGAGTTTGTTCGCCGCTGGCTGATCGAAAACGGTTTTCAGGGGCAGGAAGGACAGCAGAT
TCCAGATATGTCAGATGAATATATTGAATCTGTTTCTGAAAGATATATTGAATTGTATGAAAATATCTTAGGAGAAAAAT
TCGTAAAAGCTGATATTGACAATATTGATCAACGTATTGAAAAAAACGTATTACAATACCTTACTTCTAAATAG

Upstream 100 bases:

>100_bases
TGAAATATTTTACATTTCTTACTTTATCTCTTTCTTTTGATGATGTAACTCTGTGAAATAATTTTAAATTTGCATTCATA
AAAAACAACACAACAAGATA

Downstream 100 bases:

>100_bases
TAATTTTCGGGTTTAAACTAACTATTTAAACCATGAAAACTAACTTAAATAAAACAAATGCCTTGTTATCTCTATTTATG
ATAACAGGGCATTTTCTTTT

Product: phosphoribosylaminoimidazole-succinocarboxamide synthase

Products: NA

Alternate protein names: SAICAR synthetase [H]

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MSNTITTTNFNFPNQKSVYRGKVREVYNINDELLVMVATDRLSAFDVVLPKGIPYKGQILNQIATKFMELTQDIVPNWLI
ATPDPNVAVGHLCEPFKVEMVIRGYLSGHAAREYAAGRKQICGVTMAEGLKENDKFPEPIITPTTKADNGSHDEDISREA
ILSKGIISEEDYLVLEKYTRALFQRGTEIAASRGLILVDTKYEFGKTKDGVIVLIDEIHTPDSSRYFYADGYAERQEKGE
EQKQLSKEFVRRWLIENGFQGQEGQQIPDMSDEYIESVSERYIELYENILGEKFVKADIDNIDQRIEKNVLQYLTSK

Sequences:

>Translated_317_residues
MSNTITTTNFNFPNQKSVYRGKVREVYNINDELLVMVATDRLSAFDVVLPKGIPYKGQILNQIATKFMELTQDIVPNWLI
ATPDPNVAVGHLCEPFKVEMVIRGYLSGHAAREYAAGRKQICGVTMAEGLKENDKFPEPIITPTTKADNGSHDEDISREA
ILSKGIISEEDYLVLEKYTRALFQRGTEIAASRGLILVDTKYEFGKTKDGVIVLIDEIHTPDSSRYFYADGYAERQEKGE
EQKQLSKEFVRRWLIENGFQGQEGQQIPDMSDEYIESVSERYIELYENILGEKFVKADIDNIDQRIEKNVLQYLTSK
>Mature_316_residues
SNTITTTNFNFPNQKSVYRGKVREVYNINDELLVMVATDRLSAFDVVLPKGIPYKGQILNQIATKFMELTQDIVPNWLIA
TPDPNVAVGHLCEPFKVEMVIRGYLSGHAAREYAAGRKQICGVTMAEGLKENDKFPEPIITPTTKADNGSHDEDISREAI
LSKGIISEEDYLVLEKYTRALFQRGTEIAASRGLILVDTKYEFGKTKDGVIVLIDEIHTPDSSRYFYADGYAERQEKGEE
QKQLSKEFVRRWLIENGFQGQEGQQIPDMSDEYIESVSERYIELYENILGEKFVKADIDNIDQRIEKNVLQYLTSK

Specific function: De novo purine biosynthesis; seventh step. [C]

COG id: COG0152

COG function: function code F; Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SAICAR synthetase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6319326, Length=300, Percent_Identity=33.3333333333333, Blast_Score=166, Evalue=3e-42,

Paralogues:

None

Copy number: 1680 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 13,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013816
- InterPro:   IPR001636
- InterPro:   IPR018236 [H]

Pfam domain/function: PF01259 SAICAR_synt [H]

EC number: =6.3.2.6 [H]

Molecular weight: Translated: 36112; Mature: 35981

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS01058 SAICAR_SYNTHETASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNTITTTNFNFPNQKSVYRGKVREVYNINDELLVMVATDRLSAFDVVLPKGIPYKGQIL
CCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCHHHEECCCCCCCHHHHH
NQIATKFMELTQDIVPNWLIATPDPNVAVGHLCEPFKVEMVIRGYLSGHAAREYAAGRKQ
HHHHHHHHHHHHHHCCCCEEECCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ICGVTMAEGLKENDKFPEPIITPTTKADNGSHDEDISREAILSKGIISEEDYLVLEKYTR
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHH
ALFQRGTEIAASRGLILVDTKYEFGKTKDGVIVLIDEIHTPDSSRYFYADGYAERQEKGE
HHHHCCHHHHHCCCEEEEECCCCCCCCCCCEEEEEECCCCCCCCCEEEECCHHHHHHCCH
EQKQLSKEFVRRWLIENGFQGQEGQQIPDMSDEYIESVSERYIELYENILGEKFVKADID
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NIDQRIEKNVLQYLTSK
HHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SNTITTTNFNFPNQKSVYRGKVREVYNINDELLVMVATDRLSAFDVVLPKGIPYKGQIL
CCCEEEEECCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCHHHEECCCCCCCHHHHH
NQIATKFMELTQDIVPNWLIATPDPNVAVGHLCEPFKVEMVIRGYLSGHAAREYAAGRKQ
HHHHHHHHHHHHHHCCCCEEECCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ICGVTMAEGLKENDKFPEPIITPTTKADNGSHDEDISREAILSKGIISEEDYLVLEKYTR
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHH
ALFQRGTEIAASRGLILVDTKYEFGKTKDGVIVLIDEIHTPDSSRYFYADGYAERQEKGE
HHHHCCHHHHHCCCEEEEECCCCCCCCCCCEEEEEECCCCCCCCCEEEECCHHHHHHCCH
EQKQLSKEFVRRWLIENGFQGQEGQQIPDMSDEYIESVSERYIELYENILGEKFVKADID
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NIDQRIEKNVLQYLTSK
HHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA