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The map label for this gene is insF1 [H]

Identifier: 146300391

GI number: 146300391

Start: 3133952

End: 3135073

Strand: Reverse

Name: insF1 [H]

Synonym: Fjoh_2636

Alternate gene names: 146300391

Gene position: 3135073-3133952 (Counterclockwise)

Preceding gene: 146300392

Following gene: 146300385

Centisome position: 51.42

GC content: 36.72

Gene sequence:

>1122_bases
GTGAAAAGAAAATATGAAGACCATTTTAAAGAGCAGGCCGTCAGGTTAAGTTTTGAGCGGGGGGAGATCAGCAGTGTCGA
GAGAGAGCTCGGCATAAATCGCACCAGCTTGGGCAAATGGCGGAAAAAATATGAACACCTAAAATTAGCACCGAAGGATG
CTGTAATTATAGAGCTCAACAAAAAAATTAAAGATTCGCTGCTTACACTTGAGATTTTAAAAAATGGCAGTGAGTTCGCC
GCTCAAGGAAAAGTAATGACTAAAAGATTCATTGAAAATAATTCATCGAAATATCCTATTGGTAAAATGTGTGCATTACT
GCAGATATCCCAGCGTGCCTATTACAAACTAAAAAAAAAGGAAATATCGGATAAGCAGTCTCAAATAATTCTCTTAAAAG
AAGAAGTTGCAGCGGTATATTATGAGTTTAAGAAAACATATGGATACAGGAAAATTGCAAAAGTACTTCAATGCCGGGGA
TTTAAAGTGGGAGAATCGCAGATTAGAATATACATGAATGCACTGGGACTGCGCCGAAGAGCTAAATCCAGATTCACTAT
AACAACTGATTCAGTTCACAATCATTATATTGCACAAAATATCTTAAACAGGGAATTCACAATTAATCAGCCCGCTAAAG
CATGGGTTTCAGACATTACCTATATCGCAGCAGAGAAAGGCTTCCTGTATCTTACAATCGTCTTGGATTTATTTGACAGG
AAAATCATTGGATGGAGTTTAGCAGACAGCATGAGCACAAAAGAAACTACTTTACCTGCTTGGGAAATGGCCGTTAAAAA
CAGGAATATTACTCAAGACTTAATTTTTCACTCTGACAGAGGGGTCCAATATGCCAATAAAATTTTTACTGAAACTTTAG
ACTCTTATAAATTTGTAAGACGCAGTATGAGCCGCAAGCAGAATCATAATGACAATGCAGTTTCCGAAAGCTTTTTCGGC
AATTTGAAAAGAGAACTAATTAACGGGAATAAGCCTCTTCCAAGAGAACAAATGAGAGTCCAAGTTTACCAGTACATTGA
AAACTGGTATAATAAAAAGAGAAGGCATTCATATCTAAATTATAGAACAATCGAAGAGTTTGACAAACTGCATTGCATAT
GA

Upstream 100 bases:

>100_bases
CAGTCTTCCAACAAAAAAGGATATGGAAGACAAAGTAGCTCACTATATTGAAAATCTCAATTCAAAAGTCGTAACGTTAT
AAATTATAAAACTTTAAGCT

Downstream 100 bases:

>100_bases
TTGCATTTCGGTCTTCATCTTTAAAATAATTTACGGGCAATAAGGGATAAATTATTTAATTATACACATACCGCAGCTTA
TTTAAAAAAACATCTTGAAA

Product: integrase catalytic subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 373; Mature: 373

Protein sequence:

>373_residues
MKRKYEDHFKEQAVRLSFERGEISSVERELGINRTSLGKWRKKYEHLKLAPKDAVIIELNKKIKDSLLTLEILKNGSEFA
AQGKVMTKRFIENNSSKYPIGKMCALLQISQRAYYKLKKKEISDKQSQIILLKEEVAAVYYEFKKTYGYRKIAKVLQCRG
FKVGESQIRIYMNALGLRRRAKSRFTITTDSVHNHYIAQNILNREFTINQPAKAWVSDITYIAAEKGFLYLTIVLDLFDR
KIIGWSLADSMSTKETTLPAWEMAVKNRNITQDLIFHSDRGVQYANKIFTETLDSYKFVRRSMSRKQNHNDNAVSESFFG
NLKRELINGNKPLPREQMRVQVYQYIENWYNKKRRHSYLNYRTIEEFDKLHCI

Sequences:

>Translated_373_residues
MKRKYEDHFKEQAVRLSFERGEISSVERELGINRTSLGKWRKKYEHLKLAPKDAVIIELNKKIKDSLLTLEILKNGSEFA
AQGKVMTKRFIENNSSKYPIGKMCALLQISQRAYYKLKKKEISDKQSQIILLKEEVAAVYYEFKKTYGYRKIAKVLQCRG
FKVGESQIRIYMNALGLRRRAKSRFTITTDSVHNHYIAQNILNREFTINQPAKAWVSDITYIAAEKGFLYLTIVLDLFDR
KIIGWSLADSMSTKETTLPAWEMAVKNRNITQDLIFHSDRGVQYANKIFTETLDSYKFVRRSMSRKQNHNDNAVSESFFG
NLKRELINGNKPLPREQMRVQVYQYIENWYNKKRRHSYLNYRTIEEFDKLHCI
>Mature_373_residues
MKRKYEDHFKEQAVRLSFERGEISSVERELGINRTSLGKWRKKYEHLKLAPKDAVIIELNKKIKDSLLTLEILKNGSEFA
AQGKVMTKRFIENNSSKYPIGKMCALLQISQRAYYKLKKKEISDKQSQIILLKEEVAAVYYEFKKTYGYRKIAKVLQCRG
FKVGESQIRIYMNALGLRRRAKSRFTITTDSVHNHYIAQNILNREFTINQPAKAWVSDITYIAAEKGFLYLTIVLDLFDR
KIIGWSLADSMSTKETTLPAWEMAVKNRNITQDLIFHSDRGVQYANKIFTETLDSYKFVRRSMSRKQNHNDNAVSESFFG
NLKRELINGNKPLPREQMRVQVYQYIENWYNKKRRHSYLNYRTIEEFDKLHCI

Specific function: Involved in the transposition of the insertion sequence IS3 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=290, Percent_Identity=28.6206896551724, Blast_Score=124, Evalue=1e-28,
Organism=Escherichia coli, GI1788405, Length=281, Percent_Identity=32.7402135231317, Blast_Score=168, Evalue=5e-43,
Organism=Escherichia coli, GI1787263, Length=281, Percent_Identity=32.7402135231317, Blast_Score=168, Evalue=5e-43,
Organism=Escherichia coli, GI1786753, Length=281, Percent_Identity=32.7402135231317, Blast_Score=168, Evalue=5e-43,
Organism=Escherichia coli, GI1786570, Length=281, Percent_Identity=32.7402135231317, Blast_Score=168, Evalue=5e-43,
Organism=Escherichia coli, GI1786490, Length=281, Percent_Identity=32.7402135231317, Blast_Score=168, Evalue=5e-43,
Organism=Escherichia coli, GI1789981, Length=261, Percent_Identity=31.4176245210728, Blast_Score=114, Evalue=7e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 44022; Mature: 44022

Theoretical pI: Translated: 10.36; Mature: 10.36

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRKYEDHFKEQAVRLSFERGEISSVERELGINRTSLGKWRKKYEHLKLAPKDAVIIELN
CCCCHHHHHHHHHHHHEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEEEC
KKIKDSLLTLEILKNGSEFAAQGKVMTKRFIENNSSKYPIGKMCALLQISQRAYYKLKKK
HHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
EISDKQSQIILLKEEVAAVYYEFKKTYGYRKIAKVLQCRGFKVGESQIRIYMNALGLRRR
HCCCCHHEEEEEHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
AKSRFTITTDSVHNHYIAQNILNREFTINQPAKAWVSDITYIAAEKGFLYLTIVLDLFDR
HCCCEEEEECCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCEEEHHHHHHHCC
KIIGWSLADSMSTKETTLPAWEMAVKNRNITQDLIFHSDRGVQYANKIFTETLDSYKFVR
HHHCHHHHCCCCCCCCCCCHHHHHHCCCCCHHHHHEECCCCHHHHHHHHHHHHHHHHHHH
RSMSRKQNHNDNAVSESFFGNLKRELINGNKPLPREQMRVQVYQYIENWYNKKRRHSYLN
HHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
YRTIEEFDKLHCI
CHHHHHHHHHCCC
>Mature Secondary Structure
MKRKYEDHFKEQAVRLSFERGEISSVERELGINRTSLGKWRKKYEHLKLAPKDAVIIELN
CCCCHHHHHHHHHHHHEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEEEC
KKIKDSLLTLEILKNGSEFAAQGKVMTKRFIENNSSKYPIGKMCALLQISQRAYYKLKKK
HHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
EISDKQSQIILLKEEVAAVYYEFKKTYGYRKIAKVLQCRGFKVGESQIRIYMNALGLRRR
HCCCCHHEEEEEHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
AKSRFTITTDSVHNHYIAQNILNREFTINQPAKAWVSDITYIAAEKGFLYLTIVLDLFDR
HCCCEEEEECCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCEEEHHHHHHHCC
KIIGWSLADSMSTKETTLPAWEMAVKNRNITQDLIFHSDRGVQYANKIFTETLDSYKFVR
HHHCHHHHCCCCCCCCCCCHHHHHHCCCCCHHHHHEECCCCHHHHHHHHHHHHHHHHHHH
RSMSRKQNHNDNAVSESFFGNLKRELINGNKPLPREQMRVQVYQYIENWYNKKRRHSYLN
HHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
YRTIEEFDKLHCI
CHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2987844; 9278503 [H]