Click here to switch to the map view.

The map label for this gene is lolD [H]

Identifier: 146300209

GI number: 146300209

Start: 2938819

End: 2939697

Strand: Reverse

Name: lolD [H]

Synonym: Fjoh_2454

Alternate gene names: 146300209

Gene position: 2939697-2938819 (Counterclockwise)

Preceding gene: 146300211

Following gene: 146300208

Centisome position: 48.22

GC content: 34.02

Gene sequence:

>879_bases
ATGATACACGCAAAAAACATACATAAATTCTACGACAAACTTGAGGTTTTAAAAGGAGTTGATTTACATATTAAAAAAGG
CGAAATTGTTTCGATTGTCGGCGCTTCCGGAGCCGGAAAAACAACTTTACTGCAAATTTTAGGAACACTGGATAAACCTG
AAAGAAACCCAGATTCATCTTTAACTATAAATGGAGAAAACATTTTAAAACTGCAGGATATTGAAAACGATAATTCAAAA
CAAGAAAAAACTTTTAAAATCATAACCTGGGCAGGTTCTCTTTATATCATTATCCTGGCTGTTTATTTATTGTTTTTTAA
AACTAAAATTTTCGACGATACGTTACGCATAGTAGTAGTTACAGCTTTATTTTTACCTATAATTTCAATGCTTGTTTACT
ATAACAGATATTTTAAAAAGAAAAGCAAGCAAGACAAAATACTATCTGATTTTAGAAATTTAAATCTCGGATTCATTTTT
CAGTTTCACCAGTTACTGCCTGAATTTACTGCCTTAGAAAACGTTTGTATTCCCGCTTTTATGGCCAATAAACCAAAAGC
TGAAACCGAAAAAGAAGCAAAAAAAATCTTAGAATATTTAGGGTTGTCACACCGAATTAACCATAAACCCAACGAACTTT
CGGGTGGAGAACAGCAGCGTGTTGCTGTTGCAAGAGCCTTAATTAACAAACCCGATGTTATTTTTGCCGATGAGCCGTCT
GGAAATCTGGATACCCATTCTGCAGAAAATTTACATCAGTTGTTTTTTCAGCTTCGTGACGAATTCGGACAGACTTTTGT
AATCGTAACCCACAATGAGGAATTAGCCAATATGGCTGATAGAAAATTAATCATGGTCGACGGCCAGATTAGCAATTAA

Upstream 100 bases:

>100_bases
TTAAATTTAAATTGAAACAAAGCCAAAGTTTTGGAATTTAAAATATTGCAATTTGATTATAATTATAATCTTCGTTTCTT
TGTAAAAACAGTTTCACTAA

Downstream 100 bases:

>100_bases
GCATTCCCATCAAAATGAATCAAAAAGAACTCAAAGAATTTCTCGACGAGAAAGTCATACAATATAACAATCAGGATTTT
ATAGAAAGTGATCCTGTTCA

Product: ABC transporter-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MIHAKNIHKFYDKLEVLKGVDLHIKKGEIVSIVGASGAGKTTLLQILGTLDKPERNPDSSLTINGENILKLQDIENDNSK
QEKTFKIITWAGSLYIIILAVYLLFFKTKIFDDTLRIVVVTALFLPIISMLVYYNRYFKKKSKQDKILSDFRNLNLGFIF
QFHQLLPEFTALENVCIPAFMANKPKAETEKEAKKILEYLGLSHRINHKPNELSGGEQQRVAVARALINKPDVIFADEPS
GNLDTHSAENLHQLFFQLRDEFGQTFVIVTHNEELANMADRKLIMVDGQISN

Sequences:

>Translated_292_residues
MIHAKNIHKFYDKLEVLKGVDLHIKKGEIVSIVGASGAGKTTLLQILGTLDKPERNPDSSLTINGENILKLQDIENDNSK
QEKTFKIITWAGSLYIIILAVYLLFFKTKIFDDTLRIVVVTALFLPIISMLVYYNRYFKKKSKQDKILSDFRNLNLGFIF
QFHQLLPEFTALENVCIPAFMANKPKAETEKEAKKILEYLGLSHRINHKPNELSGGEQQRVAVARALINKPDVIFADEPS
GNLDTHSAENLHQLFFQLRDEFGQTFVIVTHNEELANMADRKLIMVDGQISN
>Mature_292_residues
MIHAKNIHKFYDKLEVLKGVDLHIKKGEIVSIVGASGAGKTTLLQILGTLDKPERNPDSSLTINGENILKLQDIENDNSK
QEKTFKIITWAGSLYIIILAVYLLFFKTKIFDDTLRIVVVTALFLPIISMLVYYNRYFKKKSKQDKILSDFRNLNLGFIF
QFHQLLPEFTALENVCIPAFMANKPKAETEKEAKKILEYLGLSHRINHKPNELSGGEQQRVAVARALINKPDVIFADEPS
GNLDTHSAENLHQLFFQLRDEFGQTFVIVTHNEELANMADRKLIMVDGQISN

Specific function: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-de

COG id: COG1136

COG function: function code V; ABC-type antimicrobial peptide transport system, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI215820660, Length=146, Percent_Identity=34.2465753424658, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI20143975, Length=146, Percent_Identity=34.2465753424658, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI105990541, Length=137, Percent_Identity=29.9270072992701, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI46592915, Length=146, Percent_Identity=32.1917808219178, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI46592898, Length=146, Percent_Identity=32.1917808219178, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI46592971, Length=146, Percent_Identity=32.1917808219178, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI46592956, Length=146, Percent_Identity=32.1917808219178, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI46592964, Length=146, Percent_Identity=32.1917808219178, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI46592978, Length=146, Percent_Identity=32.1917808219178, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI87081834, Length=173, Percent_Identity=44.5086705202312, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1786703, Length=142, Percent_Identity=47.887323943662, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI1787105, Length=143, Percent_Identity=44.7552447552448, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1788225, Length=151, Percent_Identity=39.0728476821192, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1787029, Length=139, Percent_Identity=43.8848920863309, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1789873, Length=141, Percent_Identity=38.2978723404255, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1787370, Length=133, Percent_Identity=39.0977443609023, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI1788761, Length=146, Percent_Identity=36.3013698630137, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1787712, Length=133, Percent_Identity=36.8421052631579, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1786872, Length=137, Percent_Identity=36.4963503649635, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1786398, Length=136, Percent_Identity=31.6176470588235, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1790467, Length=139, Percent_Identity=30.9352517985612, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1787089, Length=158, Percent_Identity=36.7088607594937, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1789672, Length=148, Percent_Identity=34.4594594594595, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1787164, Length=135, Percent_Identity=37.037037037037, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI87081791, Length=143, Percent_Identity=36.3636363636364, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1788450, Length=138, Percent_Identity=31.1594202898551, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI87081709, Length=137, Percent_Identity=35.036496350365, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1789032, Length=147, Percent_Identity=30.6122448979592, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87082267, Length=141, Percent_Identity=34.7517730496454, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1790534, Length=134, Percent_Identity=31.3432835820896, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1788644, Length=118, Percent_Identity=39.8305084745763, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1790544, Length=145, Percent_Identity=32.4137931034483, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787758, Length=141, Percent_Identity=31.9148936170213, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786563, Length=133, Percent_Identity=32.3308270676692, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI48994997, Length=177, Percent_Identity=31.0734463276836, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI145693107, Length=149, Percent_Identity=31.5436241610738, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1787500, Length=141, Percent_Identity=31.2056737588652, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI48994883, Length=111, Percent_Identity=32.4324324324324, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI48995001, Length=160, Percent_Identity=28.75, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1786253, Length=135, Percent_Identity=28.1481481481481, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1788506, Length=86, Percent_Identity=36.046511627907, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1789864, Length=147, Percent_Identity=25.1700680272109, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1789962, Length=107, Percent_Identity=30.8411214953271, Blast_Score=62, Evalue=3e-11,
Organism=Drosophila melanogaster, GI19920532, Length=99, Percent_Identity=37.3737373737374, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24580930, Length=99, Percent_Identity=37.3737373737374, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR015854
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 33215; Mature: 33215

Theoretical pI: Translated: 8.42; Mature: 8.42

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIHAKNIHKFYDKLEVLKGVDLHIKKGEIVSIVGASGAGKTTLLQILGTLDKPERNPDSS
CCCCHHHHHHHHHHHHHCCCCEEEECCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCE
LTINGENILKLQDIENDNSKQEKTFKIITWAGSLYIIILAVYLLFFKTKIFDDTLRIVVV
EEECCCCEEEEECCCCCCCCCHHEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TALFLPIISMLVYYNRYFKKKSKQDKILSDFRNLNLGFIFQFHQLLPEFTALENVCIPAF
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
MANKPKAETEKEAKKILEYLGLSHRINHKPNELSGGEQQRVAVARALINKPDVIFADEPS
HCCCCCCCHHHHHHHHHHHHCCHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCC
GNLDTHSAENLHQLFFQLRDEFGQTFVIVTHNEELANMADRKLIMVDGQISN
CCCCCCCHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHCCCEEEEECCCCCC
>Mature Secondary Structure
MIHAKNIHKFYDKLEVLKGVDLHIKKGEIVSIVGASGAGKTTLLQILGTLDKPERNPDSS
CCCCHHHHHHHHHHHHHCCCCEEEECCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCE
LTINGENILKLQDIENDNSKQEKTFKIITWAGSLYIIILAVYLLFFKTKIFDDTLRIVVV
EEECCCCEEEEECCCCCCCCCHHEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TALFLPIISMLVYYNRYFKKKSKQDKILSDFRNLNLGFIFQFHQLLPEFTALENVCIPAF
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
MANKPKAETEKEAKKILEYLGLSHRINHKPNELSGGEQQRVAVARALINKPDVIFADEPS
HCCCCCCCHHHHHHHHHHHHCCHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCC
GNLDTHSAENLHQLFFQLRDEFGQTFVIVTHNEELANMADRKLIMVDGQISN
CCCCCCCHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA