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The map label for this gene is flmA [H]

Identifier: 146284584

GI number: 146284584

Start: 87429

End: 87587

Strand: Direct

Name: flmA [H]

Synonym: Ent638_4258

Alternate gene names: 146284584

Gene position: 87429-87587 (Clockwise)

Preceding gene: 146284583

Following gene: 146284585

Centisome position: 55.42

GC content: 47.17

Gene sequence:

>159_bases
ATGAAACTGCCACGAAGTTCCCTTATCTGGTGCGTATTAATAGTGTGTCTCACACTGCTGATATTCACATTCCTGACACG
AAAATCGCTCTGCGAAATTCGTTATAAGGACGGAGACAGGGAGGTGGCGGCTTTCATGGCCTACGAATCCGGTAAGTAG

Upstream 100 bases:

>100_bases
CTGTCCAACTTTTTGGGGTCAGTACAACACTAGGCCATCTGCTTGACTAGACACCATCAGAATAGCCTCTTAGCCGCCGC
ACGGCAAGGAGAAGAAGGCT

Downstream 100 bases:

>100_bases
CAACCTGGAGGCGGGGGAAACCCCGCCTTTTCAGGAGCTGATGATGTCTGGATTTGCCTGAAGCGCCTTTATGAAGGGGC
TACCGGTTCGCTGGTAGCCC

Product: small toxic polypeptide

Products: NA

Alternate protein names: F leading maintenance protein [H]

Number of amino acids: Translated: 52; Mature: 52

Protein sequence:

>52_residues
MKLPRSSLIWCVLIVCLTLLIFTFLTRKSLCEIRYKDGDREVAAFMAYESGK

Sequences:

>Translated_52_residues
MKLPRSSLIWCVLIVCLTLLIFTFLTRKSLCEIRYKDGDREVAAFMAYESGK
>Mature_52_residues
MKLPRSSLIWCVLIVCLTLLIFTFLTRKSLCEIRYKDGDREVAAFMAYESGK

Specific function: FlmA extends the life of unstable plasmids [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hok/gef family [H]

Homologues:

Organism=Escherichia coli, GI48994884, Length=48, Percent_Identity=52.0833333333333, Blast_Score=59, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000021
- InterPro:   IPR018084
- ProDom:   PD005979 [H]

Pfam domain/function: PF01848 HOK_GEF [H]

EC number: NA

Molecular weight: Translated: 6030; Mature: 6030

Theoretical pI: Translated: 8.91; Mature: 8.91

Prosite motif: PS00556 HOK_GEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
9.6 %Cys+Met (Translated Protein)
5.8 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
9.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLPRSSLIWCVLIVCLTLLIFTFLTRKSLCEIRYKDGDREVAAFMAYESGK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure
MKLPRSSLIWCVLIVCLTLLIFTFLTRKSLCEIRYKDGDREVAAFMAYESGK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9722640; 9628576 [H]