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The map label for this gene is crr [H]

Identifier: 145299968

GI number: 145299968

Start: 3297094

End: 3297603

Strand: Direct

Name: crr [H]

Synonym: ASA_3062

Alternate gene names: 145299968

Gene position: 3297094-3297603 (Clockwise)

Preceding gene: 145299967

Following gene: 145299971

Centisome position: 70.12

GC content: 53.14

Gene sequence:

>510_bases
ATGGGTCTGTTTGATAAACTGAAGAAACTGGTTTCCGACGATAGCTCTGATACAGGCGGCATCGAAATTTTTGCCCCGCT
GTCAGGTGAAATCGTACCGATCGAAGATGTGCCTGACGTTGTCTTCGCCGAGAAGATCGTCGGCGACGGTATCGCCATCA
AGCCGGCTGGCAACAAGATGGTTGCACCGTGCGATGGTACCATCGGCAAGATCTTCGAGACCAACCACGCGTTCTCGCTG
GAATCCGACTCTGGTATCGAGCTGTTCGTTCACTTCGGTATCGATACCGTTGAACTGAAAGGCGAAGGCTTCACCCGCAT
CGCTCAGGAAGGTCAAAAGGTCAAGCGCGGCGACACCATCATCGAGTTCGATCTGGCCATTCTGGAAGCGAAAGCCAAGT
CTACCCTGACGCCGGTTGTCATCTCCAACATGGATGAGATCAAAGAGCTGATCAAGATGACGGGTGCCGTGACTGTGGGC
GAGACCCCGGTGATCCGCATCAAAAAATAA

Upstream 100 bases:

>100_bases
GCCGCCGAAATCGAAGCCTGTGTAGATAACTTTATTAAGCAGAAGGCAGTCTGCTAAGATCGGCTGCAAACAGCGACAAT
CATCTCTAGGAGCTTTTACT

Downstream 100 bases:

>100_bases
TGCACGGCTGGTTCAAGCCAGTTGCTGCAACGAAAAACCGAAGCCATGTGCTTCGGTTTTTTTATGAAAAAATGGCAGTG
AATACCGACTACTCCTTGCC

Product: PTS system glucose-specific transporter subunit

Products: protein histidine; sugar phosphate

Alternate protein names: EIIA-Glc; EIII-Glc; PTS system glucose-specific EIIA component [H]

Number of amino acids: Translated: 169; Mature: 168

Protein sequence:

>169_residues
MGLFDKLKKLVSDDSSDTGGIEIFAPLSGEIVPIEDVPDVVFAEKIVGDGIAIKPAGNKMVAPCDGTIGKIFETNHAFSL
ESDSGIELFVHFGIDTVELKGEGFTRIAQEGQKVKRGDTIIEFDLAILEAKAKSTLTPVVISNMDEIKELIKMTGAVTVG
ETPVIRIKK

Sequences:

>Translated_169_residues
MGLFDKLKKLVSDDSSDTGGIEIFAPLSGEIVPIEDVPDVVFAEKIVGDGIAIKPAGNKMVAPCDGTIGKIFETNHAFSL
ESDSGIELFVHFGIDTVELKGEGFTRIAQEGQKVKRGDTIIEFDLAILEAKAKSTLTPVVISNMDEIKELIKMTGAVTVG
ETPVIRIKK
>Mature_168_residues
GLFDKLKKLVSDDSSDTGGIEIFAPLSGEIVPIEDVPDVVFAEKIVGDGIAIKPAGNKMVAPCDGTIGKIFETNHAFSLE
SDSGIELFVHFGIDTVELKGEGFTRIAQEGQKVKRGDTIIEFDLAILEAKAKSTLTPVVISNMDEIKELIKMTGAVTVGE
TPVIRIKK

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG2190

COG function: function code G; Phosphotransferase system IIA components

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIA type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788757, Length=169, Percent_Identity=87.5739644970414, Blast_Score=291, Evalue=1e-80,
Organism=Escherichia coli, GI1786894, Length=149, Percent_Identity=49.6644295302013, Blast_Score=151, Evalue=2e-38,
Organism=Escherichia coli, GI1790159, Length=148, Percent_Identity=39.1891891891892, Blast_Score=107, Evalue=3e-25,

Paralogues:

None

Copy number: 3540 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 140 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR001127 [H]

Pfam domain/function: PF00358 PTS_EIIA_1 [H]

EC number: 2.7.1.69

Molecular weight: Translated: 18118; Mature: 17987

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: PS00371 PTS_EIIA_TYPE_1_HIS ; PS51093 PTS_EIIA_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLFDKLKKLVSDDSSDTGGIEIFAPLSGEIVPIEDVPDVVFAEKIVGDGIAIKPAGNKM
CCHHHHHHHHHCCCCCCCCCEEEEECCCCCEEECCCCCCHHHHHHHHCCCEEEECCCCEE
VAPCDGTIGKIFETNHAFSLESDSGIELFVHFGIDTVELKGEGFTRIAQEGQKVKRGDTI
EECCCCCCCCEEECCCEEEECCCCCEEEEEEECCEEEEECCCCHHHHHHCCCHHHCCCEE
IEFDLAILEAKAKSTLTPVVISNMDEIKELIKMTGAVTVGETPVIRIKK
EEEHHHEEHHHCCCCCCHHEECCHHHHHHHHHHHCCEEECCCCEEEEEC
>Mature Secondary Structure 
GLFDKLKKLVSDDSSDTGGIEIFAPLSGEIVPIEDVPDVVFAEKIVGDGIAIKPAGNKM
CHHHHHHHHHCCCCCCCCCEEEEECCCCCEEECCCCCCHHHHHHHHCCCEEEECCCCEE
VAPCDGTIGKIFETNHAFSLESDSGIELFVHFGIDTVELKGEGFTRIAQEGQKVKRGDTI
EECCCCCCCCEEECCCEEEECCCCCEEEEEEECCEEEEECCCCHHHHHHCCCHHHCCCEE
IEFDLAILEAKAKSTLTPVVISNMDEIKELIKMTGAVTVGETPVIRIKK
EEEHHHEEHHHCCCCCCHHEECCHHHHHHHHHHHCCEEECCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein N(pi)-phosphohistidine; sugar

Specific reaction: protein N(pi)-phosphohistidine + sugar = protein histidine + sugar phosphate

General reaction: Transferring phosphorus-containing groups; Phosphotransferases with an alcohol group as acceptor [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]