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The map label for this gene is ychM [C]

Identifier: 145299785

GI number: 145299785

Start: 3083929

End: 3085647

Strand: Direct

Name: ychM [C]

Synonym: ASA_2865

Alternate gene names: 145299785

Gene position: 3083929-3085647 (Clockwise)

Preceding gene: 145299784

Following gene: 145299786

Centisome position: 65.58

GC content: 63.99

Gene sequence:

>1719_bases
ATGCGCGACTTCTTCTCTCTCGAACGCTGGCTACCGGGCCTCGCCGGCGTGGGGCCCCTGGTTGGCCTCTACTCCTGCAT
ACTGCCCATGCTGGTCTATGCCCTGTTTGGCACCTCCCGCCAGCTCATCGTCGGCCCGGATGCCGCCACCTGCGCAGTGA
TCGCCGCCGTGGTGACCCCGCTAGCCGCCGGTGATGCTACCCGCCACTGGCAACTGGTGATGACCATGACCGCCATGACG
GGTTTCTGGTGCCTCATCGCCAGCCGCTTCAAGCTGGGGGTGCTGGCGGACTTTCTCTCCCGTCCCATACTGATGGGGCT
GCTCAACGGGGTGGCCATCACCATCATGGTGGGGCAGCTCTCCAAGATCTTCGGATTTACCTTCGATGAGCGTTACCTCA
TAGAGCGGATCGCCAGCGGGGCCTACTACATCACTCAAACCCATCTGCCGACCCTGGCCATGAGCCTGACCGCCTTGCTC
ACCCTGCTGCTGGCCAAACGTTACAAGCCTGCCTGGCCCTCCTCCATGGTGGCCATGGTGGTGACGGGGGCGCTGGTATG
GGGTTTCAGCCTTGGGGATCACGAAATCGCCACCCTCGGTCTGGTGGGTTCGGGCCTGCCCGCGTTTCAGCTCCCCCAGT
TTCCTCCCGGCCTGATGCGCGAACTGGTGCTGCCCGCCTTGAACCTTGCCATGGTGAGCTTCGTCTCCATGATGCTCACC
GCCCGCAGCTTCGCCGCCAAAAACGGCTACGAAATAGATGCGGACAAGGAGTTTCGGGCCCTTGGCATGGCCAATCTGGC
GGCCGCCGCCTCCCAGGGCTTTGCCATCAGTGGCGCCGATTCTCGCACCGCGGTCAACGATGCCAACGGCGGCAAGAGCC
AGCTGGTCTCCATCATAGCCGCCGCCGTGATCGCCATCATCACCTTCTACCTGACGGCGCCGCTGCAATACATACCCACG
GCCGCCCTCGGCGTTGTGCTGGTGATGGCGGCGCTGTCGCTCACCGACTTTCGCAGCCTGTGGGCCCTGCGCCATTCCGA
CAGATCCGCCTTCTGGCTCGCGCTCATCACCTTCATCAGCGTGCTGGCCATGGGGGTGATCCCGGGGATCACCCTCGCCG
TCTTGCTGGGTCTGTTCCAGTTCCTGCGCAACGTGATGCGCCCCACCGATCAACTGCTCGGCATGGATGACGAGGGGGTA
GTACGCACCCTGGGGGACAACGAACAGGCCAAGGCCATTCCCGGCATCCTGGTCTATCGCTTCAACTCGCCGCTCACCTA
CTTCAACGCCCCCTACTTCAAACGGCGGGTATTGGCGCTGCTGGTACAGGATCCCCACAATCCCAAGTGCCTGGTGGTGG
ATGCGGTGGCCTGTTTCACCCATCAGGACATCAGCGTGATGAGCATGGTGGGGGAGCTGCACAGGGATCTGAAACGGCGC
GGCATTCACATGGTGATGGCGGGTCGCCACGGCCAGATGAGCCAGTGGCTCAAGCAGGCGGGGATCCGGGTGGGCGACGA
GGGTGTCATCCTCTGCCCCGACATGTATCAGGCGCTGCGCATGACCCGCTGCTACCGCGAGCCTGTGTTCAAGGATGACG
CCGTGGTGGAGAGCACCACTGACGCCATCCTCTCCCACTGGCCCCAGGATGATGCCCTGCCGGACTCGGCGCGGCTCACC
CTGCCCTCCGAGCAGGAGGCGGGCGCCACCCTAGCCTGA

Upstream 100 bases:

>100_bases
TGGCCTGACCTTGTAGTGAACTGGCCATAACCGCATTGCAATGTTTCGGCAACCTTGGGCACACTAGGGAAAAGCTGTTT
GTAACTCAATGGGTTAAATA

Downstream 100 bases:

>100_bases
TCGGTTGCCAGACCATGCCCAGGGCTGGTCTGGCACACTCTCCTCCCAAGGCAAGATTGCACCCCGCAGGCTCTTGGTGT
TAAATGCCCGTCCAGATGGC

Product: sulfate permease family protein

Products: Proton [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 572; Mature: 572

Protein sequence:

>572_residues
MRDFFSLERWLPGLAGVGPLVGLYSCILPMLVYALFGTSRQLIVGPDAATCAVIAAVVTPLAAGDATRHWQLVMTMTAMT
GFWCLIASRFKLGVLADFLSRPILMGLLNGVAITIMVGQLSKIFGFTFDERYLIERIASGAYYITQTHLPTLAMSLTALL
TLLLAKRYKPAWPSSMVAMVVTGALVWGFSLGDHEIATLGLVGSGLPAFQLPQFPPGLMRELVLPALNLAMVSFVSMMLT
ARSFAAKNGYEIDADKEFRALGMANLAAAASQGFAISGADSRTAVNDANGGKSQLVSIIAAAVIAIITFYLTAPLQYIPT
AALGVVLVMAALSLTDFRSLWALRHSDRSAFWLALITFISVLAMGVIPGITLAVLLGLFQFLRNVMRPTDQLLGMDDEGV
VRTLGDNEQAKAIPGILVYRFNSPLTYFNAPYFKRRVLALLVQDPHNPKCLVVDAVACFTHQDISVMSMVGELHRDLKRR
GIHMVMAGRHGQMSQWLKQAGIRVGDEGVILCPDMYQALRMTRCYREPVFKDDAVVESTTDAILSHWPQDDALPDSARLT
LPSEQEAGATLA

Sequences:

>Translated_572_residues
MRDFFSLERWLPGLAGVGPLVGLYSCILPMLVYALFGTSRQLIVGPDAATCAVIAAVVTPLAAGDATRHWQLVMTMTAMT
GFWCLIASRFKLGVLADFLSRPILMGLLNGVAITIMVGQLSKIFGFTFDERYLIERIASGAYYITQTHLPTLAMSLTALL
TLLLAKRYKPAWPSSMVAMVVTGALVWGFSLGDHEIATLGLVGSGLPAFQLPQFPPGLMRELVLPALNLAMVSFVSMMLT
ARSFAAKNGYEIDADKEFRALGMANLAAAASQGFAISGADSRTAVNDANGGKSQLVSIIAAAVIAIITFYLTAPLQYIPT
AALGVVLVMAALSLTDFRSLWALRHSDRSAFWLALITFISVLAMGVIPGITLAVLLGLFQFLRNVMRPTDQLLGMDDEGV
VRTLGDNEQAKAIPGILVYRFNSPLTYFNAPYFKRRVLALLVQDPHNPKCLVVDAVACFTHQDISVMSMVGELHRDLKRR
GIHMVMAGRHGQMSQWLKQAGIRVGDEGVILCPDMYQALRMTRCYREPVFKDDAVVESTTDAILSHWPQDDALPDSARLT
LPSEQEAGATLA
>Mature_572_residues
MRDFFSLERWLPGLAGVGPLVGLYSCILPMLVYALFGTSRQLIVGPDAATCAVIAAVVTPLAAGDATRHWQLVMTMTAMT
GFWCLIASRFKLGVLADFLSRPILMGLLNGVAITIMVGQLSKIFGFTFDERYLIERIASGAYYITQTHLPTLAMSLTALL
TLLLAKRYKPAWPSSMVAMVVTGALVWGFSLGDHEIATLGLVGSGLPAFQLPQFPPGLMRELVLPALNLAMVSFVSMMLT
ARSFAAKNGYEIDADKEFRALGMANLAAAASQGFAISGADSRTAVNDANGGKSQLVSIIAAAVIAIITFYLTAPLQYIPT
AALGVVLVMAALSLTDFRSLWALRHSDRSAFWLALITFISVLAMGVIPGITLAVLLGLFQFLRNVMRPTDQLLGMDDEGV
VRTLGDNEQAKAIPGILVYRFNSPLTYFNAPYFKRRVLALLVQDPHNPKCLVVDAVACFTHQDISVMSMVGELHRDLKRR
GIHMVMAGRHGQMSQWLKQAGIRVGDEGVILCPDMYQALRMTRCYREPVFKDDAVVESTTDAILSHWPQDDALPDSARLT
LPSEQEAGATLA

Specific function: Expression in E.coli induces sulfate uptake during early-to mid-log phase growth. Uptake is maximal at pH 6.0, is sulfate-specific, requires E.coli CysA and the transmembrane segment but not the STAS domain of the protein [H]

COG id: COG0659

COG function: function code P; Sulfate permease and related transporters (MFS superfamily)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

Organism=Homo sapiens, GI94721255, Length=452, Percent_Identity=25.8849557522124, Blast_Score=150, Evalue=4e-36,
Organism=Homo sapiens, GI94721253, Length=452, Percent_Identity=25.8849557522124, Blast_Score=150, Evalue=4e-36,
Organism=Homo sapiens, GI94721257, Length=453, Percent_Identity=25.8278145695364, Blast_Score=149, Evalue=5e-36,
Organism=Homo sapiens, GI94721259, Length=452, Percent_Identity=25.8849557522124, Blast_Score=149, Evalue=5e-36,
Organism=Homo sapiens, GI45827800, Length=460, Percent_Identity=27.1739130434783, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI39752683, Length=464, Percent_Identity=26.9396551724138, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI269784651, Length=456, Percent_Identity=26.0964912280702, Blast_Score=132, Evalue=1e-30,
Organism=Homo sapiens, GI4557535, Length=468, Percent_Identity=25.6410256410256, Blast_Score=127, Evalue=3e-29,
Organism=Homo sapiens, GI4505697, Length=463, Percent_Identity=24.8380129589633, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI45827802, Length=407, Percent_Identity=27.2727272727273, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI262206105, Length=518, Percent_Identity=24.3243243243243, Blast_Score=116, Evalue=7e-26,
Organism=Homo sapiens, GI262206075, Length=518, Percent_Identity=24.3243243243243, Blast_Score=116, Evalue=7e-26,
Organism=Homo sapiens, GI262206069, Length=518, Percent_Identity=24.3243243243243, Blast_Score=116, Evalue=7e-26,
Organism=Homo sapiens, GI262206063, Length=518, Percent_Identity=24.3243243243243, Blast_Score=116, Evalue=7e-26,
Organism=Homo sapiens, GI100913030, Length=589, Percent_Identity=22.9202037351443, Blast_Score=110, Evalue=5e-24,
Organism=Homo sapiens, GI16418413, Length=472, Percent_Identity=24.1525423728814, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI217272867, Length=472, Percent_Identity=24.1525423728814, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI16418457, Length=458, Percent_Identity=22.2707423580786, Blast_Score=106, Evalue=7e-23,
Organism=Homo sapiens, GI301601599, Length=458, Percent_Identity=22.2707423580786, Blast_Score=106, Evalue=7e-23,
Organism=Homo sapiens, GI47131207, Length=479, Percent_Identity=25.4697286012526, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI20336272, Length=479, Percent_Identity=25.4697286012526, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI20336282, Length=548, Percent_Identity=19.8905109489051, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI16306483, Length=548, Percent_Identity=19.8905109489051, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI301601602, Length=237, Percent_Identity=24.0506329113924, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI65506789, Length=364, Percent_Identity=25.8241758241758, Blast_Score=73, Evalue=8e-13,
Organism=Escherichia coli, GI87081859, Length=401, Percent_Identity=21.1970074812968, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI86565215, Length=523, Percent_Identity=23.7093690248566, Blast_Score=135, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI17551690, Length=554, Percent_Identity=22.9241877256318, Blast_Score=134, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI86564196, Length=462, Percent_Identity=23.8095238095238, Blast_Score=115, Evalue=8e-26,
Organism=Caenorhabditis elegans, GI193203292, Length=477, Percent_Identity=25.5765199161426, Blast_Score=109, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17566848, Length=517, Percent_Identity=21.2765957446809, Blast_Score=100, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17562578, Length=623, Percent_Identity=21.0272873194222, Blast_Score=95, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI86564876, Length=367, Percent_Identity=21.7983651226158, Blast_Score=93, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6325260, Length=550, Percent_Identity=22.1818181818182, Blast_Score=102, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6323121, Length=419, Percent_Identity=24.3436754176611, Blast_Score=96, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6319771, Length=575, Percent_Identity=22.9565217391304, Blast_Score=93, Evalue=9e-20,
Organism=Drosophila melanogaster, GI24666186, Length=497, Percent_Identity=21.9315895372233, Blast_Score=112, Evalue=6e-25,
Organism=Drosophila melanogaster, GI24649801, Length=417, Percent_Identity=25.1798561151079, Blast_Score=112, Evalue=6e-25,
Organism=Drosophila melanogaster, GI21358229, Length=423, Percent_Identity=25.0591016548463, Blast_Score=107, Evalue=3e-23,
Organism=Drosophila melanogaster, GI85815873, Length=422, Percent_Identity=25.1184834123223, Blast_Score=105, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24651449, Length=436, Percent_Identity=20.6422018348624, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI19922482, Length=493, Percent_Identity=23.1237322515213, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI24663084, Length=543, Percent_Identity=23.7569060773481, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI21357695, Length=543, Percent_Identity=23.7569060773481, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24647160, Length=410, Percent_Identity=24.1463414634146, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI21355087, Length=410, Percent_Identity=24.1463414634146, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI21358633, Length=428, Percent_Identity=22.4299065420561, Blast_Score=82, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645
- InterPro:   IPR001902
- InterPro:   IPR011547 [H]

Pfam domain/function: PF01740 STAS; PF00916 Sulfate_transp [H]

EC number: NA

Molecular weight: Translated: 62096; Mature: 62096

Theoretical pI: Translated: 7.83; Mature: 7.83

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDFFSLERWLPGLAGVGPLVGLYSCILPMLVYALFGTSRQLIVGPDAATCAVIAAVVTP
CCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHH
LAAGDATRHWQLVMTMTAMTGFWCLIASRFKLGVLADFLSRPILMGLLNGVAITIMVGQL
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SKIFGFTFDERYLIERIASGAYYITQTHLPTLAMSLTALLTLLLAKRYKPAWPSSMVAMV
HHHHCCCCCHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
VTGALVWGFSLGDHEIATLGLVGSGLPAFQLPQFPPGLMRELVLPALNLAMVSFVSMMLT
HHHHHHHHCCCCCCHHEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ARSFAAKNGYEIDADKEFRALGMANLAAAASQGFAISGADSRTAVNDANGGKSQLVSIIA
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCHHHHHHHHH
AAVIAIITFYLTAPLQYIPTAALGVVLVMAALSLTDFRSLWALRHSDRSAFWLALITFIS
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
VLAMGVIPGITLAVLLGLFQFLRNVMRPTDQLLGMDDEGVVRTLGDNEQAKAIPGILVYR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCHHEECCCCCCHHCCCCEEEEE
FNSPLTYFNAPYFKRRVLALLVQDPHNPKCLVVDAVACFTHQDISVMSMVGELHRDLKRR
ECCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEHHHHHCCCCHHHHHHHHHHHHHHHHC
GIHMVMAGRHGQMSQWLKQAGIRVGDEGVILCPDMYQALRMTRCYREPVFKDDAVVESTT
CCEEEEECCCCHHHHHHHHCCCEECCCCEEECHHHHHHHHHHHHHHCCCCCCCCHHHHHH
DAILSHWPQDDALPDSARLTLPSEQEAGATLA
HHHHHHCCCCCCCCCCCEEECCCCCCCCCCCC
>Mature Secondary Structure
MRDFFSLERWLPGLAGVGPLVGLYSCILPMLVYALFGTSRQLIVGPDAATCAVIAAVVTP
CCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHH
LAAGDATRHWQLVMTMTAMTGFWCLIASRFKLGVLADFLSRPILMGLLNGVAITIMVGQL
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SKIFGFTFDERYLIERIASGAYYITQTHLPTLAMSLTALLTLLLAKRYKPAWPSSMVAMV
HHHHCCCCCHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
VTGALVWGFSLGDHEIATLGLVGSGLPAFQLPQFPPGLMRELVLPALNLAMVSFVSMMLT
HHHHHHHHCCCCCCHHEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ARSFAAKNGYEIDADKEFRALGMANLAAAASQGFAISGADSRTAVNDANGGKSQLVSIIA
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCHHHHHHHHH
AAVIAIITFYLTAPLQYIPTAALGVVLVMAALSLTDFRSLWALRHSDRSAFWLALITFIS
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
VLAMGVIPGITLAVLLGLFQFLRNVMRPTDQLLGMDDEGVVRTLGDNEQAKAIPGILVYR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCHHEECCCCCCHHCCCCEEEEE
FNSPLTYFNAPYFKRRVLALLVQDPHNPKCLVVDAVACFTHQDISVMSMVGELHRDLKRR
ECCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEHHHHHCCCCHHHHHHHHHHHHHHHHC
GIHMVMAGRHGQMSQWLKQAGIRVGDEGVILCPDMYQALRMTRCYREPVFKDDAVVESTT
CCEEEEECCCCHHHHHHHHCCCEECCCCEEECHHHHHHHHHHHHHHCCCCCCCCHHHHHH
DAILSHWPQDDALPDSARLTLPSEQEAGATLA
HHHHHHCCCCCCCCCCCEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; SO42- [Periplasm] [C]

Specific reaction: Proton [Periplasm] + SO42- [Periplasm] = Proton [Cytoplasm] + SO42- [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]