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The map label for this gene is nagA [H]

Identifier: 145299752

GI number: 145299752

Start: 3032525

End: 3033670

Strand: Direct

Name: nagA [H]

Synonym: ASA_2829

Alternate gene names: 145299752

Gene position: 3032525-3033670 (Clockwise)

Preceding gene: 145299751

Following gene: 145299753

Centisome position: 64.49

GC content: 59.95

Gene sequence:

>1146_bases
ATGTACGCATTGACCAATTGCACCCTCTACACCGGCAGCTGTGTGCTGACCGGTTACGGGGTCGTGATCGAGGGCGACAA
GATTGTCGCCATCCAGCGTCAGGCCGAGCTGCCTGCCGGTATAGAGCGACATGACCTGCACGGCGCCAACCTCTGCGCCG
GTTTTATCGACGTGCAGCTCAACGGCTGTGGCGGCGTCATGTTCAACACCGACATCTCCACAGAGACACTGGCGATCATG
CAGGCCGCCAACCTCAAATCCGGTACCACCAGCTTCCTGCCGACCCTGATCACCAGCCCGGATTCGGACATGAAGCGGGC
CGTCGCCGTGACCCGCGACTACATGGCCACGCACCCGAATGAAGTGCTGGGCGTGCATCTGGAAGGTCCCTACACCAACC
TCAAGCGCAAGGGCATTCACCCTGCCGCCCAGATCCGTCAGCCCGCCGACGAGATGATCGACTTCTTCTGTGCCAACAGC
GATGCCATCGCCAAGATCACCCTGGCACCGGAGCGCAACAAGCCCGAGCACATCCGTCAGCTGGTAGAGGCAGGCATACT
GGTCTCCGCTGGCCATACCGCCGCCAACTACGATCAGGCCATGGCCGGCTTTGATGACGGCATCCGCTTTGCCACCCACC
TCTACAACGCCATGACCCCGACCGTGAACGGCCGCGAGCCGGGTGTGGTGGGTGCCATCTATGATCGCAAGGATGTCTAT
GCTGGCGTCATCGTCGATGGACACCATGTGCACTGGGCCAACGTACGACTGGCCCACAAGATGCTGGGGGAGAGACTGGT
GCTGGTCACCGACGCGACCGCCCCCGCCGGTGCGCCGGAAGGCTTTGAGAAGTTTGATTTTTGTGGCGCAACCGTCTATT
TCCGCGATGGTCAGTGCGTCGACGAGAATGGTACACTCGGCGGCTCTGCCCTCACCATGATTGAGGGGGTGGAGAATCTG
GTCAAACAGGTCGGATTACCGCTCGATGAAGCACTGAGAATGGCCACTCTTTATCCCGCTCGCGCCATTGGATGGGACTC
ACGTCTCGGTAGTATCCAGGTCGGAAAAATAGCCAACCTGACTGTCTTTGATCAGACCTTCACGGTCTGCGGGACCGTGG
TTAACGGACACTACACAACACAGTGA

Upstream 100 bases:

>100_bases
GGTGTGCGACGAGCCCTCCACCATGGAGCTCAAGGTCAAGACGGTGCGTTACTTCCAGCAGCTCGAAGCCGCCAACATCG
GCCGTCTGTAAGGAGCCACC

Downstream 100 bases:

>100_bases
CACTATGACTGGCGGACAAATAGCAAACGTAGATCTTATCAAGCAGGTCAACAGTGCAGCCGTATATCGGCTCATCGACC
TGCAAGGCCCCATCTCGCGG

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MYALTNCTLYTGSCVLTGYGVVIEGDKIVAIQRQAELPAGIERHDLHGANLCAGFIDVQLNGCGGVMFNTDISTETLAIM
QAANLKSGTTSFLPTLITSPDSDMKRAVAVTRDYMATHPNEVLGVHLEGPYTNLKRKGIHPAAQIRQPADEMIDFFCANS
DAIAKITLAPERNKPEHIRQLVEAGILVSAGHTAANYDQAMAGFDDGIRFATHLYNAMTPTVNGREPGVVGAIYDRKDVY
AGVIVDGHHVHWANVRLAHKMLGERLVLVTDATAPAGAPEGFEKFDFCGATVYFRDGQCVDENGTLGGSALTMIEGVENL
VKQVGLPLDEALRMATLYPARAIGWDSRLGSIQVGKIANLTVFDQTFTVCGTVVNGHYTTQ

Sequences:

>Translated_381_residues
MYALTNCTLYTGSCVLTGYGVVIEGDKIVAIQRQAELPAGIERHDLHGANLCAGFIDVQLNGCGGVMFNTDISTETLAIM
QAANLKSGTTSFLPTLITSPDSDMKRAVAVTRDYMATHPNEVLGVHLEGPYTNLKRKGIHPAAQIRQPADEMIDFFCANS
DAIAKITLAPERNKPEHIRQLVEAGILVSAGHTAANYDQAMAGFDDGIRFATHLYNAMTPTVNGREPGVVGAIYDRKDVY
AGVIVDGHHVHWANVRLAHKMLGERLVLVTDATAPAGAPEGFEKFDFCGATVYFRDGQCVDENGTLGGSALTMIEGVENL
VKQVGLPLDEALRMATLYPARAIGWDSRLGSIQVGKIANLTVFDQTFTVCGTVVNGHYTTQ
>Mature_381_residues
MYALTNCTLYTGSCVLTGYGVVIEGDKIVAIQRQAELPAGIERHDLHGANLCAGFIDVQLNGCGGVMFNTDISTETLAIM
QAANLKSGTTSFLPTLITSPDSDMKRAVAVTRDYMATHPNEVLGVHLEGPYTNLKRKGIHPAAQIRQPADEMIDFFCANS
DAIAKITLAPERNKPEHIRQLVEAGILVSAGHTAANYDQAMAGFDDGIRFATHLYNAMTPTVNGREPGVVGAIYDRKDVY
AGVIVDGHHVHWANVRLAHKMLGERLVLVTDATAPAGAPEGFEKFDFCGATVYFRDGQCVDENGTLGGSALTMIEGVENL
VKQVGLPLDEALRMATLYPARAIGWDSRLGSIQVGKIANLTVFDQTFTVCGTVVNGHYTTQ

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=424, Percent_Identity=31.6037735849057, Blast_Score=166, Evalue=3e-41,
Organism=Homo sapiens, GI224922791, Length=419, Percent_Identity=31.7422434367542, Blast_Score=164, Evalue=2e-40,
Organism=Escherichia coli, GI1786892, Length=380, Percent_Identity=56.578947368421, Blast_Score=422, Evalue=1e-119,
Organism=Caenorhabditis elegans, GI17553768, Length=349, Percent_Identity=32.6647564469914, Blast_Score=160, Evalue=1e-39,
Organism=Drosophila melanogaster, GI19920392, Length=346, Percent_Identity=34.971098265896, Blast_Score=162, Evalue=5e-40,
Organism=Drosophila melanogaster, GI281361140, Length=359, Percent_Identity=33.7047353760446, Blast_Score=156, Evalue=3e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 40955; Mature: 40955

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYALTNCTLYTGSCVLTGYGVVIEGDKIVAIQRQAELPAGIERHDLHGANLCAGFIDVQL
CEEEEEEEEEECCEEEEECEEEEECCEEEEEEECCCCCCCCCCCCCCCCCEEEEEEEEEE
NGCGGVMFNTDISTETLAIMQAANLKSGTTSFLPTLITSPDSDMKRAVAVTRDYMATHPN
CCCCCEEEECCCCHHHEEEHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCC
EVLGVHLEGPYTNLKRKGIHPAAQIRQPADEMIDFFCANSDAIAKITLAPERNKPEHIRQ
CEEEEEECCCCCCHHHCCCCCHHHHCCCHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHH
LVEAGILVSAGHTAANYDQAMAGFDDGIRFATHLYNAMTPTVNGREPGVVGAIYDRKDVY
HHHCCEEEECCCCCCCHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCEE
AGVIVDGHHVHWANVRLAHKMLGERLVLVTDATAPAGAPEGFEKFDFCGATVYFRDGQCV
EEEEEECCEEEEEHHHHHHHHHCCEEEEEEECCCCCCCCCCCHHHHCCCEEEEEECCEEE
DENGTLGGSALTMIEGVENLVKQVGLPLDEALRMATLYPARAIGWDSRLGSIQVGKIANL
CCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHCCCCCCCCCEEECCEEEE
TVFDQTFTVCGTVVNGHYTTQ
EEECCHHEEHHHEECCEEECC
>Mature Secondary Structure
MYALTNCTLYTGSCVLTGYGVVIEGDKIVAIQRQAELPAGIERHDLHGANLCAGFIDVQL
CEEEEEEEEEECCEEEEECEEEEECCEEEEEEECCCCCCCCCCCCCCCCCEEEEEEEEEE
NGCGGVMFNTDISTETLAIMQAANLKSGTTSFLPTLITSPDSDMKRAVAVTRDYMATHPN
CCCCCEEEECCCCHHHEEEHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCC
EVLGVHLEGPYTNLKRKGIHPAAQIRQPADEMIDFFCANSDAIAKITLAPERNKPEHIRQ
CEEEEEECCCCCCHHHCCCCCHHHHCCCHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHH
LVEAGILVSAGHTAANYDQAMAGFDDGIRFATHLYNAMTPTVNGREPGVVGAIYDRKDVY
HHHCCEEEECCCCCCCHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCEE
AGVIVDGHHVHWANVRLAHKMLGERLVLVTDATAPAGAPEGFEKFDFCGATVYFRDGQCV
EEEEEECCEEEEEHHHHHHHHHCCEEEEEEECCCCCCCCCCCHHHHCCCEEEEEECCEEE
DENGTLGGSALTMIEGVENLVKQVGLPLDEALRMATLYPARAIGWDSRLGSIQVGKIANL
CCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHCCCCCCCCCEEECCEEEE
TVFDQTFTVCGTVVNGHYTTQ
EEECCHHEEHHHEECCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9301118; 10952301 [H]