Click here to switch to the map view.

The map label for this gene is nagC [H]

Identifier: 145299753

GI number: 145299753

Start: 3033675

End: 3034889

Strand: Direct

Name: nagC [H]

Synonym: ASA_2830

Alternate gene names: 145299753

Gene position: 3033675-3034889 (Clockwise)

Preceding gene: 145299752

Following gene: 145299754

Centisome position: 64.51

GC content: 59.75

Gene sequence:

>1215_bases
ATGACTGGCGGACAAATAGCAAACGTAGATCTTATCAAGCAGGTCAACAGTGCAGCCGTATATCGGCTCATCGACCTGCA
AGGCCCCATCTCGCGGGTCAAAATTGCCGAGTTGAGTCAGCTGGCCCCGGCCAGCGTGACCAAAATAACCCGGCAACTGA
TCGAGCATGGCCTGATCAAGGAGACCTCACCGCAAGCCTCTACCGGCGGGCGGCGTGCCATCTCCCTGACCACCATCAAG
CATCGCTTTCAGTTTGTGTCCGCCAAGCTCGGCCGCGGCTATCTGCAGCTGAGCCTGTACGATCTCGATGGCAAGGAGCT
CGATCAACACGTCACCCAGGTGACCGAGATCGATCAACAGCCTGTGGTCGACATGCTGCTGCGGGAAATTGGTGCCTTCA
TGGACTCCCAGCAGGAGCGCAACCGCAACCTGATCAGCATAGCGCTGACCATGCCGGGTCTGGTCAATCCGGAATCGGGT
ATGGTCATCTATACCCCCAAGTACCAGATCCGCAATCTGGCCCTGGCCAAGCTGCTGGAAAACCACTTCAACCTCCCCTG
CTACGTGGGCAACGACACCCGCTCACTGGCACTGGCCGAACACTTCTTCGGCGAGTCCCGCGACTGCATGGACTCCATTC
TGGTGAGCGTCCACCAGGGTGCCGGCTCCGGCATCATCACCAAGGGCAAGGTGTTCCTCGGTCAGAACCGCAACGTTGGC
GAGATCGGCCACATCCAGGTCGAACCGCTGGGCAAGCGCTGCCACTGCGGCAACTTTGGCTGCCTCGAGACCATCGCCTC
CAACGAGGCCATTGTCGACAAGGTAAAAGAGCTGATCAGTCGCGGTCACCTGAGCTCGCTGCAGGAGAAGCACATCACCA
TACAAGAGGTGTGCAAGGCGGCCATGGCAGGGGATGAGCTGGCACGCAGCGTGATCGAGAACGTGGGTGAGCACTTGGGA
CGGGCGGTGGCCATCACGGTCAACCTGTTCAACCCGCAGAAGGTGCTGATCGCAGGCGAAATCACTGCCGCCGAAGAGAT
CCTCTTCCCGGCCATTCGCCGCTGTGTCGAACACCAGTCACTGCCGAGCTTCCACCGTGGCCTGCCCATCGTGAAGGCCC
GCTTCCAGAACCAGCCCACCATAGGCGGTTTCGCCCTGGTGAAACGGGCCCTGCTGGAGGGAGACCTGCTGCAGATCATC
ATGGAGCAGAAATAA

Upstream 100 bases:

>100_bases
AGTATCCAGGTCGGAAAAATAGCCAACCTGACTGTCTTTGATCAGACCTTCACGGTCTGCGGGACCGTGGTTAACGGACA
CTACACAACACAGTGACACT

Downstream 100 bases:

>100_bases
TTGATGTATAATCTCGACATTGACTCATATATCTTGAGCTAAACACTCACAACTTAGAGCCCCGATATATCCCATCGGGG
TTCTATATCTAAATGTTAGA

Product: N-acetylglucosamine repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MTGGQIANVDLIKQVNSAAVYRLIDLQGPISRVKIAELSQLAPASVTKITRQLIEHGLIKETSPQASTGGRRAISLTTIK
HRFQFVSAKLGRGYLQLSLYDLDGKELDQHVTQVTEIDQQPVVDMLLREIGAFMDSQQERNRNLISIALTMPGLVNPESG
MVIYTPKYQIRNLALAKLLENHFNLPCYVGNDTRSLALAEHFFGESRDCMDSILVSVHQGAGSGIITKGKVFLGQNRNVG
EIGHIQVEPLGKRCHCGNFGCLETIASNEAIVDKVKELISRGHLSSLQEKHITIQEVCKAAMAGDELARSVIENVGEHLG
RAVAITVNLFNPQKVLIAGEITAAEEILFPAIRRCVEHQSLPSFHRGLPIVKARFQNQPTIGGFALVKRALLEGDLLQII
MEQK

Sequences:

>Translated_404_residues
MTGGQIANVDLIKQVNSAAVYRLIDLQGPISRVKIAELSQLAPASVTKITRQLIEHGLIKETSPQASTGGRRAISLTTIK
HRFQFVSAKLGRGYLQLSLYDLDGKELDQHVTQVTEIDQQPVVDMLLREIGAFMDSQQERNRNLISIALTMPGLVNPESG
MVIYTPKYQIRNLALAKLLENHFNLPCYVGNDTRSLALAEHFFGESRDCMDSILVSVHQGAGSGIITKGKVFLGQNRNVG
EIGHIQVEPLGKRCHCGNFGCLETIASNEAIVDKVKELISRGHLSSLQEKHITIQEVCKAAMAGDELARSVIENVGEHLG
RAVAITVNLFNPQKVLIAGEITAAEEILFPAIRRCVEHQSLPSFHRGLPIVKARFQNQPTIGGFALVKRALLEGDLLQII
MEQK
>Mature_403_residues
TGGQIANVDLIKQVNSAAVYRLIDLQGPISRVKIAELSQLAPASVTKITRQLIEHGLIKETSPQASTGGRRAISLTTIKH
RFQFVSAKLGRGYLQLSLYDLDGKELDQHVTQVTEIDQQPVVDMLLREIGAFMDSQQERNRNLISIALTMPGLVNPESGM
VIYTPKYQIRNLALAKLLENHFNLPCYVGNDTRSLALAEHFFGESRDCMDSILVSVHQGAGSGIITKGKVFLGQNRNVGE
IGHIQVEPLGKRCHCGNFGCLETIASNEAIVDKVKELISRGHLSSLQEKHITIQEVCKAAMAGDELARSVIENVGEHLGR
AVAITVNLFNPQKVLIAGEITAAEEILFPAIRRCVEHQSLPSFHRGLPIVKARFQNQPTIGGFALVKRALLEGDLLQIIM
EQK

Specific function: Acts as a repressor of the nagEBACD operon and acts both as an activator and a repressor for the transcription of the glmSU operon [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566325, Length=275, Percent_Identity=25.4545454545455, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI298566315, Length=271, Percent_Identity=25.830258302583, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI4885285, Length=271, Percent_Identity=25.830258302583, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI190014632, Length=271, Percent_Identity=25.830258302583, Blast_Score=80, Evalue=4e-15,
Organism=Escherichia coli, GI1786891, Length=405, Percent_Identity=56.5432098765432, Blast_Score=461, Evalue=1e-131,
Organism=Escherichia coli, GI1787878, Length=395, Percent_Identity=39.4936708860759, Blast_Score=310, Evalue=1e-85,
Organism=Escherichia coli, GI87082127, Length=241, Percent_Identity=27.8008298755187, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790522, Length=257, Percent_Identity=25.2918287937743, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI87082230, Length=194, Percent_Identity=30.9278350515464, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI87081733, Length=253, Percent_Identity=20.5533596837945, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000835
- InterPro:   IPR000600
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01047 MarR; PF00480 ROK [H]

EC number: NA

Molecular weight: Translated: 44386; Mature: 44255

Theoretical pI: Translated: 8.10; Mature: 8.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGGQIANVDLIKQVNSAAVYRLIDLQGPISRVKIAELSQLAPASVTKITRQLIEHGLIK
CCCCCCCCHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCC
ETSPQASTGGRRAISLTTIKHRFQFVSAKLGRGYLQLSLYDLDGKELDQHVTQVTEIDQQ
CCCCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCEEEEEEEECCHHHHHHHHHHHHHCCCC
PVVDMLLREIGAFMDSQQERNRNLISIALTMPGLVNPESGMVIYTPKYQIRNLALAKLLE
HHHHHHHHHHHHHHCCHHHHCCCEEEEEEECCCCCCCCCCEEEECCCHHHHHHHHHHHHH
NHFNLPCYVGNDTRSLALAEHFFGESRDCMDSILVSVHQGAGSGIITKGKVFLGQNRNVG
HHCCCCEEECCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEECEEEECCCCCCC
EIGHIQVEPLGKRCHCGNFGCLETIASNEAIVDKVKELISRGHLSSLQEKHITIQEVCKA
CCCEEEECCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHH
AMAGDELARSVIENVGEHLGRAVAITVNLFNPQKVLIAGEITAAEEILFPAIRRCVEHQS
HHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCEEEEEECCHHHHHHHHHHHHHHHHHCC
LPSFHRGLPIVKARFQNQPTIGGFALVKRALLEGDLLQIIMEQK
CCHHHHCCCHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHCCC
>Mature Secondary Structure 
TGGQIANVDLIKQVNSAAVYRLIDLQGPISRVKIAELSQLAPASVTKITRQLIEHGLIK
CCCCCCCHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCC
ETSPQASTGGRRAISLTTIKHRFQFVSAKLGRGYLQLSLYDLDGKELDQHVTQVTEIDQQ
CCCCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCEEEEEEEECCHHHHHHHHHHHHHCCCC
PVVDMLLREIGAFMDSQQERNRNLISIALTMPGLVNPESGMVIYTPKYQIRNLALAKLLE
HHHHHHHHHHHHHHCCHHHHCCCEEEEEEECCCCCCCCCCEEEECCCHHHHHHHHHHHHH
NHFNLPCYVGNDTRSLALAEHFFGESRDCMDSILVSVHQGAGSGIITKGKVFLGQNRNVG
HHCCCCEEECCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEECEEEECCCCCCC
EIGHIQVEPLGKRCHCGNFGCLETIASNEAIVDKVKELISRGHLSSLQEKHITIQEVCKA
CCCEEEECCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHH
AMAGDELARSVIENVGEHLGRAVAITVNLFNPQKVLIAGEITAAEEILFPAIRRCVEHQS
HHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCEEEEEECCHHHHHHHHHHHHHHHHHCC
LPSFHRGLPIVKARFQNQPTIGGFALVKRALLEGDLLQIIMEQK
CCHHHHCCCHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]