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The map label for this gene is 145296090

Identifier: 145296090

GI number: 145296090

Start: 2211000

End: 2212205

Strand: Reverse

Name: 145296090

Synonym: cgR_2012

Alternate gene names: NA

Gene position: 2212205-2211000 (Counterclockwise)

Preceding gene: 145296091

Following gene: 145296088

Centisome position: 66.75

GC content: 55.39

Gene sequence:

>1206_bases
ATGAGCCAGAACCGCATCAGGACCACTCACGTTGGTTCCTTGCCCCGTACCCCAGAGCTACTTGATGCAAACATCAAGCG
TTCTAACGGTGAGATTGGGGAGGAGGAATTCTTCCAGATTCTGCAGTCTTCTGTAGATGACGTGATCAAGCGCCAGGTTG
ACCTGGGTATCGACATCCTTAACGAGGGCGAATACGGCCACGTCACCTCCGGTGCAGTTGACTTCGGTGCATGGTGGAAC
TACTCCTTCACCCGCCTGGGCGGACTGACAATGACCGATACCGACCGTTGGGCAAGCCAGGAAGCAGTGCGTTCCACCCC
TGGCAACATCAAGCTGACCAGCTTCTCTGATCGTCGCGACCGCGCATTGTTCAGCGAAGCATACGAGGATCCAGTATCTG
GCATCTTCACCGGCCGCGCTTCTGTGGGCAACCCAGAGTTCACCGGACCTATTACCTACATTGGCCAGGAAGAAACTCAG
ACGGATGTTGATCTGCTGAAGAAGGGCATGAACGCAGCGGGAGCTACCGACGGCTTCGTTGCAGCACTATCCCCAGGATC
TGCAGCTCGATTGACCAACAAGTTCTACGACACTGATGAAGAAGTCGTCGCAGCATGTGCTGATGCGCTTTCCCAGGAAT
ACAAGATCATCACCGATGCAGGTCTGACCGTTCAGCTCGACGCACCGGACTTGGCAGAAGCATGGGATCAGATCAACCCA
GAGCCAAGCGTGAAGGATTACTTGGACTGGATCGGTACACGCATCGATGCCATCAACAGTGCAGTGAAGGGCCTTCCAAA
GGAACAGACCCGCCTGCACATCTGCTGGGGCTCTTGGCACGGACCACACGTCACTGACATCCCATTCGGTGACATCATTG
GTGAGATCCTGCGCGCAGAGGTCGGTGGCTTCTCCTTCGAAGGCGCATCTCCTCGTCACGCACACGAGTGGCGTGTATGG
GAAGAAAACAAGCTTCCTGAAGGCTCTGTTATCTACCCTGGTGTTGTGTCTCACTCCATCAACGCTGTGGAGCACCCACG
CCTGGTTGCTGATCGTATCGTTCAGTTCGCCAAGCTTGTTGGCCCTGAGAACGTCATTGCGTCCACTGACTGTGGTCTGG
GCGGACGTCTGCATTCCCAGATCGCATGGGCAAAGCTGGAGTCCCTAGTAGAGGGCGCTCGCATTGCATCAAAGGAACTG
TTCTAA

Upstream 100 bases:

>100_bases
ATGAATAAAATTCCGGGTGCAGTGACCGTAGGTGAGGTAAACGCGGTTAGAGTCGAATGAGAGTTTGATACTTTCTTTCG
ACTTTTAGATTGGATTTTCA

Downstream 100 bases:

>100_bases
GCTAGACAACGAGGGTTGCTAGTCTAAGCAGCAAAATGAGCGGCTGTTGTTCCTTCAGGAAAATTATCTGAAGGAACAAC
AGCCGCTCATTTTATGTCAG

Product: hypothetical protein

Products: tetrahydropteroyltri-L-glutamate; L-methionine

Alternate protein names: Methionine Synthase II; Methionine Synthase II- Like Protein; EpoxyalkaneCo M Transferase; Methyltransferase; Methionine Synthase Vitamin-B12 Independent Protein

Number of amino acids: Translated: 401; Mature: 400

Protein sequence:

>401_residues
MSQNRIRTTHVGSLPRTPELLDANIKRSNGEIGEEEFFQILQSSVDDVIKRQVDLGIDILNEGEYGHVTSGAVDFGAWWN
YSFTRLGGLTMTDTDRWASQEAVRSTPGNIKLTSFSDRRDRALFSEAYEDPVSGIFTGRASVGNPEFTGPITYIGQEETQ
TDVDLLKKGMNAAGATDGFVAALSPGSAARLTNKFYDTDEEVVAACADALSQEYKIITDAGLTVQLDAPDLAEAWDQINP
EPSVKDYLDWIGTRIDAINSAVKGLPKEQTRLHICWGSWHGPHVTDIPFGDIIGEILRAEVGGFSFEGASPRHAHEWRVW
EENKLPEGSVIYPGVVSHSINAVEHPRLVADRIVQFAKLVGPENVIASTDCGLGGRLHSQIAWAKLESLVEGARIASKEL
F

Sequences:

>Translated_401_residues
MSQNRIRTTHVGSLPRTPELLDANIKRSNGEIGEEEFFQILQSSVDDVIKRQVDLGIDILNEGEYGHVTSGAVDFGAWWN
YSFTRLGGLTMTDTDRWASQEAVRSTPGNIKLTSFSDRRDRALFSEAYEDPVSGIFTGRASVGNPEFTGPITYIGQEETQ
TDVDLLKKGMNAAGATDGFVAALSPGSAARLTNKFYDTDEEVVAACADALSQEYKIITDAGLTVQLDAPDLAEAWDQINP
EPSVKDYLDWIGTRIDAINSAVKGLPKEQTRLHICWGSWHGPHVTDIPFGDIIGEILRAEVGGFSFEGASPRHAHEWRVW
EENKLPEGSVIYPGVVSHSINAVEHPRLVADRIVQFAKLVGPENVIASTDCGLGGRLHSQIAWAKLESLVEGARIASKEL
F
>Mature_400_residues
SQNRIRTTHVGSLPRTPELLDANIKRSNGEIGEEEFFQILQSSVDDVIKRQVDLGIDILNEGEYGHVTSGAVDFGAWWNY
SFTRLGGLTMTDTDRWASQEAVRSTPGNIKLTSFSDRRDRALFSEAYEDPVSGIFTGRASVGNPEFTGPITYIGQEETQT
DVDLLKKGMNAAGATDGFVAALSPGSAARLTNKFYDTDEEVVAACADALSQEYKIITDAGLTVQLDAPDLAEAWDQINPE
PSVKDYLDWIGTRIDAINSAVKGLPKEQTRLHICWGSWHGPHVTDIPFGDIIGEILRAEVGGFSFEGASPRHAHEWRVWE
ENKLPEGSVIYPGVVSHSINAVEHPRLVADRIVQFAKLVGPENVIASTDCGLGGRLHSQIAWAKLESLVEGARIASKELF

Specific function: Unknown

COG id: COG0620

COG function: function code E; Methionine synthase II (cobalamin-independent)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.1.1.14

Molecular weight: Translated: 43895; Mature: 43764

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQNRIRTTHVGSLPRTPELLDANIKRSNGEIGEEEFFQILQSSVDDVIKRQVDLGIDIL
CCCCCEEEEECCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEE
NEGEYGHVTSGAVDFGAWWNYSFTRLGGLTMTDTDRWASQEAVRSTPGNIKLTSFSDRRD
CCCCCCCEECCCEECCCCCCCCHHHHCCEEECCCHHHHHHHHHHCCCCCEEEEECCCHHH
RALFSEAYEDPVSGIFTGRASVGNPEFTGPITYIGQEETQTDVDLLKKGMNAAGATDGFV
HHHHHHHHHCHHHHEEECCCCCCCCCCCCCEEECCCCCCHHHHHHHHHCCCCCCCCCCEE
AALSPGSAARLTNKFYDTDEEVVAACADALSQEYKIITDAGLTVQLDAPDLAEAWDQINP
EEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHCEEEEECCCCEEEECCCHHHHHHHHCCC
EPSVKDYLDWIGTRIDAINSAVKGLPKEQTRLHICWGSWHGPHVTDIPFGDIIGEILRAE
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHH
VGGFSFEGASPRHAHEWRVWEENKLPEGSVIYPGVVSHSINAVEHPRLVADRIVQFAKLV
HCCEECCCCCCCCCCCCCEECCCCCCCCCEECCCHHHHCCCHHCCHHHHHHHHHHHHHHC
GPENVIASTDCGLGGRLHSQIAWAKLESLVEGARIASKELF
CCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SQNRIRTTHVGSLPRTPELLDANIKRSNGEIGEEEFFQILQSSVDDVIKRQVDLGIDIL
CCCCEEEEECCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEE
NEGEYGHVTSGAVDFGAWWNYSFTRLGGLTMTDTDRWASQEAVRSTPGNIKLTSFSDRRD
CCCCCCCEECCCEECCCCCCCCHHHHCCEEECCCHHHHHHHHHHCCCCCEEEEECCCHHH
RALFSEAYEDPVSGIFTGRASVGNPEFTGPITYIGQEETQTDVDLLKKGMNAAGATDGFV
HHHHHHHHHCHHHHEEECCCCCCCCCCCCCEEECCCCCCHHHHHHHHHCCCCCCCCCCEE
AALSPGSAARLTNKFYDTDEEVVAACADALSQEYKIITDAGLTVQLDAPDLAEAWDQINP
EEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHCEEEEECCCCEEEECCCHHHHHHHHCCC
EPSVKDYLDWIGTRIDAINSAVKGLPKEQTRLHICWGSWHGPHVTDIPFGDIIGEILRAE
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHH
VGGFSFEGASPRHAHEWRVWEENKLPEGSVIYPGVVSHSINAVEHPRLVADRIVQFAKLV
HCCEECCCCCCCCCCCCCEECCCCCCCCCEECCCHHHHCCCHHCCHHHHHHHHHHHHHHC
GPENVIASTDCGLGGRLHSQIAWAKLESLVEGARIASKELF
CCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 5-methyltetrahydropteroyltri-L-glutamate; L-homocysteine

Specific reaction: 5-methyltetrahydropteroyltri-L-glutamate + L-homocysteine = tetrahydropteroyltri-L-glutamate + L-methionine

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA