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The map label for this gene is xerC [H]

Identifier: 145295931

GI number: 145295931

Start: 2060746

End: 2061693

Strand: Reverse

Name: xerC [H]

Synonym: cgR_1856

Alternate gene names: 145295931

Gene position: 2061693-2060746 (Counterclockwise)

Preceding gene: 145295932

Following gene: 145295929

Centisome position: 62.21

GC content: 52.43

Gene sequence:

>948_bases
ATGGGTGAGTCGAAAAAGAAGGCGGCGCGTTCCGGGCGGAACGCGCCACCTTCTGGTATTTCCGGCGCCGACGCGCCGTC
CAAGCTGCATACGCTTATCGACGATTTCTGTGAGCATCTAGACCTTGTGGTGGGTCGTTCAGCCGCAACAATTCGCGGAT
ATCGTTCAGACCTTTATGCCATGGCCGACACAATCGAAGATATCGACAATTTCTCCCTGCCGACTCTGCGCCAATGGCTT
GGTATAGCGGTAGATGAGGGAAAGTCCAGGGCAACACTCGCCAGAAGAACTGCATCTGTCAAGGCGTTTTCTTCATGGGC
TCAGAAAAACGGCCACCTCAAAGCTGATGAAGCAGCCCGACTCATTTCACCGAAGATCACGAGGGATCTACCTAAGATTC
TCGGGGAACAGCAGGCAGGAGACTTTGTAGAAAACGCAGCTTCCACAAATGAAGAAGAGTTCCTGCGTGATTCCGCGATT
CTGGAGCTTCTTTATGCCACGGGAATGCGTGTTGCTGAACTCTGTGGAATCGATCTTCCAGACATTGACTACGACCGCAA
AATGGTACGAGTGCTGGGTAAAGGAAATAAAGAGCGCGTTGTCCCATTCGGGGAATCGGCACACAAGGCGTTAAGAAATT
GGCTAGATGTGCGCGATGAGATGGCGGAAGATCCCAAAGCGCTCTTTGTTGGGGTGCGGGGTCAGCGAATTAATGCGCGC
CAAGTTCGAAGGATTGTTGATCGAGTGGCAAAAGTCACTGGCGTTGACCATTTGTCACCACACTCGCTGCGGCATACTGC
GGCAACTCACTTGCTGGACGGTGGGGCGGACCTTCGCCAGGTTCAAGAACTATTAGGGCACTCGTCAATGCAAACGACGC
AGATCTATACCCACGTCAGTAATAAGAGACTGCTTGAAGCGTTTAATAAAGCGCATCCACGTGCCTAG

Upstream 100 bases:

>100_bases
AAGCCTAAGTAAACTTCTTCAAGGTTCGGGCTGGTTCCTTGAAGACGGTTCCGCAATGTGGCTCCACAACTGTGGGGGAC
ATCGCGCTAGGGTTAGCACT

Downstream 100 bases:

>100_bases
TTAAGAGGTTTAAGGCGAATGGTTGGCCGGGGAAGTAGCGATAGGGGATTGATATATTCTTCACCTATTTTTGCGCCCCA
CTGAAGTCCAGGGAACTTAG

Product: site-specific tyrosine recombinase XerC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 314

Protein sequence:

>315_residues
MGESKKKAARSGRNAPPSGISGADAPSKLHTLIDDFCEHLDLVVGRSAATIRGYRSDLYAMADTIEDIDNFSLPTLRQWL
GIAVDEGKSRATLARRTASVKAFSSWAQKNGHLKADEAARLISPKITRDLPKILGEQQAGDFVENAASTNEEEFLRDSAI
LELLYATGMRVAELCGIDLPDIDYDRKMVRVLGKGNKERVVPFGESAHKALRNWLDVRDEMAEDPKALFVGVRGQRINAR
QVRRIVDRVAKVTGVDHLSPHSLRHTAATHLLDGGADLRQVQELLGHSSMQTTQIYTHVSNKRLLEAFNKAHPRA

Sequences:

>Translated_315_residues
MGESKKKAARSGRNAPPSGISGADAPSKLHTLIDDFCEHLDLVVGRSAATIRGYRSDLYAMADTIEDIDNFSLPTLRQWL
GIAVDEGKSRATLARRTASVKAFSSWAQKNGHLKADEAARLISPKITRDLPKILGEQQAGDFVENAASTNEEEFLRDSAI
LELLYATGMRVAELCGIDLPDIDYDRKMVRVLGKGNKERVVPFGESAHKALRNWLDVRDEMAEDPKALFVGVRGQRINAR
QVRRIVDRVAKVTGVDHLSPHSLRHTAATHLLDGGADLRQVQELLGHSSMQTTQIYTHVSNKRLLEAFNKAHPRA
>Mature_314_residues
GESKKKAARSGRNAPPSGISGADAPSKLHTLIDDFCEHLDLVVGRSAATIRGYRSDLYAMADTIEDIDNFSLPTLRQWLG
IAVDEGKSRATLARRTASVKAFSSWAQKNGHLKADEAARLISPKITRDLPKILGEQQAGDFVENAASTNEEEFLRDSAIL
ELLYATGMRVAELCGIDLPDIDYDRKMVRVLGKGNKERVVPFGESAHKALRNWLDVRDEMAEDPKALFVGVRGQRINARQ
VRRIVDRVAKVTGVDHLSPHSLRHTAATHLLDGGADLRQVQELLGHSSMQTTQIYTHVSNKRLLEAFNKAHPRA

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790244, Length=295, Percent_Identity=34.2372881355932, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI1789261, Length=295, Percent_Identity=37.9661016949153, Blast_Score=171, Evalue=7e-44,
Organism=Escherichia coli, GI1790767, Length=163, Percent_Identity=26.9938650306748, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790768, Length=147, Percent_Identity=32.6530612244898, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 34790; Mature: 34659

Theoretical pI: Translated: 9.36; Mature: 9.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGESKKKAARSGRNAPPSGISGADAPSKLHTLIDDFCEHLDLVVGRSAATIRGYRSDLYA
CCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
MADTIEDIDNFSLPTLRQWLGIAVDEGKSRATLARRTASVKAFSSWAQKNGHLKADEAAR
HHHHHHHHHCCCCHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
LISPKITRDLPKILGEQQAGDFVENAASTNEEEFLRDSAILELLYATGMRVAELCGIDLP
HHCCHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCHHHHHHHCCCCC
DIDYDRKMVRVLGKGNKERVVPFGESAHKALRNWLDVRDEMAEDPKALFVGVRGQRINAR
CCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHH
QVRRIVDRVAKVTGVDHLSPHSLRHTAATHLLDGGADLRQVQELLGHSSMQTTQIYTHVS
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHH
NKRLLEAFNKAHPRA
HHHHHHHHHHCCCCC
>Mature Secondary Structure 
GESKKKAARSGRNAPPSGISGADAPSKLHTLIDDFCEHLDLVVGRSAATIRGYRSDLYA
CCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
MADTIEDIDNFSLPTLRQWLGIAVDEGKSRATLARRTASVKAFSSWAQKNGHLKADEAAR
HHHHHHHHHCCCCHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
LISPKITRDLPKILGEQQAGDFVENAASTNEEEFLRDSAILELLYATGMRVAELCGIDLP
HHCCHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCHHHHHHHCCCCC
DIDYDRKMVRVLGKGNKERVVPFGESAHKALRNWLDVRDEMAEDPKALFVGVRGQRINAR
CCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHH
QVRRIVDRVAKVTGVDHLSPHSLRHTAATHLLDGGADLRQVQELLGHSSMQTTQIYTHVS
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHH
NKRLLEAFNKAHPRA
HHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12948626 [H]