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The map label for this gene is map [H]

Identifier: 145294723

GI number: 145294723

Start: 728852

End: 729646

Strand: Direct

Name: map [H]

Synonym: cgR_0671

Alternate gene names: 145294723

Gene position: 728852-729646 (Clockwise)

Preceding gene: 145294722

Following gene: 145294724

Centisome position: 21.99

GC content: 60.5

Gene sequence:

>795_bases
ATGGGTTTCCGTTCCAAGAAGAAGGTTATTGCGGCAAAGACCGCCGCTGAGCTGGACGCGATGCAGGCGGCGGGTGAGAT
CGTCGGCAAGGCTTTGCAGGCTGTGCGCGCTGAGGCTAAAGCTGGCATGAGCACGTGGGATCTGGATCAGATCGCGGAGC
AGGTTATCCGCGATGCTGGCGCCGTTCCTACATTCCTGGGTTACCAGGGTTTTCCGGCATCAGTGTGCGCTTCGGTCAAT
GAGGTGATTGTTCACGGCATTCCATCCAAGGAGACCATCTTGGAGGAAGGCGATCTGGTGTCCATCGACTGCGGCGCAAC
CTTTGATGGTTGGGTCGGCGATTCCGCGTGGAGCTTCGGCATCGGCGAGCTGGACGAGGACGTCCAGGGTCTCAACTTGG
CTACCGAGTGGGTCCTCATGGAAGGCATGAAGGCCATGGTTCCAGGCAACCGTTTGACCGATGTCTCCCACGCTCTCGAG
GTCGCAACCCGCAAGGCTGAGTCCAAGTTCGGCGTCGTGCTTGGCATCGTCGATGGCTACGGCGGACACGGCATTGGCCG
CCACATGCACGAGGAGCCATACTTGGCTAATGAGGGCAAGGCTGGCAAGGGCCCTGTGATTCAGGAGGGCTCCGTGCTCG
CCATCGAGCCTATGCTCACCCTCGGCACCGAAGATTCCGCAGTGCTGGAAGATGATTGGACTGTCGTGACCCTCGACGGT
TCATGGGCAGCGCACTGGGAGCACACCGTTGCAGCCACCAAGGGCGGCCCGCGCATCCTCACCCCGCGTTATTAA

Upstream 100 bases:

>100_bases
GTGGAAGCACTCACCTCAAGGTGGCCGGAACCGCATGCATTGTGCGGTGCCGGCCACCTTTGGTTTTAACAGTTTAATTT
GAAGAAAGAGACGTGGAAGC

Downstream 100 bases:

>100_bases
AATGATGCTTTTCGACGCATCCCCGCGTTTTCGGGGCTAAAAGTTGCCCGGTTGAGCAAAGGTTTGCGACCTCCCCGGCG
TGCCGCCAGGGGAGGAGGCG

Product: methionine aminopeptidase

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 264; Mature: 263

Protein sequence:

>264_residues
MGFRSKKKVIAAKTAAELDAMQAAGEIVGKALQAVRAEAKAGMSTWDLDQIAEQVIRDAGAVPTFLGYQGFPASVCASVN
EVIVHGIPSKETILEEGDLVSIDCGATFDGWVGDSAWSFGIGELDEDVQGLNLATEWVLMEGMKAMVPGNRLTDVSHALE
VATRKAESKFGVVLGIVDGYGGHGIGRHMHEEPYLANEGKAGKGPVIQEGSVLAIEPMLTLGTEDSAVLEDDWTVVTLDG
SWAAHWEHTVAATKGGPRILTPRY

Sequences:

>Translated_264_residues
MGFRSKKKVIAAKTAAELDAMQAAGEIVGKALQAVRAEAKAGMSTWDLDQIAEQVIRDAGAVPTFLGYQGFPASVCASVN
EVIVHGIPSKETILEEGDLVSIDCGATFDGWVGDSAWSFGIGELDEDVQGLNLATEWVLMEGMKAMVPGNRLTDVSHALE
VATRKAESKFGVVLGIVDGYGGHGIGRHMHEEPYLANEGKAGKGPVIQEGSVLAIEPMLTLGTEDSAVLEDDWTVVTLDG
SWAAHWEHTVAATKGGPRILTPRY
>Mature_263_residues
GFRSKKKVIAAKTAAELDAMQAAGEIVGKALQAVRAEAKAGMSTWDLDQIAEQVIRDAGAVPTFLGYQGFPASVCASVNE
VIVHGIPSKETILEEGDLVSIDCGATFDGWVGDSAWSFGIGELDEDVQGLNLATEWVLMEGMKAMVPGNRLTDVSHALEV
ATRKAESKFGVVLGIVDGYGGHGIGRHMHEEPYLANEGKAGKGPVIQEGSVLAIEPMLTLGTEDSAVLEDDWTVVTLDGS
WAAHWEHTVAATKGGPRILTPRY

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI40385867, Length=259, Percent_Identity=32.8185328185328, Blast_Score=137, Evalue=9e-33,
Organism=Homo sapiens, GI164420681, Length=254, Percent_Identity=31.496062992126, Blast_Score=135, Evalue=4e-32,
Organism=Escherichia coli, GI1786364, Length=255, Percent_Identity=34.9019607843137, Blast_Score=161, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI71996291, Length=258, Percent_Identity=32.1705426356589, Blast_Score=136, Evalue=1e-32,
Organism=Saccharomyces cerevisiae, GI6323273, Length=248, Percent_Identity=32.6612903225806, Blast_Score=137, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24583427, Length=249, Percent_Identity=32.1285140562249, Blast_Score=143, Evalue=1e-34,
Organism=Drosophila melanogaster, GI21355531, Length=247, Percent_Identity=31.9838056680162, Blast_Score=139, Evalue=3e-33,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 27973; Mature: 27842

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFRSKKKVIAAKTAAELDAMQAAGEIVGKALQAVRAEAKAGMSTWDLDQIAEQVIRDAG
CCCCCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCC
AVPTFLGYQGFPASVCASVNEVIVHGIPSKETILEEGDLVSIDCGATFDGWVGDSAWSFG
CCCHHHCCCCCCHHHHHHHHHHHEECCCCHHHHHCCCCEEEEECCCCCCCCCCCCCCCCC
IGELDEDVQGLNLATEWVLMEGMKAMVPGNRLTDVSHALEVATRKAESKFGVVLGIVDGY
CCCCCHHHHCCHHHHHHHHHHCHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCC
GGHGIGRHMHEEPYLANEGKAGKGPVIQEGSVLAIEPMLTLGTEDSAVLEDDWTVVTLDG
CCCCCCCCCCCCCCCCCCCCCCCCCEEECCCEEEECCEEEECCCCCEEEECCCEEEEECC
SWAAHWEHTVAATKGGPRILTPRY
CEEECCCEEEEECCCCCEECCCCC
>Mature Secondary Structure 
GFRSKKKVIAAKTAAELDAMQAAGEIVGKALQAVRAEAKAGMSTWDLDQIAEQVIRDAG
CCCCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCC
AVPTFLGYQGFPASVCASVNEVIVHGIPSKETILEEGDLVSIDCGATFDGWVGDSAWSFG
CCCHHHCCCCCCHHHHHHHHHHHEECCCCHHHHHCCCCEEEEECCCCCCCCCCCCCCCCC
IGELDEDVQGLNLATEWVLMEGMKAMVPGNRLTDVSHALEVATRKAESKFGVVLGIVDGY
CCCCCHHHHCCHHHHHHHHHHCHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCC
GGHGIGRHMHEEPYLANEGKAGKGPVIQEGSVLAIEPMLTLGTEDSAVLEDDWTVVTLDG
CCCCCCCCCCCCCCCCCCCCCCCCCEEECCCEEEECCEEEECCCCCEEEECCCEEEEECC
SWAAHWEHTVAATKGGPRILTPRY
CEEECCCEEEEECCCCCEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]